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The map label for this gene is bioH [H]

Identifier: 15607082

GI number: 15607082

Start: 1504917

End: 1505540

Strand: Direct

Name: bioH [H]

Synonym: aq_2138

Alternate gene names: 15607082

Gene position: 1504917-1505540 (Clockwise)

Preceding gene: 15607081

Following gene: 15607083

Centisome position: 97.01

GC content: 42.79

Gene sequence:

>624_bases
ATGCTCAAAAATCCCCTCTTTATCCACGGATGGGCGTTTTCCTCAAAGGTATTTAATGACTTTCACGGTATAAAGTACGA
CCTTCCCGGGCACGGAAAAAATAAAAATCCCTACGAGAGTATAGAAAAAGTAGTGGAAGAAATTGGAAAAATAGCCACTT
CAAAACACGACGTTGTAGGCTGGTCCCTTGGAGGAAGTCTGGCACTTCTTTTCGCTTACAGGTATCCAGAAAAGGTAAAC
AGGTTGATCCTTATAGGGACCACTCCCCACTTTAAAGGAGCGTGGAGCGAAAAGAATATAAGGGCTATGAAACTCCTGAT
AAAGAAGAAGGGGATAAAAGCTTTCAGGGAACTAGCCTACGGGAAATTTGAGGACTTCTTTGACGAGGAGCAGGGCATGA
GATTTCTTGAGGACTACGTGAACCTGAACTTGTACACTGTACTTCCCTATATAAAGAAGGAGGTTTACCTGATACACGGA
GTTTCGGACAGAATAGTTCCGTATTCAGAAGCTTACAAACTGCATAGAGCTTTAAAATGCTCTAAATTAATCCTTCTCGG
AGGAGGACACTTCCCTGTCAGAAATGAAGAACACCTTAGGAAGGCAATTCTCAAGGGCTACTGA

Upstream 100 bases:

>100_bases
AAAGCCTGATGAAGTTATAGACTACCCCCACCCCTACATTCAGGAGTTCGTGGGAGCTATCAAGTCCTGCCTCAAACACG
CCAAGGTTTAGAATAAACCT

Downstream 100 bases:

>100_bases
AACCTACGAAAAGTGGGCAGTTCCCCAGAGAAAGTCTGCAAAAATCCTAGTGGAGTTCGTGAAGCCCTCAGGCCTGGTTC
TTGACCTCGGGTGTGGGACG

Product: hypothetical protein

Products: NA

Alternate protein names: Biotin synthesis protein BioH [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MLKNPLFIHGWAFSSKVFNDFHGIKYDLPGHGKNKNPYESIEKVVEEIGKIATSKHDVVGWSLGGSLALLFAYRYPEKVN
RLILIGTTPHFKGAWSEKNIRAMKLLIKKKGIKAFRELAYGKFEDFFDEEQGMRFLEDYVNLNLYTVLPYIKKEVYLIHG
VSDRIVPYSEAYKLHRALKCSKLILLGGGHFPVRNEEHLRKAILKGY

Sequences:

>Translated_207_residues
MLKNPLFIHGWAFSSKVFNDFHGIKYDLPGHGKNKNPYESIEKVVEEIGKIATSKHDVVGWSLGGSLALLFAYRYPEKVN
RLILIGTTPHFKGAWSEKNIRAMKLLIKKKGIKAFRELAYGKFEDFFDEEQGMRFLEDYVNLNLYTVLPYIKKEVYLIHG
VSDRIVPYSEAYKLHRALKCSKLILLGGGHFPVRNEEHLRKAILKGY
>Mature_207_residues
MLKNPLFIHGWAFSSKVFNDFHGIKYDLPGHGKNKNPYESIEKVVEEIGKIATSKHDVVGWSLGGSLALLFAYRYPEKVN
RLILIGTTPHFKGAWSEKNIRAMKLLIKKKGIKAFRELAYGKFEDFFDEEQGMRFLEDYVNLNLYTVLPYIKKEVYLIHG
VSDRIVPYSEAYKLHRALKCSKLILLGGGHFPVRNEEHLRKAILKGY

Specific function: Shows carboxylesterase activity with a preference for short chain fatty acid esters (acyl chain length of up to 6 carbons). Also displays a weak thioesterase activity. Can form a complex with CoA, and may be involved in the condensation of CoA and pimelic

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010076 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 23875; Mature: 23875

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKNPLFIHGWAFSSKVFNDFHGIKYDLPGHGKNKNPYESIEKVVEEIGKIATSKHDVVG
CCCCCEEEEEECHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEE
WSLGGSLALLFAYRYPEKVNRLILIGTTPHFKGAWSEKNIRAMKLLIKKKGIKAFRELAY
EECCCHHHHHHHHHCHHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GKFEDFFDEEQGMRFLEDYVNLNLYTVLPYIKKEVYLIHGVSDRIVPYSEAYKLHRALKC
HHHHHHHCHHHHHHHHHHHHCCCCEEECHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHH
SKLILLGGGHFPVRNEEHLRKAILKGY
CEEEEEECCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MLKNPLFIHGWAFSSKVFNDFHGIKYDLPGHGKNKNPYESIEKVVEEIGKIATSKHDVVG
CCCCCEEEEEECHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEE
WSLGGSLALLFAYRYPEKVNRLILIGTTPHFKGAWSEKNIRAMKLLIKKKGIKAFRELAY
EECCCHHHHHHHHHCHHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GKFEDFFDEEQGMRFLEDYVNLNLYTVLPYIKKEVYLIHGVSDRIVPYSEAYKLHRALKC
HHHHHHHCHHHHHHHHHHHHCCCCEEECHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHH
SKLILLGGGHFPVRNEEHLRKAILKGY
CEEEEEECCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]