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The map label for this gene is yciH

Identifier: 15672272

GI number: 15672272

Start: 289409

End: 291091

Strand: Reverse

Name: yciH

Synonym: L89418

Alternate gene names: 15672272

Gene position: 291091-289409 (Counterclockwise)

Preceding gene: 15672273

Following gene: 15672271

Centisome position: 12.31

GC content: 41.24

Gene sequence:

>1683_bases
ATGCCAAAGCAACTTAAAATAAAAGCTGATGAAGTCGCAGTTTACGCCATTGGCGGACTGGGTGAAATCGGTAAAAATAC
TTACGGCGTTGAGTATAAAGATGAAATTATCATCATTGACGCCGGAATTAAATTCCCAGAAGACGATTTATTAGGTGTTG
ACTACGTCATTCCTGATTATACTTACATCGTTGAAAATATTGATCGTATCAAAGGTCTCTTCATCACTCACGGACACGAA
GACCACATCGGAGGAATTCCATTCCTCTTGAAACAGGCCAATATTCCAATTTATGCTGGACCATTGTCACTTGCGCTCAT
TCGTGGAAAGCTCGAAGAACACGGACTTTTACGTGATGCTAAACTTTATGAAATTCATGCAGATTCAGTCATTAAATTTA
ATCATTTAAGTCTTGACTTCTTCCGCACGACTCACTCAATTCCAGAACCTTTAGGGATTGTTGTAAATACTCCTCAAGGT
AAAATTGTGGCTACTGGTGACTTCAAGTTTGACTTCACACCAGTGGGTGAACCTGCTGACCTTCACCGAATGGCTGAACT
TGGAAGCGAAGGTGTTTTACTCCTTCTTTCTGACTCAACCAATGCTGAAATTCCAACTTTTTCACATTCTGAAAAAGTCG
TTGGTGCAAGCATCATGAAAATTTTTGAACGTATTGAAGGTCGAATTATTTTCGCTTCATTTGCCTCAAATATTTTCCGT
TTGCAACAAGCCGTTGATGGAGCAGTTAAGACTGGACGCAAAATTGTCGTTTTCGGTCGTTCAATGGAAAAAGCAATCGT
GAATGGTTTGGAACTCGGTTATATCAAAGCTCCTAAAGGAACTTTCATTGAACCAAATGAAGTTAATCAATACGCTTCAC
ATGAACTTTTGATTATGTGTACAGGTTCGCAAGGTGAGCCAATGGCTGCACTTTCAAGAATTGCCAACGGAATGCACCGT
CATATTACCTTACAAATGGGCGATACGGTTGTCTTCTCATCAAATGCTATTCCTGGGAATACCCACGGTGTTAACCAATT
GATTAACAAAATCGCTGAAGCTGGTGTTGAAGTTATTTATGGTAAAATGAACAACATTCACACCTCTGGTCATGGTGGGC
AACAAGAGCAAAAACTCATGTTACGTCTCATCAAACCGAAATACTTTATGCCTGTTCACGGTGAATATCGAATGCTCAAA
ATTCACGCTGGACTTGCTCAAGATACTGGTGTCCCTAAAGAAAATTGTTTCATTCAAGAAAATGGTGACGTCCTTGCATT
AACTGCTGACAGCGCAAGATATGCCGACCATTTCCCAGCCTCTGACACTTATGTTGATGGTTCAGGAATTGGTGATGTCG
GAAATGCCGTTCTCCACGACCGTCATGAACTTTCAGAAGACGGAATTGTCCTTGCGGTTGCAACCGTTGACTTTGAAAAG
AAAACCGTTCTTGCTGGCCCTGACATGCTTTCGCGTGGATTTATCTACATGCGTGAGTCTGGTGATTTGATTCGTAGTGG
TCAACGTGTCCTTTTCAATGCCATTCGTGAAGCGATGCATGAAGAAAATGCAAATGAAGCTTCTGTGGCTCGTGCGATGC
GTGAAGCACTCTCACCATTCCTTTATAAACAAACTGAACGTTCACCACTTGTTGTTCCAATGATTATGACACCTGATGAA
TAA

Upstream 100 bases:

>100_bases
GTACCTTTAAAATTCTGTCAGTAAATATTACATTAAAAAACCGAACTGACCAACTTGTCAGTCAAAAAATAAAATAAAAA
ATCCAAAGAATAGGAGAAAC

Downstream 100 bases:

>100_bases
TATTTATTAATAAAAAAAGGCTGAATATATAATGATTCAGCTTTTTTTATTGTCCTAAAGCAACACCTTAGAAATAAGAA
TATCTAAATAAAGCTCATTC

Product: hypothetical protein

Products: NA

Alternate protein names: RNase J1 [H]

Number of amino acids: Translated: 560; Mature: 559

Protein sequence:

>560_residues
MPKQLKIKADEVAVYAIGGLGEIGKNTYGVEYKDEIIIIDAGIKFPEDDLLGVDYVIPDYTYIVENIDRIKGLFITHGHE
DHIGGIPFLLKQANIPIYAGPLSLALIRGKLEEHGLLRDAKLYEIHADSVIKFNHLSLDFFRTTHSIPEPLGIVVNTPQG
KIVATGDFKFDFTPVGEPADLHRMAELGSEGVLLLLSDSTNAEIPTFSHSEKVVGASIMKIFERIEGRIIFASFASNIFR
LQQAVDGAVKTGRKIVVFGRSMEKAIVNGLELGYIKAPKGTFIEPNEVNQYASHELLIMCTGSQGEPMAALSRIANGMHR
HITLQMGDTVVFSSNAIPGNTHGVNQLINKIAEAGVEVIYGKMNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHGEYRMLK
IHAGLAQDTGVPKENCFIQENGDVLALTADSARYADHFPASDTYVDGSGIGDVGNAVLHDRHELSEDGIVLAVATVDFEK
KTVLAGPDMLSRGFIYMRESGDLIRSGQRVLFNAIREAMHEENANEASVARAMREALSPFLYKQTERSPLVVPMIMTPDE

Sequences:

>Translated_560_residues
MPKQLKIKADEVAVYAIGGLGEIGKNTYGVEYKDEIIIIDAGIKFPEDDLLGVDYVIPDYTYIVENIDRIKGLFITHGHE
DHIGGIPFLLKQANIPIYAGPLSLALIRGKLEEHGLLRDAKLYEIHADSVIKFNHLSLDFFRTTHSIPEPLGIVVNTPQG
KIVATGDFKFDFTPVGEPADLHRMAELGSEGVLLLLSDSTNAEIPTFSHSEKVVGASIMKIFERIEGRIIFASFASNIFR
LQQAVDGAVKTGRKIVVFGRSMEKAIVNGLELGYIKAPKGTFIEPNEVNQYASHELLIMCTGSQGEPMAALSRIANGMHR
HITLQMGDTVVFSSNAIPGNTHGVNQLINKIAEAGVEVIYGKMNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHGEYRMLK
IHAGLAQDTGVPKENCFIQENGDVLALTADSARYADHFPASDTYVDGSGIGDVGNAVLHDRHELSEDGIVLAVATVDFEK
KTVLAGPDMLSRGFIYMRESGDLIRSGQRVLFNAIREAMHEENANEASVARAMREALSPFLYKQTERSPLVVPMIMTPDE
>Mature_559_residues
PKQLKIKADEVAVYAIGGLGEIGKNTYGVEYKDEIIIIDAGIKFPEDDLLGVDYVIPDYTYIVENIDRIKGLFITHGHED
HIGGIPFLLKQANIPIYAGPLSLALIRGKLEEHGLLRDAKLYEIHADSVIKFNHLSLDFFRTTHSIPEPLGIVVNTPQGK
IVATGDFKFDFTPVGEPADLHRMAELGSEGVLLLLSDSTNAEIPTFSHSEKVVGASIMKIFERIEGRIIFASFASNIFRL
QQAVDGAVKTGRKIVVFGRSMEKAIVNGLELGYIKAPKGTFIEPNEVNQYASHELLIMCTGSQGEPMAALSRIANGMHRH
ITLQMGDTVVFSSNAIPGNTHGVNQLINKIAEAGVEVIYGKMNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHGEYRMLKI
HAGLAQDTGVPKENCFIQENGDVLALTADSARYADHFPASDTYVDGSGIGDVGNAVLHDRHELSEDGIVLAVATVDFEKK
TVLAGPDMLSRGFIYMRESGDLIRSGQRVLFNAIREAMHEENANEASVARAMREALSPFLYKQTERSPLVVPMIMTPDE

Specific function: Cleaves the 5'-leader sequence of certain mRNAs. May play a role in maturation and stability of specific mRNAs. Is also required for the maturation of the 16S rRNA. Acts preferentially on 16S rRNA precursors after association of the 30S and 50S ribosomal

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR004613
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 61516; Mature: 61385

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS01292 UPF0036

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKQLKIKADEVAVYAIGGLGEIGKNTYGVEYKDEIIIIDAGIKFPEDDLLGVDYVIPDY
CCCCEEEEECCEEEEEECCCCCCCCCCCCCEECCCEEEEECCCCCCCCCCCCCEEECCCH
TYIVENIDRIKGLFITHGHEDHIGGIPFLLKQANIPIYAGPLSLALIRGKLEEHGLLRDA
HHHHHHHHHHCEEEEECCCCCCCCCCCCEEEECCCCEEECHHHEEHHHHHHHHCCCCCCC
KLYEIHADSVIKFNHLSLDFFRTTHSIPEPLGIVVNTPQGKIVATGDFKFDFTPVGEPAD
EEEEEECCCEEEEECEEEEEEHHHCCCCCCCEEEEECCCCCEEEECCEEEEECCCCCCHH
LHRMAELGSEGVLLLLSDSTNAEIPTFSHSEKVVGASIMKIFERIEGRIIFASFASNIFR
HHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEHHHHHHHH
LQQAVDGAVKTGRKIVVFGRSMEKAIVNGLELGYIKAPKGTFIEPNEVNQYASHELLIMC
HHHHHHHHHHCCCEEEEECCCHHHHHHCCCEEEEEECCCCCCCCCHHHHHHCCCEEEEEE
TGSQGEPMAALSRIANGMHRHITLQMGDTVVFSSNAIPGNTHGVNQLINKIAEAGVEVIY
ECCCCCHHHHHHHHHCCCEEEEEEEECCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEE
GKMNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHGEYRMLKIHAGLAQDTGVPKENCFIQE
ECCCCEEECCCCCCHHHHHHHHHHCCCEEEECCCCEEEEEEECCCHHCCCCCCCCEEEEC
NGDVLALTADSARYADHFPASDTYVDGSGIGDVGNAVLHDRHELSEDGIVLAVATVDFEK
CCCEEEEEECCCCCCCCCCCCCCEECCCCCCCHHHHHHHCHHHCCCCCEEEEEEEECCCC
KTVLAGPDMLSRGFIYMRESGDLIRSGQRVLFNAIREAMHEENANEASVARAMREALSPF
CEEEECCCHHHCCEEEEECCCCHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHH
LYKQTERSPLVVPMIMTPDE
HHHCCCCCCEEEEEEECCCC
>Mature Secondary Structure 
PKQLKIKADEVAVYAIGGLGEIGKNTYGVEYKDEIIIIDAGIKFPEDDLLGVDYVIPDY
CCCEEEEECCEEEEEECCCCCCCCCCCCCEECCCEEEEECCCCCCCCCCCCCEEECCCH
TYIVENIDRIKGLFITHGHEDHIGGIPFLLKQANIPIYAGPLSLALIRGKLEEHGLLRDA
HHHHHHHHHHCEEEEECCCCCCCCCCCCEEEECCCCEEECHHHEEHHHHHHHHCCCCCCC
KLYEIHADSVIKFNHLSLDFFRTTHSIPEPLGIVVNTPQGKIVATGDFKFDFTPVGEPAD
EEEEEECCCEEEEECEEEEEEHHHCCCCCCCEEEEECCCCCEEEECCEEEEECCCCCCHH
LHRMAELGSEGVLLLLSDSTNAEIPTFSHSEKVVGASIMKIFERIEGRIIFASFASNIFR
HHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEHHHHHHHH
LQQAVDGAVKTGRKIVVFGRSMEKAIVNGLELGYIKAPKGTFIEPNEVNQYASHELLIMC
HHHHHHHHHHCCCEEEEECCCHHHHHHCCCEEEEEECCCCCCCCCHHHHHHCCCEEEEEE
TGSQGEPMAALSRIANGMHRHITLQMGDTVVFSSNAIPGNTHGVNQLINKIAEAGVEVIY
ECCCCCHHHHHHHHHCCCEEEEEEEECCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEE
GKMNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHGEYRMLKIHAGLAQDTGVPKENCFIQE
ECCCCEEECCCCCCHHHHHHHHHHCCCEEEECCCCEEEEEEECCCHHCCCCCCCCEEEEC
NGDVLALTADSARYADHFPASDTYVDGSGIGDVGNAVLHDRHELSEDGIVLAVATVDFEK
CCCEEEEEECCCCCCCCCCCCCCEECCCCCCCHHHHHHHCHHHCCCCCEEEEEEEECCCC
KTVLAGPDMLSRGFIYMRESGDLIRSGQRVLFNAIREAMHEENANEASVARAMREALSPF
CEEEECCCHHHCCEEEEECCCCHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHH
LYKQTERSPLVVPMIMTPDE
HHHCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377 [H]