Click here to switch to the map view.

The map label for this gene is tra904E

Identifier: 15672619

GI number: 15672619

Start: 626561

End: 627322

Strand: Reverse

Name: tra904E

Synonym: L0461

Alternate gene names: 15672619

Gene position: 627322-626561 (Counterclockwise)

Preceding gene: 15672620

Following gene: 15672596

Centisome position: 26.52

GC content: 38.85

Gene sequence:

>762_bases
ATGCATCGTCGTCCTTCAAAACAACAAGTGGAGAGAGAAATTCTCTCAGAGAAGATAAAAGCTGTCTTTCATGAGCATAA
GGGACGCTATGGTGCGGTTAGAATTACCAAGGTACTTCATAATACTGGTATTATGACCAACACGAAACGTGTTGGGAAAC
TGATGCACTTGATGGGACTTTATGCCAAGGGAAGCCGTTATAAATATAAACATTACAACAGAAAAGGAGCTTCGCTTTCA
AGACCCAATTTAATTAATCAGATCTTTAAAGCAACAGCTCCTAATAAAGTATGGCTGGGAGACATGACCTATATCCCTAC
CAAAGAAGGCACCTTATACTTAGCCGTGAATATCGACGTTTTTTCACGTAAGATTGTAGGCTGGTCAATGTCTTCACGGA
TGCAAGATAAACTGGTGAGGGATTGCTTCTTACAAGCTTGTGGGAAAGAACATCCTCAGCCTGGCTTGATTGTCCATACT
GATCAAGGGAGTCAATATACAAGCTCTCGTTATCAATCTACTCTTCGTCAAGTCGGTGCTCAATCTAGCATGAGTCGTAA
AGGAAATCCATATGACAATGCAATGATGGAGTCTTTTTATAAGACGCTAAAGAGGGAGCTTATTAATGATGCTCATTTTG
AGACAAGAGCTGAGGCTACTCAAGAAATATTTAAATACATTGAGACCTATTACAATACAAAAAGGATGCATTCAGGTCTT
GATTACAAGTCTCCAAAAGACTTTGAAAAATATAATTCTTAA

Upstream 100 bases:

>100_bases
AGTAAAACGTTTTGAATTTCTCTTGAAACATCATGGGAAGATAAAAATTAAGCATGCAGTAAAAGTTCTTAAGGTTTCTC
GCTCAGGTTTCTATGAATAC

Downstream 100 bases:

>100_bases
ATTCTCTTAACTCCGTGTCTAGTTTTTCGTTGACTTTCCATTTCTACTTGGATAAAAAGTCTAACTTTTGGGGTGCACAT
CAACTGACGGCTTTTTTACT

Product: transposase of IS904E

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MHRRPSKQQVEREILSEKIKAVFHEHKGRYGAVRITKVLHNTGIMTNTKRVGKLMHLMGLYAKGSRYKYKHYNRKGASLS
RPNLINQIFKATAPNKVWLGDMTYIPTKEGTLYLAVNIDVFSRKIVGWSMSSRMQDKLVRDCFLQACGKEHPQPGLIVHT
DQGSQYTSSRYQSTLRQVGAQSSMSRKGNPYDNAMMESFYKTLKRELINDAHFETRAEATQEIFKYIETYYNTKRMHSGL
DYKSPKDFEKYNS

Sequences:

>Translated_253_residues
MHRRPSKQQVEREILSEKIKAVFHEHKGRYGAVRITKVLHNTGIMTNTKRVGKLMHLMGLYAKGSRYKYKHYNRKGASLS
RPNLINQIFKATAPNKVWLGDMTYIPTKEGTLYLAVNIDVFSRKIVGWSMSSRMQDKLVRDCFLQACGKEHPQPGLIVHT
DQGSQYTSSRYQSTLRQVGAQSSMSRKGNPYDNAMMESFYKTLKRELINDAHFETRAEATQEIFKYIETYYNTKRMHSGL
DYKSPKDFEKYNS
>Mature_253_residues
MHRRPSKQQVEREILSEKIKAVFHEHKGRYGAVRITKVLHNTGIMTNTKRVGKLMHLMGLYAKGSRYKYKHYNRKGASLS
RPNLINQIFKATAPNKVWLGDMTYIPTKEGTLYLAVNIDVFSRKIVGWSMSSRMQDKLVRDCFLQACGKEHPQPGLIVHT
DQGSQYTSSRYQSTLRQVGAQSSMSRKGNPYDNAMMESFYKTLKRELINDAHFETRAEATQEIFKYIETYYNTKRMHSGL
DYKSPKDFEKYNS

Specific function: Involved in the transposition of the insertion sequence

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain

Homologues:

Organism=Homo sapiens, GI310129419, Length=219, Percent_Identity=34.703196347032, Blast_Score=125, Evalue=4e-29,
Organism=Escherichia coli, GI1788405, Length=250, Percent_Identity=42.4, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1787263, Length=250, Percent_Identity=42.4, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1786753, Length=250, Percent_Identity=42.4, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1786570, Length=250, Percent_Identity=42.4, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1786490, Length=250, Percent_Identity=42.4, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1789981, Length=234, Percent_Identity=36.3247863247863, Blast_Score=152, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): T904_LACLA (P35878)

Other databases:

- EMBL:   M27276
- EMBL:   M79445
- EMBL:   D00696
- EMBL:   AE005176
- EMBL:   AE005176
- EMBL:   AE005176
- EMBL:   AE005176
- EMBL:   AE005176
- EMBL:   X68307
- PIR:   A45821
- PIR:   F86727
- RefSeq:   NP_266293.1
- RefSeq:   NP_266296.1
- RefSeq:   NP_266793.1
- RefSeq:   NP_266978.1
- RefSeq:   NP_268302.1
- ProteinModelPortal:   P35878
- SMR:   P35878
- GeneID:   1113744
- GeneID:   1113747
- GeneID:   1114257
- GeneID:   1114449
- GeneID:   1115822
- GenomeReviews:   AE005176_GR
- GenomeReviews:   AE005176_GR
- GenomeReviews:   AE005176_GR
- GenomeReviews:   AE005176_GR
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0458
- KEGG:   lla:L0459
- KEGG:   lla:L0461
- KEGG:   lla:L0462
- KEGG:   lla:L0465
- HOGENOM:   HBG757639
- OMA:   DAYEREN
- ProtClustDB:   CLSK876682
- BioCyc:   LLAC272623:L0458-MONOMER
- BioCyc:   LLAC272623:L0459-MONOMER
- BioCyc:   LLAC272623:L0461-MONOMER
- BioCyc:   LLAC272623:L0462-MONOMER
- BioCyc:   LLAC272623:L0465-MONOMER
- GO:   GO:0032196
- InterPro:   IPR001584
- InterPro:   IPR012337

Pfam domain/function: PF00665 rve; SSF53098 RNaseH_fold

EC number: NA

Molecular weight: Translated: 29394; Mature: 29394

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCHHHCCC
>Mature Secondary Structure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CCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1482189; 11337471; 1482192