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The map label for this gene is kupB

Identifier: 15672606

GI number: 15672606

Start: 611749

End: 613764

Strand: Direct

Name: kupB

Synonym: L11749

Alternate gene names: 15672606

Gene position: 611749-613764 (Clockwise)

Preceding gene: 15672605

Following gene: 15672607

Centisome position: 25.86

GC content: 37.8

Gene sequence:

>2016_bases
GTGGGTCAAGTACACTTACATAATCGGTCGTTTAATAAAGCGACATCTGCAGGGTTCCTGATTGCATTAGGGATTGTTTA
CGGTGATATCGGAACAAGTCCACTTTATGCCATGCAGGCCATTGTTCGAGGACAGGGAGGATTAGCAAATCTTTCTGAAA
GCTTTATTTTGGGGGCTGTTTCTCTTGTAATTTGGACTTTAACATTAATTACAACTGTTAAATATGTTCTGATTGCTTTG
AAAGCAGATAACCATCATGAGGGGGGAATCTTTTCACTCTTTACCCTTGTGAGACGGATGAGAAAATGGCTGATTATTCC
AGCAATGATTGGTGGGGCGACATTATTAGCGGATGGAGCATTGACTCCTGCGGTGACGGTCACGTCAGCCATCGAGGGTT
TAAGAGGAGTAACACATGTTTACTCAAATCAGACGGCAGTCATGGTAACAACTTTGATAATCCTTGCCTTTCTCTTTTTG
ATTCAGAGGTTTGGAGCAAGTTTGGTTGGTCGTTTATTTGGACCAATTATGTTTATCTGGTTTGGCTTTTTGGGTGTAAG
TGGATTGATTAATTCTTTTCTTGACTTATCAATTTTAAAAGCAATTAATCCATATTATGCGATTCACTTATTGTTTAGTC
CAGAAAATAAAGCTGGTTTCTTTATCTTGGGTTCTATTTTCTTGGTAACGACAGGGGCAGAGGCACTTTATTCTGACTTA
GGACACGTTGGGCGTGGAAATATTTATGTCAGCTGGCCATTTGTTAAGATTTGTATTATCTTATCTTACTGTGGACAAGG
AGCTTGGCTTTTAGCTCACCGTGGTGAACACATTGAAAAACTTAATCCTTTCTTTGCTGTTTTACCTGATAATATGGTTA
TTTATGTCGTTATCTTATCAACATTGGCGGCGATTATCGCCTCTCAAGCACTGATTTCGGGTTCATTTACTTTGGTGTCT
GAAGCGATTCGTTTGAAACTTTTGCCATTGTTCAAAATTTATTATCCAGGGCAAACTTTGGGACAACTTTATATCCCAGC
AGTTAACTTTGCTCTTTGGGTAACGACTTCATTCTTTGTTTTGTATTTTAAAACTTCAGAACATATGGAAGCCGCTTATA
GCTTGGCCATTACCATCACTATGTTGATGACAACAACACTTTTGACTTATTTCTTAATTCAAAAAGGAACGCCAAAAATT
GCAATTGCAATTATTTCTATCGGTCTCTTTTGTATTGAAGGCTCATTCTTTGCTGCTTCTCTTGTCCAATTTATCAACGG
AGCATATATTGTGGTTCTGATTGCCTTGGCAATTATCTTCGTGATGTTCATCTGGAACAAGTCACACAAGATTGTCATGA
AATATATCAAATCATTGAATATTAATGAGTATAAAAATCAACTTAATGCTTTGCGTCATGATGAATCTTATGATTTATAT
CAAACAAATGTGGTTTATTTAACAAGCAAAATGGACCATGAATGGATTGACCGTTCAATCTTATATTCAATCTTGGATAA
ACGACCAAAACGTGCAGAATGTTATTGGTTTGTAAATGTAAAAGTTACTGACGAGCCTTATACTTCTGAGTATAAAGTAG
ACATGATGGATACTGACTTTATTGTTCGTGTGAATCTCTATCTTGGATTCCGTATGCGTCAAGAAGTTCCGCGTTATTTA
AGAACAATTGTGACGGATTTGATGGAATCAGGACGTTTGCCACGTCAGCATCAACATTACAGTATCACTCCAGGACGTAA
AGTTGGAGATTTCCGCTTTGTCGTTGTTGAAGAAAAGCTAATGAATGCACGTCAAATGCCAGGTTTCGAGCGTTTTGTTC
TTCAAACTAAAGCACAAATCAAGAGAATTACGGCTTCCCCAATTCGTTGGTTTGGTCTTCAATTCTCGGAAGTAACTGTT
GAAACAGTTCCCTTGGTTCTTTCAGATGTACGTAATTTGGAAATTCATGAACGATTGGAACAGGTGGATGAAGCAGAAGC
TTCAGCAACTCATTAA

Upstream 100 bases:

>100_bases
CAGGGGATAATCTGCTATAATAAAGCTATTAAAAAACGAGCTACGCTTCGTTTTATTTTATTTGACTATTTTCGTTGAAG
AAAGTTGAGGAGTTACAAAA

Downstream 100 bases:

>100_bases
AGAATATAAAAAAACTTACTGACAAAATTTCTGTCAGTAAGTTTTTATTTCTGTAAGTAAAATTTTTAACGAGCAAGTCG
TTTTCTAGCGGCTTCTTTTC

Product: potassium uptake protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MGQVHLHNRSFNKATSAGFLIALGIVYGDIGTSPLYAMQAIVRGQGGLANLSESFILGAVSLVIWTLTLITTVKYVLIAL
KADNHHEGGIFSLFTLVRRMRKWLIIPAMIGGATLLADGALTPAVTVTSAIEGLRGVTHVYSNQTAVMVTTLIILAFLFL
IQRFGASLVGRLFGPIMFIWFGFLGVSGLINSFLDLSILKAINPYYAIHLLFSPENKAGFFILGSIFLVTTGAEALYSDL
GHVGRGNIYVSWPFVKICIILSYCGQGAWLLAHRGEHIEKLNPFFAVLPDNMVIYVVILSTLAAIIASQALISGSFTLVS
EAIRLKLLPLFKIYYPGQTLGQLYIPAVNFALWVTTSFFVLYFKTSEHMEAAYSLAITITMLMTTTLLTYFLIQKGTPKI
AIAIISIGLFCIEGSFFAASLVQFINGAYIVVLIALAIIFVMFIWNKSHKIVMKYIKSLNINEYKNQLNALRHDESYDLY
QTNVVYLTSKMDHEWIDRSILYSILDKRPKRAECYWFVNVKVTDEPYTSEYKVDMMDTDFIVRVNLYLGFRMRQEVPRYL
RTIVTDLMESGRLPRQHQHYSITPGRKVGDFRFVVVEEKLMNARQMPGFERFVLQTKAQIKRITASPIRWFGLQFSEVTV
ETVPLVLSDVRNLEIHERLEQVDEAEASATH

Sequences:

>Translated_671_residues
MGQVHLHNRSFNKATSAGFLIALGIVYGDIGTSPLYAMQAIVRGQGGLANLSESFILGAVSLVIWTLTLITTVKYVLIAL
KADNHHEGGIFSLFTLVRRMRKWLIIPAMIGGATLLADGALTPAVTVTSAIEGLRGVTHVYSNQTAVMVTTLIILAFLFL
IQRFGASLVGRLFGPIMFIWFGFLGVSGLINSFLDLSILKAINPYYAIHLLFSPENKAGFFILGSIFLVTTGAEALYSDL
GHVGRGNIYVSWPFVKICIILSYCGQGAWLLAHRGEHIEKLNPFFAVLPDNMVIYVVILSTLAAIIASQALISGSFTLVS
EAIRLKLLPLFKIYYPGQTLGQLYIPAVNFALWVTTSFFVLYFKTSEHMEAAYSLAITITMLMTTTLLTYFLIQKGTPKI
AIAIISIGLFCIEGSFFAASLVQFINGAYIVVLIALAIIFVMFIWNKSHKIVMKYIKSLNINEYKNQLNALRHDESYDLY
QTNVVYLTSKMDHEWIDRSILYSILDKRPKRAECYWFVNVKVTDEPYTSEYKVDMMDTDFIVRVNLYLGFRMRQEVPRYL
RTIVTDLMESGRLPRQHQHYSITPGRKVGDFRFVVVEEKLMNARQMPGFERFVLQTKAQIKRITASPIRWFGLQFSEVTV
ETVPLVLSDVRNLEIHERLEQVDEAEASATH
>Mature_670_residues
GQVHLHNRSFNKATSAGFLIALGIVYGDIGTSPLYAMQAIVRGQGGLANLSESFILGAVSLVIWTLTLITTVKYVLIALK
ADNHHEGGIFSLFTLVRRMRKWLIIPAMIGGATLLADGALTPAVTVTSAIEGLRGVTHVYSNQTAVMVTTLIILAFLFLI
QRFGASLVGRLFGPIMFIWFGFLGVSGLINSFLDLSILKAINPYYAIHLLFSPENKAGFFILGSIFLVTTGAEALYSDLG
HVGRGNIYVSWPFVKICIILSYCGQGAWLLAHRGEHIEKLNPFFAVLPDNMVIYVVILSTLAAIIASQALISGSFTLVSE
AIRLKLLPLFKIYYPGQTLGQLYIPAVNFALWVTTSFFVLYFKTSEHMEAAYSLAITITMLMTTTLLTYFLIQKGTPKIA
IAIISIGLFCIEGSFFAASLVQFINGAYIVVLIALAIIFVMFIWNKSHKIVMKYIKSLNINEYKNQLNALRHDESYDLYQ
TNVVYLTSKMDHEWIDRSILYSILDKRPKRAECYWFVNVKVTDEPYTSEYKVDMMDTDFIVRVNLYLGFRMRQEVPRYLR
TIVTDLMESGRLPRQHQHYSITPGRKVGDFRFVVVEEKLMNARQMPGFERFVLQTKAQIKRITASPIRWFGLQFSEVTVE
TVPLVLSDVRNLEIHERLEQVDEAEASATH

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=460, Percent_Identity=36.5217391304348, Blast_Score=267, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP2_LACLA (Q9CHU4)

Other databases:

- EMBL:   AE005176
- PIR:   H86702
- RefSeq:   NP_266780.1
- GeneID:   1114244
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L11749
- NMPDR:   fig|272623.1.peg.639
- HOGENOM:   HBG351154
- OMA:   HLLFSPE
- ProtClustDB:   CLSK697323
- BioCyc:   LLAC272623:L11749-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 75478; Mature: 75347

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc6301d0)-; HASH(0xd63b790)-; HASH(0xd63208c)-; HASH(0xc4efe10)-; HASH(0xd638b40)-; HASH(0xd6416dc)-; HASH(0xd6415d4)-; HASH(0xc7d4ae4)-; HASH(0xd641814)-; HASH(0xd632050)-; HASH(0xd643a3c)-; HASH(0xd638888)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQVHLHNRSFNKATSAGFLIALGIVYGDIGTSPLYAMQAIVRGQGGLANLSESFILGAV
CCEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHH
SLVIWTLTLITTVKYVLIALKADNHHEGGIFSLFTLVRRMRKWLIIPAMIGGATLLADGA
HHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHEEHHHHHCCHHEEECCC
LTPAVTVTSAIEGLRGVTHVYSNQTAVMVTTLIILAFLFLIQRFGASLVGRLFGPIMFIW
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGFLGVSGLINSFLDLSILKAINPYYAIHLLFSPENKAGFFILGSIFLVTTGAEALYSDL
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEEEEHHHHCCCHHHHHHHH
GHVGRGNIYVSWPFVKICIILSYCGQGAWLLAHRGEHIEKLNPFFAVLPDNMVIYVVILS
CCCCCCCEEEECHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCEEEECCCCHHHHHHHHH
TLAAIIASQALISGSFTLVSEAIRLKLLPLFKIYYPGQTLGQLYIPAVNFALWVTTSFFV
HHHHHHHHHHHHCCCHHHHHHHHHHHHEEHEEEECCCCHHHHEEHHHHHHHHHHHHEEEE
LYFKTSEHMEAAYSLAITITMLMTTTLLTYFLIQKGTPKIAIAIISIGLFCIEGSFFAAS
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCHHHHH
LVQFINGAYIVVLIALAIIFVMFIWNKSHKIVMKYIKSLNINEYKNQLNALRHDESYDLY
HHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEE
QTNVVYLTSKMDHEWIDRSILYSILDKRPKRAECYWFVNVKVTDEPYTSEYKVDMMDTDF
ECEEEEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCEEEEEECCCE
IVRVNLYLGFRMRQEVPRYLRTIVTDLMESGRLPRQHQHYSITPGRKVGDFRFVVVEEKL
EEEEEEHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCEEEEEEEHHH
MNARQMPGFERFVLQTKAQIKRITASPIRWFGLQFSEVTVETVPLVLSDVRNLEIHERLE
HHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHCCEEHHHHHHHHHHHHHHHCCCHHHHHHH
QVDEAEASATH
HHHHHHCCCCH
>Mature Secondary Structure 
GQVHLHNRSFNKATSAGFLIALGIVYGDIGTSPLYAMQAIVRGQGGLANLSESFILGAV
CEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHH
SLVIWTLTLITTVKYVLIALKADNHHEGGIFSLFTLVRRMRKWLIIPAMIGGATLLADGA
HHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHEEHHHHHCCHHEEECCC
LTPAVTVTSAIEGLRGVTHVYSNQTAVMVTTLIILAFLFLIQRFGASLVGRLFGPIMFIW
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGFLGVSGLINSFLDLSILKAINPYYAIHLLFSPENKAGFFILGSIFLVTTGAEALYSDL
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEEEEHHHHCCCHHHHHHHH
GHVGRGNIYVSWPFVKICIILSYCGQGAWLLAHRGEHIEKLNPFFAVLPDNMVIYVVILS
CCCCCCCEEEECHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCEEEECCCCHHHHHHHHH
TLAAIIASQALISGSFTLVSEAIRLKLLPLFKIYYPGQTLGQLYIPAVNFALWVTTSFFV
HHHHHHHHHHHHCCCHHHHHHHHHHHHEEHEEEECCCCHHHHEEHHHHHHHHHHHHEEEE
LYFKTSEHMEAAYSLAITITMLMTTTLLTYFLIQKGTPKIAIAIISIGLFCIEGSFFAAS
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCHHHHH
LVQFINGAYIVVLIALAIIFVMFIWNKSHKIVMKYIKSLNINEYKNQLNALRHDESYDLY
HHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEE
QTNVVYLTSKMDHEWIDRSILYSILDKRPKRAECYWFVNVKVTDEPYTSEYKVDMMDTDF
ECEEEEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCEEEEEECCCE
IVRVNLYLGFRMRQEVPRYLRTIVTDLMESGRLPRQHQHYSITPGRKVGDFRFVVVEEKL
EEEEEEHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCEEEEEEEHHH
MNARQMPGFERFVLQTKAQIKRITASPIRWFGLQFSEVTVETVPLVLSDVRNLEIHERLE
HHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHCCEEHHHHHHHHHHHHHHHCCCHHHHHHH
QVDEAEASATH
HHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471