Click here to switch to the map view.

The map label for this gene is ygbD [C]

Identifier: 15668830

GI number: 15668830

Start: 576053

End: 577444

Strand: Direct

Name: ygbD [C]

Synonym: MJ0649

Alternate gene names: 15668830

Gene position: 576053-577444 (Clockwise)

Preceding gene: 15668827

Following gene: 15668831

Centisome position: 34.6

GC content: 34.63

Gene sequence:

>1392_bases
TTGGTTAATAGAAAACCAAATAACCCCAATAAAAATGGTGAGGAAATGAGAGCAATAATAATAGGAAGTGGAGCTGCTGG
TTTAACAACAGCATCAACAATCAGAAAATACAACAAAGATATGGAAATAGTAGTAATAACAAAAGAAAAGGAAATAGCTT
ATTCTCCATGTGCAATTCCCTATGTTATTGAGGGAGCAATAAAGAGCTTTGATGACATTATTATGCACACTCCAGAAGAT
TACAAAAGAGAGAGAAACATCGATATATTAACTGAAACTACCGTTATAGATGTTGATTCAAAAAATAACAAAATAAAGTG
TGTAGATAAAGATGGAAATGAGTTTGAGATGAATTATGATTACTTAGTTTTAGCAACTGGAGCAGAGCCATTTATCCCTC
CAATTGAAGGAAAAGACTTAGATGGAGTATTTAAAGTTAGAACTATTGAGGATGGTAGGGCTATATTAAAATACATTGAA
GAAAATGGCTGTAAAAAAGTTGCTGTTGTTGGAGCTGGAGCTATTGGCTTGGAGATGGCTTATGGTTTAAAATGTAGAGG
TTTAGATGTCTTAGTTGTTGAGATGGCTCCTCAAGTGTTACCAAGATTCTTAGACCCAGATATGGCTGAGATAGTTCAAA
AATATTTAGAAAAAGAAGGAATTAAGGTTATGCTATCAAAACCATTGGAAAAGATTGTTGGAAAAGAGAAGGTTGAAGCA
GTTTATGTTGATGGTAAGTTGTATGATGTTGATATGGTTATTATGGCTACTGGTGTAAGGCCAAATATTGAGTTGGCTAA
AAAAGCTGGCTGTAAAATTGGAAAATTTGCAATAGAAGTAAATGAGAAGATGCAAACCTCTATACCAAACATCTATGCAG
TTGGAGATTGTGTTGAAGTTATTGACTTTATAACTGGAGAGAAAACACTATCTCCATTTGGAACTGCTGCTGTAAGGCAA
GGAAAAGTTGCTGGTAAAAATATAGCTGGAGTTGAAGCAAAGTTCTATCCAGTTTTAAACTCTGCTGTTAGCAAAATAGG
AGATTTAGAGATTGGAGGAACAGGTTTAACAGCATTCTCTGCCAATTTAAAGAGAATTCCAATAGTTATTGGTAGAGCTA
AGGCGTTAACAAGAGCAAGATACTATCCAGGAGGAAAAGAGATTGAGATAAAGATGATATTTAATGAAGATGGCAAAGTA
GTTGGATGTCAAATCGTTGGTGGAGAGAGAGTTGCTGAAAGAATAGATGCAATGTCTATAGCAATATTTAAAAAAGTTAG
TGCAGAGGAACTTGCAAATATGGAGTTCTGCTATGCTCCACCAGTTTCTATGGTGCATGAGCCATTATCATTAGCTGCTG
AAGATGCTTTGAAAAAGTTGAGTAATAAATAA

Upstream 100 bases:

>100_bases
ATTTCACAATTATTGTATTAGTTAGAAGTTCTATAAAAACTTTTTGGTTAAGTTCATTTTTGTGTCAAAATCATGATCAT
CAAAAAGGATAAAAAATAAT

Downstream 100 bases:

>100_bases
TTGGTGAATTTTATGAAAAGAATCTTAATTTTCTTTATATTATTTTTATTATTTTGTGGTAGTTTAAAAGCACATTTGAT
ATTTTATGATAAGGATGTTT

Product: NADH oxidase

Products: NA

Alternate protein names: NOXase [H]

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MVNRKPNNPNKNGEEMRAIIIGSGAAGLTTASTIRKYNKDMEIVVITKEKEIAYSPCAIPYVIEGAIKSFDDIIMHTPED
YKRERNIDILTETTVIDVDSKNNKIKCVDKDGNEFEMNYDYLVLATGAEPFIPPIEGKDLDGVFKVRTIEDGRAILKYIE
ENGCKKVAVVGAGAIGLEMAYGLKCRGLDVLVVEMAPQVLPRFLDPDMAEIVQKYLEKEGIKVMLSKPLEKIVGKEKVEA
VYVDGKLYDVDMVIMATGVRPNIELAKKAGCKIGKFAIEVNEKMQTSIPNIYAVGDCVEVIDFITGEKTLSPFGTAAVRQ
GKVAGKNIAGVEAKFYPVLNSAVSKIGDLEIGGTGLTAFSANLKRIPIVIGRAKALTRARYYPGGKEIEIKMIFNEDGKV
VGCQIVGGERVAERIDAMSIAIFKKVSAEELANMEFCYAPPVSMVHEPLSLAAEDALKKLSNK

Sequences:

>Translated_463_residues
MVNRKPNNPNKNGEEMRAIIIGSGAAGLTTASTIRKYNKDMEIVVITKEKEIAYSPCAIPYVIEGAIKSFDDIIMHTPED
YKRERNIDILTETTVIDVDSKNNKIKCVDKDGNEFEMNYDYLVLATGAEPFIPPIEGKDLDGVFKVRTIEDGRAILKYIE
ENGCKKVAVVGAGAIGLEMAYGLKCRGLDVLVVEMAPQVLPRFLDPDMAEIVQKYLEKEGIKVMLSKPLEKIVGKEKVEA
VYVDGKLYDVDMVIMATGVRPNIELAKKAGCKIGKFAIEVNEKMQTSIPNIYAVGDCVEVIDFITGEKTLSPFGTAAVRQ
GKVAGKNIAGVEAKFYPVLNSAVSKIGDLEIGGTGLTAFSANLKRIPIVIGRAKALTRARYYPGGKEIEIKMIFNEDGKV
VGCQIVGGERVAERIDAMSIAIFKKVSAEELANMEFCYAPPVSMVHEPLSLAAEDALKKLSNK
>Mature_463_residues
MVNRKPNNPNKNGEEMRAIIIGSGAAGLTTASTIRKYNKDMEIVVITKEKEIAYSPCAIPYVIEGAIKSFDDIIMHTPED
YKRERNIDILTETTVIDVDSKNNKIKCVDKDGNEFEMNYDYLVLATGAEPFIPPIEGKDLDGVFKVRTIEDGRAILKYIE
ENGCKKVAVVGAGAIGLEMAYGLKCRGLDVLVVEMAPQVLPRFLDPDMAEIVQKYLEKEGIKVMLSKPLEKIVGKEKVEA
VYVDGKLYDVDMVIMATGVRPNIELAKKAGCKIGKFAIEVNEKMQTSIPNIYAVGDCVEVIDFITGEKTLSPFGTAAVRQ
GKVAGKNIAGVEAKFYPVLNSAVSKIGDLEIGGTGLTAFSANLKRIPIVIGRAKALTRARYYPGGKEIEIKMIFNEDGKV
VGCQIVGGERVAERIDAMSIAIFKKVSAEELANMEFCYAPPVSMVHEPLSLAAEDALKKLSNK

Specific function: Catalyzes the four-electron reduction of molecular oxygen to water [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI65787454, Length=334, Percent_Identity=29.940119760479, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI21389617, Length=334, Percent_Identity=29.940119760479, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI226437568, Length=334, Percent_Identity=29.940119760479, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI4757732, Length=269, Percent_Identity=28.996282527881, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI22202629, Length=269, Percent_Identity=28.996282527881, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI291045266, Length=296, Percent_Identity=30.0675675675676, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI291045268, Length=283, Percent_Identity=30.0353356890459, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1789065, Length=317, Percent_Identity=30.2839116719243, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1789765, Length=401, Percent_Identity=29.6758104738155, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1788892, Length=286, Percent_Identity=25.1748251748252, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87082354, Length=413, Percent_Identity=26.3922518159806, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786307, Length=352, Percent_Identity=28.6931818181818, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081717, Length=306, Percent_Identity=25.4901960784314, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17559934, Length=284, Percent_Identity=27.8169014084507, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32565766, Length=206, Percent_Identity=26.6990291262136, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6325166, Length=367, Percent_Identity=26.9754768392371, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639257, Length=335, Percent_Identity=25.0746268656716, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281359715, Length=335, Percent_Identity=25.0746268656716, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281359713, Length=335, Percent_Identity=25.0746268656716, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24639250, Length=335, Percent_Identity=25.0746268656716, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI18543267, Length=335, Percent_Identity=25.0746268656716, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24639252, Length=335, Percent_Identity=25.0746268656716, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24585130, Length=344, Percent_Identity=23.546511627907, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 50600; Mature: 50600

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNRKPNNPNKNGEEMRAIIIGSGAAGLTTASTIRKYNKDMEIVVITKEKEIAYSPCAIP
CCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCH
YVIEGAIKSFDDIIMHTPEDYKRERNIDILTETTVIDVDSKNNKIKCVDKDGNEFEMNYD
HHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEEEEEEEECCCCCEEEEEECCCCEEEEECC
YLVLATGAEPFIPPIEGKDLDGVFKVRTIEDGRAILKYIEENGCKKVAVVGAGAIGLEMA
EEEEECCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCEEEEEEECCHHHHHHH
YGLKCRGLDVLVVEMAPQVLPRFLDPDMAEIVQKYLEKEGIKVMLSKPLEKIVGKEKVEA
CCCEECCCCEEEEHHCHHHHHHHCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHCCCEEEE
VYVDGKLYDVDMVIMATGVRPNIELAKKAGCKIGKFAIEVNEKMQTSIPNIYAVGDCVEV
EEECCEEEEEEEEEEEECCCCCHHHHHHCCCEEEEEEEEECCHHHHCCCCEEEHHHHHHH
IDFITGEKTLSPFGTAAVRQGKVAGKNIAGVEAKFYPVLNSAVSKIGDLEIGGTGLTAFS
HHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHCCEEECCCCEEEEC
ANLKRIPIVIGRAKALTRARYYPGGKEIEIKMIFNEDGKVVGCQIVGGERVAERIDAMSI
CCCCEEEEEEECHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEEEECCHHHHHHHHHHHH
AIFKKVSAEELANMEFCYAPPVSMVHEPLSLAAEDALKKLSNK
HHHHHCCHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVNRKPNNPNKNGEEMRAIIIGSGAAGLTTASTIRKYNKDMEIVVITKEKEIAYSPCAIP
CCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCH
YVIEGAIKSFDDIIMHTPEDYKRERNIDILTETTVIDVDSKNNKIKCVDKDGNEFEMNYD
HHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEEEEEEEECCCCCEEEEEECCCCEEEEECC
YLVLATGAEPFIPPIEGKDLDGVFKVRTIEDGRAILKYIEENGCKKVAVVGAGAIGLEMA
EEEEECCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCEEEEEEECCHHHHHHH
YGLKCRGLDVLVVEMAPQVLPRFLDPDMAEIVQKYLEKEGIKVMLSKPLEKIVGKEKVEA
CCCEECCCCEEEEHHCHHHHHHHCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHCCCEEEE
VYVDGKLYDVDMVIMATGVRPNIELAKKAGCKIGKFAIEVNEKMQTSIPNIYAVGDCVEV
EEECCEEEEEEEEEEEECCCCCHHHHHHCCCEEEEEEEEECCHHHHCCCCEEEHHHHHHH
IDFITGEKTLSPFGTAAVRQGKVAGKNIAGVEAKFYPVLNSAVSKIGDLEIGGTGLTAFS
HHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHCCEEECCCCEEEEC
ANLKRIPIVIGRAKALTRARYYPGGKEIEIKMIFNEDGKVVGCQIVGGERVAERIDAMSI
CCCCEEEEEEECHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEEEECCHHHHHHHHHHHH
AIFKKVSAEELANMEFCYAPPVSMVHEPLSLAAEDALKKLSNK
HHHHHCCHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]