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The map label for this gene is queC

Identifier: 15602051

GI number: 15602051

Start: 208410

End: 209096

Strand: Reverse

Name: queC

Synonym: PM0186

Alternate gene names: 15602051

Gene position: 209096-208410 (Counterclockwise)

Preceding gene: 15602052

Following gene: 15602050

Centisome position: 9.26

GC content: 41.48

Gene sequence:

>687_bases
ATGCAGTTAACCAACCCAAACCGCGATCGTAAAGCGGTCGTTATCTTTTCGGGTGGACAAGATTCCACCACTTGTCTCTT
TCAAGCAATACAAGATTATGGCGTAGAAAATGTGGAAGTTGTAACGTTCCAATACGGTCAACGCCACGCGATTGAATTAG
AGAAAGCTAAATGGATTGCCCAAGATCTTGGCGTCAAACAAACGTTAATTGACACTTCCGTCATTAAAGCGATTACGCAA
AATGCCTTAATGGACGAACAGGCAAGAATTGAGCAACACGGCAGTACACCGAATACTTTCGTTGACGGTCGCAATGCCCT
GTTTTTACTTTATACCGCCATCTATGCCAAAGGTCAGGGTATTCAAGATATTATCACAGGCGTCTGTGAAACGGATTTTA
GTGGCTATCCAGATTGTCGTGATGTGTTTATTAAATCCATGAATGTCACGCTTAATCTGGCAATGGATTACCAATTCCAT
CTTAAAACCCCTTTAATGTATCTCACAAAAGCACAAACTTGGCAATTAGCGGATGAACTCGGTGTATTAGATTATATTCG
TCAACATACCCACACTTGTTATATGGGAGTGGAACAAGGTTGCGGTGAATGCCCGAGTTGTGTATTACGCGAGAAAGGAT
TGCGTGAATATTTATCTAGTAAAAGTGAGGCGGAAATTGATGTTTAA

Upstream 100 bases:

>100_bases
AAACGACGTTTAAACAAGCCTACTGTTTCTTTTCATAGTGGTTCGTAACCCTCCCACTTGAACAACCAACAATTGTTCGA
AACAAAACTAGGAAAATAGT

Downstream 100 bases:

>100_bases
AATTGCAAAAGAATTTAGTTTTGATATGGCACATATGCTCGATGGGCATGATGGCAAATGCAAAAATTTACATGGGCATA
CTTACAAATTACAAGTAGAG

Product: hypothetical protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MQLTNPNRDRKAVVIFSGGQDSTTCLFQAIQDYGVENVEVVTFQYGQRHAIELEKAKWIAQDLGVKQTLIDTSVIKAITQ
NALMDEQARIEQHGSTPNTFVDGRNALFLLYTAIYAKGQGIQDIITGVCETDFSGYPDCRDVFIKSMNVTLNLAMDYQFH
LKTPLMYLTKAQTWQLADELGVLDYIRQHTHTCYMGVEQGCGECPSCVLREKGLREYLSSKSEAEIDV

Sequences:

>Translated_228_residues
MQLTNPNRDRKAVVIFSGGQDSTTCLFQAIQDYGVENVEVVTFQYGQRHAIELEKAKWIAQDLGVKQTLIDTSVIKAITQ
NALMDEQARIEQHGSTPNTFVDGRNALFLLYTAIYAKGQGIQDIITGVCETDFSGYPDCRDVFIKSMNVTLNLAMDYQFH
LKTPLMYLTKAQTWQLADELGVLDYIRQHTHTCYMGVEQGCGECPSCVLREKGLREYLSSKSEAEIDV
>Mature_228_residues
MQLTNPNRDRKAVVIFSGGQDSTTCLFQAIQDYGVENVEVVTFQYGQRHAIELEKAKWIAQDLGVKQTLIDTSVIKAITQ
NALMDEQARIEQHGSTPNTFVDGRNALFLLYTAIYAKGQGIQDIITGVCETDFSGYPDCRDVFIKSMNVTLNLAMDYQFH
LKTPLMYLTKAQTWQLADELGVLDYIRQHTHTCYMGVEQGCGECPSCVLREKGLREYLSSKSEAEIDV

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=219, Percent_Identity=48.4018264840183, Blast_Score=207, Evalue=6e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_PASMU (Q9CP69)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245123.1
- ProteinModelPortal:   Q9CP69
- SMR:   Q9CP69
- GeneID:   1243533
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0186
- NMPDR:   fig|272843.1.peg.186
- HOGENOM:   HBG553284
- OMA:   CETDYSG
- ProtClustDB:   CLSK870005
- BioCyc:   PMUL272843:PM0186-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25665; Mature: 25665

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLTNPNRDRKAVVIFSGGQDSTTCLFQAIQDYGVENVEVVTFQYGQRHAIELEKAKWIA
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEHHHHHHHH
QDLGVKQTLIDTSVIKAITQNALMDEQARIEQHGSTPNTFVDGRNALFLLYTAIYAKGQG
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHCCCC
IQDIITGVCETDFSGYPDCRDVFIKSMNVTLNLAMDYQFHLKTPLMYLTKAQTWQLADEL
HHHHHHHHHHCCCCCCCCHHHHHHHHCCEEEEEEEEEEEEECCCHHHHHCCHHHHHHHHH
GVLDYIRQHTHTCYMGVEQGCGECPSCVLREKGLREYLSSKSEAEIDV
HHHHHHHHHCCEEEECHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQLTNPNRDRKAVVIFSGGQDSTTCLFQAIQDYGVENVEVVTFQYGQRHAIELEKAKWIA
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEHHHHHHHH
QDLGVKQTLIDTSVIKAITQNALMDEQARIEQHGSTPNTFVDGRNALFLLYTAIYAKGQG
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHCCCC
IQDIITGVCETDFSGYPDCRDVFIKSMNVTLNLAMDYQFHLKTPLMYLTKAQTWQLADEL
HHHHHHHHHHCCCCCCCCHHHHHHHHCCEEEEEEEEEEEEECCCHHHHHCCHHHHHHHHH
GVLDYIRQHTHTCYMGVEQGCGECPSCVLREKGLREYLSSKSEAEIDV
HHHHHHHHHCCEEEECHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100