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The map label for this gene is optC

Identifier: 15672328

GI number: 15672328

Start: 347945

End: 348976

Strand: Direct

Name: optC

Synonym: L147936

Alternate gene names: 15672328

Gene position: 347945-348976 (Clockwise)

Preceding gene: 15672327

Following gene: 15672329

Centisome position: 14.71

GC content: 38.76

Gene sequence:

>1032_bases
ATGGAAAATTTAAATAAAGACTTCACCCTTGTTGGTTCAAAGGGTTCAGATTCAACAGAAAAAATTGCGAAACCTGCCTT
GAGTTTTTTCCAAGATGCTTGGCGTCGTTTTAAGAAAAATAAAGTAGCTTTGGTTGCCATGTGGATTATTGCGATTACAT
TGGTTTTCTCAGTAATCTCAGCATTTGTTGTACCACAATCAAAGGCAAATTACTTTGATCCAAATAAATCACAAGTTTAT
GGAAATCTTCCGCCAAAACTATCAGGTGATTTACCATTTTGGAATGGTGAATTTAAAGCACCGGGTTCTACTGAAAGAAC
AGATGTCTATAAATCACAAGATGTTCCAAGCAAAGACAAATATGTCTTCGGGACTGATAAATATGGTCGTTCATTAGCTA
AACGAACAATTGTTGGTTTGCGTATTTCATTGATTATTGCCCTTGCTGCCGCCTTGATTGACTTAGTAATCGGGGTGACC
TATGGGATTATTTCCGGCTGGATGGGTGGAAAAGTCGATATGGTCATGCAACGGATTATTGAAATCATCCAATCTGTACC
TAACTTAGTTGTAGTAACAATGCTTGCTCTACTTTTGGGACAAGGAATTTCATCAATTATTATTGCGATTGGTCTATTTG
CATGGACCGGGATGGCCAGGCAGGTACGGAACATGGTTCTCTCCTATAAGGAGCGTGACTTCGTCTTGGCCTCAAAAACT
TTAGGACAATCTACTTGGAAAATTGCAGTAAAACATTTGTTGCCAAACGTTTCAGGGGTTATTGTTGTCCAAATCATGTT
TGATATTCCAAGTATGATTATGTATGAGGCTGTTTTATCAGCGATTAACCTTGGGGTTAAACCGCCAACGTCTTCTTTGG
GGACTTTGATTAATGATGGGATTGCAAGCTTGCAATTCTATCCATTCCAATTGATTATTCCAGCAGTAGTATTGTCTGTG
CTTTCACTCACATTTATCTTCTTTGGAGATGGTTTGCGTGATGCATTTGACCCTAGAGCAAGTGAGGATTAG

Upstream 100 bases:

>100_bases
AATTGTCTATGCAGTAATCTTGATGCTATTTATCTTAGTTACAGATATTCTGACTGCAATTGTTGATCCACGAGTTCGTC
TCTAGAAAGGGTTTGTCGAA

Downstream 100 bases:

>100_bases
AAATGGCAGAAGAAAAAGTATTAGAAGTTAAAAATTTGCATGTCAATTTCCACACCTATGCTGGAGATGTTAAAGCGATT
CGTGATGTATCTTTTGATTT

Product: oligopeptide ABC trasporter permease protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MENLNKDFTLVGSKGSDSTEKIAKPALSFFQDAWRRFKKNKVALVAMWIIAITLVFSVISAFVVPQSKANYFDPNKSQVY
GNLPPKLSGDLPFWNGEFKAPGSTERTDVYKSQDVPSKDKYVFGTDKYGRSLAKRTIVGLRISLIIALAAALIDLVIGVT
YGIISGWMGGKVDMVMQRIIEIIQSVPNLVVVTMLALLLGQGISSIIIAIGLFAWTGMARQVRNMVLSYKERDFVLASKT
LGQSTWKIAVKHLLPNVSGVIVVQIMFDIPSMIMYEAVLSAINLGVKPPTSSLGTLINDGIASLQFYPFQLIIPAVVLSV
LSLTFIFFGDGLRDAFDPRASED

Sequences:

>Translated_343_residues
MENLNKDFTLVGSKGSDSTEKIAKPALSFFQDAWRRFKKNKVALVAMWIIAITLVFSVISAFVVPQSKANYFDPNKSQVY
GNLPPKLSGDLPFWNGEFKAPGSTERTDVYKSQDVPSKDKYVFGTDKYGRSLAKRTIVGLRISLIIALAAALIDLVIGVT
YGIISGWMGGKVDMVMQRIIEIIQSVPNLVVVTMLALLLGQGISSIIIAIGLFAWTGMARQVRNMVLSYKERDFVLASKT
LGQSTWKIAVKHLLPNVSGVIVVQIMFDIPSMIMYEAVLSAINLGVKPPTSSLGTLINDGIASLQFYPFQLIIPAVVLSV
LSLTFIFFGDGLRDAFDPRASED
>Mature_343_residues
MENLNKDFTLVGSKGSDSTEKIAKPALSFFQDAWRRFKKNKVALVAMWIIAITLVFSVISAFVVPQSKANYFDPNKSQVY
GNLPPKLSGDLPFWNGEFKAPGSTERTDVYKSQDVPSKDKYVFGTDKYGRSLAKRTIVGLRISLIIALAAALIDLVIGVT
YGIISGWMGGKVDMVMQRIIEIIQSVPNLVVVTMLALLLGQGISSIIIAIGLFAWTGMARQVRNMVLSYKERDFVLASKT
LGQSTWKIAVKHLLPNVSGVIVVQIMFDIPSMIMYEAVLSAINLGVKPPTSSLGTLINDGIASLQFYPFQLIIPAVVLSV
LSLTFIFFGDGLRDAFDPRASED

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787498, Length=321, Percent_Identity=36.7601246105919, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1787054, Length=310, Percent_Identity=29.3548387096774, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1789889, Length=234, Percent_Identity=32.9059829059829, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787760, Length=226, Percent_Identity=32.3008849557522, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788505, Length=331, Percent_Identity=26.8882175226586, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789964, Length=313, Percent_Identity=25.8785942492013, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787549, Length=308, Percent_Identity=22.4025974025974, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37610; Mature: 37610

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENLNKDFTLVGSKGSDSTEKIAKPALSFFQDAWRRFKKNKVALVAMWIIAITLVFSVIS
CCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AFVVPQSKANYFDPNKSQVYGNLPPKLSGDLPFWNGEFKAPGSTERTDVYKSQDVPSKDK
HHHCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCC
YVFGTDKYGRSLAKRTIVGLRISLIIALAAALIDLVIGVTYGIISGWMGGKVDMVMQRII
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
EIIQSVPNLVVVTMLALLLGQGISSIIIAIGLFAWTGMARQVRNMVLSYKERDFVLASKT
HHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHH
LGQSTWKIAVKHLLPNVSGVIVVQIMFDIPSMIMYEAVLSAINLGVKPPTSSLGTLINDG
HCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
IASLQFYPFQLIIPAVVLSVLSLTFIFFGDGLRDAFDPRASED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
>Mature Secondary Structure
MENLNKDFTLVGSKGSDSTEKIAKPALSFFQDAWRRFKKNKVALVAMWIIAITLVFSVIS
CCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AFVVPQSKANYFDPNKSQVYGNLPPKLSGDLPFWNGEFKAPGSTERTDVYKSQDVPSKDK
HHHCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCC
YVFGTDKYGRSLAKRTIVGLRISLIIALAAALIDLVIGVTYGIISGWMGGKVDMVMQRII
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
EIIQSVPNLVVVTMLALLLGQGISSIIIAIGLFAWTGMARQVRNMVLSYKERDFVLASKT
HHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHH
LGQSTWKIAVKHLLPNVSGVIVVQIMFDIPSMIMYEAVLSAINLGVKPPTSSLGTLINDG
HCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
IASLQFYPFQLIIPAVVLSVLSLTFIFFGDGLRDAFDPRASED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377; 3145906 [H]