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The map label for this gene is fbpB [H]

Identifier: 15601915

GI number: 15601915

Start: 53969

End: 55627

Strand: Reverse

Name: fbpB [H]

Synonym: PM0050

Alternate gene names: 15601915

Gene position: 55627-53969 (Counterclockwise)

Preceding gene: 15601916

Following gene: 15601914

Centisome position: 2.46

GC content: 40.87

Gene sequence:

>1659_bases
ATGTATTCACTCAAAAAAATCAGCTGGAATTTCACCGCACTTTTTATTGTGTTGTTCTTTCTCTTGCCTTTAATTTCTAT
TCTTTATCAATCTTGGCAAGCCGATTGGGACAATATTCAACATCTTTGGCAAACCGTTCTCACCGACTACAGTATCAATT
CGCTCATTTTGGTTTTAGGCACGGTGTTTTTAAGTTTAGTGTTCGCCATTCCCGCCGCGTGGATTATCTCAACTTACCAA
TTTGTCGGACAAAAAACATTGCAATGGGTGCTTTGTTTGCCTTTAGCGATCCCAGCTTATTTAGTCGGCTATCTATACAC
TGATTTATTAGATTATCCCGGTCCGGTACAATCACTTTTACGGGAATACTTTGCTTGGCATAGTCCACAAGATTACTGGT
TCCCGCCAATTCGTTCACTTGGCGGCGCCTGTTTCGTATTAGCACTGGTCTTGTATCCTTATGTATTTTTACTTGTTCGT
GTTGCCTTATTGGAACAATCAGAAAATTTAATTCATAGTGCCAAAACCTTAGGTGCTAGCCGTTTTTACTTATTTAAAAA
AGTCACGTTACCTTTAATCCGTCCAGCCATTGCCGTGGGTGCCTCATTAGTCGCAATGGAAACTCTCGGTGATTTTGGTA
CCGTGTATTATTTTGCGGTGCCGACATTAACTACCGCAGTCTATGATACTTGGCTTGGATATGGTGATTTAGGCTCTGCT
AGCCAAATTTCTTTGTTAATGCTGTTTATGATCTTCAGCTTATTATGGTTAGAACGTTATAGTCGTCGTAAACAAAAAAC
CTATCAACGAGGTTATGAGAAAAAGCGCCGTTTAACGCCTCTTTCTGGTTTCAAACTTGTCCTTGCTCAATTGTATTGTT
GGGGCTTGGTCAGTATCGCCTTCATTATTCCTTTTGCGAAGCTGATTTATTGGGCACTGTCTTATTTTGATATCAGCCAA
GCGGATAACTTTTTCCATTATGCTTATCATAGCTTATCCAGTTCGGTGATCGCTTCTGTTGTATGTGTACTGTTAGCCCT
CTTTCTACACTTTTTTAATCGCCTCGCGTTGCAAAAAAGTCCGATACAGCAGCGTGTTGCACATTATGGCTTACAACTTT
CCTCCCTCGGCTACGCCATACCCGGTACCGTCTTAGCTATTGGGATTCTGATCCCTTATACTCGCGCAGATCATTTACTC
AATGATCTGCTAAAATCCTTTGGCTTTTCCCCTGTTGGTTTAATTTTCTCAGGATCGATGTTTGCTCTCATTTGTGCTTA
TACTGTACGTTTTTCTGCCATGGCAATTGGTGGTATCGATGCCTCGTTTCAAAAAATATCACCTTCCTTAGATATGGCAA
GCCGTACATTAGGTCAAAACGGCATCAAAATGTTACATCGTGTTCATCTGCCATTATTATCTAAAGGTATTCTCACCGCA
TTGATGATGGTGTTTATTGAAACCATGAAAGAATTAAATGCTTCGTTATTATTACGTCCTTTTAATTTTGATACTTTGGC
AACCCATGTTTTTACCTTTACTTCCGATGAGCAGCTCGAACAAGCCGCCCTACCTGCCATTGCGTTGGTGTTAGTCGGCT
TATTGCCGGTGATTTGGTTGACACGCTCACTGGTGCTTCATTCCGAAAAAGATCGCTAA

Upstream 100 bases:

>100_bases
CGAAGTGAAATTCGATCTTTAATTTAGTGACCTGATTTATCTCAACTGGCAAGGGCGACGTTAATGTCGCCCTTTAAATA
TTATTATAGACGACGCTAAG

Downstream 100 bases:

>100_bases
TTATGAATATATTACAAATATCCCAATTAACTTGTGGTTACAGTACCGAAAACGTCTTACAAAACTTAGATCTGGCGATG
GCTCAGAATGAAATTCTCTG

Product: FbpB

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: Iron(III)-transport system permease protein fbpB 2 [H]

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MYSLKKISWNFTALFIVLFFLLPLISILYQSWQADWDNIQHLWQTVLTDYSINSLILVLGTVFLSLVFAIPAAWIISTYQ
FVGQKTLQWVLCLPLAIPAYLVGYLYTDLLDYPGPVQSLLREYFAWHSPQDYWFPPIRSLGGACFVLALVLYPYVFLLVR
VALLEQSENLIHSAKTLGASRFYLFKKVTLPLIRPAIAVGASLVAMETLGDFGTVYYFAVPTLTTAVYDTWLGYGDLGSA
SQISLLMLFMIFSLLWLERYSRRKQKTYQRGYEKKRRLTPLSGFKLVLAQLYCWGLVSIAFIIPFAKLIYWALSYFDISQ
ADNFFHYAYHSLSSSVIASVVCVLLALFLHFFNRLALQKSPIQQRVAHYGLQLSSLGYAIPGTVLAIGILIPYTRADHLL
NDLLKSFGFSPVGLIFSGSMFALICAYTVRFSAMAIGGIDASFQKISPSLDMASRTLGQNGIKMLHRVHLPLLSKGILTA
LMMVFIETMKELNASLLLRPFNFDTLATHVFTFTSDEQLEQAALPAIALVLVGLLPVIWLTRSLVLHSEKDR

Sequences:

>Translated_552_residues
MYSLKKISWNFTALFIVLFFLLPLISILYQSWQADWDNIQHLWQTVLTDYSINSLILVLGTVFLSLVFAIPAAWIISTYQ
FVGQKTLQWVLCLPLAIPAYLVGYLYTDLLDYPGPVQSLLREYFAWHSPQDYWFPPIRSLGGACFVLALVLYPYVFLLVR
VALLEQSENLIHSAKTLGASRFYLFKKVTLPLIRPAIAVGASLVAMETLGDFGTVYYFAVPTLTTAVYDTWLGYGDLGSA
SQISLLMLFMIFSLLWLERYSRRKQKTYQRGYEKKRRLTPLSGFKLVLAQLYCWGLVSIAFIIPFAKLIYWALSYFDISQ
ADNFFHYAYHSLSSSVIASVVCVLLALFLHFFNRLALQKSPIQQRVAHYGLQLSSLGYAIPGTVLAIGILIPYTRADHLL
NDLLKSFGFSPVGLIFSGSMFALICAYTVRFSAMAIGGIDASFQKISPSLDMASRTLGQNGIKMLHRVHLPLLSKGILTA
LMMVFIETMKELNASLLLRPFNFDTLATHVFTFTSDEQLEQAALPAIALVLVGLLPVIWLTRSLVLHSEKDR
>Mature_552_residues
MYSLKKISWNFTALFIVLFFLLPLISILYQSWQADWDNIQHLWQTVLTDYSINSLILVLGTVFLSLVFAIPAAWIISTYQ
FVGQKTLQWVLCLPLAIPAYLVGYLYTDLLDYPGPVQSLLREYFAWHSPQDYWFPPIRSLGGACFVLALVLYPYVFLLVR
VALLEQSENLIHSAKTLGASRFYLFKKVTLPLIRPAIAVGASLVAMETLGDFGTVYYFAVPTLTTAVYDTWLGYGDLGSA
SQISLLMLFMIFSLLWLERYSRRKQKTYQRGYEKKRRLTPLSGFKLVLAQLYCWGLVSIAFIIPFAKLIYWALSYFDISQ
ADNFFHYAYHSLSSSVIASVVCVLLALFLHFFNRLALQKSPIQQRVAHYGLQLSSLGYAIPGTVLAIGILIPYTRADHLL
NDLLKSFGFSPVGLIFSGSMFALICAYTVRFSAMAIGGIDASFQKISPSLDMASRTLGQNGIKMLHRVHLPLLSKGILTA
LMMVFIETMKELNASLLLRPFNFDTLATHVFTFTSDEQLEQAALPAIALVLVGLLPVIWLTRSLVLHSEKDR

Specific function: Part of the ABC transporter complex fbpABC (TC 3.A.1.10.1) involved in Fe(3+) ions import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1178

COG function: function code P; ABC-type Fe3+ transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transmembrane type-1 domains [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=225, Percent_Identity=26.6666666666667, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082099, Length=298, Percent_Identity=25.8389261744966, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786980, Length=232, Percent_Identity=31.8965517241379, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 62283; Mature: 62283

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCCCC
>Mature Secondary Structure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HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 7927717 [H]