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The map label for this gene is yciA

Identifier: 15672264

GI number: 15672264

Start: 280180

End: 281334

Strand: Direct

Name: yciA

Synonym: L80177

Alternate gene names: 15672264

Gene position: 280180-281334 (Clockwise)

Preceding gene: 15672263

Following gene: 15672265

Centisome position: 11.84

GC content: 37.14

Gene sequence:

>1155_bases
ATGATAAATTTAATCGAAATCAGACGGCAGCTTCACCAAATTCCTGAAATTGGTCTTGAAGAATACGAAACTCAAAAGTA
TTTACTAGCCATTATTCAAGAACTGACTCAAAATAAACCATTTATACAAGTAAGAACATGGCAAACCGGTATTCTAGTTT
ATCTAGCAGGAAGTCAGAGTCAAAAGACAATTGGTTGGCGAACAGATATTGACGGTCTGCCTATTGAGGAATTAACTGAT
TTACCTTATGCTAGTAAAAATGGACGAATGCACGCTTGTGGACATGATATTCACATGACCGTTGCTCTTGGTTTATTGGA
AAAAATGAGTGAAAGCCAACCAAGAGATAATCTCCTCTTTCTCTTTCAACCTGCTGAAGAAAATGAAGCGGGCGGAAAAT
TAATGTATGATGCTAGAGCATTTGAAAATTGGCTTCCTGATGAATTTTATGGATTACATGTCAGACCAGATTTAAAAGTA
GGTGATATCGCTACGAATCAGCATACACTTTTTGCAGGGACTTGTGAAGTTGAATTATCCTTTATTGGAACAGGAGGACA
TGCTGCTTTTCCCCACACAGCAAATGATGCTTTGGTAGCAGCCGCTTATTTTATCACTCAGGTTCAGACGATTGTAAGCC
GTAATGTGGATCCGTTAGCTTCAGCAGTGGTTACATTTGGAAAAATGGAGGCTGGGACAACGAATAATATTATCGCTGAA
CGTGCTTTTTTACATGGAACTATCCGGAGTCTGACCCAAGAAGTCAATGAATTGACTCAAAAACGTTTAAGAGAACTTGC
AAATGGAATCGCGCAATCTTTTAACATGGAAATTGAGCTTAAACTTAAACAAGGCGGCTATCTTCCAGTTGAAAATCATC
CTAAACTTGCTAAAGAACTGATGGAATTTTTCAAAAAAGAAACTAAGGCTAATCTTATTGACATCGCTCCAGCCATGACT
GGTGAAGATTTTGGTTACCTTTTGAGCAAAATTCCTGGAGTCATGTTCTGGTTAGGAATTGATAGTGATGCTCCCCTTCA
TTCACAAAAAATGAATCCAGACGAGCATGTTCTCAATTTTTCTGTTGATACAATTAGCCAATTTTTACAATTTAAAGTTA
ATAGGTTATCAGAAGGTGAAAAAACAATAAATTAA

Upstream 100 bases:

>100_bases
TCTTAGCAAAAGTTTTTTTGCTAAAAAGAGCAATATACAGCCAAAAAAGAGTAAAATAAATAAAAAAGATTGAAATTTAG
CTTAGTAATGAGGAAAAAAT

Downstream 100 bases:

>100_bases
TGGCTTTAATCTTAAGAATGGATATGTTAAGATAGGAGGATAGAGTTTTTTAAATCATTCAGTAGTTAAATTGTTACAAT
TGAACTTTTTTGAAATGATA

Product: amino acid amidohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MINLIEIRRQLHQIPEIGLEEYETQKYLLAIIQELTQNKPFIQVRTWQTGILVYLAGSQSQKTIGWRTDIDGLPIEELTD
LPYASKNGRMHACGHDIHMTVALGLLEKMSESQPRDNLLFLFQPAEENEAGGKLMYDARAFENWLPDEFYGLHVRPDLKV
GDIATNQHTLFAGTCEVELSFIGTGGHAAFPHTANDALVAAAYFITQVQTIVSRNVDPLASAVVTFGKMEAGTTNNIIAE
RAFLHGTIRSLTQEVNELTQKRLRELANGIAQSFNMEIELKLKQGGYLPVENHPKLAKELMEFFKKETKANLIDIAPAMT
GEDFGYLLSKIPGVMFWLGIDSDAPLHSQKMNPDEHVLNFSVDTISQFLQFKVNRLSEGEKTIN

Sequences:

>Translated_384_residues
MINLIEIRRQLHQIPEIGLEEYETQKYLLAIIQELTQNKPFIQVRTWQTGILVYLAGSQSQKTIGWRTDIDGLPIEELTD
LPYASKNGRMHACGHDIHMTVALGLLEKMSESQPRDNLLFLFQPAEENEAGGKLMYDARAFENWLPDEFYGLHVRPDLKV
GDIATNQHTLFAGTCEVELSFIGTGGHAAFPHTANDALVAAAYFITQVQTIVSRNVDPLASAVVTFGKMEAGTTNNIIAE
RAFLHGTIRSLTQEVNELTQKRLRELANGIAQSFNMEIELKLKQGGYLPVENHPKLAKELMEFFKKETKANLIDIAPAMT
GEDFGYLLSKIPGVMFWLGIDSDAPLHSQKMNPDEHVLNFSVDTISQFLQFKVNRLSEGEKTIN
>Mature_384_residues
MINLIEIRRQLHQIPEIGLEEYETQKYLLAIIQELTQNKPFIQVRTWQTGILVYLAGSQSQKTIGWRTDIDGLPIEELTD
LPYASKNGRMHACGHDIHMTVALGLLEKMSESQPRDNLLFLFQPAEENEAGGKLMYDARAFENWLPDEFYGLHVRPDLKV
GDIATNQHTLFAGTCEVELSFIGTGGHAAFPHTANDALVAAAYFITQVQTIVSRNVDPLASAVVTFGKMEAGTTNNIIAE
RAFLHGTIRSLTQEVNELTQKRLRELANGIAQSFNMEIELKLKQGGYLPVENHPKLAKELMEFFKKETKANLIDIAPAMT
GEDFGYLLSKIPGVMFWLGIDSDAPLHSQKMNPDEHVLNFSVDTISQFLQFKVNRLSEGEKTIN

Specific function: Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. DapL subfamily

Homologues:

Organism=Escherichia coli, GI87081880, Length=337, Percent_Identity=27.5964391691395, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPL_LACLA (Q9CIS4)

Other databases:

- EMBL:   AE005176
- PIR:   B86660
- RefSeq:   NP_266438.1
- HSSP:   P54970
- ProteinModelPortal:   Q9CIS4
- SMR:   Q9CIS4
- GeneID:   1113892
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L80177
- NMPDR:   fig|272623.1.peg.290
- HOGENOM:   HBG708500
- OMA:   RTWQTGI
- ProtClustDB:   CLSK876719
- BioCyc:   LLAC272623:L80177-MONOMER
- HAMAP:   MF_01692
- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650
- PIRSF:   PIRSF005962
- TIGRFAMs:   TIGR01891

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20; SSF55031 Peptidase_M20_dimer

EC number: =3.5.1.47

Molecular weight: Translated: 43101; Mature: 43101

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00758 ARGE_DAPE_CPG2_1; PS00759 ARGE_DAPE_CPG2_2

Important sites: ACT_SITE 69-69 ACT_SITE 127-127

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINLIEIRRQLHQIPEIGLEEYETQKYLLAIIQELTQNKPFIQVRTWQTGILVYLAGSQS
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEEEECCCC
QKTIGWRTDIDGLPIEELTDLPYASKNGRMHACGHDIHMTVALGLLEKMSESQPRDNLLF
CCCCCCCCCCCCCCHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCEEE
LFQPAEENEAGGKLMYDARAFENWLPDEFYGLHVRPDLKVGDIATNQHTLFAGTCEVELS
EEECCCCCCCCCEEEEEHHHHHHCCCCCCEEEEECCCCCCCCEECCCEEEEEEEEEEEEE
FIGTGGHAAFPHTANDALVAAAYFITQVQTIVSRNVDPLASAVVTFGKMEAGTTNNIIAE
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHH
RAFLHGTIRSLTQEVNELTQKRLRELANGIAQSFNMEIELKLKQGGYLPVENHPKLAKEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHH
MEFFKKETKANLIDIAPAMTGEDFGYLLSKIPGVMFWLGIDSDAPLHSQKMNPDEHVLNF
HHHHHHHHCCCEEEECCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHEEEE
SVDTISQFLQFKVNRLSEGEKTIN
EHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MINLIEIRRQLHQIPEIGLEEYETQKYLLAIIQELTQNKPFIQVRTWQTGILVYLAGSQS
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEEEECCCC
QKTIGWRTDIDGLPIEELTDLPYASKNGRMHACGHDIHMTVALGLLEKMSESQPRDNLLF
CCCCCCCCCCCCCCHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCEEE
LFQPAEENEAGGKLMYDARAFENWLPDEFYGLHVRPDLKVGDIATNQHTLFAGTCEVELS
EEECCCCCCCCCEEEEEHHHHHHCCCCCCEEEEECCCCCCCCEECCCEEEEEEEEEEEEE
FIGTGGHAAFPHTANDALVAAAYFITQVQTIVSRNVDPLASAVVTFGKMEAGTTNNIIAE
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHH
RAFLHGTIRSLTQEVNELTQKRLRELANGIAQSFNMEIELKLKQGGYLPVENHPKLAKEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHH
MEFFKKETKANLIDIAPAMTGEDFGYLLSKIPGVMFWLGIDSDAPLHSQKMNPDEHVLNF
HHHHHHHHCCCEEEECCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHEEEE
SVDTISQFLQFKVNRLSEGEKTIN
EHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471