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The map label for this gene is gltA [H]

Identifier: 15602141

GI number: 15602141

Start: 312644

End: 313930

Strand: Reverse

Name: gltA [H]

Synonym: PM0276

Alternate gene names: 15602141

Gene position: 313930-312644 (Counterclockwise)

Preceding gene: 15602149

Following gene: 15602140

Centisome position: 13.91

GC content: 42.58

Gene sequence:

>1287_bases
ATGTCTGAATTAACTGCAAAACTGACCCTTAGCGATGGACGTGAATATGACCTACCTGTACACAAAGGCTCTCTTGGTTA
TGATGCAATAGATGTACAATCTCTGGTTAAGAATAAACTGTTCACCTTCGATCCAGGCTTTATGTCAACAGCCTGTTGTC
GCTCTGAAATTACTTATATCGATGGCGATAATGGTGTTTTATTACATCGAGGCTACCCTATTGCTGAGCTGGCTAAAAAT
GCAGATTACCTTGAAGTTGCGCATTTATTGCTTTTTGGTGAAAGACCGTCTCCTGAAGAATACAAAAACTTTACGCAATT
AGTCCGTCGTCATACCCTCGTTCACGAACAAATCTCTCGCTTTTTCCACGGTTTCCGTCGTGACTCACACCCAATGGCAA
TCATGTGTGGGGTAAGTGGTGCTTTAGCCGCCTTCTACCATGACTCCTTAGATATTAATGATATTACTCACCGTGAAATC
ACCGCAATTCGTTTACTTGCTAAAATGCCAACTTTGGCGGCGATGTGCTATAAATACTCGATTGGTCAGCCTTTCATGTT
CCCGCAAAATCATCTCTCTTATTCCGGTAATTTCCTTTACATGATGTTTGCGACGCCTTGTGAACCTTACATCGTTAACC
CGGTATTAGAGCGTGCCATGGATCGTATTTTCATTTTGCATGCTGACCATGAACAAAATGCGTCCACCTCAACCGTGCGC
ACCGCAGCCTCTTCTGGCGCCAATCCATTTGCCTGTATTGCAGCAGGTATTGCCTCACTTTGGGGACCTGCTCATGGTGG
TGCTAATGAAGCCTGTATCAATATGTTAGAAGAAATTGGTACAGTCGATCGTATTCCTGAATTTATTGCTCGTGCAAAAG
ACAAAAATGATCCATTCCGATTAATGGGCTTTGGTCACCGTGTGTATAAAAACTATGACCCGCGTGCCAAAGTCATGCGT
CAAACTTGTCATGAAGTTTTAAAAGAGCTCAATATTCAAAATCCGCTCTTTGATGTTGCCATGGAATTAGAACGTATTGC
ACTCAGTGACCCATATTTCATTGACCATAAGTTGTATCCAAATGTGGATTTCTATTCTGGTATTATTCTCAAGGCTATTG
GCATTCCAACATCCATGTTTACGGTGATGTTCGCCTTAGCCAGAACGGTAGGTTGGATTGCACATTGGAAAGAAATGTTC
AAACCGGGCAATATGAAAATTGTCCGCCCTCGCCAGCTCTACATGGGTGAAAAAGAACGTTCTTTTGAAGCTATGGACAA
GAGTTAA

Upstream 100 bases:

>100_bases
ACAATTTTTTTTTCACAATAATGAAGACACTGACTCTTTTAAGCTTTATAGTTAATTAAAATGCAATAAAACACAACTTA
CTAAAAAGGAAGGATGACTT

Downstream 100 bases:

>100_bases
AAATACGCGAAAAACTGACCGCACTTTATTGCACCTGCCGAGCACGACGTCACCGGCAGGTGCACTCTTAATACAATGCC
TTTCCTTCCCCGCTATCACT

Product: GltA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MSELTAKLTLSDGREYDLPVHKGSLGYDAIDVQSLVKNKLFTFDPGFMSTACCRSEITYIDGDNGVLLHRGYPIAELAKN
ADYLEVAHLLLFGERPSPEEYKNFTQLVRRHTLVHEQISRFFHGFRRDSHPMAIMCGVSGALAAFYHDSLDINDITHREI
TAIRLLAKMPTLAAMCYKYSIGQPFMFPQNHLSYSGNFLYMMFATPCEPYIVNPVLERAMDRIFILHADHEQNASTSTVR
TAASSGANPFACIAAGIASLWGPAHGGANEACINMLEEIGTVDRIPEFIARAKDKNDPFRLMGFGHRVYKNYDPRAKVMR
QTCHEVLKELNIQNPLFDVAMELERIALSDPYFIDHKLYPNVDFYSGIILKAIGIPTSMFTVMFALARTVGWIAHWKEMF
KPGNMKIVRPRQLYMGEKERSFEAMDKS

Sequences:

>Translated_428_residues
MSELTAKLTLSDGREYDLPVHKGSLGYDAIDVQSLVKNKLFTFDPGFMSTACCRSEITYIDGDNGVLLHRGYPIAELAKN
ADYLEVAHLLLFGERPSPEEYKNFTQLVRRHTLVHEQISRFFHGFRRDSHPMAIMCGVSGALAAFYHDSLDINDITHREI
TAIRLLAKMPTLAAMCYKYSIGQPFMFPQNHLSYSGNFLYMMFATPCEPYIVNPVLERAMDRIFILHADHEQNASTSTVR
TAASSGANPFACIAAGIASLWGPAHGGANEACINMLEEIGTVDRIPEFIARAKDKNDPFRLMGFGHRVYKNYDPRAKVMR
QTCHEVLKELNIQNPLFDVAMELERIALSDPYFIDHKLYPNVDFYSGIILKAIGIPTSMFTVMFALARTVGWIAHWKEMF
KPGNMKIVRPRQLYMGEKERSFEAMDKS
>Mature_427_residues
SELTAKLTLSDGREYDLPVHKGSLGYDAIDVQSLVKNKLFTFDPGFMSTACCRSEITYIDGDNGVLLHRGYPIAELAKNA
DYLEVAHLLLFGERPSPEEYKNFTQLVRRHTLVHEQISRFFHGFRRDSHPMAIMCGVSGALAAFYHDSLDINDITHREIT
AIRLLAKMPTLAAMCYKYSIGQPFMFPQNHLSYSGNFLYMMFATPCEPYIVNPVLERAMDRIFILHADHEQNASTSTVRT
AASSGANPFACIAAGIASLWGPAHGGANEACINMLEEIGTVDRIPEFIARAKDKNDPFRLMGFGHRVYKNYDPRAKVMRQ
TCHEVLKELNIQNPLFDVAMELERIALSDPYFIDHKLYPNVDFYSGIILKAIGIPTSMFTVMFALARTVGWIAHWKEMFK
PGNMKIVRPRQLYMGEKERSFEAMDKS

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=384, Percent_Identity=26.5625, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1786939, Length=424, Percent_Identity=71.9339622641509, Blast_Score=662, Evalue=0.0,
Organism=Escherichia coli, GI1786527, Length=369, Percent_Identity=31.7073170731707, Blast_Score=164, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17555174, Length=382, Percent_Identity=25.130890052356, Blast_Score=94, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319850, Length=372, Percent_Identity=24.1935483870968, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324328, Length=320, Percent_Identity=25, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24640124, Length=401, Percent_Identity=24.1895261845387, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24640126, Length=401, Percent_Identity=24.1895261845387, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21356863, Length=328, Percent_Identity=24.0853658536585, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: 624 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810
- InterPro:   IPR010953 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 48475; Mature: 48344

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS00480 CITRATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELTAKLTLSDGREYDLPVHKGSLGYDAIDVQSLVKNKLFTFDPGFMSTACCRSEITYI
CCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCHHHHHHHHCCCEEE
DGDNGVLLHRGYPIAELAKNADYLEVAHLLLFGERPSPEEYKNFTQLVRRHTLVHEQISR
ECCCCEEEECCCCHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FFHGFRRDSHPMAIMCGVSGALAAFYHDSLDINDITHREITAIRLLAKMPTLAAMCYKYS
HHHHHCCCCCCEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
IGQPFMFPQNHLSYSGNFLYMMFATPCEPYIVNPVLERAMDRIFILHADHEQNASTSTVR
CCCCCCCCCCCCCCCCCEEEEEEECCCCCCEECHHHHHHHHEEEEEECCCCCCCCHHHHH
TAASSGANPFACIAAGIASLWGPAHGGANEACINMLEEIGTVDRIPEFIARAKDKNDPFR
HHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEE
LMGFGHRVYKNYDPRAKVMRQTCHEVLKELNIQNPLFDVAMELERIALSDPYFIDHKLYP
EEECCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEECCCCCC
NVDFYSGIILKAIGIPTSMFTVMFALARTVGWIAHWKEMFKPGNMKIVRPRQLYMGEKER
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHCCCHHH
SFEAMDKS
HHHHCCCC
>Mature Secondary Structure 
SELTAKLTLSDGREYDLPVHKGSLGYDAIDVQSLVKNKLFTFDPGFMSTACCRSEITYI
CCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCHHHHHHHHCCCEEE
DGDNGVLLHRGYPIAELAKNADYLEVAHLLLFGERPSPEEYKNFTQLVRRHTLVHEQISR
ECCCCEEEECCCCHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FFHGFRRDSHPMAIMCGVSGALAAFYHDSLDINDITHREITAIRLLAKMPTLAAMCYKYS
HHHHHCCCCCCEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
IGQPFMFPQNHLSYSGNFLYMMFATPCEPYIVNPVLERAMDRIFILHADHEQNASTSTVR
CCCCCCCCCCCCCCCCCEEEEEEECCCCCCEECHHHHHHHHEEEEEECCCCCCCCHHHHH
TAASSGANPFACIAAGIASLWGPAHGGANEACINMLEEIGTVDRIPEFIARAKDKNDPFR
HHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEE
LMGFGHRVYKNYDPRAKVMRQTCHEVLKELNIQNPLFDVAMELERIALSDPYFIDHKLYP
EEECCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEECCCCCC
NVDFYSGIILKAIGIPTSMFTVMFALARTVGWIAHWKEMFKPGNMKIVRPRQLYMGEKER
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHCCCHHH
SFEAMDKS
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]