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The map label for this gene is gatB

Identifier: 154247851

GI number: 154247851

Start: 4345546

End: 4347036

Strand: Direct

Name: gatB

Synonym: Xaut_3928

Alternate gene names: 154247851

Gene position: 4345546-4347036 (Clockwise)

Preceding gene: 154247849

Following gene: 154247854

Centisome position: 81.85

GC content: 65.93

Gene sequence:

>1491_bases
ATGACCTTACATGTTCGCCCTACCGATACGAAGAAGCTCATTTCCGGTGCCACCGGCGATTGGGAAGTGGTGATCGGCCT
GGAGGTGCATGCCCAGGTGGCCTCCAACGCCAAGCTGTTCTCCGGCGCCTCCACCGCTTTCGGCGGCCCGCCCAATGACC
ATGTGTCGCTGGTGGATGCGGCCATGCCCGGCATGCTGCCCGTCATCAACCAGGAATGCGTGGCCCAGGCAGTGCGCACC
GGCCTCGGCCTGAAGGCGCAGATCCACCTGACTTCGGTGTTCGACCGGAAGAACTACTTCTACCCGGACCTGCCGCAGGG
CTACCAAATCAGCCAGTACAAGCAGCCGGTGGTGGGCGAGGGCGAGGTCATCGTGGACCTGCCCGACGGGGAGAGCATCC
CCGTCGGCATCGAGCGCCTGCACCTGGAGCAGGACGCCGGCAAGTCCATCCACGACCTGTCGCCCACCCAGTCCTTCGTG
GACCTCAACCGCTCCGGCGTGGCGCTGATGGAGATCGTCTCCCGCCCCGACCTGCGCTCGGCGGAGGAGGCGAAGGCCTA
TGTGACGAAGCTGCGCACCATCCTGAGGTATCTTGGCACCTGCGACGGCGACATGGAGAAGGGCAACCTGCGGGCGGACG
TGAACGTCTCCGTGCGCCGCCCCGGCGAACCCTTCGGCACCCGCTGCGAGATCAAAAACGTCAATTCCATCCGCTTCATC
GGCCAGGCCATCGAGACCGAGGCGCGGCGGCAGATCGAGATCCTGGAGGATGGCGGCTCCATCTCCCAGGAGACGCGCCT
GTTCGACCCCACCAGGGGCGAAACGCGCTCCATGCGCTCGAAGGAAGAGGCGCACGACTACCGTTACTTCCCCGATCCGG
ACCTGCTGCCGCTGGTGCTGAAGCCCGAGTGGGTGGAGGAGCTGAAGTCCGGCCTGCCCGAGCTGCCGGACGAGAAGAAG
GCCCGCTTCATCGCCGATTACGGCTTGAGCCCCTATGACGCCGGCGTGCTGGTGGCCGAGCGCGAAACGGCGGCCTATTT
CGAGCAGGTGGCGGACGGCGGCGGCGTCAAGCGCGACGGCAAGGCGGCCGCGAACTTCGTCATCAACGAACTGTTCGGCC
GCCTGAACAAGGAGGGCAAGGATGTCACCTCCTCGCCCGTGACGCCGCACCAGATCGGCGCCATCCTCGACCTGATCGCG
GAGGGCACCATCTCCTCCAAGATCGCCAAGGACCTGTTCGAGATCATCTTCACCGAGGGCGGCGACCCGCGCGTGGTGGT
GGAAGCCCGCGGCCTGAAGCAGGTGACCGACCTCGGCGCCATCGAGAAGGTGGTGGACGAGATCATCGCCAAGAACCCGG
ACAAGGTGGCGCAGGTGCTGGCCAAGCCCACCATGCTGGGCTGGTTCGTGGGCCAGGCCATGAAGGCCTCCGGCGGCAAG
GCCAACCCGCAGGCCCTCAACGACATCCTGAAGGCCAAGCTCGGGATCTGA

Upstream 100 bases:

>100_bases
ACGGCCCGGCGTTGCGCGCACGCCCCGTTGGGGAGTAGTGAGTTTAAGAGAAACGCTGATCGCCCGCGCGCCGACGCGGC
GGCTAGTTCCGGGACCTTTC

Downstream 100 bases:

>100_bases
GCGCTCTTCGGCACAATCCCGAAAACACCAATGCCCGGCTCGCGCCGGGCATTGTCGTTCTGGCGGGGCCATAATCGAAA
AATGTGTGACCGGATCCCGA

Product: glutamyl-tRNA(Gln) amidotransferase subunit B

Products: NA

Alternate protein names: Asp/Glu-ADT subunit B

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MTLHVRPTDTKKLISGATGDWEVVIGLEVHAQVASNAKLFSGASTAFGGPPNDHVSLVDAAMPGMLPVINQECVAQAVRT
GLGLKAQIHLTSVFDRKNYFYPDLPQGYQISQYKQPVVGEGEVIVDLPDGESIPVGIERLHLEQDAGKSIHDLSPTQSFV
DLNRSGVALMEIVSRPDLRSAEEAKAYVTKLRTILRYLGTCDGDMEKGNLRADVNVSVRRPGEPFGTRCEIKNVNSIRFI
GQAIETEARRQIEILEDGGSISQETRLFDPTRGETRSMRSKEEAHDYRYFPDPDLLPLVLKPEWVEELKSGLPELPDEKK
ARFIADYGLSPYDAGVLVAERETAAYFEQVADGGGVKRDGKAAANFVINELFGRLNKEGKDVTSSPVTPHQIGAILDLIA
EGTISSKIAKDLFEIIFTEGGDPRVVVEARGLKQVTDLGAIEKVVDEIIAKNPDKVAQVLAKPTMLGWFVGQAMKASGGK
ANPQALNDILKAKLGI

Sequences:

>Translated_496_residues
MTLHVRPTDTKKLISGATGDWEVVIGLEVHAQVASNAKLFSGASTAFGGPPNDHVSLVDAAMPGMLPVINQECVAQAVRT
GLGLKAQIHLTSVFDRKNYFYPDLPQGYQISQYKQPVVGEGEVIVDLPDGESIPVGIERLHLEQDAGKSIHDLSPTQSFV
DLNRSGVALMEIVSRPDLRSAEEAKAYVTKLRTILRYLGTCDGDMEKGNLRADVNVSVRRPGEPFGTRCEIKNVNSIRFI
GQAIETEARRQIEILEDGGSISQETRLFDPTRGETRSMRSKEEAHDYRYFPDPDLLPLVLKPEWVEELKSGLPELPDEKK
ARFIADYGLSPYDAGVLVAERETAAYFEQVADGGGVKRDGKAAANFVINELFGRLNKEGKDVTSSPVTPHQIGAILDLIA
EGTISSKIAKDLFEIIFTEGGDPRVVVEARGLKQVTDLGAIEKVVDEIIAKNPDKVAQVLAKPTMLGWFVGQAMKASGGK
ANPQALNDILKAKLGI
>Mature_495_residues
TLHVRPTDTKKLISGATGDWEVVIGLEVHAQVASNAKLFSGASTAFGGPPNDHVSLVDAAMPGMLPVINQECVAQAVRTG
LGLKAQIHLTSVFDRKNYFYPDLPQGYQISQYKQPVVGEGEVIVDLPDGESIPVGIERLHLEQDAGKSIHDLSPTQSFVD
LNRSGVALMEIVSRPDLRSAEEAKAYVTKLRTILRYLGTCDGDMEKGNLRADVNVSVRRPGEPFGTRCEIKNVNSIRFIG
QAIETEARRQIEILEDGGSISQETRLFDPTRGETRSMRSKEEAHDYRYFPDPDLLPLVLKPEWVEELKSGLPELPDEKKA
RFIADYGLSPYDAGVLVAERETAAYFEQVADGGGVKRDGKAAANFVINELFGRLNKEGKDVTSSPVTPHQIGAILDLIAE
GTISSKIAKDLFEIIFTEGGDPRVVVEARGLKQVTDLGAIEKVVDEIIAKNPDKVAQVLAKPTMLGWFVGQAMKASGGKA
NPQALNDILKAKLGI

Specific function: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction take

COG id: COG0064

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gatB/gatE family. GatB subfamily

Homologues:

Organism=Homo sapiens, GI4758894, Length=512, Percent_Identity=40.234375, Blast_Score=372, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI115534094, Length=309, Percent_Identity=43.3656957928803, Blast_Score=229, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6319391, Length=527, Percent_Identity=31.4990512333966, Blast_Score=232, Evalue=1e-61,
Organism=Drosophila melanogaster, GI45550808, Length=490, Percent_Identity=37.5510204081633, Blast_Score=315, Evalue=3e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GATB_XANP2 (A7IMA9)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001418809.1
- ProteinModelPortal:   A7IMA9
- SMR:   A7IMA9
- STRING:   A7IMA9
- GeneID:   5422612
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_3928
- eggNOG:   COG0064
- HOGENOM:   HBG395951
- OMA:   LRYLGTC
- ProtClustDB:   CLSK980142
- BioCyc:   XAUT78245:XAUT_3928-MONOMER
- GO:   GO:0006412
- HAMAP:   MF_00121
- InterPro:   IPR017959
- InterPro:   IPR018027
- InterPro:   IPR003789
- InterPro:   IPR004413
- InterPro:   IPR006075
- InterPro:   IPR017958
- PANTHER:   PTHR11659
- SMART:   SM00845
- TIGRFAMs:   TIGR00133

Pfam domain/function: PF02934 GatB_N; PF02637 GatB_Yqey; SSF89095 GatB_Yqey

EC number: 6.3.5.-

Molecular weight: Translated: 54007; Mature: 53876

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS01234 GATB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLHVRPTDTKKLISGATGDWEVVIGLEVHAQVASNAKLFSGASTAFGGPPNDHVSLVDA
CEEECCCCCHHHHHCCCCCCEEEEEEEEEEEHHHCCCEEECCCCCCCCCCCCCCHHHHHH
AMPGMLPVINQECVAQAVRTGLGLKAQIHLTSVFDRKNYFYPDLPQGYQISQYKQPVVGE
HCCCCCHHHCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCC
GEVIVDLPDGESIPVGIERLHLEQDAGKSIHDLSPTQSFVDLNRSGVALMEIVSRPDLRS
CCEEEECCCCCCCCCCHHHEEEHHHCCCCCCCCCCCHHHHHCCCCCHHHHHHHCCCCCCC
AEEAKAYVTKLRTILRYLGTCDGDMEKGNLRADVNVSVRRPGEPFGTRCEIKNVNSIRFI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEECCCCHHHHH
GQAIETEARRQIEILEDGGSISQETRLFDPTRGETRSMRSKEEAHDYRYFPDPDLLPLVL
HHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEE
KPEWVEELKSGLPELPDEKKARFIADYGLSPYDAGVLVAERETAAYFEQVADGGGVKRDG
CCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCCCC
KAAANFVINELFGRLNKEGKDVTSSPVTPHQIGAILDLIAEGTISSKIAKDLFEIIFTEG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
GDPRVVVEARGLKQVTDLGAIEKVVDEIIAKNPDKVAQVLAKPTMLGWFVGQAMKASGGK
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHCCCCC
ANPQALNDILKAKLGI
CCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLHVRPTDTKKLISGATGDWEVVIGLEVHAQVASNAKLFSGASTAFGGPPNDHVSLVDA
EEECCCCCHHHHHCCCCCCEEEEEEEEEEEHHHCCCEEECCCCCCCCCCCCCCHHHHHH
AMPGMLPVINQECVAQAVRTGLGLKAQIHLTSVFDRKNYFYPDLPQGYQISQYKQPVVGE
HCCCCCHHHCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCC
GEVIVDLPDGESIPVGIERLHLEQDAGKSIHDLSPTQSFVDLNRSGVALMEIVSRPDLRS
CCEEEECCCCCCCCCCHHHEEEHHHCCCCCCCCCCCHHHHHCCCCCHHHHHHHCCCCCCC
AEEAKAYVTKLRTILRYLGTCDGDMEKGNLRADVNVSVRRPGEPFGTRCEIKNVNSIRFI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEECCCCHHHHH
GQAIETEARRQIEILEDGGSISQETRLFDPTRGETRSMRSKEEAHDYRYFPDPDLLPLVL
HHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEE
KPEWVEELKSGLPELPDEKKARFIADYGLSPYDAGVLVAERETAAYFEQVADGGGVKRDG
CCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCCCC
KAAANFVINELFGRLNKEGKDVTSSPVTPHQIGAILDLIAEGTISSKIAKDLFEIIFTEG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
GDPRVVVEARGLKQVTDLGAIEKVVDEIIAKNPDKVAQVLAKPTMLGWFVGQAMKASGGK
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHCCCCC
ANPQALNDILKAKLGI
CCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA