Click here to switch to the map view.

The map label for this gene is yhhC

Identifier: 15672743

GI number: 15672743

Start: 771778

End: 772476

Strand: Reverse

Name: yhhC

Synonym: L171802

Alternate gene names: 15672743

Gene position: 772476-771778 (Counterclockwise)

Preceding gene: 15672744

Following gene: 30024009

Centisome position: 32.65

GC content: 41.2

Gene sequence:

>699_bases
ATGAATATTATCACTACCGACCCTCTCTTTGGCTTTGTCCTTACCGTTCTTGTCTTTATGATTGGAGTACGAATTAATGA
AAACTTTCGTAAGCCTTGGACAAATCCACTCCTCTTTGCGACTGTCGTAATAATCCTAATTCTCTCACTAGCTCATATCC
CTTATAAAAACTATTATATCGGGGGTTCAATTATCAATGACCTTATTGGACCTAGTACCGTTGCTCTTGGAATTCCTCTC
TATAAAACTTTCCACTTGATGAAACATCACGCGCGCTCAATTGTTAGCTCAATTGCTATTGCGGCTCTAGTCAACTGTAT
TTTTACCGCCCTTTGTGCTAAGTTTTTCAGCCTTAGTAAACTCGCTTCTCTTTCAATTTTCCCTAAATCAGTAACCACTG
CAATGGCTATGGGAATTTCAGATAAAATGCATGGTGTTGAACAAATTACCGTTGTTGTAGTTGTTGCTACAGGAATCCTC
ACAAGCGTGCTGGGCGGCCCTCTCTTAAAACTCTTTAGAATTACTGACCCAGTTGCTCAAGGGATTGCCCTCGGAGGAAC
TGGACATGCTGTCGGAACCGGAACAGCGATTGAACTTGGAAAAACCCAAGGTGCAATGGCAGCTCTTAGTATCGGAGTGA
CTGGTATTATGTATGTGATATTTGCTCCAATCATTGCCAAAATCATTCTTGGCTATTAA

Upstream 100 bases:

>100_bases
ATGGATTAAAGTAAAATTTGAAGGCGATTATGTCGCTTTAAAACCAGAAACTACCGTCACTTCTTCCACTGAAGACCAAT
AATTTGGAGCATATAAAATC

Downstream 100 bases:

>100_bases
AAACTCCTATATAAATAAATAAGGTTGAACATTTAATTGTCCAACCTTATTTATTTAGCTAAATTTAATCATTTTATTTA
ACTTCTTCTTCTTTTTTTCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MNIITTDPLFGFVLTVLVFMIGVRINENFRKPWTNPLLFATVVIILILSLAHIPYKNYYIGGSIINDLIGPSTVALGIPL
YKTFHLMKHHARSIVSSIAIAALVNCIFTALCAKFFSLSKLASLSIFPKSVTTAMAMGISDKMHGVEQITVVVVVATGIL
TSVLGGPLLKLFRITDPVAQGIALGGTGHAVGTGTAIELGKTQGAMAALSIGVTGIMYVIFAPIIAKIILGY

Sequences:

>Translated_232_residues
MNIITTDPLFGFVLTVLVFMIGVRINENFRKPWTNPLLFATVVIILILSLAHIPYKNYYIGGSIINDLIGPSTVALGIPL
YKTFHLMKHHARSIVSSIAIAALVNCIFTALCAKFFSLSKLASLSIFPKSVTTAMAMGISDKMHGVEQITVVVVVATGIL
TSVLGGPLLKLFRITDPVAQGIALGGTGHAVGTGTAIELGKTQGAMAALSIGVTGIMYVIFAPIIAKIILGY
>Mature_232_residues
MNIITTDPLFGFVLTVLVFMIGVRINENFRKPWTNPLLFATVVIILILSLAHIPYKNYYIGGSIINDLIGPSTVALGIPL
YKTFHLMKHHARSIVSSIAIAALVNCIFTALCAKFFSLSKLASLSIFPKSVTTAMAMGISDKMHGVEQITVVVVVATGIL
TSVLGGPLLKLFRITDPVAQGIALGGTGHAVGTGTAIELGKTQGAMAALSIGVTGIMYVIFAPIIAKIILGY

Specific function: Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like proteins CidA and/or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in p

COG id: COG1346

COG function: function code M; Putative effector of murein hydrolase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidB/LrgB family. LrgB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788464, Length=218, Percent_Identity=36.697247706422, Blast_Score=135, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007300 [H]

Pfam domain/function: PF04172 LrgB [H]

EC number: NA

Molecular weight: Translated: 24556; Mature: 24556

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIITTDPLFGFVLTVLVFMIGVRINENFRKPWTNPLLFATVVIILILSLAHIPYKNYYI
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEE
GGSIINDLIGPSTVALGIPLYKTFHLMKHHARSIVSSIAIAALVNCIFTALCAKFFSLSK
CHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LASLSIFPKSVTTAMAMGISDKMHGVEQITVVVVVATGILTSVLGGPLLKLFRITDPVAQ
HHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GIALGGTGHAVGTGTAIELGKTQGAMAALSIGVTGIMYVIFAPIIAKIILGY
CEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIITTDPLFGFVLTVLVFMIGVRINENFRKPWTNPLLFATVVIILILSLAHIPYKNYYI
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEE
GGSIINDLIGPSTVALGIPLYKTFHLMKHHARSIVSSIAIAALVNCIFTALCAKFFSLSK
CHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LASLSIFPKSVTTAMAMGISDKMHGVEQITVVVVVATGILTSVLGGPLLKLFRITDPVAQ
HHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GIALGGTGHAVGTGTAIELGKTQGAMAALSIGVTGIMYVIFAPIIAKIILGY
CEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA