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The map label for this gene is gltB

Identifier: 15673268

GI number: 15673268

Start: 1316521

End: 1320981

Strand: Reverse

Name: gltB

Synonym: L0119

Alternate gene names: 15673268

Gene position: 1320981-1316521 (Counterclockwise)

Preceding gene: 15673270

Following gene: 15673267

Centisome position: 55.84

GC content: 38.96

Gene sequence:

>4461_bases
ATGAATAAAAAAGCTAAACAAGCCATGAAAACGACACTTTGGCAGCCTGATTTTGAATCGGATGCTTGTGGAATGGGCTT
CATTGCCCAAATTGACGGGAAAGCTAGTCACCTTTTAGTTGAGAGAGCGCTGACCATGTTAACAAGGATGAATCATCGTG
GTGGAACGGGTGCTGAACCAGAAACTGGAGATGGGGCAGGTATTTTACTTGCTTTGCCTGACGAATTCTTTCGTAAAATT
GCAAAAGAACATGATGTAGAACTACCAAAACTTGGTGATTATGCCGTAGGGCAATTTTTCTTATCACGTAAGGAAAATAA
AAAACATCAAGAATTAGAAGCGATTAAGGCAGCTGTTAAGGCTCAAGGATATGAAGTCTTATTCACGCGCACAGTTCCTT
TTAATTTTGAAGCATGTGGAGCAACGGCTCAAGGAATTATGCCGTCTTTTGTTCAAGTTTTTATTGAGAAAAAATCATCT
GAAAAAGCTGTCAGCGAAATTTCTAATTTTGAAAATGATTTATTTATTATCAGACGAAATCTTGAAAAACGTTTTGACGA
AGAGGAATTATATATTTGTTCATTATCTAGTCAGACGGTTGTTTATAAGGGAATGCTTCACGCGTATCAAGTAAAACTCT
TTTATCCTGATTTGTCTGATGAAGATTTCAAAAGTCATATTGCACTAACACATAGCCGTTTTTCTACCAATACTTTTCCC
TCTTGGAATCGGGCTCAACCTTTTCGTTTTCTAGCACATAATGGCGAAATTAACACGCTTCGCGGAGCTGAAAACTGGAT
GAAAGTTAACGATATTGAAATGTACAATGAAGAAAATTCTGATTCAGCCAAATTAGAAAATTGTATGGAGTATTTCTATC
GAAATGGTCGAGAACTTCCAGAAAGTTTACTGACCATGATTCCTGAGGCTTGGGGAGAACAAACTGGCTTAAGTCCAGAA
TTGAAAGCTTTTTACGAATATTCAACTGCTCATATTGCGCCTTGGGATGGACCGGCAGCTTTAGTATTTACTGACGGAAA
AACCGTTGGGGCAAGACTTGATCGGAATGGTTTAAGACCAAGTCGTTATCTTGTGACAAAGGATAATTCTATCATTCTGT
CAAGCGAATCTGGTGTGGTTGATATCCCAGCCGATGAAATCATTGAAAAATCAGTTCTTGGACCTGGTAACATGTTGTTA
GTAAATACTGACGAAGGAAAAATTATTCGTAATGAAGAAGTTAAGAGTTATTATGCTAATAAATATCCCTACCAAGAATT
TCTGTCAGCAGGTTTGAAAAAACTGTCAGCACTGACAGAAAGTGAAAAAACAAATCCAATTCCGTCAGCAAAAATGAATA
CCTTATGGAAATTATTTGGTTATACTGACGAAGTCATTCGGACAGTGCTTTTACCAATGGCGGAATCAGCCAATGAACCT
ACAATTTCAATGGGCTTTGATGCTCCTTTGGCAGTTTTATCTGACCAAGCTCAATCACTTTATAATTTCTTCAAACAACA
ATTTGCTCAAGTGACCAATCCGCCAATTGATGCGATTAGGGAACAAATTGTCATTGGAACGGAAACCTATTTGGGAGAAG
ATGGGAATCCAGCAAAAATCACAGGTGAAAATGTCCGTAAGTTAAAATTAGACAGTCCAGTCCTTTCAACGGCTGACTTT
GAAAAAATCTTAGCATTGAAGGAAGAACATTATCATACAGAAATTATTTCCACCCTTTATGATAAGGATGACCTTTTAGA
AAATGCATTGAACAAACTCTTTTATAAGGCAGAAAGTTTGATTAATCAAGGAACAACTATTATCGTGCTTTCTGACCGTG
ACTTTGCTGAAAATAAAGTGCCGATGCCTATTTTACTTGCTTTGTCAGGACTTTATCATTATATGTTAGGACGTCATAAT
GCGTCTAAATTTGCAATTATTGTAGATACAGCTGAGGTGTGCGAAGTTCATCAATTTGCAGCGCTTGTAGGCTATGGCGT
ATCAGGAATTCATCCTTATGGTGCATATGCAACCCTTTCAGACTGGGGTATGGGAGCACCTGAACAACTTGAAAATTTCC
GTCATGCGGCAGAAAAAGGTATTGTTAAGGTCATGAGTCGGATGGGAATTTCAACAATTGTCGGTTATAAAGGGGCTCAA
CTTTTTGAAGCAATTGGTTTATCTAAAGAAGTCGTTGACAAGTACTTCACAGGTACGAGTACAAGAATTGGTGGACTTTC
TCTTGCCCAAATTGAGGACGAATATCGTTTGCGATATGAGAAAGCTTATGGACATCGGGCACAGGATTTATTGGAAACAG
GCGGTTCTTTCCAATACCGGGCGGATGAAGGAGAACATCATATCTATGACCCACAAATGATTTACCAAATTCAAAATGCT
GTCCGTCAAAATGATTTTGAAAAATATAAAAAATATAGTCAGTATCTAAATGATATTGCTCTAAAAACGCCGACAAGCTT
ACGTCACACTTGGAAAATCAAATCTGATCGGAAGTCCATTCAGATGAGCGAAGTAGAACCAGCTCGTGAAATTGTTAAAC
GTTTCAAAATTGGGGCCATGTCATTTGGATCATTGTCACAAGAGGCTCACGAATGTATTGCTCAAGCTATGAACTCTATT
GGTGCAAAATCCAATTCGGGTGAAGGTGGTGAAAATGCAAAACGTTATGGCACAATCAATAATTCTAAAATTAAACAAGT
CGCCTCTGGACGATTTGGTGTGTCAGCTGCTTATTTAATGTCTGCCGAAGAGATTCAAATTAAAATTTCGCAAGGTGCTA
AACCAGGTGAAGGTGGGCAATTGCCAGGTAAAAAAGCTTTTCCTTGGGTGGCAGAAGTTCGAAACTCAACTCCAGGGGTA
AGTTTAATTTCACCACCGCCTCATCATGATATTTATTCCATTGAAGATTTGTCGCAACTTATTTTTGACTTGAAAAAAAT
TAATCCTTATGCAAAAATCAACGTTAAGTTGGTTTCATCGACTGGTGTTGGAACAATTGCTACAGGATGTGTTAAGGCCG
GAGCTGATAAAGTTGTTATTTCTGGTTATGATGGTGGAACTGGAGCAAGTCCTAGAAACTCAATAAGAGATGCAGGTCTC
CCTTGGGAAATGGGACTGGCAGAAGCACATCAAACGCTTAGTTTGAACAATTTACGTGACCGAATGATTTTGGAAACTGA
TGGTAAAGTAGTCACAGGTCGAGATATTGCGATTGCTGCAATGCTAGGTGCTGAAGAATATTCATTTGGTAGTTTAGCTT
TGGTTGCGATTGGATGTATCATGACAAGAAATTGTCATTTAAATACTTGTCCCGTAGGTATTGCCACACAAAATCCTAGA
TTAAGAGCAAATTTTGCTGGAAACCCAGAGCACATTGTACGCTTAATGGAATTTATGGCTGAGGAAGTTCGAGAACTTTT
AGCCGAACTTGGTTTTAGAACAATCAATGAATTGGTAGGTCATGCCGAGCTCTTGCAAGCTAAAGAAGATTTACCAGCTA
AAATGCGAGGTTTGGACTTTAGCCGTATGCTTGGTCATGCCTTACCGATTGCAACAAGACATAGTGATCCTTTTGCTAAT
CCTCGTGCTTGGAAAGAGTTAGACCAATTTACGGAGGCTACACTTAATAATGGTTCTCAAGCAACGGTTCATGGCACGAT
TAAAAATATTAATCGAACAACGACCGCGCGGATGGCAGGTTGGATTGCTGAACGTTATGGTAATTTTGGTCTAAAAGATG
CTTCTGTTTGCTATGAATATGAAGGGGTTGCTGGCCAGTCCTTTGGCTCTTACGCAACCGCTGGTATGGAGGTTACTCTG
ATTGGCGAAGCCAATGATTATATTGGAAAATCATTGTCAGGTGGCCGTTTGATTGTAAAACCACCTCTAGATGCTGCTTA
TGATATTGAAAATACTTCTATTGTTGGGAATGTTTCGCTCTTTGGGGCTATCGGTGGCGAAGCTTATTTCCGAGGTCGTG
CAGGTGAGCGCTGTGGTGTCCGAAATTCAGGAGCACATTTTGTTGTGGAAGGAACGGGTGACCATGGTTGTGAATACATG
ACTGGTGGTATCGCTGTTGTTCTTGGTACAACAGGTCGTAATTTTGCGGCTGGGATGTCTGGTGGTATCGCTTATGTTTA
TGATGTCGCTGGCAATTTTGAAAATAAAGTGAATCGGGAAATGGTAGATCTTTATGCTTTAGATGAAACTTCAGGTGATG
AAGTTTTAGAAGAATTATTGAAGAAACATTTGAATTATACTGATTCAGAAAAAGCAAAATTCATTTTAGAACATTGGCAA
ACAGAACGCGAAAAATTTGTCAAAGTTTATCCAAGAGAATATCATCATATTAAAAATGTTGAAGAAGATTTGGCTAAAAC
AGGCTTGTCAGGCGAAGCACTTACGATGACAACCTTTAAAAAAGTAACGGAGGTGAGCTAA

Upstream 100 bases:

>100_bases
TAAAAATTACATTTATATATAATTGTCAGAATATATTGATATTTCATCGAAATTTTAGTAGAATAAAAGAACCAAATTGT
AAAATAAAAGAGGTTGTGTT

Downstream 100 bases:

>100_bases
TGGCTGATCCAAATGGATTTTTAAATTATCCAAGAAATGATAATCCTTACCGTGAATTAGCGGAGCGGATAAAGGATTTT
GCTGAACTGCAAGTTCCCTT

Product: glutamate synthase large subunit

Products: NA

Alternate protein names: NADPH-GOGAT [H]

Number of amino acids: Translated: 1486; Mature: 1486

Protein sequence:

>1486_residues
MNKKAKQAMKTTLWQPDFESDACGMGFIAQIDGKASHLLVERALTMLTRMNHRGGTGAEPETGDGAGILLALPDEFFRKI
AKEHDVELPKLGDYAVGQFFLSRKENKKHQELEAIKAAVKAQGYEVLFTRTVPFNFEACGATAQGIMPSFVQVFIEKKSS
EKAVSEISNFENDLFIIRRNLEKRFDEEELYICSLSSQTVVYKGMLHAYQVKLFYPDLSDEDFKSHIALTHSRFSTNTFP
SWNRAQPFRFLAHNGEINTLRGAENWMKVNDIEMYNEENSDSAKLENCMEYFYRNGRELPESLLTMIPEAWGEQTGLSPE
LKAFYEYSTAHIAPWDGPAALVFTDGKTVGARLDRNGLRPSRYLVTKDNSIILSSESGVVDIPADEIIEKSVLGPGNMLL
VNTDEGKIIRNEEVKSYYANKYPYQEFLSAGLKKLSALTESEKTNPIPSAKMNTLWKLFGYTDEVIRTVLLPMAESANEP
TISMGFDAPLAVLSDQAQSLYNFFKQQFAQVTNPPIDAIREQIVIGTETYLGEDGNPAKITGENVRKLKLDSPVLSTADF
EKILALKEEHYHTEIISTLYDKDDLLENALNKLFYKAESLINQGTTIIVLSDRDFAENKVPMPILLALSGLYHYMLGRHN
ASKFAIIVDTAEVCEVHQFAALVGYGVSGIHPYGAYATLSDWGMGAPEQLENFRHAAEKGIVKVMSRMGISTIVGYKGAQ
LFEAIGLSKEVVDKYFTGTSTRIGGLSLAQIEDEYRLRYEKAYGHRAQDLLETGGSFQYRADEGEHHIYDPQMIYQIQNA
VRQNDFEKYKKYSQYLNDIALKTPTSLRHTWKIKSDRKSIQMSEVEPAREIVKRFKIGAMSFGSLSQEAHECIAQAMNSI
GAKSNSGEGGENAKRYGTINNSKIKQVASGRFGVSAAYLMSAEEIQIKISQGAKPGEGGQLPGKKAFPWVAEVRNSTPGV
SLISPPPHHDIYSIEDLSQLIFDLKKINPYAKINVKLVSSTGVGTIATGCVKAGADKVVISGYDGGTGASPRNSIRDAGL
PWEMGLAEAHQTLSLNNLRDRMILETDGKVVTGRDIAIAAMLGAEEYSFGSLALVAIGCIMTRNCHLNTCPVGIATQNPR
LRANFAGNPEHIVRLMEFMAEEVRELLAELGFRTINELVGHAELLQAKEDLPAKMRGLDFSRMLGHALPIATRHSDPFAN
PRAWKELDQFTEATLNNGSQATVHGTIKNINRTTTARMAGWIAERYGNFGLKDASVCYEYEGVAGQSFGSYATAGMEVTL
IGEANDYIGKSLSGGRLIVKPPLDAAYDIENTSIVGNVSLFGAIGGEAYFRGRAGERCGVRNSGAHFVVEGTGDHGCEYM
TGGIAVVLGTTGRNFAAGMSGGIAYVYDVAGNFENKVNREMVDLYALDETSGDEVLEELLKKHLNYTDSEKAKFILEHWQ
TEREKFVKVYPREYHHIKNVEEDLAKTGLSGEALTMTTFKKVTEVS

Sequences:

>Translated_1486_residues
MNKKAKQAMKTTLWQPDFESDACGMGFIAQIDGKASHLLVERALTMLTRMNHRGGTGAEPETGDGAGILLALPDEFFRKI
AKEHDVELPKLGDYAVGQFFLSRKENKKHQELEAIKAAVKAQGYEVLFTRTVPFNFEACGATAQGIMPSFVQVFIEKKSS
EKAVSEISNFENDLFIIRRNLEKRFDEEELYICSLSSQTVVYKGMLHAYQVKLFYPDLSDEDFKSHIALTHSRFSTNTFP
SWNRAQPFRFLAHNGEINTLRGAENWMKVNDIEMYNEENSDSAKLENCMEYFYRNGRELPESLLTMIPEAWGEQTGLSPE
LKAFYEYSTAHIAPWDGPAALVFTDGKTVGARLDRNGLRPSRYLVTKDNSIILSSESGVVDIPADEIIEKSVLGPGNMLL
VNTDEGKIIRNEEVKSYYANKYPYQEFLSAGLKKLSALTESEKTNPIPSAKMNTLWKLFGYTDEVIRTVLLPMAESANEP
TISMGFDAPLAVLSDQAQSLYNFFKQQFAQVTNPPIDAIREQIVIGTETYLGEDGNPAKITGENVRKLKLDSPVLSTADF
EKILALKEEHYHTEIISTLYDKDDLLENALNKLFYKAESLINQGTTIIVLSDRDFAENKVPMPILLALSGLYHYMLGRHN
ASKFAIIVDTAEVCEVHQFAALVGYGVSGIHPYGAYATLSDWGMGAPEQLENFRHAAEKGIVKVMSRMGISTIVGYKGAQ
LFEAIGLSKEVVDKYFTGTSTRIGGLSLAQIEDEYRLRYEKAYGHRAQDLLETGGSFQYRADEGEHHIYDPQMIYQIQNA
VRQNDFEKYKKYSQYLNDIALKTPTSLRHTWKIKSDRKSIQMSEVEPAREIVKRFKIGAMSFGSLSQEAHECIAQAMNSI
GAKSNSGEGGENAKRYGTINNSKIKQVASGRFGVSAAYLMSAEEIQIKISQGAKPGEGGQLPGKKAFPWVAEVRNSTPGV
SLISPPPHHDIYSIEDLSQLIFDLKKINPYAKINVKLVSSTGVGTIATGCVKAGADKVVISGYDGGTGASPRNSIRDAGL
PWEMGLAEAHQTLSLNNLRDRMILETDGKVVTGRDIAIAAMLGAEEYSFGSLALVAIGCIMTRNCHLNTCPVGIATQNPR
LRANFAGNPEHIVRLMEFMAEEVRELLAELGFRTINELVGHAELLQAKEDLPAKMRGLDFSRMLGHALPIATRHSDPFAN
PRAWKELDQFTEATLNNGSQATVHGTIKNINRTTTARMAGWIAERYGNFGLKDASVCYEYEGVAGQSFGSYATAGMEVTL
IGEANDYIGKSLSGGRLIVKPPLDAAYDIENTSIVGNVSLFGAIGGEAYFRGRAGERCGVRNSGAHFVVEGTGDHGCEYM
TGGIAVVLGTTGRNFAAGMSGGIAYVYDVAGNFENKVNREMVDLYALDETSGDEVLEELLKKHLNYTDSEKAKFILEHWQ
TEREKFVKVYPREYHHIKNVEEDLAKTGLSGEALTMTTFKKVTEVS
>Mature_1486_residues
MNKKAKQAMKTTLWQPDFESDACGMGFIAQIDGKASHLLVERALTMLTRMNHRGGTGAEPETGDGAGILLALPDEFFRKI
AKEHDVELPKLGDYAVGQFFLSRKENKKHQELEAIKAAVKAQGYEVLFTRTVPFNFEACGATAQGIMPSFVQVFIEKKSS
EKAVSEISNFENDLFIIRRNLEKRFDEEELYICSLSSQTVVYKGMLHAYQVKLFYPDLSDEDFKSHIALTHSRFSTNTFP
SWNRAQPFRFLAHNGEINTLRGAENWMKVNDIEMYNEENSDSAKLENCMEYFYRNGRELPESLLTMIPEAWGEQTGLSPE
LKAFYEYSTAHIAPWDGPAALVFTDGKTVGARLDRNGLRPSRYLVTKDNSIILSSESGVVDIPADEIIEKSVLGPGNMLL
VNTDEGKIIRNEEVKSYYANKYPYQEFLSAGLKKLSALTESEKTNPIPSAKMNTLWKLFGYTDEVIRTVLLPMAESANEP
TISMGFDAPLAVLSDQAQSLYNFFKQQFAQVTNPPIDAIREQIVIGTETYLGEDGNPAKITGENVRKLKLDSPVLSTADF
EKILALKEEHYHTEIISTLYDKDDLLENALNKLFYKAESLINQGTTIIVLSDRDFAENKVPMPILLALSGLYHYMLGRHN
ASKFAIIVDTAEVCEVHQFAALVGYGVSGIHPYGAYATLSDWGMGAPEQLENFRHAAEKGIVKVMSRMGISTIVGYKGAQ
LFEAIGLSKEVVDKYFTGTSTRIGGLSLAQIEDEYRLRYEKAYGHRAQDLLETGGSFQYRADEGEHHIYDPQMIYQIQNA
VRQNDFEKYKKYSQYLNDIALKTPTSLRHTWKIKSDRKSIQMSEVEPAREIVKRFKIGAMSFGSLSQEAHECIAQAMNSI
GAKSNSGEGGENAKRYGTINNSKIKQVASGRFGVSAAYLMSAEEIQIKISQGAKPGEGGQLPGKKAFPWVAEVRNSTPGV
SLISPPPHHDIYSIEDLSQLIFDLKKINPYAKINVKLVSSTGVGTIATGCVKAGADKVVISGYDGGTGASPRNSIRDAGL
PWEMGLAEAHQTLSLNNLRDRMILETDGKVVTGRDIAIAAMLGAEEYSFGSLALVAIGCIMTRNCHLNTCPVGIATQNPR
LRANFAGNPEHIVRLMEFMAEEVRELLAELGFRTINELVGHAELLQAKEDLPAKMRGLDFSRMLGHALPIATRHSDPFAN
PRAWKELDQFTEATLNNGSQATVHGTIKNINRTTTARMAGWIAERYGNFGLKDASVCYEYEGVAGQSFGSYATAGMEVTL
IGEANDYIGKSLSGGRLIVKPPLDAAYDIENTSIVGNVSLFGAIGGEAYFRGRAGERCGVRNSGAHFVVEGTGDHGCEYM
TGGIAVVLGTTGRNFAAGMSGGIAYVYDVAGNFENKVNREMVDLYALDETSGDEVLEELLKKHLNYTDSEKAKFILEHWQ
TEREKFVKVYPREYHHIKNVEEDLAKTGLSGEALTMTTFKKVTEVS

Specific function: NITROGEN METABOLISM, GLUTAMATE BIOSYNTHESIS. THE CATALYZED REACTION BRINGS TOGETHER THE NITROGEN AND CARBON METABOLISM. [C]

COG id: COG0069

COG function: function code E; Glutamate synthase domain 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI308199519, Length=1474, Percent_Identity=41.5875169606513, Blast_Score=1161, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17570289, Length=1544, Percent_Identity=42.8108808290155, Blast_Score=1194, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6320030, Length=1528, Percent_Identity=41.2958115183246, Blast_Score=1129, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574881, Length=1520, Percent_Identity=43.2894736842105, Blast_Score=1177, Evalue=0.0,
Organism=Drosophila melanogaster, GI24665539, Length=1520, Percent_Identity=43.2894736842105, Blast_Score=1177, Evalue=0.0,
Organism=Drosophila melanogaster, GI24665547, Length=380, Percent_Identity=44.2105263157895, Blast_Score=301, Evalue=2e-81,
Organism=Drosophila melanogaster, GI24665543, Length=380, Percent_Identity=44.2105263157895, Blast_Score=301, Evalue=2e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR002932
- InterPro:   IPR006982
- InterPro:   IPR002489 [H]

Pfam domain/function: PF00310 GATase_2; PF04898 Glu_syn_central; PF01645 Glu_synthase; PF01493 GXGXG [H]

EC number: =1.4.1.13 [H]

Molecular weight: Translated: 164393; Mature: 164393

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKAKQAMKTTLWQPDFESDACGMGFIAQIDGKASHLLVERALTMLTRMNHRGGTGAEP
CCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCC
ETGDGAGILLALPDEFFRKIAKEHDVELPKLGDYAVGQFFLSRKENKKHQELEAIKAAVK
CCCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
AQGYEVLFTRTVPFNFEACGATAQGIMPSFVQVFIEKKSSEKAVSEISNFENDLFIIRRN
CCCEEEEEEEECCCCCHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEH
LEKRFDEEELYICSLSSQTVVYKGMLHAYQVKLFYPDLSDEDFKSHIALTHSRFSTNTFP
HHHCCCCCCEEEEECCCCHHHHHHHHEEEEEEEEECCCCCCHHHHHHEEEECCCCCCCCC
SWNRAQPFRFLAHNGEINTLRGAENWMKVNDIEMYNEENSDSAKLENCMEYFYRNGRELP
CCCCCCCCEEEEECCCCEEECCCCCCEEECCEEECCCCCCCHHHHHHHHHHHHHCCHHHH
ESLLTMIPEAWGEQTGLSPELKAFYEYSTAHIAPWDGPAALVFTDGKTVGARLDRNGLRP
HHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEECCCCCCEEEEEECCCEECCCCCCCCCCC
SRYLVTKDNSIILSSESGVVDIPADEIIEKSVLGPGNMLLVNTDEGKIIRNEEVKSYYAN
CEEEEECCCEEEEECCCCEEECCHHHHHHHHCCCCCCEEEEECCCCCEEECHHHHHHHHC
KYPYQEFLSAGLKKLSALTESEKTNPIPSAKMNTLWKLFGYTDEVIRTVLLPMAESANEP
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCC
TISMGFDAPLAVLSDQAQSLYNFFKQQFAQVTNPPIDAIREQIVIGTETYLGEDGNPAKI
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHEEECCHHHCCCCCCCCEE
TGENVRKLKLDSPVLSTADFEKILALKEEHYHTEIISTLYDKDDLLENALNKLFYKAESL
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
INQGTTIIVLSDRDFAENKVPMPILLALSGLYHYMLGRHNASKFAIIVDTAEVCEVHQFA
HCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHH
ALVGYGVSGIHPYGAYATLSDWGMGAPEQLENFRHAAEKGIVKVMSRMGISTIVGYKGAQ
HHHHCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHH
LFEAIGLSKEVVDKYFTGTSTRIGGLSLAQIEDEYRLRYEKAYGHRAQDLLETGGSFQYR
HHHHHCCCHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEEEE
ADEGEHHIYDPQMIYQIQNAVRQNDFEKYKKYSQYLNDIALKTPTSLRHTWKIKSDRKSI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCC
QMSEVEPAREIVKRFKIGAMSFGSLSQEAHECIAQAMNSIGAKSNSGEGGENAKRYGTIN
CHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCC
NSKIKQVASGRFGVSAAYLMSAEEIQIKISQGAKPGEGGQLPGKKAFPWVAEVRNSTPGV
CHHHHHHHCCCCCCHHHHHCCHHHEEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCCCCC
SLISPPPHHDIYSIEDLSQLIFDLKKINPYAKINVKLVSSTGVGTIATGCVKAGADKVVI
EECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCHHHHHHHHCCCCEEEE
SGYDGGTGASPRNSIRDAGLPWEMGLAEAHQTLSLNNLRDRMILETDGKVVTGRDIAIAA
ECCCCCCCCCCCHHHHHCCCCHHHCHHHHHHHHHHHCCCCCEEEECCCCEEECCCEEEEE
MLGAEEYSFGSLALVAIGCIMTRNCHLNTCPVGIATQNPRLRANFAGNPEHIVRLMEFMA
EECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEECCCCCEEEECCCCHHHHHHHHHHHH
EEVRELLAELGFRTINELVGHAELLQAKEDLPAKMRGLDFSRMLGHALPIATRHSDPFAN
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHCCCCCCCCCCCCC
PRAWKELDQFTEATLNNGSQATVHGTIKNINRTTTARMAGWIAERYGNFGLKDASVCYEY
CHHHHHHHHHHHHHHCCCCEEEEEEEHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHEEEE
EGVAGQSFGSYATAGMEVTLIGEANDYIGKSLSGGRLIVKPPLDAAYDIENTSIVGNVSL
CCCCCCCCCCCEECCEEEEEEECCCHHHCCCCCCCEEEEECCCCCEECCCCCEEEECEEE
FGAIGGEAYFRGRAGERCGVRNSGAHFVVEGTGDHGCEYMTGGIAVVLGTTGRNFAAGMS
EEECCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCEEECCCEEEEEECCCCCCCCCCC
GGIAYVYDVAGNFENKVNREMVDLYALDETSGDEVLEELLKKHLNYTDSEKAKFILEHWQ
CCEEEEEEECCCCHHHHHHHHEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
TEREKFVKVYPREYHHIKNVEEDLAKTGLSGEALTMTTFKKVTEVS
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCC
>Mature Secondary Structure
MNKKAKQAMKTTLWQPDFESDACGMGFIAQIDGKASHLLVERALTMLTRMNHRGGTGAEP
CCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCC
ETGDGAGILLALPDEFFRKIAKEHDVELPKLGDYAVGQFFLSRKENKKHQELEAIKAAVK
CCCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
AQGYEVLFTRTVPFNFEACGATAQGIMPSFVQVFIEKKSSEKAVSEISNFENDLFIIRRN
CCCEEEEEEEECCCCCHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEH
LEKRFDEEELYICSLSSQTVVYKGMLHAYQVKLFYPDLSDEDFKSHIALTHSRFSTNTFP
HHHCCCCCCEEEEECCCCHHHHHHHHEEEEEEEEECCCCCCHHHHHHEEEECCCCCCCCC
SWNRAQPFRFLAHNGEINTLRGAENWMKVNDIEMYNEENSDSAKLENCMEYFYRNGRELP
CCCCCCCCEEEEECCCCEEECCCCCCEEECCEEECCCCCCCHHHHHHHHHHHHHCCHHHH
ESLLTMIPEAWGEQTGLSPELKAFYEYSTAHIAPWDGPAALVFTDGKTVGARLDRNGLRP
HHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEECCCCCCEEEEEECCCEECCCCCCCCCCC
SRYLVTKDNSIILSSESGVVDIPADEIIEKSVLGPGNMLLVNTDEGKIIRNEEVKSYYAN
CEEEEECCCEEEEECCCCEEECCHHHHHHHHCCCCCCEEEEECCCCCEEECHHHHHHHHC
KYPYQEFLSAGLKKLSALTESEKTNPIPSAKMNTLWKLFGYTDEVIRTVLLPMAESANEP
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCC
TISMGFDAPLAVLSDQAQSLYNFFKQQFAQVTNPPIDAIREQIVIGTETYLGEDGNPAKI
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHEEECCHHHCCCCCCCCEE
TGENVRKLKLDSPVLSTADFEKILALKEEHYHTEIISTLYDKDDLLENALNKLFYKAESL
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
INQGTTIIVLSDRDFAENKVPMPILLALSGLYHYMLGRHNASKFAIIVDTAEVCEVHQFA
HCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHH
ALVGYGVSGIHPYGAYATLSDWGMGAPEQLENFRHAAEKGIVKVMSRMGISTIVGYKGAQ
HHHHCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHH
LFEAIGLSKEVVDKYFTGTSTRIGGLSLAQIEDEYRLRYEKAYGHRAQDLLETGGSFQYR
HHHHHCCCHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEEEE
ADEGEHHIYDPQMIYQIQNAVRQNDFEKYKKYSQYLNDIALKTPTSLRHTWKIKSDRKSI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCC
QMSEVEPAREIVKRFKIGAMSFGSLSQEAHECIAQAMNSIGAKSNSGEGGENAKRYGTIN
CHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCC
NSKIKQVASGRFGVSAAYLMSAEEIQIKISQGAKPGEGGQLPGKKAFPWVAEVRNSTPGV
CHHHHHHHCCCCCCHHHHHCCHHHEEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCCCCC
SLISPPPHHDIYSIEDLSQLIFDLKKINPYAKINVKLVSSTGVGTIATGCVKAGADKVVI
EECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCHHHHHHHHCCCCEEEE
SGYDGGTGASPRNSIRDAGLPWEMGLAEAHQTLSLNNLRDRMILETDGKVVTGRDIAIAA
ECCCCCCCCCCCHHHHHCCCCHHHCHHHHHHHHHHHCCCCCEEEECCCCEEECCCEEEEE
MLGAEEYSFGSLALVAIGCIMTRNCHLNTCPVGIATQNPRLRANFAGNPEHIVRLMEFMA
EECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEECCCCCEEEECCCCHHHHHHHHHHHH
EEVRELLAELGFRTINELVGHAELLQAKEDLPAKMRGLDFSRMLGHALPIATRHSDPFAN
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHCCCCCCCCCCCCC
PRAWKELDQFTEATLNNGSQATVHGTIKNINRTTTARMAGWIAERYGNFGLKDASVCYEY
CHHHHHHHHHHHHHHCCCCEEEEEEEHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHEEEE
EGVAGQSFGSYATAGMEVTLIGEANDYIGKSLSGGRLIVKPPLDAAYDIENTSIVGNVSL
CCCCCCCCCCCEECCEEEEEEECCCHHHCCCCCCCEEEEECCCCCEECCCCCEEEECEEE
FGAIGGEAYFRGRAGERCGVRNSGAHFVVEGTGDHGCEYMTGGIAVVLGTTGRNFAAGMS
EEECCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCEEECCCEEEEEECCCCCCCCCCC
GGIAYVYDVAGNFENKVNREMVDLYALDETSGDEVLEELLKKHLNYTDSEKAKFILEHWQ
CCEEEEEEECCCCHHHHHHHHEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
TEREKFVKVYPREYHHIKNVEEDLAKTGLSGEALTMTTFKKVTEVS
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2548995; 11029411 [H]