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The map label for this gene is lptA [H]

Identifier: 15602037

GI number: 15602037

Start: 197375

End: 197887

Strand: Reverse

Name: lptA [H]

Synonym: PM0172

Alternate gene names: 15602037

Gene position: 197887-197375 (Counterclockwise)

Preceding gene: 15602038

Following gene: 15602036

Centisome position: 8.77

GC content: 38.79

Gene sequence:

>513_bases
ATGAAATCAATAAATAACATTGTCATTTTCACGACATTATTCGCCACCGCATTACCTGCTTTCGCTTTGAAAAGCGATAC
AAAGCAACCGATTAATGTGGTTTCCGATAACCAATCTTTAGACATGGACAACAGCGTGGTAACCTTCACGGATAATGTAG
TTATTACACAAGGCTCTATCCTCATTAAAGCCAGTAAAGTGATCATCACTCGCCCCCCTGAAAATTCTGGTAAAAAAGAC
ACTATCGAAGCCTTTGGTAAGCCGGTGACGTTTTACCAAAAACTTGATGATGGGAAACCTGTAGAAGGGCATGCCAATCA
GGTCCATTATGATCTCACTCAGGAATTTTTAACCTTAACCGGTAATGCAGAACTCAAGCAATTAGACAGCAAAATCAACA
GTGATGTGATTACTTATGATGTCAATAAACAACAATTAAACGCTAACAGCACGCAGGGTTCTCGAGTCAGAACGGTTTTA
ATTCCTACTCAATTAAACGAGAAAAAGAAATAA

Upstream 100 bases:

>100_bases
GTGAAAATTTATGGTCAACATTTTCATTCTACGGGTTTAAAACTCACCGGTAACTTACAACAACAAATCGCGACTTTAAA
AGAGCAGGTAAATACATACT

Downstream 100 bases:

>100_bases
GGTTTTCTATGTCAATTCTTTATGCTGAACATTTAGCAAAAAGCTACAAAAGTCGCCAAGTCGTTTCTGATGTGAGTCTC
ACCGTTAACTCCAATGAAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MKSINNIVIFTTLFATALPAFALKSDTKQPINVVSDNQSLDMDNSVVTFTDNVVITQGSILIKASKVIITRPPENSGKKD
TIEAFGKPVTFYQKLDDGKPVEGHANQVHYDLTQEFLTLTGNAELKQLDSKINSDVITYDVNKQQLNANSTQGSRVRTVL
IPTQLNEKKK

Sequences:

>Translated_170_residues
MKSINNIVIFTTLFATALPAFALKSDTKQPINVVSDNQSLDMDNSVVTFTDNVVITQGSILIKASKVIITRPPENSGKKD
TIEAFGKPVTFYQKLDDGKPVEGHANQVHYDLTQEFLTLTGNAELKQLDSKINSDVITYDVNKQQLNANSTQGSRVRTVL
IPTQLNEKKK
>Mature_170_residues
MKSINNIVIFTTLFATALPAFALKSDTKQPINVVSDNQSLDMDNSVVTFTDNVVITQGSILIKASKVIITRPPENSGKKD
TIEAFGKPVTFYQKLDDGKPVEGHANQVHYDLTQEFLTLTGNAELKQLDSKINSDVITYDVNKQQLNANSTQGSRVRTVL
IPTQLNEKKK

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

Organism=Escherichia coli, GI1789592, Length=163, Percent_Identity=55.2147239263804, Blast_Score=191, Evalue=2e-50,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 18782; Mature: 18782

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSINNIVIFTTLFATALPAFALKSDTKQPINVVSDNQSLDMDNSVVTFTDNVVITQGSI
CCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCEEEEECCEEEECCEE
LIKASKVIITRPPENSGKKDTIEAFGKPVTFYQKLDDGKPVEGHANQVHYDLTQEFLTLT
EEEEEEEEEECCCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCCEEEHHHHHHHEEEC
GNAELKQLDSKINSDVITYDVNKQQLNANSTQGSRVRTVLIPTQLNEKKK
CCCHHHHHHHHCCCCEEEEECCHHHCCCCCCCCCEEEEEEEECCCCCCCC
>Mature Secondary Structure
MKSINNIVIFTTLFATALPAFALKSDTKQPINVVSDNQSLDMDNSVVTFTDNVVITQGSI
CCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCEEEEECCEEEECCEE
LIKASKVIITRPPENSGKKDTIEAFGKPVTFYQKLDDGKPVEGHANQVHYDLTQEFLTLT
EEEEEEEEEECCCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCCEEEHHHHHHHEEEC
GNAELKQLDSKINSDVITYDVNKQQLNANSTQGSRVRTVLIPTQLNEKKK
CCCHHHHHHHHCCCCEEEEECCHHHCCCCCCCCCEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]