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The map label for this gene is degP [H]

Identifier: 154248688

GI number: 154248688

Start: 5296501

End: 5297991

Strand: Reverse

Name: degP [H]

Synonym: Xaut_4771

Alternate gene names: 154248688

Gene position: 5297991-5296501 (Counterclockwise)

Preceding gene: 154248689

Following gene: 154248687

Centisome position: 99.79

GC content: 70.89

Gene sequence:

>1491_bases
ATGAAACGACAGTTCGCATTCACGCTCCTTCTGCTGTGCTCCGCCGCCGTGGGGGCGGCTGCCATGGCGGCCGGCGCGGG
GCCGGGTGAAGCGCCCGCGCGCGCCGCCAGCGTCCCGCTCCGGGTCGAGGCGCAGGCGCAGATCCAACCGCAGGTGCCGG
CCTCCGCCGCCGAGGTGAAGCTCTCGTTTGCGCCCATCGTGGCGCGCACCGCGCCGGCGGTGGTCAATGTCTATGCCCAG
AAGGCCGCCCAGCAGCGGGCCAATCCCATTTTCGACGACCCGTTCTTCCGCCGGTTCTTCGGCGGCCAGGGTGGCCCCGG
CCTGCGCGCGCCGGAGCGGGTGCAGCGCTCCCTGGGGTCGGGGGTGGTGGTGGACCCCTCGGGCATCGTGGTCACCAATT
TCCATGTCATCGAGGGGGCGGACGAGATCCGCATCGCCCTCAACGACCGGCGCGAATACGAGGCAGAAGTGCTGCTGCGC
GACCAGCGCACTGACCTTGCCGTGCTCCGCATCAAGACCGAGGCCAAGGAGACCTTCGCGTCCATCGAGCTCGGCAATTC
GGACGAACTGGCCGTGGGCGACCTGGCGCTGGCCATCGGCGATCCCTTCGGCGTCGGCCAGACGGTGACGCAGGGCATCA
TCTCCGCGCTGGCGCGGACCCAGGTGGGGATCTCCGACTACCAGTTCTTCATCCAGACCGACGCGGCGATCAATCCCGGC
AATTCCGGCGGTGCGCTGGTGGACATGGCGGGCCGGCTGGTGGGCATCAACAGCGCCATCTATTCGCGCTCGGGCGGCTC
CATCGGCATCGGCTTCGCCATTCCGGTGAACATGGTGCGGGTGGTGGTGGAGCAGGCCAAGGGCGGCTCCAAGTCGGTGC
GCCGGCCCTGGCTCGGGGCAAAGCTCCAGCGGGTCACGCCCGACATCGCCGAAAGCCTCGGCCTGCCGCGTCCCACCGGT
GTGCTGGTGCAGGACGTGGTGGCCCACAGCCCGGCCGCCAAGGCGGGCCTCAGGCTGGGGGACCTCATCGTCGCGGTGGA
GGGGCAGCCCATCGACGACCCCGAGTCCCTCAACTACCGCTTCGCCACCCGGCCCATCGGCGGCAAGGCGGCGCTGGCGG
TCAACCGCGGCGGCAAGGAGGTGAGCCTCGTGGTGGTGCTGGAGGGCGCGCCGGAGACCGTACCGCGCGACGAACTGGTG
GTGCGTGCCCGCTCGCCCTTCACCGGCGCCACGGTGGTGAACCTGTCACCGGCGGTGGCCGAGGAACTGAAGGTGGATGC
CAACGCCACCGGCGTGGTGATCTACGACGTGGACGACAATTCCCCCGCCGCCGCCGCCGGCTTCAAGCCCGGCGACGTGC
TGGTCGAGGTGAACGGCGAGAAGGTCGCCCGGACCCGCGACCTGGAGCAGATGGTTCGCACGCCGCTCCGGGCCTGGCGG
GTGACGGTGGGCCGCGCCGGGCGCACCATCACCGCTCTGCTGCCGGGCTGA

Upstream 100 bases:

>100_bases
AGGCGGGGCGGGATGCTCCGGCCACAGGCGTTAGGACGACCATTGGCTGCCGCGCCCGGTTCAGCCGGGCGGGCTTGGCT
TTGAATTACGGGTTCAAGCG

Downstream 100 bases:

>100_bases
GTCGCCTTGGCTCTGCGCCCTGAGTGACCCTCGCCGCCGCCGGTCGCAGGCGGGGCGGGGGCTTGAAACCTGACCGAGAG
GACGAGAGACAACGCCCATG

Product: protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MKRQFAFTLLLLCSAAVGAAAMAAGAGPGEAPARAASVPLRVEAQAQIQPQVPASAAEVKLSFAPIVARTAPAVVNVYAQ
KAAQQRANPIFDDPFFRRFFGGQGGPGLRAPERVQRSLGSGVVVDPSGIVVTNFHVIEGADEIRIALNDRREYEAEVLLR
DQRTDLAVLRIKTEAKETFASIELGNSDELAVGDLALAIGDPFGVGQTVTQGIISALARTQVGISDYQFFIQTDAAINPG
NSGGALVDMAGRLVGINSAIYSRSGGSIGIGFAIPVNMVRVVVEQAKGGSKSVRRPWLGAKLQRVTPDIAESLGLPRPTG
VLVQDVVAHSPAAKAGLRLGDLIVAVEGQPIDDPESLNYRFATRPIGGKAALAVNRGGKEVSLVVVLEGAPETVPRDELV
VRARSPFTGATVVNLSPAVAEELKVDANATGVVIYDVDDNSPAAAAGFKPGDVLVEVNGEKVARTRDLEQMVRTPLRAWR
VTVGRAGRTITALLPG

Sequences:

>Translated_496_residues
MKRQFAFTLLLLCSAAVGAAAMAAGAGPGEAPARAASVPLRVEAQAQIQPQVPASAAEVKLSFAPIVARTAPAVVNVYAQ
KAAQQRANPIFDDPFFRRFFGGQGGPGLRAPERVQRSLGSGVVVDPSGIVVTNFHVIEGADEIRIALNDRREYEAEVLLR
DQRTDLAVLRIKTEAKETFASIELGNSDELAVGDLALAIGDPFGVGQTVTQGIISALARTQVGISDYQFFIQTDAAINPG
NSGGALVDMAGRLVGINSAIYSRSGGSIGIGFAIPVNMVRVVVEQAKGGSKSVRRPWLGAKLQRVTPDIAESLGLPRPTG
VLVQDVVAHSPAAKAGLRLGDLIVAVEGQPIDDPESLNYRFATRPIGGKAALAVNRGGKEVSLVVVLEGAPETVPRDELV
VRARSPFTGATVVNLSPAVAEELKVDANATGVVIYDVDDNSPAAAAGFKPGDVLVEVNGEKVARTRDLEQMVRTPLRAWR
VTVGRAGRTITALLPG
>Mature_496_residues
MKRQFAFTLLLLCSAAVGAAAMAAGAGPGEAPARAASVPLRVEAQAQIQPQVPASAAEVKLSFAPIVARTAPAVVNVYAQ
KAAQQRANPIFDDPFFRRFFGGQGGPGLRAPERVQRSLGSGVVVDPSGIVVTNFHVIEGADEIRIALNDRREYEAEVLLR
DQRTDLAVLRIKTEAKETFASIELGNSDELAVGDLALAIGDPFGVGQTVTQGIISALARTQVGISDYQFFIQTDAAINPG
NSGGALVDMAGRLVGINSAIYSRSGGSIGIGFAIPVNMVRVVVEQAKGGSKSVRRPWLGAKLQRVTPDIAESLGLPRPTG
VLVQDVVAHSPAAKAGLRLGDLIVAVEGQPIDDPESLNYRFATRPIGGKAALAVNRGGKEVSLVVVLEGAPETVPRDELV
VRARSPFTGATVVNLSPAVAEELKVDANATGVVIYDVDDNSPAAAAGFKPGDVLVEVNGEKVARTRDLEQMVRTPLRAWR
VTVGRAGRTITALLPG

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=357, Percent_Identity=30.812324929972, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI24308541, Length=290, Percent_Identity=33.448275862069, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI7019477, Length=342, Percent_Identity=33.6257309941521, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI4506141, Length=347, Percent_Identity=29.3948126801153, Blast_Score=133, Evalue=5e-31,
Organism=Escherichia coli, GI1789629, Length=465, Percent_Identity=36.3440860215054, Blast_Score=251, Evalue=6e-68,
Organism=Escherichia coli, GI1786356, Length=461, Percent_Identity=33.8394793926247, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1789630, Length=346, Percent_Identity=36.1271676300578, Blast_Score=179, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24646839, Length=257, Percent_Identity=33.852140077821, Blast_Score=128, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 51900; Mature: 51900

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRQFAFTLLLLCSAAVGAAAMAAGAGPGEAPARAASVPLRVEAQAQIQPQVPASAAEVK
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCEEEEECCEECCCCCCCHHEEE
LSFAPIVARTAPAVVNVYAQKAAQQRANPIFDDPFFRRFFGGQGGPGLRAPERVQRSLGS
EEEHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHCC
GVVVDPSGIVVTNFHVIEGADEIRIALNDRREYEAEVLLRDQRTDLAVLRIKTEAKETFA
CEEECCCCEEEEEEEEEECCCEEEEEECCCCCCEEEEEEECCCCCEEEEEEECHHHHHHE
SIELGNSDELAVGDLALAIGDPFGVGQTVTQGIISALARTQVGISDYQFFIQTDAAINPG
EEECCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCEECCC
NSGGALVDMAGRLVGINSAIYSRSGGSIGIGFAIPVNMVRVVVEQAKGGSKSVRRPWLGA
CCCCCCEEECCEEEEECHHHEECCCCCEEEEEHHHHHHHHHHHHHHCCCCCHHCCCCCCC
KLQRVTPDIAESLGLPRPTGVLVQDVVAHSPAAKAGLRLGDLIVAVEGQPIDDPESLNYR
HHHHCCHHHHHHCCCCCCCCHHHHHHHHCCCHHHHCCEEEEEEEEECCCCCCCCCCCCEE
FATRPIGGKAALAVNRGGKEVSLVVVLEGAPETVPRDELVVRARSPFTGATVVNLSPAVA
EEECCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCEEEEECCCCCCEEEEECCHHHH
EELKVDANATGVVIYDVDDNSPAAAAGFKPGDVLVEVNGEKVARTRDLEQMVRTPLRAWR
HHHEECCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHE
VTVGRAGRTITALLPG
EEECCCCCEEEEECCC
>Mature Secondary Structure
MKRQFAFTLLLLCSAAVGAAAMAAGAGPGEAPARAASVPLRVEAQAQIQPQVPASAAEVK
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCEEEEECCEECCCCCCCHHEEE
LSFAPIVARTAPAVVNVYAQKAAQQRANPIFDDPFFRRFFGGQGGPGLRAPERVQRSLGS
EEEHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHCC
GVVVDPSGIVVTNFHVIEGADEIRIALNDRREYEAEVLLRDQRTDLAVLRIKTEAKETFA
CEEECCCCEEEEEEEEEECCCEEEEEECCCCCCEEEEEEECCCCCEEEEEEECHHHHHHE
SIELGNSDELAVGDLALAIGDPFGVGQTVTQGIISALARTQVGISDYQFFIQTDAAINPG
EEECCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCEECCC
NSGGALVDMAGRLVGINSAIYSRSGGSIGIGFAIPVNMVRVVVEQAKGGSKSVRRPWLGA
CCCCCCEEECCEEEEECHHHEECCCCCEEEEEHHHHHHHHHHHHHHCCCCCHHCCCCCCC
KLQRVTPDIAESLGLPRPTGVLVQDVVAHSPAAKAGLRLGDLIVAVEGQPIDDPESLNYR
HHHHCCHHHHHHCCCCCCCCHHHHHHHHCCCHHHHCCEEEEEEEEECCCCCCCCCCCCEE
FATRPIGGKAALAVNRGGKEVSLVVVLEGAPETVPRDELVVRARSPFTGATVVNLSPAVA
EEECCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCEEEEECCCCCCEEEEECCHHHH
EELKVDANATGVVIYDVDDNSPAAAAGFKPGDVLVEVNGEKVARTRDLEQMVRTPLRAWR
HHHEECCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHE
VTVGRAGRTITALLPG
EEECCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]