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The map label for this gene is cheA

Identifier: 15595014

GI number: 15595014

Start: 706673

End: 709267

Strand: Direct

Name: cheA

Synonym: BB0669

Alternate gene names: 15595014

Gene position: 706673-709267 (Clockwise)

Preceding gene: 15595013

Following gene: 15595015

Centisome position: 77.59

GC content: 28.9

Gene sequence:

>2595_bases
ATGGAAATATTAGATTTGGAAAATGAAGAGCTTTTAGGAGTTTTTTTTGAAGAAGCTCAAAATCTTGTAGATATCCTTGA
AGAGAATATTATGTCATTAGAGGATGATCCTAATAATTCTGATACTATTGATGAAATATTCAGGGCAGCTCATACTTTAA
AAGGAAGCTCTGCTTCTCTTGATATGATGGAGTTATCTGATTTTACCCATATTGTCGAAGATGTTTTTGATGCTATTAGA
GATGGTAAGGTAAATATAAATAATGATCTTGTTGATCTGCTTTTAAGTTCATTAGATGTTATCAAGGAAATGCTTGCGCT
TCGTATTGATGGCAAGGTTTATTTAAATGACATAAGTGATCTTAAAAGCAAATTAAAGCAATTTTTAGTAATTGATGATC
AGACTTTTATTAAGAGATTTGATGGAAATTCAATTAAAAACAATTTTTGTCTTTCAGAATCAGATCTTGAGGAGATAAGA
GAAGGGCTAGGAATTGGACAAAAGGTTTTAAGGATCAGTGTTGTTTTTAATTCAAATAGCAATTCTGAAGTTGAAAATAG
TGGGCTAAAAATATTTAATATTTTAAAAAATTTAGGATCTGTACTTCATACAATTCCTAAATATGAGCAAATCATAGAGG
ATAAATTTTTAAAAAGGGTTGATTATTATCTGATATATTCAGATATAGAAGGCGTGAAAAAAAGTTTAGATTCTTTAAAT
TTAATTGAAAGCTATTTGGTTGATGAATTTAACGTAAAAGAAGAATTAAAAAAGCTTGCAGATGAAGAGATTAAAGATGT
TGATTTAGATTCCAATTTTGTTTTAAATGATAATTTTGATTTTACAGAGGATGAGATTTCTGATTTATTACTTGAGGTTG
AAAATCAAAAGTTATTTAAAGTTAGATTGGATTTTGTAAAAGACAATCCTATGGCTACTATTAGTGGGCTTCAAATGCTT
CAAGCATTAAAAAGTCTTGGTAAAATTTTCAAGTCTATCCCAGATTCTAGCGAATTATTGGCAGATAAGTTTTTTGATTT
TGTAATATATTACTTAATATCAAATACCAGTGAAGAAAGTATTGCTAAAAAGATTAATTTACCAGATGTTGTTAGTCATT
TTGAAATCAAAAATGTTAATTTAGAATCTTTAAAGAGCGTAAGGCTAAAAGAAGATGATGAAGCACCTTTTAAGGAAAAT
AAAAATATTAAGAAAAATAGTCCAATTAGTGTTAATTTAATTAGAATAGATAGCAAAAAAATAGATTACATATTAAATCT
TGTCAGTGAGGCTGTAATAAGTAAATCATCTTATAATCAAATAAATTCAGAAATGATTACATTATTTTATAATTTTAATT
ATTTTTATGATTATCAAGAAAGTTTTCAGAGAAACTTTTTAATTGATTTAAAGATAGTTTTCAAAGATGCAGGCTTAACA
TTAGAAGATGAGATCGAATCACATATTAATTCTTTGATGAGTTTTAAAATGGAAAAGGCTCTTAAGGATATATCTGAATT
GAGAAATTCTTTTTTCAGACTTCTTCAAAATTTTAAAATGACCTCTGGGCGGCTGTCAAGAATAATTACAGATTTGCATG
AGAGTGTTTTAAAAACCAGAATGTTACCAATATCTAATATATTTTCAAGGTTTACAAGAGTCGTAAGAGATCTTTCAAAG
AAATTAAATAAGATTGTGAATCTTAAAATGGAAGGGGAAGAAACTGAGCTTGATAAGTCTGTTATAGATGACCTTGTAGA
TCCTTTGATGCATTGTGTTAGAAATTCAATGGATCATGGCCTTGAAACAGTTGAAGAGAGAGTTAAAAGGGGAAAGAGCA
AAGCAGGTACTATAATTTTGCGTGCCAAGAATGAAGGTAATGTAATATCAATTGAGATTGAAGATGATGGGATTGGTATA
GATCCAAAGGTCATTAGGCGCAAATTAATTGAAAAGGGAACAATAAAAGAAGATGCAATTTACTCTGATTTTGAACTTAT
TAACTTAATTTTTGCTCCTGGGTTTTCAACAGCAGTTCAAGTGACAGACCTTTCAGGTAGAGGAGTTGGTCTTGACGTTG
TGAAAAAAAGCATTGAAAAGCTTAATGGAACTATTTTGGTGGAATCAGAAATTGGTCTTGGAACAATTTTTAAAATTAAA
CTACCATTGACGTTAGTGATTATACAAGGTCTTTTAGTAAAGTCGGGGTCTGAGACTTATGTTATTCCTTTAAATAATGT
TCTTGAAACTCATAGAATAACTGAACATGATATAAAATTGCTTGAAAATTATCATGAAGTTTATAATTTAAGAGATGAAG
TCATTTCTGTTCTCAGGCTTGATAAACTTTTTAACATAACAAGGGATGATTCATTAATAGAAAAATTTTTAATAGTTGTT
AATACTAGCAACATGAAGATAGCAATTGTTGTAGACTCTATTCTTGGTGAGGAAGATTTTGTAGTAAAGCCTATTAAGGA
TAAATTTTCATCAAGCGCGGGTATAGTTGGGGCTACTACGCTTGGCAATGGTAAGGTTGTATTGATAATTGATGTTTTTA
AACTTTTTGATTTACAAAAGGATACTAAGGAGTGA

Upstream 100 bases:

>100_bases
GAAAAACCTGAAGAATCATCTCCGAAAAATTAGGTTTAAATTAATATGTAAAGCTACCTAAAAGGTTTGCTTTACATATT
AAAATAATAGGAAATAGTAT

Downstream 100 bases:

>100_bases
TCTCTTGTGCAGATAAAAGAAATTTATTTTGGACCCAAAATTTTAGATGATAAAAATTCTAATTCTAAATTGACCAATTT
TGATTTTAAAGTTGTTTCTT

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 864; Mature: 864

Protein sequence:

>864_residues
MEILDLENEELLGVFFEEAQNLVDILEENIMSLEDDPNNSDTIDEIFRAAHTLKGSSASLDMMELSDFTHIVEDVFDAIR
DGKVNINNDLVDLLLSSLDVIKEMLALRIDGKVYLNDISDLKSKLKQFLVIDDQTFIKRFDGNSIKNNFCLSESDLEEIR
EGLGIGQKVLRISVVFNSNSNSEVENSGLKIFNILKNLGSVLHTIPKYEQIIEDKFLKRVDYYLIYSDIEGVKKSLDSLN
LIESYLVDEFNVKEELKKLADEEIKDVDLDSNFVLNDNFDFTEDEISDLLLEVENQKLFKVRLDFVKDNPMATISGLQML
QALKSLGKIFKSIPDSSELLADKFFDFVIYYLISNTSEESIAKKINLPDVVSHFEIKNVNLESLKSVRLKEDDEAPFKEN
KNIKKNSPISVNLIRIDSKKIDYILNLVSEAVISKSSYNQINSEMITLFYNFNYFYDYQESFQRNFLIDLKIVFKDAGLT
LEDEIESHINSLMSFKMEKALKDISELRNSFFRLLQNFKMTSGRLSRIITDLHESVLKTRMLPISNIFSRFTRVVRDLSK
KLNKIVNLKMEGEETELDKSVIDDLVDPLMHCVRNSMDHGLETVEERVKRGKSKAGTIILRAKNEGNVISIEIEDDGIGI
DPKVIRRKLIEKGTIKEDAIYSDFELINLIFAPGFSTAVQVTDLSGRGVGLDVVKKSIEKLNGTILVESEIGLGTIFKIK
LPLTLVIIQGLLVKSGSETYVIPLNNVLETHRITEHDIKLLENYHEVYNLRDEVISVLRLDKLFNITRDDSLIEKFLIVV
NTSNMKIAIVVDSILGEEDFVVKPIKDKFSSSAGIVGATTLGNGKVVLIIDVFKLFDLQKDTKE

Sequences:

>Translated_864_residues
MEILDLENEELLGVFFEEAQNLVDILEENIMSLEDDPNNSDTIDEIFRAAHTLKGSSASLDMMELSDFTHIVEDVFDAIR
DGKVNINNDLVDLLLSSLDVIKEMLALRIDGKVYLNDISDLKSKLKQFLVIDDQTFIKRFDGNSIKNNFCLSESDLEEIR
EGLGIGQKVLRISVVFNSNSNSEVENSGLKIFNILKNLGSVLHTIPKYEQIIEDKFLKRVDYYLIYSDIEGVKKSLDSLN
LIESYLVDEFNVKEELKKLADEEIKDVDLDSNFVLNDNFDFTEDEISDLLLEVENQKLFKVRLDFVKDNPMATISGLQML
QALKSLGKIFKSIPDSSELLADKFFDFVIYYLISNTSEESIAKKINLPDVVSHFEIKNVNLESLKSVRLKEDDEAPFKEN
KNIKKNSPISVNLIRIDSKKIDYILNLVSEAVISKSSYNQINSEMITLFYNFNYFYDYQESFQRNFLIDLKIVFKDAGLT
LEDEIESHINSLMSFKMEKALKDISELRNSFFRLLQNFKMTSGRLSRIITDLHESVLKTRMLPISNIFSRFTRVVRDLSK
KLNKIVNLKMEGEETELDKSVIDDLVDPLMHCVRNSMDHGLETVEERVKRGKSKAGTIILRAKNEGNVISIEIEDDGIGI
DPKVIRRKLIEKGTIKEDAIYSDFELINLIFAPGFSTAVQVTDLSGRGVGLDVVKKSIEKLNGTILVESEIGLGTIFKIK
LPLTLVIIQGLLVKSGSETYVIPLNNVLETHRITEHDIKLLENYHEVYNLRDEVISVLRLDKLFNITRDDSLIEKFLIVV
NTSNMKIAIVVDSILGEEDFVVKPIKDKFSSSAGIVGATTLGNGKVVLIIDVFKLFDLQKDTKE
>Mature_864_residues
MEILDLENEELLGVFFEEAQNLVDILEENIMSLEDDPNNSDTIDEIFRAAHTLKGSSASLDMMELSDFTHIVEDVFDAIR
DGKVNINNDLVDLLLSSLDVIKEMLALRIDGKVYLNDISDLKSKLKQFLVIDDQTFIKRFDGNSIKNNFCLSESDLEEIR
EGLGIGQKVLRISVVFNSNSNSEVENSGLKIFNILKNLGSVLHTIPKYEQIIEDKFLKRVDYYLIYSDIEGVKKSLDSLN
LIESYLVDEFNVKEELKKLADEEIKDVDLDSNFVLNDNFDFTEDEISDLLLEVENQKLFKVRLDFVKDNPMATISGLQML
QALKSLGKIFKSIPDSSELLADKFFDFVIYYLISNTSEESIAKKINLPDVVSHFEIKNVNLESLKSVRLKEDDEAPFKEN
KNIKKNSPISVNLIRIDSKKIDYILNLVSEAVISKSSYNQINSEMITLFYNFNYFYDYQESFQRNFLIDLKIVFKDAGLT
LEDEIESHINSLMSFKMEKALKDISELRNSFFRLLQNFKMTSGRLSRIITDLHESVLKTRMLPISNIFSRFTRVVRDLSK
KLNKIVNLKMEGEETELDKSVIDDLVDPLMHCVRNSMDHGLETVEERVKRGKSKAGTIILRAKNEGNVISIEIEDDGIGI
DPKVIRRKLIEKGTIKEDAIYSDFELINLIFAPGFSTAVQVTDLSGRGVGLDVVKKSIEKLNGTILVESEIGLGTIFKIK
LPLTLVIIQGLLVKSGSETYVIPLNNVLETHRITEHDIKLLENYHEVYNLRDEVISVLRLDKLFNITRDDSLIEKFLIVV
NTSNMKIAIVVDSILGEEDFVVKPIKDKFSSSAGIVGATTLGNGKVVLIIDVFKLFDLQKDTKE

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain

Homologues:

Organism=Escherichia coli, GI1788197, Length=343, Percent_Identity=41.9825072886297, Blast_Score=283, Evalue=4e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CHEA_BORBU (Q44737)

Other databases:

- EMBL:   U28962
- EMBL:   AE000783
- EMBL:   U62900
- EMBL:   X91907
- PIR:   D70183
- RefSeq:   NP_212803.1
- ProteinModelPortal:   Q44737
- EnsemblBacteria:   EBBORT00000009103
- GeneID:   1195521
- GenomeReviews:   AE000783_GR
- KEGG:   bbu:BB0669
- NMPDR:   fig|224326.1.peg.1053
- TIGR:   BB_0669
- GeneTree:   EBGT00050000006728
- HOGENOM:   HBG705053
- OMA:   VSHEVHI
- PhylomeDB:   Q44737
- ProtClustDB:   CLSK507748
- BioCyc:   BBUR224326:BB_0669-MONOMER
- BRENDA:   2.7.13.3
- GO:   GO:0005737
- GO:   GO:0006935
- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR010808
- Gene3D:   G3DSA:3.30.565.10
- Gene3D:   G3DSA:1.20.120.160
- Gene3D:   G3DSA:1.10.287.560
- PRINTS:   PR00344
- SMART:   SM00260
- SMART:   SM00387
- SMART:   SM00073

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2; SSF55874 ATP_bd_ATPase; SSF50341 CheW; SSF47226 Hpt

EC number: =2.7.13.3

Molecular weight: Translated: 98354; Mature: 98354

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS50851 CHEW; PS50109 HIS_KIN; PS50894 HPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEILDLENEELLGVFFEEAQNLVDILEENIMSLEDDPNNSDTIDEIFRAAHTLKGSSASL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
DMMELSDFTHIVEDVFDAIRDGKVNINNDLVDLLLSSLDVIKEMLALRIDGKVYLNDISD
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHH
LKSKLKQFLVIDDQTFIKRFDGNSIKNNFCLSESDLEEIREGLGIGQKVLRISVVFNSNS
HHHHHHHHEEECCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEEECCC
NSEVENSGLKIFNILKNLGSVLHTIPKYEQIIEDKFLKRVDYYLIYSDIEGVKKSLDSLN
CCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHH
LIESYLVDEFNVKEELKKLADEEIKDVDLDSNFVLNDNFDFTEDEISDLLLEVENQKLFK
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCEEEE
VRLDFVKDNPMATISGLQMLQALKSLGKIFKSIPDSSELLADKFFDFVIYYLISNTSEES
EEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHH
IAKKINLPDVVSHFEIKNVNLESLKSVRLKEDDEAPFKENKNIKKNSPISVNLIRIDSKK
HHHHCCCCHHHHHCEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCHH
IDYILNLVSEAVISKSSYNQINSEMITLFYNFNYFYDYQESFQRNFLIDLKIVFKDAGLT
HHHHHHHHHHHHHCCCHHHHHCCEEEEEEEECCEEECHHHHHCCCEEEEEEEEEECCCCC
LEDEIESHINSLMSFKMEKALKDISELRNSFFRLLQNFKMTSGRLSRIITDLHESVLKTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
MLPISNIFSRFTRVVRDLSKKLNKIVNLKMEGEETELDKSVIDDLVDPLMHCVRNSMDHG
CCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LETVEERVKRGKSKAGTIILRAKNEGNVISIEIEDDGIGIDPKVIRRKLIEKGTIKEDAI
HHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHH
YSDFELINLIFAPGFSTAVQVTDLSGRGVGLDVVKKSIEKLNGTILVESEIGLGTIFKIK
HHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCCEEEEEE
LPLTLVIIQGLLVKSGSETYVIPLNNVLETHRITEHDIKLLENYHEVYNLRDEVISVLRL
CHHHHHHHHHHHHCCCCCEEEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DKLFNITRDDSLIEKFLIVVNTSNMKIAIVVDSILGEEDFVVKPIKDKFSSSAGIVGATT
HHHHCCCCCHHHHHHEEEEEECCCEEEEEEEECCCCCCCCEECCHHHHCCCCCCCEEEEE
LGNGKVVLIIDVFKLFDLQKDTKE
ECCCCEEEEEEHHHHHCCCCCCCC
>Mature Secondary Structure
MEILDLENEELLGVFFEEAQNLVDILEENIMSLEDDPNNSDTIDEIFRAAHTLKGSSASL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
DMMELSDFTHIVEDVFDAIRDGKVNINNDLVDLLLSSLDVIKEMLALRIDGKVYLNDISD
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHH
LKSKLKQFLVIDDQTFIKRFDGNSIKNNFCLSESDLEEIREGLGIGQKVLRISVVFNSNS
HHHHHHHHEEECCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEEECCC
NSEVENSGLKIFNILKNLGSVLHTIPKYEQIIEDKFLKRVDYYLIYSDIEGVKKSLDSLN
CCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHH
LIESYLVDEFNVKEELKKLADEEIKDVDLDSNFVLNDNFDFTEDEISDLLLEVENQKLFK
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCEEEE
VRLDFVKDNPMATISGLQMLQALKSLGKIFKSIPDSSELLADKFFDFVIYYLISNTSEES
EEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHH
IAKKINLPDVVSHFEIKNVNLESLKSVRLKEDDEAPFKENKNIKKNSPISVNLIRIDSKK
HHHHCCCCHHHHHCEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCHH
IDYILNLVSEAVISKSSYNQINSEMITLFYNFNYFYDYQESFQRNFLIDLKIVFKDAGLT
HHHHHHHHHHHHHCCCHHHHHCCEEEEEEEECCEEECHHHHHCCCEEEEEEEEEECCCCC
LEDEIESHINSLMSFKMEKALKDISELRNSFFRLLQNFKMTSGRLSRIITDLHESVLKTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
MLPISNIFSRFTRVVRDLSKKLNKIVNLKMEGEETELDKSVIDDLVDPLMHCVRNSMDHG
CCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LETVEERVKRGKSKAGTIILRAKNEGNVISIEIEDDGIGIDPKVIRRKLIEKGTIKEDAI
HHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHH
YSDFELINLIFAPGFSTAVQVTDLSGRGVGLDVVKKSIEKLNGTILVESEIGLGTIFKIK
HHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCCEEEEEE
LPLTLVIIQGLLVKSGSETYVIPLNNVLETHRITEHDIKLLENYHEVYNLRDEVISVLRL
CHHHHHHHHHHHHCCCCCEEEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DKLFNITRDDSLIEKFLIVVNTSNMKIAIVVDSILGEEDFVVKPIKDKFSSSAGIVGATT
HHHHCCCCCHHHHHHEEEEEECCCEEEEEEEECCCCCCCCEECCHHHHCCCCCCCEEEEE
LGNGKVVLIIDVFKLFDLQKDTKE
ECCCCEEEEEEHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9765799; 9403685; 8990312