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The map label for this gene is metX

Identifier: 15602731

GI number: 15602731

Start: 1019060

End: 1020142

Strand: Reverse

Name: metX

Synonym: PM0866

Alternate gene names: 15602731

Gene position: 1020142-1019060 (Counterclockwise)

Preceding gene: 15602733

Following gene: 15602727

Centisome position: 45.19

GC content: 39.52

Gene sequence:

>1083_bases
ATGGCTGTACAGAAAGTGAAATTGTTTACGGAAGCTCCTTTTACCTTAAGTTTAGGCGGGACGCTCCAAGATATTGAGAT
CGCATATCAAACTTATGGTGAGTTGAATAAAGAGAAAACAAATGCGATTCTTATTTGTCATGCATTAACGGGGGATGCAG
AGCCTTATTTTGCTGATCATTCACAGCGTGGTTGGTGGCAGACCTTTATGGGGGAAGGGCTTGCTTTGGATACGTCTCAA
TATTTCTTTATTTGTTCTAATGTGTTGGGAGGATGTAAAGGTACAACAGGTCCTTCCTCTATTAACCCTAAAACCAATAA
ACCTTACGGCAGTCAATTTCCGAACATTATTGTGCAAGATATTGTTGCGCTACAAAGAGCATTATTGACACATCTCAATA
TTCCTCGTTTACATGCTGTGATTGGTGGCTCTTTTGGTGGGATGCAAGCTACCCAATGGGCGATTGATTATCCTGATGAT
GTCAGTAATGTCATTAATTTATGTTCTTCTTTGTTATTTGGTGCAGAAGCGATTGGTTTTAATCATGTGATGCGACAAGC
AGTGATTAATGATCCCAATTTTAATGGCGGAGATTACTATGATAGTCAACCTCCGGAAAAAGGATTAGCGATTGCGCGTA
TGTTGGGGATGTTGACTTACCGAACCGATTTACAATTAACCAAAGCGTTTGGGCGTGCCACAAAAGCAGAAACGGAATTT
TGGGGCGATTACTTTCAAGTCGAATCCTATTTAAGTTACCAAGGAAAAAAATTCTTAGCGCGCTTTGATGCCAATAGTTA
TCTTCATTTGCTCAGAGCGTTAGATTTATATGATCCGGGCTTTCAATATGAAAGCTTGTCCGCGGCATTAGCCAGAATCA
AAGCACGTTACACGTTAGTGGCTGTCGAAAATGATCAATTATTTAAGTTGACGGAGCTACAAAAGAGTAAAAAGCTCCTC
GAGGAAAGTGGCGTCGATTTAGTATATTATCAATTTTCTTCCGATTATGGACACGATGCATTTTTAGTTGATTATGCTTT
TTTTGAGAAGAAAATTCGATTAGCTCTGGCTAATCAAGACTAG

Upstream 100 bases:

>100_bases
CAAGCTGAATTTTAGTAGATTTGTACGTAAAGATGTTTAGACGTCCATAAATCCAATAAAAGTAAAGTGAACATAACAAC
AAGAATAAGCAGGCGGTAGC

Downstream 100 bases:

>100_bases
GTTCTGTACGTATTTTCTGCATTTGGTGATCTTCGAATTTTTTCCTTAATTCCAGCAGAGGTTGTCCACTCGGTAAACAT
AAATCAGGGGCAATTTCAAA

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MAVQKVKLFTEAPFTLSLGGTLQDIEIAYQTYGELNKEKTNAILICHALTGDAEPYFADHSQRGWWQTFMGEGLALDTSQ
YFFICSNVLGGCKGTTGPSSINPKTNKPYGSQFPNIIVQDIVALQRALLTHLNIPRLHAVIGGSFGGMQATQWAIDYPDD
VSNVINLCSSLLFGAEAIGFNHVMRQAVINDPNFNGGDYYDSQPPEKGLAIARMLGMLTYRTDLQLTKAFGRATKAETEF
WGDYFQVESYLSYQGKKFLARFDANSYLHLLRALDLYDPGFQYESLSAALARIKARYTLVAVENDQLFKLTELQKSKKLL
EESGVDLVYYQFSSDYGHDAFLVDYAFFEKKIRLALANQD

Sequences:

>Translated_360_residues
MAVQKVKLFTEAPFTLSLGGTLQDIEIAYQTYGELNKEKTNAILICHALTGDAEPYFADHSQRGWWQTFMGEGLALDTSQ
YFFICSNVLGGCKGTTGPSSINPKTNKPYGSQFPNIIVQDIVALQRALLTHLNIPRLHAVIGGSFGGMQATQWAIDYPDD
VSNVINLCSSLLFGAEAIGFNHVMRQAVINDPNFNGGDYYDSQPPEKGLAIARMLGMLTYRTDLQLTKAFGRATKAETEF
WGDYFQVESYLSYQGKKFLARFDANSYLHLLRALDLYDPGFQYESLSAALARIKARYTLVAVENDQLFKLTELQKSKKLL
EESGVDLVYYQFSSDYGHDAFLVDYAFFEKKIRLALANQD
>Mature_359_residues
AVQKVKLFTEAPFTLSLGGTLQDIEIAYQTYGELNKEKTNAILICHALTGDAEPYFADHSQRGWWQTFMGEGLALDTSQY
FFICSNVLGGCKGTTGPSSINPKTNKPYGSQFPNIIVQDIVALQRALLTHLNIPRLHAVIGGSFGGMQATQWAIDYPDDV
SNVINLCSSLLFGAEAIGFNHVMRQAVINDPNFNGGDYYDSQPPEKGLAIARMLGMLTYRTDLQLTKAFGRATKAETEFW
GDYFQVESYLSYQGKKFLARFDANSYLHLLRALDLYDPGFQYESLSAALARIKARYTLVAVENDQLFKLTELQKSKKLLE
ESGVDLVYYQFSSDYGHDAFLVDYAFFEKKIRLALANQD

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=235, Percent_Identity=36.5957446808511, Blast_Score=155, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_PASMU (P57884)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245803.1
- ProteinModelPortal:   P57884
- SMR:   P57884
- GeneID:   1244213
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0866
- NMPDR:   fig|272843.1.peg.866
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- ProtClustDB:   PRK00175
- BioCyc:   PMUL272843:PM0866-MONOMER
- BRENDA:   2.3.1.31
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 40312; Mature: 40181

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: ACT_SITE 144-144 ACT_SITE 338-338

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVQKVKLFTEAPFTLSLGGTLQDIEIAYQTYGELNKEKTNAILICHALTGDAEPYFADH
CCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCC
SQRGWWQTFMGEGLALDTSQYFFICSNVLGGCKGTTGPSSINPKTNKPYGSQFPNIIVQD
CCCCHHHHHHCCCEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
IVALQRALLTHLNIPRLHAVIGGSFGGMQATQWAIDYPDDVSNVINLCSSLLFGAEAIGF
HHHHHHHHHHHCCCCHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
NHVMRQAVINDPNFNGGDYYDSQPPEKGLAIARMLGMLTYRTDLQLTKAFGRATKAETEF
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
WGDYFQVESYLSYQGKKFLARFDANSYLHLLRALDLYDPGFQYESLSAALARIKARYTLV
HHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEEEE
AVENDQLFKLTELQKSKKLLEESGVDLVYYQFSSDYGHDAFLVDYAFFEKKIRLALANQD
EECCCCEEHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEHHHHHHHHHEEEECCCC
>Mature Secondary Structure 
AVQKVKLFTEAPFTLSLGGTLQDIEIAYQTYGELNKEKTNAILICHALTGDAEPYFADH
CCCEEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCC
SQRGWWQTFMGEGLALDTSQYFFICSNVLGGCKGTTGPSSINPKTNKPYGSQFPNIIVQD
CCCCHHHHHHCCCEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
IVALQRALLTHLNIPRLHAVIGGSFGGMQATQWAIDYPDDVSNVINLCSSLLFGAEAIGF
HHHHHHHHHHHCCCCHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
NHVMRQAVINDPNFNGGDYYDSQPPEKGLAIARMLGMLTYRTDLQLTKAFGRATKAETEF
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
WGDYFQVESYLSYQGKKFLARFDANSYLHLLRALDLYDPGFQYESLSAALARIKARYTLV
HHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEEEE
AVENDQLFKLTELQKSKKLLEESGVDLVYYQFSSDYGHDAFLVDYAFFEKKIRLALANQD
EECCCCEEHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEHHHHHHHHHEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100