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The map label for this gene is mtnN [H]

Identifier: 15594933

GI number: 15594933

Start: 607138

End: 607935

Strand: Direct

Name: mtnN [H]

Synonym: BB0588

Alternate gene names: 15594933

Gene position: 607138-607935 (Clockwise)

Preceding gene: 15594930

Following gene: 15594934

Centisome position: 66.67

GC content: 30.7

Gene sequence:

>798_bases
ATGAATAATTGTTTAATAAAGTTTTTTATTTTTTTATTAGTTTTTTCAAACAGTTATGTTGCTTTTTCTAAAAATGTCAA
TGTTTTAATAGTAACTGCTATGGACTCTGAGTTTGATCAGATAAATAAGCTTATGTCTAATAAGGAAGAAATAGTTCTTA
AGGAGTATGGTCTTAATAAAAAGATTTTAAAGGGGAAGTTGTCTAATCGCAATGTTATGGTTATTATTTGTGGGGTTGGT
AAGGTTAATGCTGGTGTGTGGACTAGCTACATTTTGTCAAAATACAACATAAGTCATGTCATTAATTCTGGCGTTGCTGG
TGGCGTTGTTAGTGCTAAATACAAAGATATTAAAGTGGGAGATGTGGTGGTGTCTTCAGAGGTTGCATATCATGATGTTG
ATTTGACTAAATTTGGATACAAGGTAGGACAGCTTACAGGAGGATTGCCTCAAAAATTTAATGCCAATAAAAATTTAATT
AAGAATGCCATAGAGGCCATTAAATCAAAGGTTGGAGGTTCTAATGCATATTCAGGATTAATAGTTTCAGGAGATCAGTT
TATTGATCCAACTTATATTAACAAAATTATAGGAAACTTTAAAGATGTAATAGCTGTTGAGATGGAAGGTGCAGCAATAG
GGCATGTTTCTCATATGTTTAATATACCTTTTATAGTTATTAGGTCAATATCTGACATTGTAAATAAAGAAGGGAATGAG
GTTGAATATAGTAAATTTTCTAAAATAGCTGCTTTCAATTCAGCCAAAGTTGTACAAGAAATTTTAAGAAAACTTTAA

Upstream 100 bases:

>100_bases
TTTCAATATCTTTTACAAAAATTCTTTCAAAAGCAATTCAATTTTGGCTTTTTTGTAAAAAATGATATAAATATTCTTTT
ATTATAAGGAGTGTGATTTT

Downstream 100 bases:

>100_bases
GAAATATTTAATTTTTATAATTGAAAATCATGTATGAAAAAAGATTTTTTATTTTAAAATGTCTTTTTTTATGCATTATC
AATTGTGTTGTATTCTTTTT

Product: pfs protein

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MNNCLIKFFIFLLVFSNSYVAFSKNVNVLIVTAMDSEFDQINKLMSNKEEIVLKEYGLNKKILKGKLSNRNVMVIICGVG
KVNAGVWTSYILSKYNISHVINSGVAGGVVSAKYKDIKVGDVVVSSEVAYHDVDLTKFGYKVGQLTGGLPQKFNANKNLI
KNAIEAIKSKVGGSNAYSGLIVSGDQFIDPTYINKIIGNFKDVIAVEMEGAAIGHVSHMFNIPFIVIRSISDIVNKEGNE
VEYSKFSKIAAFNSAKVVQEILRKL

Sequences:

>Translated_265_residues
MNNCLIKFFIFLLVFSNSYVAFSKNVNVLIVTAMDSEFDQINKLMSNKEEIVLKEYGLNKKILKGKLSNRNVMVIICGVG
KVNAGVWTSYILSKYNISHVINSGVAGGVVSAKYKDIKVGDVVVSSEVAYHDVDLTKFGYKVGQLTGGLPQKFNANKNLI
KNAIEAIKSKVGGSNAYSGLIVSGDQFIDPTYINKIIGNFKDVIAVEMEGAAIGHVSHMFNIPFIVIRSISDIVNKEGNE
VEYSKFSKIAAFNSAKVVQEILRKL
>Mature_265_residues
MNNCLIKFFIFLLVFSNSYVAFSKNVNVLIVTAMDSEFDQINKLMSNKEEIVLKEYGLNKKILKGKLSNRNVMVIICGVG
KVNAGVWTSYILSKYNISHVINSGVAGGVVSAKYKDIKVGDVVVSSEVAYHDVDLTKFGYKVGQLTGGLPQKFNANKNLI
KNAIEAIKSKVGGSNAYSGLIVSGDQFIDPTYINKIIGNFKDVIAVEMEGAAIGHVSHMFNIPFIVIRSISDIVNKEGNE
VEYSKFSKIAAFNSAKVVQEILRKL

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=237, Percent_Identity=38.8185654008439, Blast_Score=137, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 29088; Mature: 29088

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNCLIKFFIFLLVFSNSYVAFSKNVNVLIVTAMDSEFDQINKLMSNKEEIVLKEYGLNK
CCCHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCHHHHHHHHCCCHHEEHHHCCCCH
KILKGKLSNRNVMVIICGVGKVNAGVWTSYILSKYNISHVINSGVAGGVVSAKYKDIKVG
HHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEC
DVVVSSEVAYHDVDLTKFGYKVGQLTGGLPQKFNANKNLIKNAIEAIKSKVGGSNAYSGL
CEEEECCCEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCE
IVSGDQFIDPTYINKIIGNFKDVIAVEMEGAAIGHVSHMFNIPFIVIRSISDIVNKEGNE
EECCCCCCCHHHHHHHHCCHHHEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCE
VEYSKFSKIAAFNSAKVVQEILRKL
EHHHHHHHHHHCCHHHHHHHHHHHC
>Mature Secondary Structure
MNNCLIKFFIFLLVFSNSYVAFSKNVNVLIVTAMDSEFDQINKLMSNKEEIVLKEYGLNK
CCCHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCHHHHHHHHCCCHHEEHHHCCCCH
KILKGKLSNRNVMVIICGVGKVNAGVWTSYILSKYNISHVINSGVAGGVVSAKYKDIKVG
HHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEC
DVVVSSEVAYHDVDLTKFGYKVGQLTGGLPQKFNANKNLIKNAIEAIKSKVGGSNAYSGL
CEEEECCCEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCE
IVSGDQFIDPTYINKIIGNFKDVIAVEMEGAAIGHVSHMFNIPFIVIRSISDIVNKEGNE
EECCCCCCCHHHHHHHHCCHHHEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCE
VEYSKFSKIAAFNSAKVVQEILRKL
EHHHHHHHHHHCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA