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The map label for this gene is ureC

Identifier: 154248077

GI number: 154248077

Start: 4598838

End: 4600550

Strand: Direct

Name: ureC

Synonym: Xaut_4156

Alternate gene names: 154248077

Gene position: 4598838-4600550 (Clockwise)

Preceding gene: 154248076

Following gene: 154248078

Centisome position: 86.62

GC content: 67.02

Gene sequence:

>1713_bases
ATGTCCTCCTCCAAGATGCCCCGCGCCGCCTATGCCCACATGTTCGGCCCCACCGTGGGCGACAAGGTGCGGCTTGCCGA
TACGCAGCTCTTCATCGAGATCGAGAAGGATTTCACCATCCATGGCGAGGAGGTGAAGTTCGGCGGCGGCAAGGTCATCC
GCGACGGCATGGGCCAGTCGCAGGTGGCGAACGCCGACGGGGCGGTGGACACCGTCATCACCAATGCGGTGGTGCTGGAC
CACTGGGGTGTGGTGAAGGCCGACGTGGGCCTCAAGAACGGCCGCATCGTCCGCCTCGGCAAGGCCGGCAATCCCGATGT
GCAGAACGGGGTGGACATCATCATCGGCCCCGGCACCGAGGTGATCGCGGGGGAGGGCAAGATCCTCACCGCCGGCGGCT
TCGACAGCCATATCCATTTCATCTGCCCGCAGCAGATCGAGGAGGCGCTGGCCTCCGGCGTCACCACCATGCTGGGCGGC
GGCACGGGACCTGCCACCGGCACCTTCGCCACCACTTGCACGCCGGGGCCGTGGCACATCGCCCGCATGATCGAGGCGGC
CGATTCCTTCCCCGTGAACCTCGCCTTCGCCGGCAAGGGCAACGCCTCGCTGCCCGCCGCGCTGGAAGAGATGGTGCTGG
CCGGCGCCTGCGCCCTGAAGCTCCACGAGGACTGGGGCACCACGCCCTCGGCCATCGATTGCTGCCTCTCGGTGGCGGAT
GCGCTGGACGTGCAGGTGATGATCCACACCGACACGCTCAACGAGAGCGGCTTCGTGGAGGACACCATCGCCGCCTTCAA
GGGCCGCACCATCCACGCCTTCCACACCGAAGGGGCGGGCGGCGGGCATGCGCCGGACATCATCAAGGTGGCGGGGCTGG
CGAACGTGCTGCCCTCCTCCACCAATCCGACCCGGCCCTATACCCGCAACACCATCGACGAGCATCTGGACATGCTCATG
GTGTGCCACCACCTCGACCCGGAGATCGCCGAGGACCTCGCCTTCGCCGAGAGCCGCATCCGCAAGGAGACCATCGCGGC
GGAGGACATCCTCCACGACCTCGGCGCGCTCTCCATGATGAGCTCGGACAGTCAGGCCATGGGCCGGGTGGGCGAGGTGA
TCATCCGCACCTGGCAGACAGCGGACAAGATGAAGCGTCAGCGCGGCAAGCTGCCTGGCGAGCGCGACAGCGACAACCTG
CGGGCGCGGCGCTACATCGCCAAATACACCATCAACCCCGCCATCGCCCACGGCATGTCGCGCCATATCGGCTCGGTGGA
GGCCGGCAAGCTCGCCGACCTTGTGCTGTGGACGCCGGCCTTCTTCGGGGTGAAGCCGGATCTGGTCATCAAGGGCGGCG
CCATCGCCATGGCGCAGATGGGCGATCCCAACGCCTCCATTCCCACACCGCAGCCGGTGCATTACCGGCCCATGTTCGGC
GCCTACGGGCGGGCGCTGACCCACACCTCGCTCACCTTCGTCTCGAAATCGGCGATCGAGGACGGGCTCGCCTCCCGCCT
CGGCATCCAGAAGGAACTGGTGGCGGTGGAGAACACGCGCTCCGGCATCTCCAAGAAGAGCATGATCAACAATGACGCCA
CCCCGGTGATCGAGGTGGACCCGGAAACCTACGACGTGCGCGCCGACGGCGAGCTGCTGGTGTGCGAGCCGGCCGAGGTG
CTGCCCATGGCCCAGCGCTATTTCCTGTTCTGA

Upstream 100 bases:

>100_bases
GTTGTAAGCGCGCGAAGGTGTGAGCGCCCCTTGCCGGCTCCGCTCGCTCGTTTCCGCCCGCCCGTTTCTGCCGGTATGAT
TTCCTGAAGGCGATTGCCCC

Downstream 100 bases:

>100_bases
CGAGAGGCGAGAAAGAATTCGCGCGCGGCGGAACCTATGCCATGGCTGGTAGCTTCTAGCGGGTGTTGCAACTCTTTTTG
ATTGAGGAGCCACCCCATGT

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha [H]

Number of amino acids: Translated: 570; Mature: 569

Protein sequence:

>570_residues
MSSSKMPRAAYAHMFGPTVGDKVRLADTQLFIEIEKDFTIHGEEVKFGGGKVIRDGMGQSQVANADGAVDTVITNAVVLD
HWGVVKADVGLKNGRIVRLGKAGNPDVQNGVDIIIGPGTEVIAGEGKILTAGGFDSHIHFICPQQIEEALASGVTTMLGG
GTGPATGTFATTCTPGPWHIARMIEAADSFPVNLAFAGKGNASLPAALEEMVLAGACALKLHEDWGTTPSAIDCCLSVAD
ALDVQVMIHTDTLNESGFVEDTIAAFKGRTIHAFHTEGAGGGHAPDIIKVAGLANVLPSSTNPTRPYTRNTIDEHLDMLM
VCHHLDPEIAEDLAFAESRIRKETIAAEDILHDLGALSMMSSDSQAMGRVGEVIIRTWQTADKMKRQRGKLPGERDSDNL
RARRYIAKYTINPAIAHGMSRHIGSVEAGKLADLVLWTPAFFGVKPDLVIKGGAIAMAQMGDPNASIPTPQPVHYRPMFG
AYGRALTHTSLTFVSKSAIEDGLASRLGIQKELVAVENTRSGISKKSMINNDATPVIEVDPETYDVRADGELLVCEPAEV
LPMAQRYFLF

Sequences:

>Translated_570_residues
MSSSKMPRAAYAHMFGPTVGDKVRLADTQLFIEIEKDFTIHGEEVKFGGGKVIRDGMGQSQVANADGAVDTVITNAVVLD
HWGVVKADVGLKNGRIVRLGKAGNPDVQNGVDIIIGPGTEVIAGEGKILTAGGFDSHIHFICPQQIEEALASGVTTMLGG
GTGPATGTFATTCTPGPWHIARMIEAADSFPVNLAFAGKGNASLPAALEEMVLAGACALKLHEDWGTTPSAIDCCLSVAD
ALDVQVMIHTDTLNESGFVEDTIAAFKGRTIHAFHTEGAGGGHAPDIIKVAGLANVLPSSTNPTRPYTRNTIDEHLDMLM
VCHHLDPEIAEDLAFAESRIRKETIAAEDILHDLGALSMMSSDSQAMGRVGEVIIRTWQTADKMKRQRGKLPGERDSDNL
RARRYIAKYTINPAIAHGMSRHIGSVEAGKLADLVLWTPAFFGVKPDLVIKGGAIAMAQMGDPNASIPTPQPVHYRPMFG
AYGRALTHTSLTFVSKSAIEDGLASRLGIQKELVAVENTRSGISKKSMINNDATPVIEVDPETYDVRADGELLVCEPAEV
LPMAQRYFLF
>Mature_569_residues
SSSKMPRAAYAHMFGPTVGDKVRLADTQLFIEIEKDFTIHGEEVKFGGGKVIRDGMGQSQVANADGAVDTVITNAVVLDH
WGVVKADVGLKNGRIVRLGKAGNPDVQNGVDIIIGPGTEVIAGEGKILTAGGFDSHIHFICPQQIEEALASGVTTMLGGG
TGPATGTFATTCTPGPWHIARMIEAADSFPVNLAFAGKGNASLPAALEEMVLAGACALKLHEDWGTTPSAIDCCLSVADA
LDVQVMIHTDTLNESGFVEDTIAAFKGRTIHAFHTEGAGGGHAPDIIKVAGLANVLPSSTNPTRPYTRNTIDEHLDMLMV
CHHLDPEIAEDLAFAESRIRKETIAAEDILHDLGALSMMSSDSQAMGRVGEVIIRTWQTADKMKRQRGKLPGERDSDNLR
ARRYIAKYTINPAIAHGMSRHIGSVEAGKLADLVLWTPAFFGVKPDLVIKGGAIAMAQMGDPNASIPTPQPVHYRPMFGA
YGRALTHTSLTFVSKSAIEDGLASRLGIQKELVAVENTRSGISKKSMINNDATPVIEVDPETYDVRADGELLVCEPAEVL
PMAQRYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950 [H]

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha [H]

EC number: =3.5.1.5 [H]

Molecular weight: Translated: 60791; Mature: 60660

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00145 UREASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSKMPRAAYAHMFGPTVGDKVRLADTQLFIEIEKDFTIHGEEVKFGGGKVIRDGMGQS
CCCCCCCHHHHHHHHCCCCCCEEEEECEEEEEEEECCEEEECCEEEECCCEEEECCCCCC
QVANADGAVDTVITNAVVLDHWGVVKADVGLKNGRIVRLGKAGNPDVQNGVDIIIGPGTE
CCCCCCCCHHHHHHCEEEEECCCEEEECCCCCCCCEEEECCCCCCCCCCCCEEEECCCCE
VIAGEGKILTAGGFDSHIHFICPQQIEEALASGVTTMLGGGTGPATGTFATTCTPGPWHI
EEECCCEEEEECCCCCCEEEECHHHHHHHHHCCCHHHHCCCCCCCCCCEEECCCCCHHHH
ARMIEAADSFPVNLAFAGKGNASLPAALEEMVLAGACALKLHEDWGTTPSAIDCCLSVAD
HHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHH
ALDVQVMIHTDTLNESGFVEDTIAAFKGRTIHAFHTEGAGGGHAPDIIKVAGLANVLPSS
CCEEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCC
TNPTRPYTRNTIDEHLDMLMVCHHLDPEIAEDLAFAESRIRKETIAAEDILHDLGALSMM
CCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSDSQAMGRVGEVIIRTWQTADKMKRQRGKLPGERDSDNLRARRYIAKYTINPAIAHGMS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHEECCHHHHHHHH
RHIGSVEAGKLADLVLWTPAFFGVKPDLVIKGGAIAMAQMGDPNASIPTPQPVHYRPMFG
HHCCCCCCCCHHHHEEECHHHHCCCCCEEEECCEEEEEECCCCCCCCCCCCCCEECCCHH
AYGRALTHTSLTFVSKSAIEDGLASRLGIQKELVAVENTRSGISKKSMINNDATPVIEVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEECCHHCCCCHHHHCCCCCCCEEEEC
PETYDVRADGELLVCEPAEVLPMAQRYFLF
CCEEEEECCCCEEEECCHHHHHHHHHHHCC
>Mature Secondary Structure 
SSSKMPRAAYAHMFGPTVGDKVRLADTQLFIEIEKDFTIHGEEVKFGGGKVIRDGMGQS
CCCCCCHHHHHHHHCCCCCCEEEEECEEEEEEEECCEEEECCEEEECCCEEEECCCCCC
QVANADGAVDTVITNAVVLDHWGVVKADVGLKNGRIVRLGKAGNPDVQNGVDIIIGPGTE
CCCCCCCCHHHHHHCEEEEECCCEEEECCCCCCCCEEEECCCCCCCCCCCCEEEECCCCE
VIAGEGKILTAGGFDSHIHFICPQQIEEALASGVTTMLGGGTGPATGTFATTCTPGPWHI
EEECCCEEEEECCCCCCEEEECHHHHHHHHHCCCHHHHCCCCCCCCCCEEECCCCCHHHH
ARMIEAADSFPVNLAFAGKGNASLPAALEEMVLAGACALKLHEDWGTTPSAIDCCLSVAD
HHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHH
ALDVQVMIHTDTLNESGFVEDTIAAFKGRTIHAFHTEGAGGGHAPDIIKVAGLANVLPSS
CCEEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCC
TNPTRPYTRNTIDEHLDMLMVCHHLDPEIAEDLAFAESRIRKETIAAEDILHDLGALSMM
CCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSDSQAMGRVGEVIIRTWQTADKMKRQRGKLPGERDSDNLRARRYIAKYTINPAIAHGMS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHEECCHHHHHHHH
RHIGSVEAGKLADLVLWTPAFFGVKPDLVIKGGAIAMAQMGDPNASIPTPQPVHYRPMFG
HHCCCCCCCCHHHHEEECHHHHCCCCCEEEECCEEEEEECCCCCCCCCCCCCCEECCCHH
AYGRALTHTSLTFVSKSAIEDGLASRLGIQKELVAVENTRSGISKKSMINNDATPVIEVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEECCHHCCCCHHHHCCCCCCCEEEEC
PETYDVRADGELLVCEPAEVLPMAQRYFLF
CCEEEEECCCCEEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]