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The map label for this gene is rmaC

Identifier: 15673454

GI number: 15673454

Start: 1502314

End: 1503384

Strand: Reverse

Name: rmaC

Synonym: L102062

Alternate gene names: 15673454

Gene position: 1503384-1502314 (Counterclockwise)

Preceding gene: 15673455

Following gene: 15673453

Centisome position: 63.55

GC content: 31.93

Gene sequence:

>1071_bases
ATGAAGCTTGAAAAAGTCAGCCAGTTACTCTATCAGCTCAAAATTGTAAATCAAGAAATGACGGCAAAATTTGAGAAGTC
AACGGGTTATAGTATTACTCGTTATCAACTGATGATGATTTTAAAATGTAAAGGTCGTTGCTCTCAAAGTCAATTACAAA
ATGAATTAAAAATTGATAGTGCTGCTGTAACAAGACATTTAAAATTACTTGAAGAAAAAAATCTTGTCAAAAGAGAGCGC
AATAAAGAAAATAATCGAGAAGTATTTGTCGAAATTACCGATAAAGCTAAAAATGATTTAGCACTTTGTGCAAAAAAACA
TGATGATTCTCTAGATGAAAGTCAACAAATATTAAATATTGGGCTCAGTCGATTTAGAAGAAGAACAACTTTTAGAACTA
CTCACAAAATTAACACAATGAAAGAAGAAAAAATGAATAAGAACTTTATAAATGACGATTTCTCAGATATTACTTTTGGT
AGAAAATCTGTCAGACTTTATGTTGAAAACTACAAAATTTCTCACGAAGAAATGCTTGAAATGATTCAAGAAGCAACAGC
TGCACCTTCATCAGTAAATATGCAACCTTGGCGTTTTATCATTGCTGAAACCGAAGAATCAAAAGCAAAATTAAAACCTT
TAATTCGCTTTAACACACGTCAAAATGATACTTCATCAGCAATGATTTTAATTTTTGGTGACATGCTTAATTATGAATTA
GGTGAAGAAATCTATGACCAAGCAGTTGCTGAAGGAAAAATGCCTCAGGAAGCCAGAGATCAACAAATTGGAGCAATTAT
TCCTTATTACAAGAGTTTTTCTAAACAAGAAATGAATGATGTTGTCAAAATTGACTCAAGTTTGGCAGCAATGCAATTGA
TGTTGGTGGCAAGAGCTCATGGTTATGAAACAAATCCAATTGGTGGTTTTGAAAAAGATCAATTAGCAGAAGCTTTCGAT
TTAGACAAAGAACGTTTTGTCCCAGTTATGATTTTGTCAATTGGTAAAGCCGTTGAAGAAGGTTATGAATCTGTCCGCAT
GAATGCTGATAAAATCACTACTTTTAAATAA

Upstream 100 bases:

>100_bases
TTTTTTATTTCTCAATTCTTTTAGTTGTAATTTATTTATTTTAATACTATAATTGACTAATCAATGATTGACAAATCAAT
TAAGAAAGGAGAAATAAATT

Downstream 100 bases:

>100_bases
AAAGGAGAAGTAATTTGACCATTTTAACAATTATTCTGTCGCTTTTGGTTGCTTTGGAATTTTTCTACATTATGTATTTA
GAGACCTTTGCTACAAGCTC

Product: transcription regulator

Products: NAD(P)(+); @TETR01.txt*5,6,7,8-Tetrahydropteridine!. [C]

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MKLEKVSQLLYQLKIVNQEMTAKFEKSTGYSITRYQLMMILKCKGRCSQSQLQNELKIDSAAVTRHLKLLEEKNLVKRER
NKENNREVFVEITDKAKNDLALCAKKHDDSLDESQQILNIGLSRFRRRTTFRTTHKINTMKEEKMNKNFINDDFSDITFG
RKSVRLYVENYKISHEEMLEMIQEATAAPSSVNMQPWRFIIAETEESKAKLKPLIRFNTRQNDTSSAMILIFGDMLNYEL
GEEIYDQAVAEGKMPQEARDQQIGAIIPYYKSFSKQEMNDVVKIDSSLAAMQLMLVARAHGYETNPIGGFEKDQLAEAFD
LDKERFVPVMILSIGKAVEEGYESVRMNADKITTFK

Sequences:

>Translated_356_residues
MKLEKVSQLLYQLKIVNQEMTAKFEKSTGYSITRYQLMMILKCKGRCSQSQLQNELKIDSAAVTRHLKLLEEKNLVKRER
NKENNREVFVEITDKAKNDLALCAKKHDDSLDESQQILNIGLSRFRRRTTFRTTHKINTMKEEKMNKNFINDDFSDITFG
RKSVRLYVENYKISHEEMLEMIQEATAAPSSVNMQPWRFIIAETEESKAKLKPLIRFNTRQNDTSSAMILIFGDMLNYEL
GEEIYDQAVAEGKMPQEARDQQIGAIIPYYKSFSKQEMNDVVKIDSSLAAMQLMLVARAHGYETNPIGGFEKDQLAEAFD
LDKERFVPVMILSIGKAVEEGYESVRMNADKITTFK
>Mature_356_residues
MKLEKVSQLLYQLKIVNQEMTAKFEKSTGYSITRYQLMMILKCKGRCSQSQLQNELKIDSAAVTRHLKLLEEKNLVKRER
NKENNREVFVEITDKAKNDLALCAKKHDDSLDESQQILNIGLSRFRRRTTFRTTHKINTMKEEKMNKNFINDDFSDITFG
RKSVRLYVENYKISHEEMLEMIQEATAAPSSVNMQPWRFIIAETEESKAKLKPLIRFNTRQNDTSSAMILIFGDMLNYEL
GEEIYDQAVAEGKMPQEARDQQIGAIIPYYKSFSKQEMNDVVKIDSSLAAMQLMLVARAHGYETNPIGGFEKDQLAEAFD
LDKERFVPVMILSIGKAVEEGYESVRMNADKITTFK

Specific function: Reduction Of A Variety Of Nitroaromatic Compounds Using NADH (And To Lesser Extent Nadph) As Source Of Reducing Equivalents; Two Electrons Are Transferred. Capable Of Reducing Nitrofurazone, Quinones And The Anti-Tumor Agent Cb1954 (5- (Aziridin-1-Yl)-2,4

COG id: COG0778

COG function: function code C; Nitroreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitroreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000415 [H]

Pfam domain/function: PF00881 Nitroreductase [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 41180; Mature: 41180

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLEKVSQLLYQLKIVNQEMTAKFEKSTGYSITRYQLMMILKCKGRCSQSQLQNELKIDS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCHH
AAVTRHLKLLEEKNLVKRERNKENNREVFVEITDKAKNDLALCAKKHDDSLDESQQILNI
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHH
GLSRFRRRTTFRTTHKINTMKEEKMNKNFINDDFSDITFGRKSVRLYVENYKISHEEMLE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCEEEEEEECCCCCHHHHHH
MIQEATAAPSSVNMQPWRFIIAETEESKAKLKPLIRFNTRQNDTSSAMILIFGDMLNYEL
HHHHHHCCCCCCCCCCEEEEEEECCHHHHHHCHHHEECCCCCCCCCEEEEEEEHHHCHHH
GEEIYDQAVAEGKMPQEARDQQIGAIIPYYKSFSKQEMNDVVKIDSSLAAMQLMLVARAH
HHHHHHHHHHCCCCCHHHHHHHCCEEEHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHC
GYETNPIGGFEKDQLAEAFDLDKERFVPVMILSIGKAVEEGYESVRMNADKITTFK
CCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCC
>Mature Secondary Structure
MKLEKVSQLLYQLKIVNQEMTAKFEKSTGYSITRYQLMMILKCKGRCSQSQLQNELKIDS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCHH
AAVTRHLKLLEEKNLVKRERNKENNREVFVEITDKAKNDLALCAKKHDDSLDESQQILNI
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHH
GLSRFRRRTTFRTTHKINTMKEEKMNKNFINDDFSDITFGRKSVRLYVENYKISHEEMLE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCEEEEEEECCCCCHHHHHH
MIQEATAAPSSVNMQPWRFIIAETEESKAKLKPLIRFNTRQNDTSSAMILIFGDMLNYEL
HHHHHHCCCCCCCCCCEEEEEEECCHHHHHHCHHHEECCCCCCCCCEEEEEEEHHHCHHH
GEEIYDQAVAEGKMPQEARDQQIGAIIPYYKSFSKQEMNDVVKIDSSLAAMQLMLVARAH
HHHHHHHHHHCCCCCHHHHHHHCCEEEHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHC
GYETNPIGGFEKDQLAEAFDLDKERFVPVMILSIGKAVEEGYESVRMNADKITTFK
CCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FMN. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NAD(P)H; 6,7-Dihydropteridine [C]

Specific reaction: NAD(P)H + 6,7-Dihydropteridine = NAD(P)(+) + @TETR01.txt*5,6,7,8-Tetrahydropteridine!. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]