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The map label for this gene is hcaT [H]

Identifier: 154248032

GI number: 154248032

Start: 4547416

End: 4548579

Strand: Direct

Name: hcaT [H]

Synonym: Xaut_4111

Alternate gene names: 154248032

Gene position: 4547416-4548579 (Clockwise)

Preceding gene: 154248031

Following gene: 154248034

Centisome position: 85.66

GC content: 71.48

Gene sequence:

>1164_bases
GTGAGGGAGGTCGACGGACGTCCGGCGCTGAAGCTGCGGCTCGGCGGCGCCTATGCGGCGTTCTTCCTCGCCATGGGCAT
CCAGCTGCCCTATCTGCCCCTGTGGTTCCAGCATCGCGGGCTGGGACCCGAGGCCATCGGCGTGGCCCTGGCGGTGCCCA
TGCTGGCACGCCTCGTATCGATGCCCCTGCTGGGCCTGCTCTCCGACTGGCTCGGCCGGCCCAAGGCGTTGCTGGTCGCG
CTGGCGGTGGCGACGGCCTGCGGCATGGTGCTGCTCGCCCTCGCTGCGGATTTTCTCGTTATCCTCGTCGTGCTGGCCTT
CACCGCCCTCGCGTGGATGCCGAGCCTGTCGTTGCTGGATTCCTATGCCTCGCGGCAGGCGCGGGCCGGGCAGGCAGACT
ATGGCAAGGCGCGGCAATGGGGCTCCGCCTCGTTCCTCGTCGCCAATCTTGTGGGCGGCGCGCTCGTCGGCATGCTCGGC
GCCGGCTCCGTGGTGCTGATGATGCTGGCGGGCCAGCTCGCCTATGTGATCGCCACCCTCGCCCTGCCCGAGCTGCCACG
TCCGGAGCCCCGGCCGGCACCGGTGAGCGGGCGGCGGGCCCGGCTCGGGGTACTTGCCGGCATCGTGGCGGCGGCGCTGG
TGCAGGCGAGCCATGCCACGCTCTATGCCTTCGCATCCGTGAGCTGGAGGGCCCAGGGCTATTCGTTCACCGCCATCGGC
GTGCTGTGGGCGGTGGGGGTGGCGGCGGAAATGGCGCTGTTCCGCTTCGGCACCCGCCTCGTGGTCCGCTTCGGACCCCA
TGCGCTCATCGCGGTGGGCGGGATCACGGCAGTGGTGCGCTTCGCCGCCATGGCGAGCGAGCCGCCGCTGGCGGTGCTGG
TGCTGCTGCAACTGCTGCACGCCTTCACCTTCGCCGCCACCTTCCTCGCCATGGTGGAACTGGTGAGCCGCAGCGTCAGC
GAGCATCGTTCCGGCACCGGACAGACCGCCGCCGCCTGGATCGGCAGCATCCTGATGTCATCCGCGAACGTCGCGTCAGG
CCCGCTGTGGGCCGCCTTCGGGCCGCTGGCCTTCCTGGTCTCCAGCGCCATCGGGCTGGCGGGGGCGCTCACCGCGCTCC
TCGCCGCCCGGCTTCAGCCCCACAGCTCCGGCTCGGGCGGATAG

Upstream 100 bases:

>100_bases
TCTCCGGTGGCACGGCGGTTATCGTGCTCTCCGGCGGCAATGTGGAGCCCGAGACCTTCATCCGCTGCCTCGCCGCCTGA
GCCTGGCGGTGGCGAATCAG

Downstream 100 bases:

>100_bases
ACCACGGCGCCCTCGTATCGCAGCCCCGGCGTGCGGTCACGGGCGAGCAGAAGCGGGCCGTCGAGGTCCACCACCTGCGC
CCGCTGCGCCACCAGCAGGG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MREVDGRPALKLRLGGAYAAFFLAMGIQLPYLPLWFQHRGLGPEAIGVALAVPMLARLVSMPLLGLLSDWLGRPKALLVA
LAVATACGMVLLALAADFLVILVVLAFTALAWMPSLSLLDSYASRQARAGQADYGKARQWGSASFLVANLVGGALVGMLG
AGSVVLMMLAGQLAYVIATLALPELPRPEPRPAPVSGRRARLGVLAGIVAAALVQASHATLYAFASVSWRAQGYSFTAIG
VLWAVGVAAEMALFRFGTRLVVRFGPHALIAVGGITAVVRFAAMASEPPLAVLVLLQLLHAFTFAATFLAMVELVSRSVS
EHRSGTGQTAAAWIGSILMSSANVASGPLWAAFGPLAFLVSSAIGLAGALTALLAARLQPHSSGSGG

Sequences:

>Translated_387_residues
MREVDGRPALKLRLGGAYAAFFLAMGIQLPYLPLWFQHRGLGPEAIGVALAVPMLARLVSMPLLGLLSDWLGRPKALLVA
LAVATACGMVLLALAADFLVILVVLAFTALAWMPSLSLLDSYASRQARAGQADYGKARQWGSASFLVANLVGGALVGMLG
AGSVVLMMLAGQLAYVIATLALPELPRPEPRPAPVSGRRARLGVLAGIVAAALVQASHATLYAFASVSWRAQGYSFTAIG
VLWAVGVAAEMALFRFGTRLVVRFGPHALIAVGGITAVVRFAAMASEPPLAVLVLLQLLHAFTFAATFLAMVELVSRSVS
EHRSGTGQTAAAWIGSILMSSANVASGPLWAAFGPLAFLVSSAIGLAGALTALLAARLQPHSSGSGG
>Mature_387_residues
MREVDGRPALKLRLGGAYAAFFLAMGIQLPYLPLWFQHRGLGPEAIGVALAVPMLARLVSMPLLGLLSDWLGRPKALLVA
LAVATACGMVLLALAADFLVILVVLAFTALAWMPSLSLLDSYASRQARAGQADYGKARQWGSASFLVANLVGGALVGMLG
AGSVVLMMLAGQLAYVIATLALPELPRPEPRPAPVSGRRARLGVLAGIVAAALVQASHATLYAFASVSWRAQGYSFTAIG
VLWAVGVAAEMALFRFGTRLVVRFGPHALIAVGGITAVVRFAAMASEPPLAVLVLLQLLHAFTFAATFLAMVELVSRSVS
EHRSGTGQTAAAWIGSILMSSANVASGPLWAAFGPLAFLVSSAIGLAGALTALLAARLQPHSSGSGG

Specific function: Probable permease involved in the uptake of 3- phenylpropionic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacY/rafB permease family. HcaT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788886, Length=320, Percent_Identity=30.3125, Blast_Score=121, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022814
- InterPro:   IPR016196
- InterPro:   IPR005276 [H]

Pfam domain/function: PF01306 LacY_symp [H]

EC number: NA

Molecular weight: Translated: 39985; Mature: 39985

Theoretical pI: Translated: 11.27; Mature: 11.27

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREVDGRPALKLRLGGAYAAFFLAMGIQLPYLPLWFQHRGLGPEAIGVALAVPMLARLVS
CCCCCCCCCEEEEECHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHH
MPLLGLLSDWLGRPKALLVALAVATACGMVLLALAADFLVILVVLAFTALAWMPSLSLLD
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
SYASRQARAGQADYGKARQWGSASFLVANLVGGALVGMLGAGSVVLMMLAGQLAYVIATL
HHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALPELPRPEPRPAPVSGRRARLGVLAGIVAAALVQASHATLYAFASVSWRAQGYSFTAIG
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHH
VLWAVGVAAEMALFRFGTRLVVRFGPHALIAVGGITAVVRFAAMASEPPLAVLVLLQLLH
HHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
AFTFAATFLAMVELVSRSVSEHRSGTGQTAAAWIGSILMSSANVASGPLWAAFGPLAFLV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
SSAIGLAGALTALLAARLQPHSSGSGG
HHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MREVDGRPALKLRLGGAYAAFFLAMGIQLPYLPLWFQHRGLGPEAIGVALAVPMLARLVS
CCCCCCCCCEEEEECHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHH
MPLLGLLSDWLGRPKALLVALAVATACGMVLLALAADFLVILVVLAFTALAWMPSLSLLD
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
SYASRQARAGQADYGKARQWGSASFLVANLVGGALVGMLGAGSVVLMMLAGQLAYVIATL
HHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALPELPRPEPRPAPVSGRRARLGVLAGIVAAALVQASHATLYAFASVSWRAQGYSFTAIG
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHH
VLWAVGVAAEMALFRFGTRLVVRFGPHALIAVGGITAVVRFAAMASEPPLAVLVLLQLLH
HHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
AFTFAATFLAMVELVSRSVSEHRSGTGQTAAAWIGSILMSSANVASGPLWAAFGPLAFLV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
SSAIGLAGALTALLAARLQPHSSGSGG
HHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9603882; 9205837; 9278503 [H]