Click here to switch to the map view.

The map label for this gene is hupA [C]

Identifier: 154247521

GI number: 154247521

Start: 4020750

End: 4021028

Strand: Direct

Name: hupA [C]

Synonym: Xaut_3594

Alternate gene names: 154247521

Gene position: 4020750-4021028 (Clockwise)

Preceding gene: 154247520

Following gene: 154247537

Centisome position: 75.74

GC content: 64.16

Gene sequence:

>279_bases
ATGACCACCAAGAACGAACTGATCGCCGCGGTGGCCGAAGAGGCGAAGCTGACGAAGACGGCCGCGGCTGCGGCTGTGGA
CGCCACCTTCGACATCATCGCCAAGGCGCTGCAGGAAGGCGAGGAAGTCAAGCTGATCGGTTTCGGCAGCTTTTCCGTGG
TGACGCGCGCCGCGCGCGAAGGCCGCAATCCCCGCACCGGCAAGCCTGTCAAGATCAAGGCTTCCAAGGCTCCGAAGTTC
ACCCCCGGCAAGGGCCTGAAGGAAGCCGTCAACGGCTGA

Upstream 100 bases:

>100_bases
CGATCGCGCTTGCAAAAGCCTTATTTTCCGTGATGCTCGCGCCGTTCGTGAGGGCTTGAGCCTGCACGATTCGCGTTCTG
ACAACGGAAGGAAAGGTCAG

Downstream 100 bases:

>100_bases
TCGGCCCCCGGGTCCCTGACGCGGGGACCCCTCCAAAGGCTTCCCGGACGCTCCCGGCCCGCCCATTTGGCGGGCGGAGC
GTCCCCGAGCCGCACGGCGG

Product: histone family protein DNA-binding protein

Products: NA

Alternate protein names: HU-like protein; Px [H]

Number of amino acids: Translated: 92; Mature: 91

Protein sequence:

>92_residues
MTTKNELIAAVAEEAKLTKTAAAAAVDATFDIIAKALQEGEEVKLIGFGSFSVVTRAAREGRNPRTGKPVKIKASKAPKF
TPGKGLKEAVNG

Sequences:

>Translated_92_residues
MTTKNELIAAVAEEAKLTKTAAAAAVDATFDIIAKALQEGEEVKLIGFGSFSVVTRAAREGRNPRTGKPVKIKASKAPKF
TPGKGLKEAVNG
>Mature_91_residues
TTKNELIAAVAEEAKLTKTAAAAAVDATFDIIAKALQEGEEVKLIGFGSFSVVTRAAREGRNPRTGKPVKIKASKAPKFT
PGKGLKEAVNG

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Binds to nod promoters and induces DNA binding [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1790433, Length=87, Percent_Identity=51.7241379310345, Blast_Score=92, Evalue=8e-21,
Organism=Escherichia coli, GI1786644, Length=89, Percent_Identity=49.438202247191, Blast_Score=89, Evalue=6e-20,
Organism=Escherichia coli, GI1787141, Length=90, Percent_Identity=38.8888888888889, Blast_Score=70, Evalue=3e-14,
Organism=Escherichia coli, GI1788005, Length=88, Percent_Identity=39.7727272727273, Blast_Score=67, Evalue=2e-13,

Paralogues:

None

Copy number: 1380 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9583; Mature: 9452

Theoretical pI: Translated: 10.65; Mature: 10.65

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKNELIAAVAEEAKLTKTAAAAAVDATFDIIAKALQEGEEVKLIGFGSFSVVTRAARE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHC
GRNPRTGKPVKIKASKAPKFTPGKGLKEAVNG
CCCCCCCCCEEEECCCCCCCCCCCCHHHHHCC
>Mature Secondary Structure 
TTKNELIAAVAEEAKLTKTAAAAAVDATFDIIAKALQEGEEVKLIGFGSFSVVTRAARE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHC
GRNPRTGKPVKIKASKAPKFTPGKGLKEAVNG
CCCCCCCCCEEEECCCCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 4038648; 9685414 [H]