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The map label for this gene is idsA [H]

Identifier: 15594659

GI number: 15594659

Start: 320309

End: 321352

Strand: Direct

Name: idsA [H]

Synonym: BB0314

Alternate gene names: 15594659

Gene position: 320309-321352 (Clockwise)

Preceding gene: 15594608

Following gene: 15594660

Centisome position: 35.17

GC content: 24.62

Gene sequence:

>1044_bases
ATGCAAAATAAACTATTTTTAAAAAATATTGAAAAAAATATTAATAAAATCTTTTCAACAACTAATTTTCTAAATTTATT
CAAAGATAACGATTTAAAATTTACTTTTAAAATAAAAAAGGAAACCCTTGATTATATTAAAGCACCAGCAATTGAAATTG
TTAATAGGGGCGGAAAACGAATAAGACCAATGATAATGATTCTTTTAGCATATGCATTGGGTTTAAAAGAAAAAAATACC
AAACTAATATATAAATTAAGCTTGCTGCTTGAACTTCCTCATTCTGGAAGCTTGATTATTGATGACATTGAAGACAATTC
ACTAAAAAGACGCGGTGCATCAGCAATACATTTAATCTATGGAATAGATAACAGTATAAATGCTGGCAATTTAATTTATT
TTTTACCTGCAAAATTAATAGAAAAATCAAATTTAAAAGAAAATCAAAAATTATTAATTTATGAAAATTTCTTTACAACT
CTTTCAAATCTCCACCTAGGACAAGGAATTGATATTAAATTTCACAATGAGTCATACATCCCAAGTATTAAAGAATACAT
CTCTTTAGTAGAATTAAAAACAGCTTCACTTTTTGGAATGGCCAGCTTTCTAGCTGCAATACTCACAAATAATGAAGACA
AAGCTAAAAAAATTTACAGTACATTTTTAAAGCTTGGTGTTTATTTCCAAATAATAGACGATATTAAAAACATTAAAAAT
AAAATTAATGGTAAAGAATTCGGAGATGATTTACTCGAAGGGAAAAAAAGTTTGCCAATAATTTATTTTTTACAAGAAAA
AAAGTTTGAACCAAAAATTATTTCAAAATTCAATCAAATAAAAAATACCAAAACTACCAAAGCAAGAAAAGAAATATTTA
AACTAACAGAAATGATAAACTCATCAAAATCAATAAAAAATTCAACTATTGTTGCCTTAAAATACTTAAACGAGTTTAAA
AACGAACTCAATTTATACCCACTAACAAATAGATATAAAAATCTACTAATAGATACTATTGAGCAAATAAAAGAAGGAAT
ATAA

Upstream 100 bases:

>100_bases
TATCCTTCTCTTTTGGCTTTTTTAGAATATTCATCATCCAAGCGATACACATCAATCCCTTTAATACACTTTATTATACT
TTTTCATTATAATTCTTATT

Downstream 100 bases:

>100_bases
TGAGAAAAATAACAATAATGATACTTTTCTATGGCTTGATAATAAATGTTTGCCCTACTACAACAACATCAATATTAAAA
CTTAATAAAAAAGCAAACAA

Product: octaprenyl-diphosphate synthase

Products: NA

Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MQNKLFLKNIEKNINKIFSTTNFLNLFKDNDLKFTFKIKKETLDYIKAPAIEIVNRGGKRIRPMIMILLAYALGLKEKNT
KLIYKLSLLLELPHSGSLIIDDIEDNSLKRRGASAIHLIYGIDNSINAGNLIYFLPAKLIEKSNLKENQKLLIYENFFTT
LSNLHLGQGIDIKFHNESYIPSIKEYISLVELKTASLFGMASFLAAILTNNEDKAKKIYSTFLKLGVYFQIIDDIKNIKN
KINGKEFGDDLLEGKKSLPIIYFLQEKKFEPKIISKFNQIKNTKTTKARKEIFKLTEMINSSKSIKNSTIVALKYLNEFK
NELNLYPLTNRYKNLLIDTIEQIKEGI

Sequences:

>Translated_347_residues
MQNKLFLKNIEKNINKIFSTTNFLNLFKDNDLKFTFKIKKETLDYIKAPAIEIVNRGGKRIRPMIMILLAYALGLKEKNT
KLIYKLSLLLELPHSGSLIIDDIEDNSLKRRGASAIHLIYGIDNSINAGNLIYFLPAKLIEKSNLKENQKLLIYENFFTT
LSNLHLGQGIDIKFHNESYIPSIKEYISLVELKTASLFGMASFLAAILTNNEDKAKKIYSTFLKLGVYFQIIDDIKNIKN
KINGKEFGDDLLEGKKSLPIIYFLQEKKFEPKIISKFNQIKNTKTTKARKEIFKLTEMINSSKSIKNSTIVALKYLNEFK
NELNLYPLTNRYKNLLIDTIEQIKEGI
>Mature_347_residues
MQNKLFLKNIEKNINKIFSTTNFLNLFKDNDLKFTFKIKKETLDYIKAPAIEIVNRGGKRIRPMIMILLAYALGLKEKNT
KLIYKLSLLLELPHSGSLIIDDIEDNSLKRRGASAIHLIYGIDNSINAGNLIYFLPAKLIEKSNLKENQKLLIYENFFTT
LSNLHLGQGIDIKFHNESYIPSIKEYISLVELKTASLFGMASFLAAILTNNEDKAKKIYSTFLKLGVYFQIIDDIKNIKN
KINGKEFGDDLLEGKKSLPIIYFLQEKKFEPKIISKFNQIKNTKTTKARKEIFKLTEMINSSKSIKNSTIVALKYLNEFK
NELNLYPLTNRYKNLLIDTIEQIKEGI

Specific function: Supplies Octaprenyl Diphosphate, The Precursor For The Side Chain Of The Isoprenoid Quinones Ubiquinone And Menaquinone. [C]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI4758430, Length=212, Percent_Identity=35.377358490566, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI83700220, Length=212, Percent_Identity=35.377358490566, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI50659086, Length=283, Percent_Identity=24.3816254416961, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1789578, Length=225, Percent_Identity=32.4444444444444, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17505681, Length=240, Percent_Identity=26.25, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325188, Length=278, Percent_Identity=30.9352517985612, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281365769, Length=265, Percent_Identity=29.4339622641509, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24660002, Length=265, Percent_Identity=29.4339622641509, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24651612, Length=270, Percent_Identity=22.962962962963, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.1; =2.5.1.10 [H]

Molecular weight: Translated: 39993; Mature: 39993

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS00052 RIBOSOMAL_S7 ; PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNKLFLKNIEKNINKIFSTTNFLNLFKDNDLKFTFKIKKETLDYIKAPAIEIVNRGGKR
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHCCHHHHHHCCCCH
IRPMIMILLAYALGLKEKNTKLIYKLSLLLELPHSGSLIIDDIEDNSLKRRGASAIHLIY
HHHHHHHHHHHHHCCCCCCCEEEEEEEEHHCCCCCCCEEEECCCCCHHHHCCCCEEEEEE
GIDNSINAGNLIYFLPAKLIEKSNLKENQKLLIYENFFTTLSNLHLGQGIDIKFHNESYI
ECCCCCCCCCEEEECCHHHHHHCCCCCCCEEEEEHHHHHHHHHCCCCCCCEEEECCCCCC
PSIKEYISLVELKTASLFGMASFLAAILTNNEDKAKKIYSTFLKLGVYFQIIDDIKNIKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KINGKEFGDDLLEGKKSLPIIYFLQEKKFEPKIISKFNQIKNTKTTKARKEIFKLTEMIN
HCCCHHCCHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
SSKSIKNSTIVALKYLNEFKNELNLYPLTNRYKNLLIDTIEQIKEGI
CCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQNKLFLKNIEKNINKIFSTTNFLNLFKDNDLKFTFKIKKETLDYIKAPAIEIVNRGGKR
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHCCHHHHHHCCCCH
IRPMIMILLAYALGLKEKNTKLIYKLSLLLELPHSGSLIIDDIEDNSLKRRGASAIHLIY
HHHHHHHHHHHHHCCCCCCCEEEEEEEEHHCCCCCCCEEEECCCCCHHHHCCCCEEEEEE
GIDNSINAGNLIYFLPAKLIEKSNLKENQKLLIYENFFTTLSNLHLGQGIDIKFHNESYI
ECCCCCCCCCEEEECCHHHHHHCCCCCCCEEEEEHHHHHHHHHCCCCCCCEEEECCCCCC
PSIKEYISLVELKTASLFGMASFLAAILTNNEDKAKKIYSTFLKLGVYFQIIDDIKNIKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KINGKEFGDDLLEGKKSLPIIYFLQEKKFEPKIISKFNQIKNTKTTKARKEIFKLTEMIN
HCCCHHCCHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
SSKSIKNSTIVALKYLNEFKNELNLYPLTNRYKNLLIDTIEQIKEGI
CCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]