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The map label for this gene is umuC

Identifier: 15672570

GI number: 15672570

Start: 580086

End: 581552

Strand: Reverse

Name: umuC

Synonym: L180104

Alternate gene names: 15672570

Gene position: 581552-580086 (Counterclockwise)

Preceding gene: 15672571

Following gene: 15672569

Centisome position: 24.58

GC content: 35.72

Gene sequence:

>1467_bases
ATGGATAAACATAAATTAAATAACTTTTTTGACTACTCACTTGAACCTCGCAGAGCTATCCTTTTTGAAGATGTCAAATC
AAATTACGCTTCTATTGAGTGCGTTCAACGAAATCTTAACCCTTTGACAACTTCTCTTTGCGTCATGAGTCGTGCAGATA
ACACTAAAGGTTTAACGCTTGCCTCTAGTCCTACTTTTAAAAAAGTCTTTGGAATGAAAAACATAAGTCGTGCCAGTGAT
TTACCCTTTATTATTGAAACAAGGAAATTCAATTTCCCACAATGGTATCGAACACATACGGATATTTACGGACAACGGAC
TGAACCAACTTTGCAGCATGTCGCTTTCATCGAATCCTGGGCAAAACGAACATGGCTTGTTCCGCCTCAAATGCAGCTCT
ATGTAGATTATAAAATCAAAGTTACTGAAATTCTAACCAATTACACATCAATTGAAGAAATTCACTCTTACTCAATTGAT
GAATCATTTTTAGATATCACAGAATCTCTTAACTTCTTCTATCCTGATATTAGAAACCGATATGAGCAAATGAATCTGAT
TACTTTAGATTTACAACGTGAGATTTTGGATAAGTTAGGGCTTTATGTAACTGTAGGGATGGGTGATAATCCTCTACTTG
CAAAACTTGCCATGGATAACTATGCCAAACATAATCAGAATATGAGAGCATTAATACGGTATGAAGATGTGCCTAGTAAA
CTCTGGACTCTTCCTAAGATGACTGACTTCTGGGGAATTGGAAAACGAACTGAGAAACGTTTGAACAAGTTAGGAATCAG
TTCTATTAAAGAGCTTACAAATGCTGACCCTCTTCTCCTTAAACAAAAATTAGGCACAATTGGACTCCAACATTTTTTCC
ATGCAAATGGAATTGATGAAAGTAATGTAAGGGAAAAATATATTCCTAAATCTTCTAGCTTCAGCAATTCTCAAATTCTA
CCTCGTGACTACCATAAACAAAAAGAAATAGAACTTGTGATTAAAGAAATGGCTGAAAACTTAGCGATAGGGCTAAGAAA
GGGAGGAAGAATGGCAAGCAATCTTTCACTTTATGTGGGTGCTGCAGCAAGCTCTGAACACTCTTCTATTAAGATTTCAC
GCAATATTGAAGCAACACAAAATACAAAGGAACTGCAAGACCTCGCAATTCTTTTATTTCGTGAAAAATATCAAGGTGGA
GCAGTAAGGCAAATAGGAATAAGTGGCAATCAACTCTCTGATAATTCGGTCAAACAACTTTCTTTATTTGAAACTGTTGA
AGAAAATCAATTCAACGAAAAGCAGGAATCCCTTCAAAAAGCCATTGACGAAATCAGAGAAAAATTCGATTTTCTATCCA
TTCAAAAAGCAAGTAGTTTATCCGAAGGTTCACGTGTGATTTATCGAAATAAACTTATTGGAGGTCATGCAGCAAGTCAA
AATAAGGAGGATAAAGATGTCAGTTGA

Upstream 100 bases:

>100_bases
ACTATTTTTTCTGATATTATCCATTGATTAATGGTTTTTTTTAGAGTATAATATCAGATAAACAGATGTTTTGTATTAAA
TATGTTACTGAAGGGGAGAG

Downstream 100 bases:

>100_bases
CCGTTCTTATAGTTCCTATGAAGTCATTCGAGCATATCAGGATAGAGGAATGATGAAATGGGGATCATTTGCGACCGGAG
AGTTAACCGAGGCCCAAAAT

Product: UmuC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MDKHKLNNFFDYSLEPRRAILFEDVKSNYASIECVQRNLNPLTTSLCVMSRADNTKGLTLASSPTFKKVFGMKNISRASD
LPFIIETRKFNFPQWYRTHTDIYGQRTEPTLQHVAFIESWAKRTWLVPPQMQLYVDYKIKVTEILTNYTSIEEIHSYSID
ESFLDITESLNFFYPDIRNRYEQMNLITLDLQREILDKLGLYVTVGMGDNPLLAKLAMDNYAKHNQNMRALIRYEDVPSK
LWTLPKMTDFWGIGKRTEKRLNKLGISSIKELTNADPLLLKQKLGTIGLQHFFHANGIDESNVREKYIPKSSSFSNSQIL
PRDYHKQKEIELVIKEMAENLAIGLRKGGRMASNLSLYVGAAASSEHSSIKISRNIEATQNTKELQDLAILLFREKYQGG
AVRQIGISGNQLSDNSVKQLSLFETVEENQFNEKQESLQKAIDEIREKFDFLSIQKASSLSEGSRVIYRNKLIGGHAASQ
NKEDKDVS

Sequences:

>Translated_488_residues
MDKHKLNNFFDYSLEPRRAILFEDVKSNYASIECVQRNLNPLTTSLCVMSRADNTKGLTLASSPTFKKVFGMKNISRASD
LPFIIETRKFNFPQWYRTHTDIYGQRTEPTLQHVAFIESWAKRTWLVPPQMQLYVDYKIKVTEILTNYTSIEEIHSYSID
ESFLDITESLNFFYPDIRNRYEQMNLITLDLQREILDKLGLYVTVGMGDNPLLAKLAMDNYAKHNQNMRALIRYEDVPSK
LWTLPKMTDFWGIGKRTEKRLNKLGISSIKELTNADPLLLKQKLGTIGLQHFFHANGIDESNVREKYIPKSSSFSNSQIL
PRDYHKQKEIELVIKEMAENLAIGLRKGGRMASNLSLYVGAAASSEHSSIKISRNIEATQNTKELQDLAILLFREKYQGG
AVRQIGISGNQLSDNSVKQLSLFETVEENQFNEKQESLQKAIDEIREKFDFLSIQKASSLSEGSRVIYRNKLIGGHAASQ
NKEDKDVS
>Mature_488_residues
MDKHKLNNFFDYSLEPRRAILFEDVKSNYASIECVQRNLNPLTTSLCVMSRADNTKGLTLASSPTFKKVFGMKNISRASD
LPFIIETRKFNFPQWYRTHTDIYGQRTEPTLQHVAFIESWAKRTWLVPPQMQLYVDYKIKVTEILTNYTSIEEIHSYSID
ESFLDITESLNFFYPDIRNRYEQMNLITLDLQREILDKLGLYVTVGMGDNPLLAKLAMDNYAKHNQNMRALIRYEDVPSK
LWTLPKMTDFWGIGKRTEKRLNKLGISSIKELTNADPLLLKQKLGTIGLQHFFHANGIDESNVREKYIPKSSSFSNSQIL
PRDYHKQKEIELVIKEMAENLAIGLRKGGRMASNLSLYVGAAASSEHSSIKISRNIEATQNTKELQDLAILLFREKYQGG
AVRQIGISGNQLSDNSVKQLSLFETVEENQFNEKQESLQKAIDEIREKFDFLSIQKASSLSEGSRVIYRNKLIGGHAASQ
NKEDKDVS

Specific function: Poorly Processive, Error-Prone DNA Polymerase Involved In Untargeted Mutagenesis. Copies Undamaged DNA At Stalled Replication Forks, Which Arise In Vivo From Mismatched Or Misaligned Primer Ends. These Misaligned Primers Can Be Extended By Poliv. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1786425, Length=216, Percent_Identity=26.3888888888889, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: 2.7.7.7 [C]

Molecular weight: Translated: 56024; Mature: 56024

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKHKLNNFFDYSLEPRRAILFEDVKSNYASIECVQRNLNPLTTSLCVMSRADNTKGLTL
CCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEE
ASSPTFKKVFGMKNISRASDLPFIIETRKFNFPQWYRTHTDIYGQRTEPTLQHVAFIESW
ECCCCHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
AKRTWLVPPQMQLYVDYKIKVTEILTNYTSIEEIHSYSIDESFLDITESLNFFYPDIRNR
HHCEECCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHH
YEQMNLITLDLQREILDKLGLYVTVGMGDNPLLAKLAMDNYAKHNQNMRALIRYEDVPSK
HHHCCEEEEHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCHH
LWTLPKMTDFWGIGKRTEKRLNKLGISSIKELTNADPLLLKQKLGTIGLQHFFHANGIDE
HHCCCCCHHHHCCCHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
SNVREKYIPKSSSFSNSQILPRDYHKQKEIELVIKEMAENLAIGLRKGGRMASNLSLYVG
CCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
AAASSEHSSIKISRNIEATQNTKELQDLAILLFREKYQGGAVRQIGISGNQLSDNSVKQL
ECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHH
SLFETVEENQFNEKQESLQKAIDEIREKFDFLSIQKASSLSEGSRVIYRNKLIGGHAASQ
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCC
NKEDKDVS
CCCCCCCC
>Mature Secondary Structure
MDKHKLNNFFDYSLEPRRAILFEDVKSNYASIECVQRNLNPLTTSLCVMSRADNTKGLTL
CCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEE
ASSPTFKKVFGMKNISRASDLPFIIETRKFNFPQWYRTHTDIYGQRTEPTLQHVAFIESW
ECCCCHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
AKRTWLVPPQMQLYVDYKIKVTEILTNYTSIEEIHSYSIDESFLDITESLNFFYPDIRNR
HHCEECCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHH
YEQMNLITLDLQREILDKLGLYVTVGMGDNPLLAKLAMDNYAKHNQNMRALIRYEDVPSK
HHHCCEEEEHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCHH
LWTLPKMTDFWGIGKRTEKRLNKLGISSIKELTNADPLLLKQKLGTIGLQHFFHANGIDE
HHCCCCCHHHHCCCHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
SNVREKYIPKSSSFSNSQILPRDYHKQKEIELVIKEMAENLAIGLRKGGRMASNLSLYVG
CCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
AAASSEHSSIKISRNIEATQNTKELQDLAILLFREKYQGGAVRQIGISGNQLSDNSVKQL
ECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHH
SLFETVEENQFNEKQESLQKAIDEIREKFDFLSIQKASSLSEGSRVIYRNKLIGGHAASQ
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCC
NKEDKDVS
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9722542; 9384377 [H]