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The map label for this gene is argS

Identifier: 154248165

GI number: 154248165

Start: 4708557

End: 4710317

Strand: Direct

Name: argS

Synonym: Xaut_4245

Alternate gene names: 154248165

Gene position: 4708557-4710317 (Clockwise)

Preceding gene: 154248164

Following gene: 154248166

Centisome position: 88.69

GC content: 67.69

Gene sequence:

>1761_bases
ATGAACGTCTACGCGATCTTCGCCGATCACGTGCGCGAAGCCGTCGCCGCCCTCGTCGCCGAGGGCATCATCGCCAAGGA
CCTCGATCTTGCCCGCGTGGTCGTCGAGCCGCCGCGCGACGCGAGCCACGGCGATCTCGCCACCAACGCCGCCATGGTGC
TGGCCAAGGATGCCGGCCTGAAGCCCCGCGAGCTGGCCGAGCGCATCGCCGGCAAGCTGGGGACGGTGGCGGGCGTGAAA
AAGGTGGATGTGGCCGGCCCCGGCTTCATCAACATCGCGCTGGACGGCACGTTCTGGCCGGTGGTGCTCGCCGCCGTGCT
CACGCAGGGGCTGGATTTCGGCCGCTCGGCGCTGGGCGCGGGCGAGAAGGTGAACGTGGAATATGTCTCCGCCAACCCCA
CCGGTCCCATGCATGTGGGCCATTGCCGGGGCGCGGTGTTCGGCGATGCGCTGGCGCGCCTCATGGATTTTGCCGGCTTC
GCCGTGACCAAGGAATATTACATCAACGACGCCGGCGCCCAGGTGGACGTGCTGGCCCGCTCAGCCTTCCTGCGCTACCG
CGAGGCGCTGGGCGAGGCCATCGGCGAGATCCCCGAAGGCCTCTATCCGGGCGACTATCTGGTGCCGGTGGGGCAGAAGC
TGGCCGCCGCGCACGGCCCGGCGCTCAAGGAGAAGAGCGAGACGGACTGGCTGCCGCTGGTGCGGGCCGAGGCCATCGCG
ACCATGATGGTGGCGATCCGCGAGGATCTGGCGGCGCTGGGCATCTCCTTCGACGTGTTCTTCTCCGAACGCTCGCTCTC
CACCGGCGCGGTGGATCGCGTGGGCGCCGCCATCGAGGCGCTGCGCGCGTCGGGGGAGGTTTATGAGGGCCGCCTGCCGC
CGCCCAAGGGCGCGCCCATCGAGGATTGGGAGGATCGCGAGCAGACCCTGTTCCGCTCCACCGATTTCGGCGACGACGTG
GACCGGCCGCTGAAGAAGTCGGACGGCAGCTACACCTATTTCGCCGGCGACATCGCCTATCACAAGGACAAGGTGGACCG
CGGCTTCCTGAAGATGATCGACGTGTGGGGCGCCGACCACGGCGGCTACGTCAAGCGCATGCAGGCGGCGGTAAAGGCGG
TATCCGGCGGCCGGGCGACGCTGGACGTGGAGCTGATCCAGCTGGTGCGCCTGTTCCGCGCCGGGGAGCCGGTGCGCATG
TCCAAGCGCTCGGGCTCCTTCGTCACCCTGCGCGAGGTGGTGGACGAGGTGGGGCGCGACGCGGTCCGCTTCATGATGCT
GTTCCGCAAGAACGACGCCCCGCTGGACTTCGATCTCGCCAAGGTGATCGAGCAGTCGCGTGAAAACCCGGTATTTTACG
TGCAATATGCGCACGCGCGGGCGAAGTCGATCCTGCGCAACGCGGCCGAGGAATTCGCCGACCTGCCGCAGCAGGCGGCG
TCTTTCGCGACCGCGCCCTTGGCCCGACTCGACGACGAGGGGGAAATCACGCTGCTGCGCCGGCTCGCGAGCTGGCCGCG
CCTCGTGGAGCAGGCGGCGGGAGCGCGGGAGCCGCACCGCATCTCGTTCTTCCTGCACGAACTCGCCAGCGAGTTTCACG
GCCAGTGGAACCGTGGAAAGGACTTGCCTCATTTACGCTTCATTATCGAGAATGATCGAGAGTTGACCTCGGCTCGCTTG
GCCTTGGTCCATGGCGTGGCCACGGTGCTCGCCTCCGGTCTCAAGGTTCTGGGGGTGACGGCCGTAGACGAGATGAAATG
A

Upstream 100 bases:

>100_bases
TGACCGACCGCTACGCCCTCGACCAGCACGCCCGTTTCTTTGACTTGACGCCGGACTTGCGTTAGGCGCCGGGCCAACCA
ACCCGATCGGACCCCGCCCC

Downstream 100 bases:

>100_bases
TCGCTTGTCCCGTGGCTGCGGACGGAGCGGTTGGCCCACCGGGCTAGACTTCTCGGCGCGGTCTTCAATCCGCAGGTTCA
CGGGCGGCGACAACACATCG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 586; Mature: 586

Protein sequence:

>586_residues
MNVYAIFADHVREAVAALVAEGIIAKDLDLARVVVEPPRDASHGDLATNAAMVLAKDAGLKPRELAERIAGKLGTVAGVK
KVDVAGPGFINIALDGTFWPVVLAAVLTQGLDFGRSALGAGEKVNVEYVSANPTGPMHVGHCRGAVFGDALARLMDFAGF
AVTKEYYINDAGAQVDVLARSAFLRYREALGEAIGEIPEGLYPGDYLVPVGQKLAAAHGPALKEKSETDWLPLVRAEAIA
TMMVAIREDLAALGISFDVFFSERSLSTGAVDRVGAAIEALRASGEVYEGRLPPPKGAPIEDWEDREQTLFRSTDFGDDV
DRPLKKSDGSYTYFAGDIAYHKDKVDRGFLKMIDVWGADHGGYVKRMQAAVKAVSGGRATLDVELIQLVRLFRAGEPVRM
SKRSGSFVTLREVVDEVGRDAVRFMMLFRKNDAPLDFDLAKVIEQSRENPVFYVQYAHARAKSILRNAAEEFADLPQQAA
SFATAPLARLDDEGEITLLRRLASWPRLVEQAAGAREPHRISFFLHELASEFHGQWNRGKDLPHLRFIIENDRELTSARL
ALVHGVATVLASGLKVLGVTAVDEMK

Sequences:

>Translated_586_residues
MNVYAIFADHVREAVAALVAEGIIAKDLDLARVVVEPPRDASHGDLATNAAMVLAKDAGLKPRELAERIAGKLGTVAGVK
KVDVAGPGFINIALDGTFWPVVLAAVLTQGLDFGRSALGAGEKVNVEYVSANPTGPMHVGHCRGAVFGDALARLMDFAGF
AVTKEYYINDAGAQVDVLARSAFLRYREALGEAIGEIPEGLYPGDYLVPVGQKLAAAHGPALKEKSETDWLPLVRAEAIA
TMMVAIREDLAALGISFDVFFSERSLSTGAVDRVGAAIEALRASGEVYEGRLPPPKGAPIEDWEDREQTLFRSTDFGDDV
DRPLKKSDGSYTYFAGDIAYHKDKVDRGFLKMIDVWGADHGGYVKRMQAAVKAVSGGRATLDVELIQLVRLFRAGEPVRM
SKRSGSFVTLREVVDEVGRDAVRFMMLFRKNDAPLDFDLAKVIEQSRENPVFYVQYAHARAKSILRNAAEEFADLPQQAA
SFATAPLARLDDEGEITLLRRLASWPRLVEQAAGAREPHRISFFLHELASEFHGQWNRGKDLPHLRFIIENDRELTSARL
ALVHGVATVLASGLKVLGVTAVDEMK
>Mature_586_residues
MNVYAIFADHVREAVAALVAEGIIAKDLDLARVVVEPPRDASHGDLATNAAMVLAKDAGLKPRELAERIAGKLGTVAGVK
KVDVAGPGFINIALDGTFWPVVLAAVLTQGLDFGRSALGAGEKVNVEYVSANPTGPMHVGHCRGAVFGDALARLMDFAGF
AVTKEYYINDAGAQVDVLARSAFLRYREALGEAIGEIPEGLYPGDYLVPVGQKLAAAHGPALKEKSETDWLPLVRAEAIA
TMMVAIREDLAALGISFDVFFSERSLSTGAVDRVGAAIEALRASGEVYEGRLPPPKGAPIEDWEDREQTLFRSTDFGDDV
DRPLKKSDGSYTYFAGDIAYHKDKVDRGFLKMIDVWGADHGGYVKRMQAAVKAVSGGRATLDVELIQLVRLFRAGEPVRM
SKRSGSFVTLREVVDEVGRDAVRFMMLFRKNDAPLDFDLAKVIEQSRENPVFYVQYAHARAKSILRNAAEEFADLPQQAA
SFATAPLARLDDEGEITLLRRLASWPRLVEQAAGAREPHRISFFLHELASEFHGQWNRGKDLPHLRFIIENDRELTSARL
ALVHGVATVLASGLKVLGVTAVDEMK

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=624, Percent_Identity=26.1217948717949, Blast_Score=134, Evalue=2e-31,
Organism=Escherichia coli, GI1788184, Length=630, Percent_Identity=25.8730158730159, Blast_Score=125, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71985061, Length=602, Percent_Identity=24.4186046511628, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71985068, Length=564, Percent_Identity=24.290780141844, Blast_Score=102, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6320548, Length=568, Percent_Identity=24.6478873239437, Blast_Score=110, Evalue=5e-25,
Organism=Drosophila melanogaster, GI18859963, Length=607, Percent_Identity=22.7347611202636, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_XANP2 (A7IN73)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001419123.1
- ProteinModelPortal:   A7IN73
- STRING:   A7IN73
- GeneID:   5423271
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_4245
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   FFAMRSS
- ProtClustDB:   PRK01611
- BioCyc:   XAUT78245:XAUT_4245-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 63746; Mature: 63746

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVYAIFADHVREAVAALVAEGIIAKDLDLARVVVEPPRDASHGDLATNAAMVLAKDAGL
CCEEEEHHHHHHHHHHHHHHHCHHHCCCHHHHEEECCCCCCCCCCHHHCCEEEEEECCCC
KPRELAERIAGKLGTVAGVKKVDVAGPGFINIALDGTFWPVVLAAVLTQGLDFGRSALGA
CHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCCHHHHHHHHHHHHCHHHCHHHHCC
GEKVNVEYVSANPTGPMHVGHCRGAVFGDALARLMDFAGFAVTKEYYINDAGAQVDVLAR
CCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEHHHEECCCCCHHHHHHH
SAFLRYREALGEAIGEIPEGLYPGDYLVPVGQKLAAAHGPALKEKSETDWLPLVRAEAIA
HHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
TMMVAIREDLAALGISFDVFFSERSLSTGAVDRVGAAIEALRASGEVYEGRLPPPKGAPI
HHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCC
EDWEDREQTLFRSTDFGDDVDRPLKKSDGSYTYFAGDIAYHKDKVDRGFLKMIDVWGADH
CCCCCHHHHHHHCCCCCCCCCCHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCC
GGYVKRMQAAVKAVSGGRATLDVELIQLVRLFRAGEPVRMSKRSGSFVTLREVVDEVGRD
CHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCEECCCCCCEEEHHHHHHHHHHH
AVRFMMLFRKNDAPLDFDLAKVIEQSRENPVFYVQYAHARAKSILRNAAEEFADLPQQAA
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCHHHHH
SFATAPLARLDDEGEITLLRRLASWPRLVEQAAGAREPHRISFFLHELASEFHGQWNRGK
HHHHCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCC
DLPHLRFIIENDRELTSARLALVHGVATVLASGLKVLGVTAVDEMK
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHEEECHHHCCC
>Mature Secondary Structure
MNVYAIFADHVREAVAALVAEGIIAKDLDLARVVVEPPRDASHGDLATNAAMVLAKDAGL
CCEEEEHHHHHHHHHHHHHHHCHHHCCCHHHHEEECCCCCCCCCCHHHCCEEEEEECCCC
KPRELAERIAGKLGTVAGVKKVDVAGPGFINIALDGTFWPVVLAAVLTQGLDFGRSALGA
CHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCCHHHHHHHHHHHHCHHHCHHHHCC
GEKVNVEYVSANPTGPMHVGHCRGAVFGDALARLMDFAGFAVTKEYYINDAGAQVDVLAR
CCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEHHHEECCCCCHHHHHHH
SAFLRYREALGEAIGEIPEGLYPGDYLVPVGQKLAAAHGPALKEKSETDWLPLVRAEAIA
HHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
TMMVAIREDLAALGISFDVFFSERSLSTGAVDRVGAAIEALRASGEVYEGRLPPPKGAPI
HHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCC
EDWEDREQTLFRSTDFGDDVDRPLKKSDGSYTYFAGDIAYHKDKVDRGFLKMIDVWGADH
CCCCCHHHHHHHCCCCCCCCCCHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCC
GGYVKRMQAAVKAVSGGRATLDVELIQLVRLFRAGEPVRMSKRSGSFVTLREVVDEVGRD
CHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCEECCCCCCEEEHHHHHHHHHHH
AVRFMMLFRKNDAPLDFDLAKVIEQSRENPVFYVQYAHARAKSILRNAAEEFADLPQQAA
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCHHHHH
SFATAPLARLDDEGEITLLRRLASWPRLVEQAAGAREPHRISFFLHELASEFHGQWNRGK
HHHHCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCC
DLPHLRFIIENDRELTSARLALVHGVATVLASGLKVLGVTAVDEMK
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHEEECHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA