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The map label for this gene is hslA

Identifier: 15672484

GI number: 15672484

Start: 502338

End: 502613

Strand: Direct

Name: hslA

Synonym: L102317

Alternate gene names: 15672484

Gene position: 502338-502613 (Clockwise)

Preceding gene: 15672483

Following gene: 15672490

Centisome position: 21.24

GC content: 39.49

Gene sequence:

>276_bases
ATGGCTAACAAACAAGATCTTATCGCTGAAGTTGCAGCAAAAACAGGATTGACTAAAAAAGATTCAGAAAAAGCAGTTAA
TGCTTTTGGTGAAGTTGTAACTGAATTCCTTGCAAAAGGTGAAAAAGTTCAATTGATCGGTTTTGGTACTTTCGAAACTC
GCGAACGCGCAGCTCGTGAAGGACGTAACCCACAAACTGGTGAAGCAATCAAAATCGCTGCTACAGTTGTTCCTGCATTC
AAAGCTGGTAAAGCATTGAAAGACGCAGTTAAATAA

Upstream 100 bases:

>100_bases
CGCATTAAAATGGCATTTTGACTTGCAAACTAGGCTAAGATTTGCTAAAATGAAAATTGCCTATGTTTAAGGTAAAAAAC
AAATGGAGGACATTTCTAAA

Downstream 100 bases:

>100_bases
TTATAGCTATAAAACATCAAGTATCACGCTAGTTCGTGGTACTTTTTGTTTTTTTATAAAATGAAAAAGGGGCACAAAAG
GGGCACAAAATAAAAAAACT

Product: HU like DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 91; Mature: 90

Protein sequence:

>91_residues
MANKQDLIAEVAAKTGLTKKDSEKAVNAFGEVVTEFLAKGEKVQLIGFGTFETRERAAREGRNPQTGEAIKIAATVVPAF
KAGKALKDAVK

Sequences:

>Translated_91_residues
MANKQDLIAEVAAKTGLTKKDSEKAVNAFGEVVTEFLAKGEKVQLIGFGTFETRERAAREGRNPQTGEAIKIAATVVPAF
KAGKALKDAVK
>Mature_90_residues
ANKQDLIAEVAAKTGLTKKDSEKAVNAFGEVVTEFLAKGEKVQLIGFGTFETRERAAREGRNPQTGEAIKIAATVVPAFK
AGKALKDAVK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family

Homologues:

Organism=Escherichia coli, GI1786644, Length=88, Percent_Identity=55.6818181818182, Blast_Score=94, Evalue=1e-21,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=55.0561797752809, Blast_Score=92, Evalue=8e-21,
Organism=Escherichia coli, GI1788005, Length=77, Percent_Identity=45.4545454545455, Blast_Score=70, Evalue=3e-14,
Organism=Escherichia coli, GI1787141, Length=86, Percent_Identity=39.5348837209302, Blast_Score=68, Evalue=1e-13,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): DBH_LACLA (Q9CI64)

Other databases:

- EMBL:   AE005176
- PIR:   F86687
- RefSeq:   NP_266658.1
- ProteinModelPortal:   Q9CI64
- SMR:   Q9CI64
- GeneID:   1114121
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L102317
- NMPDR:   fig|272623.1.peg.517
- HOGENOM:   HBG705085
- OMA:   NFEVRDR
- ProtClustDB:   CLSK697261
- BioCyc:   LLAC272623:L102317-MONOMER
- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992
- Gene3D:   G3DSA:4.10.520.10
- PRINTS:   PR01727
- SMART:   SM00411

Pfam domain/function: PF00216 Bac_DNA_binding; SSF47729 IHF_like_DNA_bnd

EC number: NA

Molecular weight: Translated: 9676; Mature: 9545

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANKQDLIAEVAAKTGLTKKDSEKAVNAFGEVVTEFLAKGEKVQLIGFGTFETRERAARE
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHC
GRNPQTGEAIKIAATVVPAFKAGKALKDAVK
CCCCCCCCCEEHHHHHHHHHHCCHHHHHHCC
>Mature Secondary Structure 
ANKQDLIAEVAAKTGLTKKDSEKAVNAFGEVVTEFLAKGEKVQLIGFGTFETRERAARE
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHC
GRNPQTGEAIKIAATVVPAFKAGKALKDAVK
CCCCCCCCCEEHHHHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471