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The map label for this gene is atpD

Identifier: 15668796

GI number: 15668796

Start: 545694

End: 546344

Strand: Reverse

Name: atpD

Synonym: MJ0615

Alternate gene names: 15668796

Gene position: 546344-545694 (Counterclockwise)

Preceding gene: 15668797

Following gene: 15668795

Centisome position: 32.81

GC content: 33.18

Gene sequence:

>651_bases
ATGCAGAGAGTGAATCCAACAAGAATGGAGTTATTAAAATTAAAAAATAAAATTAAATTGGCAGAAAAAGGGCATAAATT
GCTTAAGCAGAAAAGAGATGCTTTAATCATGGAATTCTTCCAAATTATAGAGCAAGCTTCAGATTTGAGGGATAAGGTTG
AGGCAAAGTTAGCTGAGGCATATAAAGATTTGATAATGGCTCAGACAGTTATGGGAACTTTAGCAGTTAAAGAGGCAGCA
TTAGCAGCTAAGAATGATAAATTAGAAGTTGATATGGATACAAAGAATATTATGGGTGTTACTGTTCCTACTTTTGAAAT
ATACAACGTTAGAAGAAAGGTTGGTGAAAGAGGCTACTCACCTTACGGAGTTAGCTCAAAATTAGATGAAGCAGCTAAGA
AATTTGAAGAAGCTTTAGAATTAATAACTGAATTGGCTGAAATAGAGACATCAATTAAACTCTTAGCTGAGGAGATTATA
ACAACAAAAAGAAGAGTTAATGCTTTAGAGTATGTTATTATCCCAAGATTAAAATCTCTCAAAAAGTATATATCAATGAG
ATTGGATGAGATGGAAAGAGAGAACTTCTTCAGGTTGAAGTTAATTAAATCGAGAATTGAGAAGAGAGAAGCCGAAGGGG
AGACAGTATAA

Upstream 100 bases:

>100_bases
ATGAAAAAGTTAAGGAAATGTTTAAATAACTATAACCATTAAATTTTTATGTTATAACGTTGCTAATAATTTTTACTTAT
AAAAGTGGAGAGGGATTTAC

Downstream 100 bases:

>100_bases
TTACAAAAATAATTTTTGATGCAACTGAAGCGTTAGCTTCGGGTTACAAATTCGAAGGATTTGTTTAACAGAAAGCTTTG
CTTTCTGGCTACAAAAACTC

Product: V-type ATP synthase subunit D

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit D

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MQRVNPTRMELLKLKNKIKLAEKGHKLLKQKRDALIMEFFQIIEQASDLRDKVEAKLAEAYKDLIMAQTVMGTLAVKEAA
LAAKNDKLEVDMDTKNIMGVTVPTFEIYNVRRKVGERGYSPYGVSSKLDEAAKKFEEALELITELAEIETSIKLLAEEII
TTKRRVNALEYVIIPRLKSLKKYISMRLDEMERENFFRLKLIKSRIEKREAEGETV

Sequences:

>Translated_216_residues
MQRVNPTRMELLKLKNKIKLAEKGHKLLKQKRDALIMEFFQIIEQASDLRDKVEAKLAEAYKDLIMAQTVMGTLAVKEAA
LAAKNDKLEVDMDTKNIMGVTVPTFEIYNVRRKVGERGYSPYGVSSKLDEAAKKFEEALELITELAEIETSIKLLAEEII
TTKRRVNALEYVIIPRLKSLKKYISMRLDEMERENFFRLKLIKSRIEKREAEGETV
>Mature_216_residues
MQRVNPTRMELLKLKNKIKLAEKGHKLLKQKRDALIMEFFQIIEQASDLRDKVEAKLAEAYKDLIMAQTVMGTLAVKEAA
LAAKNDKLEVDMDTKNIMGVTVPTFEIYNVRRKVGERGYSPYGVSSKLDEAAKKFEEALELITELAEIETSIKLLAEEII
TTKRRVNALEYVIIPRLKSLKKYISMRLDEMERENFFRLKLIKSRIEKREAEGETV

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane

COG id: COG1394

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase D subunit family

Homologues:

Organism=Homo sapiens, GI7706757, Length=227, Percent_Identity=34.8017621145374, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17553636, Length=211, Percent_Identity=35.0710900473934, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320784, Length=205, Percent_Identity=32.1951219512195, Blast_Score=97, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21355551, Length=217, Percent_Identity=36.8663594470046, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI20128937, Length=211, Percent_Identity=35.5450236966825, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI20129907, Length=211, Percent_Identity=27.4881516587678, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): VATD_METJA (Q58032)

Other databases:

- EMBL:   L77117
- PIR:   G64376
- RefSeq:   NP_247599.1
- ProteinModelPortal:   Q58032
- GeneID:   1451481
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0615
- NMPDR:   fig|243232.1.peg.636
- TIGR:   MJ0615
- HOGENOM:   HBG732046
- OMA:   EDARNST
- ProtClustDB:   PRK00373
- BioCyc:   MJAN243232:MJ_0615-MONOMER
- BRENDA:   3.6.3.14
- HAMAP:   MF_00271
- InterPro:   IPR002699
- PANTHER:   PTHR11671
- TIGRFAMs:   TIGR00309

Pfam domain/function: PF01813 ATP-synt_D

EC number: 3.6.3.14

Molecular weight: Translated: 24952; Mature: 24952

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRVNPTRMELLKLKNKIKLAEKGHKLLKQKRDALIMEFFQIIEQASDLRDKVEAKLAEA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKDLIMAQTVMGTLAVKEAALAAKNDKLEVDMDTKNIMGVTVPTFEIYNVRRKVGERGYS
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHCCCC
PYGVSSKLDEAAKKFEEALELITELAEIETSIKLLAEEIITTKRRVNALEYVIIPRLKSL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKYISMRLDEMERENFFRLKLIKSRIEKREAEGETV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQRVNPTRMELLKLKNKIKLAEKGHKLLKQKRDALIMEFFQIIEQASDLRDKVEAKLAEA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKDLIMAQTVMGTLAVKEAALAAKNDKLEVDMDTKNIMGVTVPTFEIYNVRRKVGERGYS
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHCCCC
PYGVSSKLDEAAKKFEEALELITELAEIETSIKLLAEEIITTKRRVNALEYVIIPRLKSL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKYISMRLDEMERENFFRLKLIKSRIEKREAEGETV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087