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Identifier: 15645737

GI number: 15645737

Start: 1188610

End: 1189167

Strand: Reverse

Name: Not Available

Synonym: HP1123

Alternate gene names: 15645737

Gene position: 1189167-1188610 (Counterclockwise)

Preceding gene: 15645738

Following gene: 15645736

Centisome position: 71.3

GC content: 43.55

Gene sequence:

>558_bases
ATGCAAAACCATGATTTAGAGTCAATCAAACAAGCCGCTTTGATTGAATATGAAGTGAGAGAACAAGGCTCTAGTATTGT
GCTAGACAGCAATATTTCCAAAGAGCCTTTAGAGTTTATTATAGGCACTAATCAAATCATAGCAGGGTTAGAAAAGGCGG
TATTAAAGGCTCAAATTGGCGAGTGGGAAGAGGTTGTCATCGCCCCAGAGGAAGCTTATGGGGTTTATGAAAGCAGCTAT
TTGCAAGAAGTCCCTAGAGATCAATTTGAAGGCATTGAATTAGAAAAAGGCATGAGCGTTTTTGGGCAAACTGAAGACAA
TCAAACCATTCAAGCCATTATCAAAGACTTTAGCGCTACGCATGTGATGGTGGATTATAACCACCCGTTAGCCGGGAAAA
CTTTAGCGTTTCGTTTCAAGGTTTTAGGTTTTAGGGAAGTGAGCGAAGAAGAAATTTTAGCTTCACACCATGGCGGTGGG
ACAGGTTGCTGTGGCGGTCATGGGGGTCATGGCGGAAAGAAAGGTGGGGGTTGTGGTTGCTCATGTTCGCATGGGTAG

Upstream 100 bases:

>100_bases
AACTATTATAAATTTTTAAACACTTTGCAACACTTGTATCCTTCAAGCGAACAAGCTAAAATGGCGCAAAAAATCTTAGA
AAACAAGGAGAAACACCACC

Downstream 100 bases:

>100_bases
TAAGGTATAGGAGTATTTAAAAGGCAAGGTCATGAATAGTTCTAATCTCAAAAATTGGCTATTCCCTACCATTTGCTTTT
TTTTATTTTGTTATATTTTA

Product: peptidyl-prolyl cis-trans isomerase, FKBP-type rotamase (slyD)

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MQNHDLESIKQAALIEYEVREQGSSIVLDSNISKEPLEFIIGTNQIIAGLEKAVLKAQIGEWEEVVIAPEEAYGVYESSY
LQEVPRDQFEGIELEKGMSVFGQTEDNQTIQAIIKDFSATHVMVDYNHPLAGKTLAFRFKVLGFREVSEEEILASHHGGG
TGCCGGHGGHGGKKGGGCGCSCSHG

Sequences:

>Translated_185_residues
MQNHDLESIKQAALIEYEVREQGSSIVLDSNISKEPLEFIIGTNQIIAGLEKAVLKAQIGEWEEVVIAPEEAYGVYESSY
LQEVPRDQFEGIELEKGMSVFGQTEDNQTIQAIIKDFSATHVMVDYNHPLAGKTLAFRFKVLGFREVSEEEILASHHGGG
TGCCGGHGGHGGKKGGGCGCSCSHG
>Mature_185_residues
MQNHDLESIKQAALIEYEVREQGSSIVLDSNISKEPLEFIIGTNQIIAGLEKAVLKAQIGEWEEVVIAPEEAYGVYESSY
LQEVPRDQFEGIELEKGMSVFGQTEDNQTIQAIIKDFSATHVMVDYNHPLAGKTLAFRFKVLGFREVSEEEILASHHGGG
TGCCGGHGGHGGKKGGGCGCSCSHG

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=139, Percent_Identity=35.9712230215827, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 19998; Mature: 19998

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNHDLESIKQAALIEYEVREQGSSIVLDSNISKEPLEFIIGTNQIIAGLEKAVLKAQIG
CCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHCC
EWEEVVIAPEEAYGVYESSYLQEVPRDQFEGIELEKGMSVFGQTEDNQTIQAIIKDFSAT
CCEEEEECCHHHHCCHHHHHHHHCCHHHHCCEEHHCCCHHCCCCCCCHHHHHHHHHCCCE
HVMVDYNHPLAGKTLAFRFKVLGFREVSEEEILASHHGGGTGCCGGHGGHGGKKGGGCGC
EEEEECCCCCCCCEEEEEEEECCCHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
SCSHG
CCCCC
>Mature Secondary Structure
MQNHDLESIKQAALIEYEVREQGSSIVLDSNISKEPLEFIIGTNQIIAGLEKAVLKAQIG
CCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHCC
EWEEVVIAPEEAYGVYESSYLQEVPRDQFEGIELEKGMSVFGQTEDNQTIQAIIKDFSAT
CCEEEEECCHHHHCCHHHHHHHHCCHHHHCCEEHHCCCHHCCCCCCCHHHHHHHHHCCCE
HVMVDYNHPLAGKTLAFRFKVLGFREVSEEEILASHHGGGTGCCGGHGGHGGKKGGGCGC
EEEEECCCCCCCCEEEEEEEECCCHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
SCSHG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]