Click here to switch to the map view.

The map label for this gene is arcB [H]

Identifier: 15595187

GI number: 15595187

Start: 900796

End: 901782

Strand: Direct

Name: arcB [H]

Synonym: BB0842

Alternate gene names: 15595187

Gene position: 900796-901782 (Clockwise)

Preceding gene: 15595186

Following gene: 15595188

Centisome position: 98.91

GC content: 34.55

Gene sequence:

>987_bases
TTGATGTATAATTTACGAAATAGGAGCTTTTTAAATCTTTTAGATTTTACAAGCAAAGATATTAAATATTTACTTGATTT
ATCGATTAATTTAAAAAAGTCAAAATATGCAGGAATTGAAGTGCAAAAACTTAAAGGTAAAAATATAGTTATAATTTTCG
AGAAAGATTCAACAAGGACCCGGTGTGCTTTTGAGATCGCAGCCTATGATCAAGGGGCAAATATTACTTATTTGGGATCT
AAGGGTAATCAAATGGGCTCAAAAGAGTCTATGATAGATACCGCTAGAGTTTTGGGACGCATGTATGATGCTATTGGATT
TAGAGGCTTTTCTCAACAGACTGTTGAATGTTTGGCGAATTATTCTAATGTTCCTGTTTACAATGGATTGACAGATATTT
CTCACCCAACCCAAATACTAGCCGATTTAATGACAATAAAAGAACATAAGGGGAGTTTGAAAGGGATTAAAATAGTGTTT
TGTGGCGATGGTAGGGGGAATGTTGCTAATTCTTTATTGAAAGGCTGTGCTATTATGGGGCTTGATTTTAGAATTTTTGC
TCCCAAAGAGCTTTTTCCAGACCCCGATTTGACGCTTAAGGCTAGGTCTTTAGCCCTAGAGAGTGGGGGTAAAATTACAA
TTACAGATTCTAAAGAAGAGGCTGTTAAATGTGCTGATGTTGTGTATACAGACGTGTGGGTATCTATGGGGGAGAGTAAT
TGGGAAGATAGAATAAATCTTCTAAAGGCTTATCAGGTTAATAAAGAGATAATGTGCATGGCAAAAGATGATGCAATATT
TATGCATTGCTTGCCTGCTTTTCATGACTTAAACACTGTGATTGGTAAGGATATTTTTGATAAATACGGACTTGATGGAA
TTGAAGTTACAGAAGAAATTTTTGAAAGTAAAAATTCAGTTGTTTTTGATGTGGCTGAAAATAGGGTGCATACCATTAAA
GCTATTATGGTATCAACTTTGGGATAA

Upstream 100 bases:

>100_bases
TGCATGTCTATGTCTTTAGTAAGAGAGGATATTTAATATTTAAGCATGTTTAAGCATGAGTTAAATGAGTTTTTAAAAAC
TTGATTGTAAAGGTTGGTGG

Downstream 100 bases:

>100_bases
CAGTATTTTTTATGTGAAATTAAATTTATGAAATTATTTAGGAGAAACGTTATGATCAAAATGCCAAGTAGTTTTACAAT
AATATTTTCTTTAATTGTAT

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MMYNLRNRSFLNLLDFTSKDIKYLLDLSINLKKSKYAGIEVQKLKGKNIVIIFEKDSTRTRCAFEIAAYDQGANITYLGS
KGNQMGSKESMIDTARVLGRMYDAIGFRGFSQQTVECLANYSNVPVYNGLTDISHPTQILADLMTIKEHKGSLKGIKIVF
CGDGRGNVANSLLKGCAIMGLDFRIFAPKELFPDPDLTLKARSLALESGGKITITDSKEEAVKCADVVYTDVWVSMGESN
WEDRINLLKAYQVNKEIMCMAKDDAIFMHCLPAFHDLNTVIGKDIFDKYGLDGIEVTEEIFESKNSVVFDVAENRVHTIK
AIMVSTLG

Sequences:

>Translated_328_residues
MMYNLRNRSFLNLLDFTSKDIKYLLDLSINLKKSKYAGIEVQKLKGKNIVIIFEKDSTRTRCAFEIAAYDQGANITYLGS
KGNQMGSKESMIDTARVLGRMYDAIGFRGFSQQTVECLANYSNVPVYNGLTDISHPTQILADLMTIKEHKGSLKGIKIVF
CGDGRGNVANSLLKGCAIMGLDFRIFAPKELFPDPDLTLKARSLALESGGKITITDSKEEAVKCADVVYTDVWVSMGESN
WEDRINLLKAYQVNKEIMCMAKDDAIFMHCLPAFHDLNTVIGKDIFDKYGLDGIEVTEEIFESKNSVVFDVAENRVHTIK
AIMVSTLG
>Mature_328_residues
MMYNLRNRSFLNLLDFTSKDIKYLLDLSINLKKSKYAGIEVQKLKGKNIVIIFEKDSTRTRCAFEIAAYDQGANITYLGS
KGNQMGSKESMIDTARVLGRMYDAIGFRGFSQQTVECLANYSNVPVYNGLTDISHPTQILADLMTIKEHKGSLKGIKIVF
CGDGRGNVANSLLKGCAIMGLDFRIFAPKELFPDPDLTLKARSLALESGGKITITDSKEEAVKCADVVYTDVWVSMGESN
WEDRINLLKAYQVNKEIMCMAKDDAIFMHCLPAFHDLNTVIGKDIFDKYGLDGIEVTEEIFESKNSVVFDVAENRVHTIK
AIMVSTLG

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=326, Percent_Identity=38.0368098159509, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI18105007, Length=330, Percent_Identity=23.3333333333333, Blast_Score=85, Evalue=8e-17,
Organism=Escherichia coli, GI1786469, Length=335, Percent_Identity=54.6268656716418, Blast_Score=375, Evalue=1e-105,
Organism=Escherichia coli, GI1790703, Length=332, Percent_Identity=53.3132530120482, Blast_Score=373, Evalue=1e-105,
Organism=Escherichia coli, GI48994908, Length=375, Percent_Identity=26.6666666666667, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI2367364, Length=289, Percent_Identity=28.0276816608997, Blast_Score=80, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322373, Length=285, Percent_Identity=31.9298245614035, Blast_Score=141, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6322331, Length=282, Percent_Identity=27.6595744680851, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24642586, Length=249, Percent_Identity=26.1044176706827, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 36584; Mature: 36584

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMYNLRNRSFLNLLDFTSKDIKYLLDLSINLKKSKYAGIEVQKLKGKNIVIIFEKDSTRT
CEECCCCCCHHHHHHCCCHHHHEEEEEEEEECCCCCCCCEEEEECCCEEEEEEECCCCCC
RCAFEIAAYDQGANITYLGSKGNQMGSKESMIDTARVLGRMYDAIGFRGFSQQTVECLAN
EEEEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
YSNVPVYNGLTDISHPTQILADLMTIKEHKGSLKGIKIVFCGDGRGNVANSLLKGCAIMG
CCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHCC
LDFRIFAPKELFPDPDLTLKARSLALESGGKITITDSKEEAVKCADVVYTDVWVSMGESN
CCEEEECCHHHCCCCCCEEEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCC
WEDRINLLKAYQVNKEIMCMAKDDAIFMHCLPAFHDLNTVIGKDIFDKYGLDGIEVTEEI
HHHHHHHHHHHCCCCEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FESKNSVVFDVAENRVHTIKAIMVSTLG
HCCCCCEEEEECCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MMYNLRNRSFLNLLDFTSKDIKYLLDLSINLKKSKYAGIEVQKLKGKNIVIIFEKDSTRT
CEECCCCCCHHHHHHCCCHHHHEEEEEEEEECCCCCCCCEEEEECCCEEEEEEECCCCCC
RCAFEIAAYDQGANITYLGSKGNQMGSKESMIDTARVLGRMYDAIGFRGFSQQTVECLAN
EEEEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
YSNVPVYNGLTDISHPTQILADLMTIKEHKGSLKGIKIVFCGDGRGNVANSLLKGCAIMG
CCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHCC
LDFRIFAPKELFPDPDLTLKARSLALESGGKITITDSKEEAVKCADVVYTDVWVSMGESN
CCEEEECCHHHCCCCCCEEEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCC
WEDRINLLKAYQVNKEIMCMAKDDAIFMHCLPAFHDLNTVIGKDIFDKYGLDGIEVTEEI
HHHHHHHHHHHCCCCEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FESKNSVVFDVAENRVHTIKAIMVSTLG
HCCCCCEEEEECCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9402027 [H]