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The map label for this gene is nagA

Identifier: 15673317

GI number: 15673317

Start: 1373323

End: 1374471

Strand: Reverse

Name: nagA

Synonym: L173068

Alternate gene names: 15673317

Gene position: 1374471-1373323 (Counterclockwise)

Preceding gene: 15673318

Following gene: 15673316

Centisome position: 58.1

GC content: 41.6

Gene sequence:

>1149_bases
ATGACTTACTATATTAAAGCAGATCAATTTTTCTACGCTTATGAAACAAAAAAAGGTGGTTTCTTAGAAATTACTGATGG
AAAATTTGGAGAGTGGACAGAAGAAGCACCAGCAGGAGCTGACATTTTAGATTATTCAGGTCAATCAATTGCCCCAGGTC
TTGTTGAAACACATATCCATGGTTTTGGTGGAGCGGATGCCCAAGATGCTGAAGTTGAAGGAATTATGGGAACAATGTCA
GAAGGCTTGTTGTCAGCAGGGGTCACATCATTTTTACCAAGTCCTTTGACCGATGATCATGAAGGATTGAAAGCAGTTTG
TACGGTTGTAGGAGAACATTACCAAGAAGCTCGCGGAGCCAAAGTTCGTGGTATTTTCTTTGAAGGTCCATTCTTTACAG
AGGAAAAGAAAGGGGCTCAAAACCCTAAATACATGCGCGATGCCAAAATGTGGGAACTTGAAGATTGGCAAGAAGCTGCA
CATGGAATGCTCAAAAAAATCGGTCTTGCCCCAGAACGTGATGGTTCAGAAGACTTCATCCGTAAAGCAACTGAATCAGG
TGTTGTTATTGCATTGGGACATTCAAATGCGACTTATAAACAAGCAGTTGCTGGGGTACAAGCTGGAGCATCTGTTTGGG
TTCACACCTTTAACGGAATGTCTGGAATGACTCACCAAGAACCAGGAATGGTTGGAGCAATTTTAAATACACCAAACACT
TATGCTGAGTTAATTTGTGATGGTCACCATGTTCGTCCAGAAGCAGCTGAAATTGTAATGAAAATGAAAGGTGCTGACCA
TGTTGTTTTGATTACAGACTCAATGCGTGCCGCAGGACTTCCTGACGGACCTTATATGCTTGGCGAATACGAAGTAGAAG
TTCGTGACGGAGCCGCATGGCTTCCAACAGGACGCCCTGCTGCTTCAATTTTAACACTCAAAACAGCTGTTAAAAATGTC
ATTGACTGGGGGATTGCCACACCAGCAGAAGCAATTATGATGGCTTCATTGACACCAGCAAAATCTGTAAACATTGATGA
TGTTTGTGGTCAAATAAAACCAGGTTTGTCAGCTGATTTTATCGTTTTAGACAATGATTTTGATTTAGTTGCAACTTATC
TTGATGGTGAAAAACGCTATGAAGCGTAA

Upstream 100 bases:

>100_bases
AATCTGTCAGTAATTTTTTATAGTGATAATTGGTATATACTGTTTATTGACAAAAAAGATAAAGGGTGCTAAAATTAAAG
AAAAAGAAGAGGAGATATTT

Downstream 100 bases:

>100_bases
TATAAAAAATGAATTTCGCAAGGAATTCATTTTTTTATGAAAATATTTCATTTTTCAAGTTGAATAATCAGAAAAATAAA
CAAAAAGGTAAAAGATTATT

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MTYYIKADQFFYAYETKKGGFLEITDGKFGEWTEEAPAGADILDYSGQSIAPGLVETHIHGFGGADAQDAEVEGIMGTMS
EGLLSAGVTSFLPSPLTDDHEGLKAVCTVVGEHYQEARGAKVRGIFFEGPFFTEEKKGAQNPKYMRDAKMWELEDWQEAA
HGMLKKIGLAPERDGSEDFIRKATESGVVIALGHSNATYKQAVAGVQAGASVWVHTFNGMSGMTHQEPGMVGAILNTPNT
YAELICDGHHVRPEAAEIVMKMKGADHVVLITDSMRAAGLPDGPYMLGEYEVEVRDGAAWLPTGRPAASILTLKTAVKNV
IDWGIATPAEAIMMASLTPAKSVNIDDVCGQIKPGLSADFIVLDNDFDLVATYLDGEKRYEA

Sequences:

>Translated_382_residues
MTYYIKADQFFYAYETKKGGFLEITDGKFGEWTEEAPAGADILDYSGQSIAPGLVETHIHGFGGADAQDAEVEGIMGTMS
EGLLSAGVTSFLPSPLTDDHEGLKAVCTVVGEHYQEARGAKVRGIFFEGPFFTEEKKGAQNPKYMRDAKMWELEDWQEAA
HGMLKKIGLAPERDGSEDFIRKATESGVVIALGHSNATYKQAVAGVQAGASVWVHTFNGMSGMTHQEPGMVGAILNTPNT
YAELICDGHHVRPEAAEIVMKMKGADHVVLITDSMRAAGLPDGPYMLGEYEVEVRDGAAWLPTGRPAASILTLKTAVKNV
IDWGIATPAEAIMMASLTPAKSVNIDDVCGQIKPGLSADFIVLDNDFDLVATYLDGEKRYEA
>Mature_381_residues
TYYIKADQFFYAYETKKGGFLEITDGKFGEWTEEAPAGADILDYSGQSIAPGLVETHIHGFGGADAQDAEVEGIMGTMSE
GLLSAGVTSFLPSPLTDDHEGLKAVCTVVGEHYQEARGAKVRGIFFEGPFFTEEKKGAQNPKYMRDAKMWELEDWQEAAH
GMLKKIGLAPERDGSEDFIRKATESGVVIALGHSNATYKQAVAGVQAGASVWVHTFNGMSGMTHQEPGMVGAILNTPNTY
AELICDGHHVRPEAAEIVMKMKGADHVVLITDSMRAAGLPDGPYMLGEYEVEVRDGAAWLPTGRPAASILTLKTAVKNVI
DWGIATPAEAIMMASLTPAKSVNIDDVCGQIKPGLSADFIVLDNDFDLVATYLDGEKRYEA

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=394, Percent_Identity=29.6954314720812, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI224922791, Length=376, Percent_Identity=30.0531914893617, Blast_Score=144, Evalue=2e-34,
Organism=Escherichia coli, GI1786892, Length=385, Percent_Identity=29.3506493506493, Blast_Score=155, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17553768, Length=397, Percent_Identity=25.1889168765743, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI19920392, Length=344, Percent_Identity=30.8139534883721, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI281361140, Length=358, Percent_Identity=29.8882681564246, Blast_Score=145, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41178; Mature: 41047

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYYIKADQFFYAYETKKGGFLEITDGKFGEWTEEAPAGADILDYSGQSIAPGLVETHIH
CEEEEEECEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHCC
GFGGADAQDAEVEGIMGTMSEGLLSAGVTSFLPSPLTDDHEGLKAVCTVVGEHYQEARGA
CCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
KVRGIFFEGPFFTEEKKGAQNPKYMRDAKMWELEDWQEAAHGMLKKIGLAPERDGSEDFI
EEEEEEECCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHH
RKATESGVVIALGHSNATYKQAVAGVQAGASVWVHTFNGMSGMTHQEPGMVGAILNTPNT
HHHCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCH
YAELICDGHHVRPEAAEIVMKMKGADHVVLITDSMRAAGLPDGPYMLGEYEVEVRDGAAW
HHHHEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEEEEEEEEECCEEE
LPTGRPAASILTLKTAVKNVIDWGIATPAEAIMMASLTPAKSVNIDDVCGQIKPGLSADF
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCEEE
IVLDNDFDLVATYLDGEKRYEA
EEEECCCEEEEEEECCCHHCCC
>Mature Secondary Structure 
TYYIKADQFFYAYETKKGGFLEITDGKFGEWTEEAPAGADILDYSGQSIAPGLVETHIH
EEEEEECEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHCC
GFGGADAQDAEVEGIMGTMSEGLLSAGVTSFLPSPLTDDHEGLKAVCTVVGEHYQEARGA
CCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
KVRGIFFEGPFFTEEKKGAQNPKYMRDAKMWELEDWQEAAHGMLKKIGLAPERDGSEDFI
EEEEEEECCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHH
RKATESGVVIALGHSNATYKQAVAGVQAGASVWVHTFNGMSGMTHQEPGMVGAILNTPNT
HHHCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCH
YAELICDGHHVRPEAAEIVMKMKGADHVVLITDSMRAAGLPDGPYMLGEYEVEVRDGAAW
HHHHEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEEEEEEEEECCEEE
LPTGRPAASILTLKTAVKNVIDWGIATPAEAIMMASLTPAKSVNIDDVCGQIKPGLSADF
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCEEE
IVLDNDFDLVATYLDGEKRYEA
EEEECCCEEEEEEECCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969210 [H]