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The map label for this gene is modE [H]

Identifier: 15602611

GI number: 15602611

Start: 880209

End: 881000

Strand: Direct

Name: modE [H]

Synonym: PM0746

Alternate gene names: 15602611

Gene position: 880209-881000 (Clockwise)

Preceding gene: 15602606

Following gene: 15602619

Centisome position: 38.99

GC content: 38.38

Gene sequence:

>792_bases
ATGACATTAACGAGTGAAATTTTGCTCACAATAAAGTTGCAACAGCAATTATTTGTTGATCCAAAAAGAATTCGCTTATT
AAAAGAAATTCAGAAATGTGGTTCCATTAACCAAGCTGCTAAAAATGCCAAAGTCAGCTACAAAAGTGCATGGGATCATT
TAGCCGCTATGAATGAAATCAGCCCCAAACCTTTACTTGAACGTAATGTGGGGGGAAAAAATGGCGGTGGTACCGAATTA
ACGGTGTATGCACAACGTTTATTACAGCTGTATGATTTGCTCGAACATACTCAACAAAAAGCCTTTCATATCTTGCAAGA
TGAAAACTTACCTTTAGATAGCGTACTGCATGCGACTGCCCGCTTTTCCTTACAAAGTAGTGCGAGAAACCAATTCTTTG
GAGATATTGTTGCACTACGCCATGAAAATATCCATTGCTTTGTGGCGATTCAAATTAAAGGATTAGCACAGCCATTAACC
GTTTCGATCACAGAAAAAAGTGCGCAGCGTCTGAAACTCACGTTAGGCAAAGAAGTGATGATGATGATCAAAGCACCATG
GGTCAAAGTACATCGTGAAAAACCAGAGGGAGTCAACACCTTCTTGGTCAATGTAAAAGAAATCACGGATAAAGGAGATG
TGGAAGAAGTCATTTTAACCTCTATCAACAAACACGCTGATGAAGATATGGAATTTTGTGCCACACTCAATAAAGCAGAA
AATTTGAAACCAGATGAACAAATTTGGATCAGTATTGATCCCGAACAAGTGATCTTAGCAACATTGTATTAA

Upstream 100 bases:

>100_bases
ATTCATGCACATAATTTGATAAAGAAAGGCTATCTAAAAAATACACTTTCACTTAGAATGTAAGCGTATTGTCAGCATTG
AACTCAATATGGGAGGAAAC

Downstream 100 bases:

>100_bases
ATACAAAAAATAGGGGGATATATATCCCCTTAACTGTACAAATTAAAGTGTAATTTCATCAATAGGTTTACCAAAACTGG
GAATAAATACCTCAATAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MTLTSEILLTIKLQQQLFVDPKRIRLLKEIQKCGSINQAAKNAKVSYKSAWDHLAAMNEISPKPLLERNVGGKNGGGTEL
TVYAQRLLQLYDLLEHTQQKAFHILQDENLPLDSVLHATARFSLQSSARNQFFGDIVALRHENIHCFVAIQIKGLAQPLT
VSITEKSAQRLKLTLGKEVMMMIKAPWVKVHREKPEGVNTFLVNVKEITDKGDVEEVILTSINKHADEDMEFCATLNKAE
NLKPDEQIWISIDPEQVILATLY

Sequences:

>Translated_263_residues
MTLTSEILLTIKLQQQLFVDPKRIRLLKEIQKCGSINQAAKNAKVSYKSAWDHLAAMNEISPKPLLERNVGGKNGGGTEL
TVYAQRLLQLYDLLEHTQQKAFHILQDENLPLDSVLHATARFSLQSSARNQFFGDIVALRHENIHCFVAIQIKGLAQPLT
VSITEKSAQRLKLTLGKEVMMMIKAPWVKVHREKPEGVNTFLVNVKEITDKGDVEEVILTSINKHADEDMEFCATLNKAE
NLKPDEQIWISIDPEQVILATLY
>Mature_262_residues
TLTSEILLTIKLQQQLFVDPKRIRLLKEIQKCGSINQAAKNAKVSYKSAWDHLAAMNEISPKPLLERNVGGKNGGGTELT
VYAQRLLQLYDLLEHTQQKAFHILQDENLPLDSVLHATARFSLQSSARNQFFGDIVALRHENIHCFVAIQIKGLAQPLTV
SITEKSAQRLKLTLGKEVMMMIKAPWVKVHREKPEGVNTFLVNVKEITDKGDVEEVILTSINKHADEDMEFCATLNKAEN
LKPDEQIWISIDPEQVILATLY

Specific function: The modE-Mo complex acts as a repressor of the modABC operon, involved in the transport of molybdate. Upon binding molybdate, the conformation of the protein changes, promoting dimerization of ModE-Mo. The protein dimer is then competent to bind a DNA reg

COG id: COG2005

COG function: function code R; N-terminal domain of molybdenum-binding protein

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the modE family [H]

Homologues:

Organism=Escherichia coli, GI1786976, Length=265, Percent_Identity=44.1509433962264, Blast_Score=176, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR004606
- InterPro:   IPR008995
- InterPro:   IPR003725
- InterPro:   IPR016462
- InterPro:   IPR005116
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03459 TOBE [H]

EC number: NA

Molecular weight: Translated: 29706; Mature: 29575

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTSEILLTIKLQQQLFVDPKRIRLLKEIQKCGSINQAAKNAKVSYKSAWDHLAAMNEI
CCCCHHEEEEEEEHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHCC
SPKPLLERNVGGKNGGGTELTVYAQRLLQLYDLLEHTQQKAFHILQDENLPLDSVLHATA
CCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
RFSLQSSARNQFFGDIVALRHENIHCFVAIQIKGLAQPLTVSITEKSAQRLKLTLGKEVM
HHHHHHHHHHHHHHHHHHEEECCEEEEEEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHH
MMIKAPWVKVHREKPEGVNTFLVNVKEITDKGDVEEVILTSINKHADEDMEFCATLNKAE
HHHHCCHHEEECCCCCCCEEEEEEHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
NLKPDEQIWISIDPEQVILATLY
CCCCCCEEEEEECCCEEEEEECC
>Mature Secondary Structure 
TLTSEILLTIKLQQQLFVDPKRIRLLKEIQKCGSINQAAKNAKVSYKSAWDHLAAMNEI
CCCHHEEEEEEEHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHCC
SPKPLLERNVGGKNGGGTELTVYAQRLLQLYDLLEHTQQKAFHILQDENLPLDSVLHATA
CCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
RFSLQSSARNQFFGDIVALRHENIHCFVAIQIKGLAQPLTVSITEKSAQRLKLTLGKEVM
HHHHHHHHHHHHHHHHHHEEECCEEEEEEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHH
MMIKAPWVKVHREKPEGVNTFLVNVKEITDKGDVEEVILTSINKHADEDMEFCATLNKAE
HHHHCCHHEEECCCCCCCEEEEEEHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
NLKPDEQIWISIDPEQVILATLY
CCCCCCEEEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 9325422 [H]