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The map label for this gene is ytfL [C]

Identifier: 154248060

GI number: 154248060

Start: 4580564

End: 4581922

Strand: Direct

Name: ytfL [C]

Synonym: Xaut_4139

Alternate gene names: 154248060

Gene position: 4580564-4581922 (Clockwise)

Preceding gene: 154248055

Following gene: 154248067

Centisome position: 86.28

GC content: 66.67

Gene sequence:

>1359_bases
ATGTGCTATGAGGAGCGCCGACGGAGAATTTTCTACCCCGCCATGCCTTTGCTCGAAATCCTGATCGTCCTTTTCCTGGT
GTTGCTCAATGCCGTTCTCGCCGCAGCGGAATTGTCCATCGTCTCGTCGCGCCCGGCGCGGCTGAAGACCTTCGCCGACA
AGGGCCGCCGCGGGGCGATTGCCGCGCTGAGGCTGGGGGAAGATCCCGGCCGCTTCCTCTCGACGGTCCAGATCGGCATT
ACCCTTATCGGTATTCTCGCCGGCGCCTTTTCCGGTGCGAGCCTGGGTGAAGCCTTCAGCGGATTCCTGCGCGACTCCGG
CATGCCGGACAGCTTCGCCCAGCCCATCGGCTATACGGTGGTGGTGGCCGCCATTACCTATGTGTCGCTGGTGATCGGCG
AGCTCATCCCGAAGCGGCTGGCCCTGCAGAATCCGGAGCCGCTGGCGTGCATCCTGGCGCCGCTGATGGTCACCCTCTCC
AAGGTGTCGTTGCCGGCGGTGTGGCTGCTCGACAAGTCGACGCGGCTGGTGCTGCGGCTGCTGGGCGAGCGCGGCTCCAG
CTCCAGCGCGGTCACCGACGAGGAGATCCGCGCCATCATCACCGAGGCCGAGACCGCCGGTGTCATCGATCCCGCCGAGC
GGCGCATGATCGCCGGCGTGATGCGTCTCGCCGACCGGCCCGTCACCGCCATCATGACGCCGCGTCCCGACGTGGAATGG
GTGGACATTTCCAAGGATGCGGAAGAGGTACGCCAGGTGCTCCTCGACACCCCCCATTCGCGCCTGCCCGCCTGCGAGGG
TTCGCCGGAGGAAACCATAGGGGTCATCCAGGCCAAGCGCGTGCTGGATGCCTATCTGAAGGGCGAGCGGCCCGATCCCC
GCCAGTTCGTCCAGCAGGTGCCGTTCATCGTGGAGAATGTGGGGGCGCTGGAAGCCATGCGCATCCTGCGTGGCGCCGAG
GTGCCCATGGGCATCGTGGTGGACGAGTATGGCGACATGGCCGGCGTCGTCACTGGCTACGACCTGCTCCTCGCCATCAC
CGGCTCGGTGGATGCGCCCGAGTACAACGAGGCCCGCAACGTGGTGGAGCGGCAGGACGGCAGCTATCTGGTGGCCGGCG
AAACGCCCATCGACGAACTGCGCGACCTGCTCGACGTGGGCTTCCCGGTGGACGACGGCTACCACACGGTGGCGGGCTTC
GCCCTCTCGCACATCAAGGAACTGCCACAGGAAGGCGCCGTGTTCACCGCGCTGGGCTGGCGCTTCGAGATCGTGGACAT
GGACGGCCGGCGCATCGACAAGCTGCTGGTGTCCCGTCCCCACGTTCTCCACCGGCAGAAGGCCGCCGGGGAAGCCTGA

Upstream 100 bases:

>100_bases
GGCCCAAGTTCGGCGCGGAACCTGCTTTAGGGCGCAGGACAACCGTGTTTGCGAAATCGTGGCGTCAAATGTGGCCAGCC
TGTCACACAGGCATGCGCAG

Downstream 100 bases:

>100_bases
CGACCCTCGCCAAAGCGACCCTCGCCCGCCCGGGGCGAGGGTAGCGCAGGCGACCTCAGTCGCGCCGGGCGAGGGAGCGC
AGGAAGCCCTCGTATTCCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MCYEERRRRIFYPAMPLLEILIVLFLVLLNAVLAAAELSIVSSRPARLKTFADKGRRGAIAALRLGEDPGRFLSTVQIGI
TLIGILAGAFSGASLGEAFSGFLRDSGMPDSFAQPIGYTVVVAAITYVSLVIGELIPKRLALQNPEPLACILAPLMVTLS
KVSLPAVWLLDKSTRLVLRLLGERGSSSSAVTDEEIRAIITEAETAGVIDPAERRMIAGVMRLADRPVTAIMTPRPDVEW
VDISKDAEEVRQVLLDTPHSRLPACEGSPEETIGVIQAKRVLDAYLKGERPDPRQFVQQVPFIVENVGALEAMRILRGAE
VPMGIVVDEYGDMAGVVTGYDLLLAITGSVDAPEYNEARNVVERQDGSYLVAGETPIDELRDLLDVGFPVDDGYHTVAGF
ALSHIKELPQEGAVFTALGWRFEIVDMDGRRIDKLLVSRPHVLHRQKAAGEA

Sequences:

>Translated_452_residues
MCYEERRRRIFYPAMPLLEILIVLFLVLLNAVLAAAELSIVSSRPARLKTFADKGRRGAIAALRLGEDPGRFLSTVQIGI
TLIGILAGAFSGASLGEAFSGFLRDSGMPDSFAQPIGYTVVVAAITYVSLVIGELIPKRLALQNPEPLACILAPLMVTLS
KVSLPAVWLLDKSTRLVLRLLGERGSSSSAVTDEEIRAIITEAETAGVIDPAERRMIAGVMRLADRPVTAIMTPRPDVEW
VDISKDAEEVRQVLLDTPHSRLPACEGSPEETIGVIQAKRVLDAYLKGERPDPRQFVQQVPFIVENVGALEAMRILRGAE
VPMGIVVDEYGDMAGVVTGYDLLLAITGSVDAPEYNEARNVVERQDGSYLVAGETPIDELRDLLDVGFPVDDGYHTVAGF
ALSHIKELPQEGAVFTALGWRFEIVDMDGRRIDKLLVSRPHVLHRQKAAGEA
>Mature_452_residues
MCYEERRRRIFYPAMPLLEILIVLFLVLLNAVLAAAELSIVSSRPARLKTFADKGRRGAIAALRLGEDPGRFLSTVQIGI
TLIGILAGAFSGASLGEAFSGFLRDSGMPDSFAQPIGYTVVVAAITYVSLVIGELIPKRLALQNPEPLACILAPLMVTLS
KVSLPAVWLLDKSTRLVLRLLGERGSSSSAVTDEEIRAIITEAETAGVIDPAERRMIAGVMRLADRPVTAIMTPRPDVEW
VDISKDAEEVRQVLLDTPHSRLPACEGSPEETIGVIQAKRVLDAYLKGERPDPRQFVQQVPFIVENVGALEAMRILRGAE
VPMGIVVDEYGDMAGVVTGYDLLLAITGSVDAPEYNEARNVVERQDGSYLVAGETPIDELRDLLDVGFPVDDGYHTVAGF
ALSHIKELPQEGAVFTALGWRFEIVDMDGRRIDKLLVSRPHVLHRQKAAGEA

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=391, Percent_Identity=24.5524296675192, Blast_Score=166, Evalue=3e-41,
Organism=Escherichia coli, GI1790664, Length=427, Percent_Identity=29.03981264637, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI145693175, Length=417, Percent_Identity=26.8585131894484, Blast_Score=138, Evalue=9e-34,
Organism=Escherichia coli, GI87082033, Length=274, Percent_Identity=29.1970802919708, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788119, Length=277, Percent_Identity=31.0469314079422, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786879, Length=253, Percent_Identity=25.296442687747, Blast_Score=78, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49184; Mature: 49184

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCYEERRRRIFYPAMPLLEILIVLFLVLLNAVLAAAELSIVSSRPARLKTFADKGRRGAI
CCCHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCE
AALRLGEDPGRFLSTVQIGITLIGILAGAFSGASLGEAFSGFLRDSGMPDSFAQPIGYTV
EEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHCCCHHHH
VVAAITYVSLVIGELIPKRLALQNPEPLACILAPLMVTLSKVSLPAVWLLDKSTRLVLRL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHH
LGERGSSSSAVTDEEIRAIITEAETAGVIDPAERRMIAGVMRLADRPVTAIMTPRPDVEW
HHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCEE
VDISKDAEEVRQVLLDTPHSRLPACEGSPEETIGVIQAKRVLDAYLKGERPDPRQFVQQV
EECCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHC
PFIVENVGALEAMRILRGAEVPMGIVVDEYGDMAGVVTGYDLLLAITGSVDAPEYNEARN
CHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHEEEEEEECCCCCCCHHHHHH
VVERQDGSYLVAGETPIDELRDLLDVGFPVDDGYHTVAGFALSHIKELPQEGAVFTALGW
HHHHCCCCEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCHHCCCEEEEECC
RFEIVDMDGRRIDKLLVSRPHVLHRQKAAGEA
EEEEEECCCHHHHHHHHCCCHHHHHHHHCCCC
>Mature Secondary Structure
MCYEERRRRIFYPAMPLLEILIVLFLVLLNAVLAAAELSIVSSRPARLKTFADKGRRGAI
CCCHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCE
AALRLGEDPGRFLSTVQIGITLIGILAGAFSGASLGEAFSGFLRDSGMPDSFAQPIGYTV
EEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHCCCHHHH
VVAAITYVSLVIGELIPKRLALQNPEPLACILAPLMVTLSKVSLPAVWLLDKSTRLVLRL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHH
LGERGSSSSAVTDEEIRAIITEAETAGVIDPAERRMIAGVMRLADRPVTAIMTPRPDVEW
HHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCEE
VDISKDAEEVRQVLLDTPHSRLPACEGSPEETIGVIQAKRVLDAYLKGERPDPRQFVQQV
EECCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHC
PFIVENVGALEAMRILRGAEVPMGIVVDEYGDMAGVVTGYDLLLAITGSVDAPEYNEARN
CHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHEEEEEEECCCCCCCHHHHHH
VVERQDGSYLVAGETPIDELRDLLDVGFPVDDGYHTVAGFALSHIKELPQEGAVFTALGW
HHHHCCCCEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCHHCCCEEEEECC
RFEIVDMDGRRIDKLLVSRPHVLHRQKAAGEA
EEEEEECCCHHHHHHHHCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]