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The map label for this gene is yajL [H]

Identifier: 15594966

GI number: 15594966

Start: 648553

End: 649107

Strand: Direct

Name: yajL [H]

Synonym: BB0621

Alternate gene names: 15594966

Gene position: 648553-649107 (Clockwise)

Preceding gene: 15594964

Following gene: 15594969

Centisome position: 71.21

GC content: 31.89

Gene sequence:

>555_bases
ATGGTAGTAGGAATTATTCTTGCAAATGGCTTTGAAGATATTGAGGCCATAATCCCGATTGATATTTTAAGACGGGGTAA
TGTTAATATTCAAATTATCAGCACAAATGATAGCAATGTTGTGATAAGTTCAAAAGGCGTTTCTTTTTTAGCAGATGATA
TAATATCAAACTGTAAGGAAAATTGTTTTGATCTAATAATTCTCCCGGGAGGTATGCCTGGAGCTACTAATCTTTTTAAT
TCAAAAGAATTGGATTTGATTTTAAAAGATATGAATTCCAAAGGTAAGTTTATTGCAGCTATTTGTGCTTCTCCGGTAGT
AGTGCTTGCTGCTAAAGGTCTTCTAGGATTCAATAAGTTTACATGTTATCCAGGTTTGGAGAAAAATGTGCTTGATGGTG
AGTTTGTAGATGAAAATGTTGTTAGAAGCAATAATTTTATTACTTCTAAAGGAGTTGGAACTTCATTTGAATTTGCTTTT
ACTCTTCTTGAAATGGTAAAAGGAAAACAAATAATGGAAGATGTTAAAAAAGCAACTTTGCTTTGCAAGAGTTAA

Upstream 100 bases:

>100_bases
AATAAAAGTTTAAGCTGATGTAGCTCAGTTGGTTAGAGCACTCGGCTCATATCCGAGTTGTCGTGGGTTCAAGTCCCTCC
ATCAGCATTAGAGGTTGTAA

Downstream 100 bases:

>100_bases
ATATAAATCTATTTTAAATGATTATAATAAATAAACCAGATTTTAGTTTTTAAAATTGTAAATTATAAATTTTTTGGAAT
TAAATTATAAATGTCTTCAA

Product: 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MVVGIILANGFEDIEAIIPIDILRRGNVNIQIISTNDSNVVISSKGVSFLADDIISNCKENCFDLIILPGGMPGATNLFN
SKELDLILKDMNSKGKFIAAICASPVVVLAAKGLLGFNKFTCYPGLEKNVLDGEFVDENVVRSNNFITSKGVGTSFEFAF
TLLEMVKGKQIMEDVKKATLLCKS

Sequences:

>Translated_184_residues
MVVGIILANGFEDIEAIIPIDILRRGNVNIQIISTNDSNVVISSKGVSFLADDIISNCKENCFDLIILPGGMPGATNLFN
SKELDLILKDMNSKGKFIAAICASPVVVLAAKGLLGFNKFTCYPGLEKNVLDGEFVDENVVRSNNFITSKGVGTSFEFAF
TLLEMVKGKQIMEDVKKATLLCKS
>Mature_184_residues
MVVGIILANGFEDIEAIIPIDILRRGNVNIQIISTNDSNVVISSKGVSFLADDIISNCKENCFDLIILPGGMPGATNLFN
SKELDLILKDMNSKGKFIAAICASPVVVLAAKGLLGFNKFTCYPGLEKNVLDGEFVDENVVRSNNFITSKGVGTSFEFAF
TLLEMVKGKQIMEDVKKATLLCKS

Specific function: Involved in biogenesis of ribosomal proteins, probably as a ribosomal protein-folding chaperone. Interacts with ribosomal subunits, ribosomes and polysomes. Confers resistance to oxidative stress [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=182, Percent_Identity=35.7142857142857, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI31543380, Length=182, Percent_Identity=35.7142857142857, Blast_Score=113, Evalue=1e-25,
Organism=Escherichia coli, GI87081736, Length=175, Percent_Identity=31.4285714285714, Blast_Score=100, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17531319, Length=167, Percent_Identity=32.3353293413174, Blast_Score=100, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17558714, Length=174, Percent_Identity=34.4827586206897, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28571932, Length=180, Percent_Identity=35, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24653499, Length=180, Percent_Identity=35, Blast_Score=107, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006287
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 19884; Mature: 19884

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVGIILANGFEDIEAIIPIDILRRGNVNIQIISTNDSNVVISSKGVSFLADDIISNCKE
CEEEEEEECCCHHHHHHCCHHHEECCCCEEEEEEECCCEEEEECCCCHHHHHHHHHHHHH
NCFDLIILPGGMPGATNLFNSKELDLILKDMNSKGKFIAAICASPVVVLAAKGLLGFNKF
CCEEEEEECCCCCCCCCCCCCCCHHHHEECCCCCCCEEEEHHHCCCEEEHHCCCCCCCCE
TCYPGLEKNVLDGEFVDENVVRSNNFITSKGVGTSFEFAFTLLEMVKGKQIMEDVKKATL
EECCCCCCCCCCCCCCCCHHHHCCCEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
LCKS
HCCC
>Mature Secondary Structure
MVVGIILANGFEDIEAIIPIDILRRGNVNIQIISTNDSNVVISSKGVSFLADDIISNCKE
CEEEEEEECCCHHHHHHCCHHHEECCCCEEEEEEECCCEEEEECCCCHHHHHHHHHHHHH
NCFDLIILPGGMPGATNLFNSKELDLILKDMNSKGKFIAAICASPVVVLAAKGLLGFNKF
CCEEEEEECCCCCCCCCCCCCCCHHHHEECCCCCCCEEEEHHHCCCEEEHHCCCCCCCCE
TCYPGLEKNVLDGEFVDENVVRSNNFITSKGVGTSFEFAFTLLEMVKGKQIMEDVKKATL
EECCCCCCCCCCCCCCCCHHHHCCCEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
LCKS
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9592144 [H]