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The map label for this gene is murA1

Identifier: 15672294

GI number: 15672294

Start: 313067

End: 314332

Strand: Direct

Name: murA1

Synonym: L113067

Alternate gene names: 15672294

Gene position: 313067-314332 (Clockwise)

Preceding gene: 15672293

Following gene: 15672295

Centisome position: 13.23

GC content: 39.42

Gene sequence:

>1266_bases
ATGAAAAAAATAGTAATTAATGGTGGGAAGCGTATTTCAGGAACCATCCCAATTTCTGGCGCAAAAAATTCAGTAGTCGC
TTTGATTCCAGCAACTATCTTAGCTAACGATGTTGTAACGCTTGAAGGAGTTCCAGATATTTCTGATGTCGCAAGTTTAG
TCGAAATCATGGAAATCATGGGAGCAAAAATTGAACGAAATCTTGAAGAAGGACGACTTGTGATTGATACACGCAGTGTT
GTTTCTCGTCCCCTTCCTTATGGAAAAATCAACTCTTTACGTGCTTCTTATTATTTCAATGGTGCACTTTTGGGACGTTT
TGGTCAGGCAACAGTAGGCTTGCCTGGTGGCTGTGATTTAGGCCCTCGTCCAACGGATTTGCATGATAAAGCCTTTAAAG
CTCTAGGGGCTAAGAAGATTCAAGAAGAAGAAGCTGAGCACTTAGAAGTGATTGGTGATTCATTAGTTGGAACAACCATT
TATATGGATGTTGTTTCTGTTGGGGCAACTATTAATACTATGCTTGCTGCTAGTCGTGCAAAAGGTTTAACTATCATTGA
AAATGCTGCCCGTGAACCTGAGATTATTGATGTGGCGACACTTATAAATAATATGGGCGCGCAAGTTCGAGGAGCTGGAA
CTGACATTATCCGCATTACTGGAGTGGATGAAATGCACGGTGCTCAACATACGGTGATTCCTGACCGTATTGAAGCGGGA
ACTTATCTTGCCTTAGCTGCTGCTATGGGAGATGGTGTCATCATTGAAAATGTTATTTATGAACACTTGGAATCTTTCAT
TGCTAAACTTGAAGAAATGGGTGTAGGTTTGACCATTCGTGAAGATAGTATTGAAGTTCATAAATCAGAAAATCTAAAAT
CAGTCAATATTACTTCTGTTCCTTACCCAGGGTTTGCGACGGATTTGCAACAACCAATTACACCACTTTTATTGAAAGCA
AAAGGTCGTGGTTCAATTGTTGATACGATTTATCAAAAACGTGTCAATCATGTCCCTGAATTAGCTCGTATGGGTGCTAA
TATTTCTGTTTTAGATGATCGAATTATTTATGACGCTCCTAATGAATTAACTGGTAGTTGTGTTCAAGCAACTGACTTAC
GTGCTGGTGCGGCTTTGGTTACTGCTGGAATTATTGCCAGTGGAACTACAAAAATCTCTAATATTGAGTTTATCCTACGG
GGTTATGACCACATTATTGAAAAATTGACTGCTGTTGGTGTAGATATTCAATTGATTGAAGAGTGA

Upstream 100 bases:

>100_bases
GTCTATGAAAAACTACTATAAAATGTTAAAATAGAGAGCGGTTCTTAAAAATATAATTTTTTTAAGATAATAAAAATGTG
AAAAGTGATTTTGAAATAAT

Downstream 100 bases:

>100_bases
CAAAAGTGATTTATTTTCGTATAGACTAATGAGAAAGGAAATAAGATGGCTGATAAATTAAAATTTGAAATCATTGAAGA
ATTGATTGTTCTCTCTGAAA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MKKIVINGGKRISGTIPISGAKNSVVALIPATILANDVVTLEGVPDISDVASLVEIMEIMGAKIERNLEEGRLVIDTRSV
VSRPLPYGKINSLRASYYFNGALLGRFGQATVGLPGGCDLGPRPTDLHDKAFKALGAKKIQEEEAEHLEVIGDSLVGTTI
YMDVVSVGATINTMLAASRAKGLTIIENAAREPEIIDVATLINNMGAQVRGAGTDIIRITGVDEMHGAQHTVIPDRIEAG
TYLALAAAMGDGVIIENVIYEHLESFIAKLEEMGVGLTIREDSIEVHKSENLKSVNITSVPYPGFATDLQQPITPLLLKA
KGRGSIVDTIYQKRVNHVPELARMGANISVLDDRIIYDAPNELTGSCVQATDLRAGAALVTAGIIASGTTKISNIEFILR
GYDHIIEKLTAVGVDIQLIEE

Sequences:

>Translated_421_residues
MKKIVINGGKRISGTIPISGAKNSVVALIPATILANDVVTLEGVPDISDVASLVEIMEIMGAKIERNLEEGRLVIDTRSV
VSRPLPYGKINSLRASYYFNGALLGRFGQATVGLPGGCDLGPRPTDLHDKAFKALGAKKIQEEEAEHLEVIGDSLVGTTI
YMDVVSVGATINTMLAASRAKGLTIIENAAREPEIIDVATLINNMGAQVRGAGTDIIRITGVDEMHGAQHTVIPDRIEAG
TYLALAAAMGDGVIIENVIYEHLESFIAKLEEMGVGLTIREDSIEVHKSENLKSVNITSVPYPGFATDLQQPITPLLLKA
KGRGSIVDTIYQKRVNHVPELARMGANISVLDDRIIYDAPNELTGSCVQATDLRAGAALVTAGIIASGTTKISNIEFILR
GYDHIIEKLTAVGVDIQLIEE
>Mature_421_residues
MKKIVINGGKRISGTIPISGAKNSVVALIPATILANDVVTLEGVPDISDVASLVEIMEIMGAKIERNLEEGRLVIDTRSV
VSRPLPYGKINSLRASYYFNGALLGRFGQATVGLPGGCDLGPRPTDLHDKAFKALGAKKIQEEEAEHLEVIGDSLVGTTI
YMDVVSVGATINTMLAASRAKGLTIIENAAREPEIIDVATLINNMGAQVRGAGTDIIRITGVDEMHGAQHTVIPDRIEAG
TYLALAAAMGDGVIIENVIYEHLESFIAKLEEMGVGLTIREDSIEVHKSENLKSVNITSVPYPGFATDLQQPITPLLLKA
KGRGSIVDTIYQKRVNHVPELARMGANISVLDDRIIYDAPNELTGSCVQATDLRAGAALVTAGIIASGTTKISNIEFILR
GYDHIIEKLTAVGVDIQLIEE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=422, Percent_Identity=42.4170616113744, Blast_Score=320, Evalue=2e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA2_LACLA (Q9CIP4)

Other databases:

- EMBL:   AE005176
- PIR:   H86663
- RefSeq:   NP_266468.1
- ProteinModelPortal:   Q9CIP4
- SMR:   Q9CIP4
- GeneID:   1113922
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L113067
- NMPDR:   fig|272623.1.peg.320
- HOGENOM:   HBG482701
- OMA:   MKKIVIN
- ProtClustDB:   PRK12830
- BioCyc:   LLAC272623:L113067-MONOMER
- BRENDA:   2.5.1.7
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44918; Mature: 44918

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: ACT_SITE 118-118

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIVINGGKRISGTIPISGAKNSVVALIPATILANDVVTLEGVPDISDVASLVEIMEIM
CCEEEEECCCEEEEEEECCCCCCCEEEEEHHHHHHCCCEEECCCCCHHHHHHHHHHHHHH
GAKIERNLEEGRLVIDTRSVVSRPLPYGKINSLRASYYFNGALLGRFGQATVGLPGGCDL
HHHHHCCHHCCEEEEEEHHHHHCCCCCCCHHCEEEEEEECCHHCCCCCCCEECCCCCCCC
GPRPTDLHDKAFKALGAKKIQEEEAEHLEVIGDSLVGTTIYMDVVSVGATINTMLAASRA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHC
KGLTIIENAAREPEIIDVATLINNMGAQVRGAGTDIIRITGVDEMHGAQHTVIPDRIEAG
CCCEEEHHCCCCCCHHHHHHHHHHCCCEEECCCCCEEEEECCHHHCCCCCCCCCCHHCCC
TYLALAAAMGDGVIIENVIYEHLESFIAKLEEMGVGLTIREDSIEVHKSENLKSVNITSV
HHEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCEEEEECC
PYPGFATDLQQPITPLLLKAKGRGSIVDTIYQKRVNHVPELARMGANISVLDDRIIYDAP
CCCCCHHHHHCCCCHHEEECCCCCCHHHHHHHHHHHCCHHHHHCCCCEEEECCEEEECCC
NELTGSCVQATDLRAGAALVTAGIIASGTTKISNIEFILRGYDHIIEKLTAVGVDIQLIE
CCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEC
E
C
>Mature Secondary Structure
MKKIVINGGKRISGTIPISGAKNSVVALIPATILANDVVTLEGVPDISDVASLVEIMEIM
CCEEEEECCCEEEEEEECCCCCCCEEEEEHHHHHHCCCEEECCCCCHHHHHHHHHHHHHH
GAKIERNLEEGRLVIDTRSVVSRPLPYGKINSLRASYYFNGALLGRFGQATVGLPGGCDL
HHHHHCCHHCCEEEEEEHHHHHCCCCCCCHHCEEEEEEECCHHCCCCCCCEECCCCCCCC
GPRPTDLHDKAFKALGAKKIQEEEAEHLEVIGDSLVGTTIYMDVVSVGATINTMLAASRA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHC
KGLTIIENAAREPEIIDVATLINNMGAQVRGAGTDIIRITGVDEMHGAQHTVIPDRIEAG
CCCEEEHHCCCCCCHHHHHHHHHHCCCEEECCCCCEEEEECCHHHCCCCCCCCCCHHCCC
TYLALAAAMGDGVIIENVIYEHLESFIAKLEEMGVGLTIREDSIEVHKSENLKSVNITSV
HHEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCEEEEECC
PYPGFATDLQQPITPLLLKAKGRGSIVDTIYQKRVNHVPELARMGANISVLDDRIIYDAP
CCCCCHHHHHCCCCHHEEECCCCCCHHHHHHHHHHHCCHHHHHCCCCEEEECCEEEECCC
NELTGSCVQATDLRAGAALVTAGIIASGTTKISNIEFILRGYDHIIEKLTAVGVDIQLIE
CCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471