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The map label for this gene is hycD [C]

Identifier: 15668699

GI number: 15668699

Start: 460465

End: 461352

Strand: Reverse

Name: hycD [C]

Synonym: MJ0520

Alternate gene names: 15668699

Gene position: 461352-460465 (Counterclockwise)

Preceding gene: 15668700

Following gene: 15668698

Centisome position: 27.71

GC content: 34.8

Gene sequence:

>888_bases
GTGATGCTTATGGATACTTCACTTATCGGAGCTATAAACTTAACAATCCATGCATTTCTTGTTGGTTCTCTGTTACTTGG
ATTACATAGAAAAATAATGGCAAGGATTCAAGGAAGACCAGGACCTCCAATAATCCAATATCTATTGCATACACTAAAAT
TCTATGTAAAGGAAATAACTTTCCCAATAACTGCTGGAAATCCTCTCTATATATTTGTAGCTTTATTGGATATTGCTATT
TGGTTAGCTGCATTAATTATAGCTATTGATTTCAAGTCATCCCTCCTTATAATTATAGGAATCTATGTATTGCAAAAAAT
AGTGGAGCATGGTTGTGGTTTGTCATCTGGGTCTCCTTATGGAAAGATAGGAGGGGTTAGAAGTGTCTTTTCAGCAGCTG
CAGAAGTGCCATTATTTGCAGTTGTTGCTGCCATATACTTAACAACACATTCAGTTTTAATTTCAGATATATTGAGTTAT
CAAGAAATACACGGCAGTTTATTGTTTAAAATGCCAATTTGTGCATTCGCATTCTTTATATTGCTTGTTTCAAAAGCTCC
AAACAGTCCATTTGGGATAGTTAAGGGTAAAGATATTGTTAGCGGATATATGACAGAGCATTATGGTTTATTAGGGGCTA
TAATCTACATTGCAGAGGCAATAGCATACTTTGTATTGCTCTGGCTCTTTATAGCTGTATTTATTGGTCCTTTAGTAATA
AACAGCCCTGTATTAACATTGGCTGTAATGGTTGTAATGACAGTGATTTTAGCATTTGTTAATGGATTAACACCATTATT
AGCTCCTCATCATTCAGTCATGCTTCAAATGACAATTGCTGGACTTGTATTGTGTGATGTCCTATATCGATTAATAGTGG
GTGGATAA

Upstream 100 bases:

>100_bases
TAGAGTTTTCATAGCTGGAAAGCATAGCTCTCCATTTCATCAAAAACTAACACCTCCTCGCTTCGCTCGGAAGTGTAAAT
TTACAACTGATAAAATCTGG

Downstream 100 bases:

>100_bases
AATGAAAAGCTACATTGTATCCATAGGGGAAACCCCCTATTGGGATGAACCTTTTAGTAAAAGCTTCACCAAAACCTAAC
ACCTCCTCGCTTACGCTCGG

Product: NADH-ubiquinone oxidoreductase subunit 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MMLMDTSLIGAINLTIHAFLVGSLLLGLHRKIMARIQGRPGPPIIQYLLHTLKFYVKEITFPITAGNPLYIFVALLDIAI
WLAALIIAIDFKSSLLIIIGIYVLQKIVEHGCGLSSGSPYGKIGGVRSVFSAAAEVPLFAVVAAIYLTTHSVLISDILSY
QEIHGSLLFKMPICAFAFFILLVSKAPNSPFGIVKGKDIVSGYMTEHYGLLGAIIYIAEAIAYFVLLWLFIAVFIGPLVI
NSPVLTLAVMVVMTVILAFVNGLTPLLAPHHSVMLQMTIAGLVLCDVLYRLIVGG

Sequences:

>Translated_295_residues
MMLMDTSLIGAINLTIHAFLVGSLLLGLHRKIMARIQGRPGPPIIQYLLHTLKFYVKEITFPITAGNPLYIFVALLDIAI
WLAALIIAIDFKSSLLIIIGIYVLQKIVEHGCGLSSGSPYGKIGGVRSVFSAAAEVPLFAVVAAIYLTTHSVLISDILSY
QEIHGSLLFKMPICAFAFFILLVSKAPNSPFGIVKGKDIVSGYMTEHYGLLGAIIYIAEAIAYFVLLWLFIAVFIGPLVI
NSPVLTLAVMVVMTVILAFVNGLTPLLAPHHSVMLQMTIAGLVLCDVLYRLIVGG
>Mature_295_residues
MMLMDTSLIGAINLTIHAFLVGSLLLGLHRKIMARIQGRPGPPIIQYLLHTLKFYVKEITFPITAGNPLYIFVALLDIAI
WLAALIIAIDFKSSLLIIIGIYVLQKIVEHGCGLSSGSPYGKIGGVRSVFSAAAEVPLFAVVAAIYLTTHSVLISDILSY
QEIHGSLLFKMPICAFAFFILLVSKAPNSPFGIVKGKDIVSGYMTEHYGLLGAIIYIAEAIAYFVLLWLFIAVFIGPLVI
NSPVLTLAVMVVMTVILAFVNGLTPLLAPHHSVMLQMTIAGLVLCDVLYRLIVGG

Specific function: Hydrogen metabolism; FHL pathway. [C]

COG id: COG0650

COG function: function code C; Formate hydrogenlyase subunit 4

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y520_METJA (Q57940)

Other databases:

- EMBL:   L77117
- PIR:   H64364
- RefSeq:   NP_247498.1
- ProteinModelPortal:   Q57940
- GeneID:   1451384
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0520
- NMPDR:   fig|243232.1.peg.535
- TIGR:   MJ0520
- HOGENOM:   HBG539074
- OMA:   HRKVIAR
- ProtClustDB:   CLSK876222
- BioCyc:   MJAN243232:MJ_0520-MONOMER
- BRENDA:   1.6.5.3
- InterPro:   IPR001694
- PANTHER:   PTHR11432

Pfam domain/function: PF00146 NADHdh

EC number: =1.6.5.3

Molecular weight: Translated: 31909; Mature: 31909

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xcffd010)-; HASH(0xae406e4)-; HASH(0xd0e4594)-; HASH(0xd0e1cfc)-; HASH(0xcecb080)-; HASH(0xbb35360)-; HASH(0xcc4fb54)-; HASH(0xb0fe1f0)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure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CCHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087