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The map label for this gene is trxB

Identifier: 15594860

GI number: 15594860

Start: 526325

End: 527305

Strand: Direct

Name: trxB

Synonym: BB0515

Alternate gene names: 15594860

Gene position: 526325-527305 (Clockwise)

Preceding gene: 15594859

Following gene: 15594866

Centisome position: 57.79

GC content: 32.42

Gene sequence:

>981_bases
ATGTTGGAATTTGAAACTATTGATATAAATCTAACCAAGAAGAAAAATCTATCTCAAAAAGAGGTAGATTTTATTGAAGA
TGTAATAATTGTAGGATCTGGCCCGGCTGGACTAACAGCTGGGATTTATTCTGTTATGAGTAATTATAAGGCTGCTATTT
TGGAAGGTCCTGAACCCGGGGGACAGCTTACTACAACCACAGAAGTTTACAATTATCCTGGCTTTAAAAATGGAATAAGT
GGTAGAAATTTGATGTTAAATATGAGGGAGCAAGTAGTAAATCTTGGGGCTAAAACTTTTCCCGAAACCGTTTTTTCTAT
AAAAAGGAAGGGTAATATTTTTTACCTTTATACAGAAAATTATATTTATAAAAGTAAAGCTGTTATTATTGCTGTGGGAT
CAAAACCCAAAAAACTTGAAACTCTTAAAAATTCGGGTTTATTTTGGAATAAAGGTATTTCTGTTTGTGCTATTTGTGAT
GGACATCTTTTTAAAGGGAAAAGGGTTGCAGTAATTGGTGGAGGCAACACTGCCCTTTCAGAATCAATTTATTTAAGCAA
ATTGGTGGACAAGGTTTATCTTATTGTAAGAAAAAATAATCTTAGAGCTATTGCTATGTTAAGAGATAGTGTTGCTAAGT
TACCTAATATTGAAATTTTGTATAATTCAGAAGCCATAGAAGTAGATGGTAAATCTTCTGTTTCTTCGGTTAAGATTTTT
AATAAAAAAGATAATGTTGTTTATGAATTAGAAGTGAGTGCTGTATTTATGGCTGTTGGCTATAAGCCAAATACAGAATT
TTTAAAGGGATTTTTGGATTTGGACGAAGAGGGATTTATTGTCACTAAAGATGTTGTTAAAACAAGCGTTGATGGTGTTT
TTTCATGTGGAGATGTTAGCAATAAACTTTATGCTCAAGCCATTACTGCTGCTGCTGAGGGGTTTATTGCATCTGTTGAG
TTAGGAAATTTTTTAAAATAG

Upstream 100 bases:

>100_bases
AATATAAACAAACTTATGAGTCGATCTTAAGCATTGAATATTAGTTTTAGCAATGTTAAGATTAATATTCAAATTTTTAA
GAGAGGCCTGAAGTTTAGAT

Downstream 100 bases:

>100_bases
TTTTTATTAAGATGTTTTTGTTTTTTTAAATGAAGTTTTTATATAATTTAATGCTTTAGAGTAGATTTAATTGTCTTTTG
ATTTCAAAAATTAAAATGCC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MLEFETIDINLTKKKNLSQKEVDFIEDVIIVGSGPAGLTAGIYSVMSNYKAAILEGPEPGGQLTTTTEVYNYPGFKNGIS
GRNLMLNMREQVVNLGAKTFPETVFSIKRKGNIFYLYTENYIYKSKAVIIAVGSKPKKLETLKNSGLFWNKGISVCAICD
GHLFKGKRVAVIGGGNTALSESIYLSKLVDKVYLIVRKNNLRAIAMLRDSVAKLPNIEILYNSEAIEVDGKSSVSSVKIF
NKKDNVVYELEVSAVFMAVGYKPNTEFLKGFLDLDEEGFIVTKDVVKTSVDGVFSCGDVSNKLYAQAITAAAEGFIASVE
LGNFLK

Sequences:

>Translated_326_residues
MLEFETIDINLTKKKNLSQKEVDFIEDVIIVGSGPAGLTAGIYSVMSNYKAAILEGPEPGGQLTTTTEVYNYPGFKNGIS
GRNLMLNMREQVVNLGAKTFPETVFSIKRKGNIFYLYTENYIYKSKAVIIAVGSKPKKLETLKNSGLFWNKGISVCAICD
GHLFKGKRVAVIGGGNTALSESIYLSKLVDKVYLIVRKNNLRAIAMLRDSVAKLPNIEILYNSEAIEVDGKSSVSSVKIF
NKKDNVVYELEVSAVFMAVGYKPNTEFLKGFLDLDEEGFIVTKDVVKTSVDGVFSCGDVSNKLYAQAITAAAEGFIASVE
LGNFLK
>Mature_326_residues
MLEFETIDINLTKKKNLSQKEVDFIEDVIIVGSGPAGLTAGIYSVMSNYKAAILEGPEPGGQLTTTTEVYNYPGFKNGIS
GRNLMLNMREQVVNLGAKTFPETVFSIKRKGNIFYLYTENYIYKSKAVIIAVGSKPKKLETLKNSGLFWNKGISVCAICD
GHLFKGKRVAVIGGGNTALSESIYLSKLVDKVYLIVRKNNLRAIAMLRDSVAKLPNIEILYNSEAIEVDGKSSVSSVKIF
NKKDNVVYELEVSAVFMAVGYKPNTEFLKGFLDLDEEGFIVTKDVVKTSVDGVFSCGDVSNKLYAQAITAAAEGFIASVE
LGNFLK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family

Homologues:

Organism=Escherichia coli, GI1787114, Length=309, Percent_Identity=36.8932038834951, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI87081763, Length=304, Percent_Identity=31.25, Blast_Score=135, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6320560, Length=311, Percent_Identity=40.1929260450161, Blast_Score=220, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6321898, Length=311, Percent_Identity=39.2282958199357, Blast_Score=219, Evalue=6e-58,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRXB_BORBU (P94284)

Other databases:

- EMBL:   U82978
- EMBL:   AE000783
- PIR:   B70164
- RefSeq:   NP_212649.1
- ProteinModelPortal:   P94284
- SMR:   P94284
- EnsemblBacteria:   EBBORT00000009090
- GeneID:   1195361
- GenomeReviews:   AE000783_GR
- KEGG:   bbu:BB0515
- NMPDR:   fig|224326.1.peg.899
- TIGR:   BB_0515
- GeneTree:   EBGT00050000006911
- HOGENOM:   HBG669726
- OMA:   PSCGPCH
- ProtClustDB:   CLSK507629
- BioCyc:   BBUR224326:BB_0515-MONOMER
- BRENDA:   1.8.1.9
- GO:   GO:0005737
- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982
- PRINTS:   PR00368
- PRINTS:   PR00469
- TIGRFAMs:   TIGR01292

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2

EC number: =1.8.1.9

Molecular weight: Translated: 35674; Mature: 35674

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEFETIDINLTKKKNLSQKEVDFIEDVIIVGSGPAGLTAGIYSVMSNYKAAILEGPEPG
CCEEEEEEEEEECCCCCCHHHHHHHEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCC
GQLTTTTEVYNYPGFKNGISGRNLMLNMREQVVNLGAKTFPETVFSIKRKGNIFYLYTEN
CCEEEEEEEECCCCCCCCCCCCCEEEEHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECC
YIYKSKAVIIAVGSKPKKLETLKNSGLFWNKGISVCAICDGHLFKGKRVAVIGGGNTALS
EEEECCEEEEEECCCCHHHHHHHCCCEEEECCCEEEEEECCCEECCCEEEEEECCCCHHH
ESIYLSKLVDKVYLIVRKNNLRAIAMLRDSVAKLPNIEILYNSEAIEVDGKSSVSSVKIF
HHHHHHHHHHHEEEEEECCCCEEEEEEHHHHHHCCCEEEEECCCEEEECCCCCCCEEEEE
NKKDNVVYELEVSAVFMAVGYKPNTEFLKGFLDLDEEGFIVTKDVVKTSVDGVFSCGDVS
ECCCCEEEEEEEEEEEEEECCCCCHHHHHHHHCCCCCCEEEEHHHHHHHHCCEEECCCCC
NKLYAQAITAAAEGFIASVELGNFLK
HHHHHHHHHHHHCCEEEEEECCCCCC
>Mature Secondary Structure
MLEFETIDINLTKKKNLSQKEVDFIEDVIIVGSGPAGLTAGIYSVMSNYKAAILEGPEPG
CCEEEEEEEEEECCCCCCHHHHHHHEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCC
GQLTTTTEVYNYPGFKNGISGRNLMLNMREQVVNLGAKTFPETVFSIKRKGNIFYLYTEN
CCEEEEEEEECCCCCCCCCCCCCEEEEHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECC
YIYKSKAVIIAVGSKPKKLETLKNSGLFWNKGISVCAICDGHLFKGKRVAVIGGGNTALS
EEEECCEEEEEECCCCHHHHHHHCCCEEEECCCEEEEEECCCEECCCEEEEEECCCCHHH
ESIYLSKLVDKVYLIVRKNNLRAIAMLRDSVAKLPNIEILYNSEAIEVDGKSSVSSVKIF
HHHHHHHHHHHEEEEEECCCCEEEEEEHHHHHHCCCEEEEECCCEEEECCCCCCCEEEEE
NKKDNVVYELEVSAVFMAVGYKPNTEFLKGFLDLDEEGFIVTKDVVKTSVDGVFSCGDVS
ECCCCEEEEEEEEEEEEEECCCCCHHHHHHHHCCCCCCEEEEHHHHHHHHCCEEECCCCC
NKLYAQAITAAAEGFIASVELGNFLK
HHHHHHHHHHHHCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685