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The map label for this gene is ydgC

Identifier: 15672338

GI number: 15672338

Start: 361431

End: 362810

Strand: Reverse

Name: ydgC

Synonym: L161441

Alternate gene names: 15672338

Gene position: 362810-361431 (Counterclockwise)

Preceding gene: 15672342

Following gene: 15672337

Centisome position: 15.34

GC content: 37.17

Gene sequence:

>1380_bases
TTGGAAAATCTTCAAGAGAAACATGAAGCTCAACGGGGCTTACAGAACCGACATATTCAACTTATTGCTATTGCTGGAAC
GATTGGTACCGGACTTTTTCTAGGAGCTGGGAAAACCATTCAAATGACTGGTCCAAGCGTTATCTTTGCTTATATTCTTA
TTGGGATTGCGATGTTCTTTTTCTTAAGAACAATCGGAGAAATGCTTTACAACGACCCTAGTCAGCATTCATTTTTAAAT
TTTGTCACAAAATATTCAGGCGTCAGGACAGGTTACTTCACTCAGTGGTCTTATTGGTTAGTTATTGTTTTTGTTTGTAT
CTCTGAATTGACAGCAATCGGAACTTATATTCAATTTTGGCTTCCTCAGGTTCCACTTTGGTTGATTGAAATTGTCATGC
TAGCTCTTCTTTTTGGACTTAATACTTTAAATTCTCGCTTTTTTGGTGAAACTGAATTTTGGTTTGCGATGATTAAAGTA
GCAGCAATCATTGGAATGATTGTCACTGCGATTATTTTAGTAGCTGGTAATTTTCACTATAGCACTGTTTTAAGCGGAAA
AACCGTTCATGACTCTGCTTCACTAAGCAACATTTTTGATGGCTTTCAACTCTTCCCACACGGTGCTTGGAACTTTGTTG
GTGCCTTACAAATGGTTATGTTTGCCTTTACTTCTATGGAATTTATTGGAATGACTGCGGCAGAAACAGTTAATCCTAAA
AAGAGTTTACCAAAAGCAATTAATCAAATTCCAGTACGTATTTTACTTTTCTATGTTGGAGCACTTTTGGCTATTATGGC
TATTTTCAACTGGCACTACATTCCGGCTGATAAATCTCCATTTGTTATGGTTTTTCAACTTATTGGAATCAAATGGGCAG
CGGCGCTCATTAACTTTGTTGTCCTGACTTCTGCTGCTTCAGCGCTTAATAGTTCATTATTTTCAGCAACACGAAATATG
TACTCACTTGCTCAACAGCATGACAAAGGAAGATTAACTCCTTTTACAAAACTTTCTAAGGCGGGAATTCCTATCAATGC
CCTTTATATGGCAACTGCTCTCTCGCTTTTGGCTCCTGTCCTGACTCTTATTCCTCAGATAAAAAATGCTTTCGATTTTG
CAGCCTCTTGTACGACTAATTTATTTTTAGTGGTTTACTTTATTACCCTCTACACTTATTGGCAATATCGCAAATCTGAA
GATTACAATCCTAAAGGTTTCTTGACACCAAAACCTCAAATTACCGTTCCCTTTATCGTAGCTATCTTTGCAATTGTCTT
TGCTTCTTTGTTTTTCAATGCTGATACCTTTTATCCGGCCTTGGGAGCAATTGTCTGGACAATTTTCTTTGGACTCTACT
CGCACTATAAAAAAATCTAA

Upstream 100 bases:

>100_bases
TTTAGCAAAAAAGAATATGACTCTTGATACAAATTTATTAATTTGGTATAATAATTAACACATTATTGGAATCATCTGAT
AATTTAAGGGAGGAAAACTT

Downstream 100 bases:

>100_bases
GCGAGTCATCTTTTCCTAGACAGAGTGACTTCTGAAAAACTAAATGAAAAAGCGTATAATATAATATTATGAATACAAAT
CAAAATGAAGAAAATAAGCC

Product: amino acid permease

Products: D-glycine [Cytoplasm]; D-alanine [Cytoplasm]; Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MENLQEKHEAQRGLQNRHIQLIAIAGTIGTGLFLGAGKTIQMTGPSVIFAYILIGIAMFFFLRTIGEMLYNDPSQHSFLN
FVTKYSGVRTGYFTQWSYWLVIVFVCISELTAIGTYIQFWLPQVPLWLIEIVMLALLFGLNTLNSRFFGETEFWFAMIKV
AAIIGMIVTAIILVAGNFHYSTVLSGKTVHDSASLSNIFDGFQLFPHGAWNFVGALQMVMFAFTSMEFIGMTAAETVNPK
KSLPKAINQIPVRILLFYVGALLAIMAIFNWHYIPADKSPFVMVFQLIGIKWAAALINFVVLTSAASALNSSLFSATRNM
YSLAQQHDKGRLTPFTKLSKAGIPINALYMATALSLLAPVLTLIPQIKNAFDFAASCTTNLFLVVYFITLYTYWQYRKSE
DYNPKGFLTPKPQITVPFIVAIFAIVFASLFFNADTFYPALGAIVWTIFFGLYSHYKKI

Sequences:

>Translated_459_residues
MENLQEKHEAQRGLQNRHIQLIAIAGTIGTGLFLGAGKTIQMTGPSVIFAYILIGIAMFFFLRTIGEMLYNDPSQHSFLN
FVTKYSGVRTGYFTQWSYWLVIVFVCISELTAIGTYIQFWLPQVPLWLIEIVMLALLFGLNTLNSRFFGETEFWFAMIKV
AAIIGMIVTAIILVAGNFHYSTVLSGKTVHDSASLSNIFDGFQLFPHGAWNFVGALQMVMFAFTSMEFIGMTAAETVNPK
KSLPKAINQIPVRILLFYVGALLAIMAIFNWHYIPADKSPFVMVFQLIGIKWAAALINFVVLTSAASALNSSLFSATRNM
YSLAQQHDKGRLTPFTKLSKAGIPINALYMATALSLLAPVLTLIPQIKNAFDFAASCTTNLFLVVYFITLYTYWQYRKSE
DYNPKGFLTPKPQITVPFIVAIFAIVFASLFFNADTFYPALGAIVWTIFFGLYSHYKKI
>Mature_459_residues
MENLQEKHEAQRGLQNRHIQLIAIAGTIGTGLFLGAGKTIQMTGPSVIFAYILIGIAMFFFLRTIGEMLYNDPSQHSFLN
FVTKYSGVRTGYFTQWSYWLVIVFVCISELTAIGTYIQFWLPQVPLWLIEIVMLALLFGLNTLNSRFFGETEFWFAMIKV
AAIIGMIVTAIILVAGNFHYSTVLSGKTVHDSASLSNIFDGFQLFPHGAWNFVGALQMVMFAFTSMEFIGMTAAETVNPK
KSLPKAINQIPVRILLFYVGALLAIMAIFNWHYIPADKSPFVMVFQLIGIKWAAALINFVVLTSAASALNSSLFSATRNM
YSLAQQHDKGRLTPFTKLSKAGIPINALYMATALSLLAPVLTLIPQIKNAFDFAASCTTNLFLVVYFITLYTYWQYRKSE
DYNPKGFLTPKPQITVPFIVAIFAIVFASLFFNADTFYPALGAIVWTIFFGLYSHYKKI

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1790653, Length=455, Percent_Identity=39.7802197802198, Blast_Score=322, Evalue=3e-89,
Organism=Escherichia coli, GI1786302, Length=420, Percent_Identity=35.9523809523809, Blast_Score=291, Evalue=6e-80,
Organism=Escherichia coli, GI1786789, Length=397, Percent_Identity=38.7909319899244, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI48994972, Length=441, Percent_Identity=38.3219954648526, Blast_Score=281, Evalue=8e-77,
Organism=Escherichia coli, GI1786602, Length=411, Percent_Identity=37.2262773722628, Blast_Score=258, Evalue=7e-70,
Organism=Escherichia coli, GI87081708, Length=371, Percent_Identity=35.3099730458221, Blast_Score=228, Evalue=5e-61,
Organism=Escherichia coli, GI87081915, Length=344, Percent_Identity=34.8837209302326, Blast_Score=214, Evalue=6e-57,
Organism=Escherichia coli, GI1788480, Length=362, Percent_Identity=34.8066298342541, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1789017, Length=400, Percent_Identity=29.5, Blast_Score=194, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6324924, Length=432, Percent_Identity=29.1666666666667, Blast_Score=169, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6324061, Length=390, Percent_Identity=29.4871794871795, Blast_Score=160, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6320772, Length=385, Percent_Identity=29.8701298701299, Blast_Score=158, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6322892, Length=358, Percent_Identity=30.4469273743017, Blast_Score=149, Evalue=8e-37,
Organism=Saccharomyces cerevisiae, GI6321053, Length=406, Percent_Identity=26.1083743842365, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6324990, Length=372, Percent_Identity=28.494623655914, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6319608, Length=385, Percent_Identity=26.4935064935065, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6324059, Length=378, Percent_Identity=29.8941798941799, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324553, Length=357, Percent_Identity=29.1316526610644, Blast_Score=136, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6319824, Length=375, Percent_Identity=26.4, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320251, Length=420, Percent_Identity=23.3333333333333, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6321629, Length=365, Percent_Identity=27.1232876712329, Blast_Score=114, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6319542, Length=374, Percent_Identity=25.4010695187166, Blast_Score=111, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6320717, Length=373, Percent_Identity=24.1286863270777, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6319543, Length=351, Percent_Identity=26.7806267806268, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6322967, Length=362, Percent_Identity=25.1381215469613, Blast_Score=93, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6320364, Length=541, Percent_Identity=23.4750462107209, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324981, Length=361, Percent_Identity=25.7617728531856, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51412; Mature: 51412

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENLQEKHEAQRGLQNRHIQLIAIAGTIGTGLFLGAGKTIQMTGPSVIFAYILIGIAMFF
CCCHHHHHHHHHCHHHCCEEEEEEECHHHHHHEECCCCEEEECCHHHHHHHHHHHHHHHH
FLRTIGEMLYNDPSQHSFLNFVTKYSGVRTGYFTQWSYWLVIVFVCISELTAIGTYIQFW
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPQVPLWLIEIVMLALLFGLNTLNSRFFGETEFWFAMIKVAAIIGMIVTAIILVAGNFHY
HCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
STVLSGKTVHDSASLSNIFDGFQLFPHGAWNFVGALQMVMFAFTSMEFIGMTAAETVNPK
HHEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCH
KSLPKAINQIPVRILLFYVGALLAIMAIFNWHYIPADKSPFVMVFQLIGIKWAAALINFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VLTSAASALNSSLFSATRNMYSLAQQHDKGRLTPFTKLSKAGIPINALYMATALSLLAPV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
LTLIPQIKNAFDFAASCTTNLFLVVYFITLYTYWQYRKSEDYNPKGFLTPKPQITVPFIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
AIFAIVFASLFFNADTFYPALGAIVWTIFFGLYSHYKKI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MENLQEKHEAQRGLQNRHIQLIAIAGTIGTGLFLGAGKTIQMTGPSVIFAYILIGIAMFF
CCCHHHHHHHHHCHHHCCEEEEEEECHHHHHHEECCCCEEEECCHHHHHHHHHHHHHHHH
FLRTIGEMLYNDPSQHSFLNFVTKYSGVRTGYFTQWSYWLVIVFVCISELTAIGTYIQFW
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPQVPLWLIEIVMLALLFGLNTLNSRFFGETEFWFAMIKVAAIIGMIVTAIILVAGNFHY
HCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
STVLSGKTVHDSASLSNIFDGFQLFPHGAWNFVGALQMVMFAFTSMEFIGMTAAETVNPK
HHEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCH
KSLPKAINQIPVRILLFYVGALLAIMAIFNWHYIPADKSPFVMVFQLIGIKWAAALINFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VLTSAASALNSSLFSATRNMYSLAQQHDKGRLTPFTKLSKAGIPINALYMATALSLLAPV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
LTLIPQIKNAFDFAASCTTNLFLVVYFITLYTYWQYRKSEDYNPKGFLTPKPQITVPFIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
AIFAIVFASLFFNADTFYPALGAIVWTIFFGLYSHYKKI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-glycine [Periplasm]; D-alanine [Periplasm]; Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-glycine [Periplasm] = Proton [Cytoplasm] + D-glycine [Cytoplasm] Proton [Periplasm] + D-alanine [Periplasm] = Proton [Cytoplasm] + D-alanine [Cytoplasm] Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cyto

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]