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The map label for this gene is aatA [H]

Identifier: 154246676

GI number: 154246676

Start: 3030870

End: 3032072

Strand: Reverse

Name: aatA [H]

Synonym: Xaut_2737

Alternate gene names: 154246676

Gene position: 3032072-3030870 (Counterclockwise)

Preceding gene: 154246681

Following gene: 154246675

Centisome position: 57.11

GC content: 65.25

Gene sequence:

>1203_bases
ATGAGCCTCATCTCGTCCGCCCTGAAGCGCATCAAGCCCTCCCAGACCATCGCCATCTCCAACAAGGCGCGGGAGCTCAA
GGCGGCCGGGCGGGACATCGTCGCGCTCTCCGCCGGCGAGCCGGACTTCGACACCCCCGAGAACATCAAGGAAGCGGCCA
TCGCCGCCATCCGCCGGGGCGAGACCAAGTACACGGCCGTGGACGGCATCCCTGAGCTGAAGGCCGCCATCTGCCGCAAG
TTCAAGCGCGAGAACGACCTCGACTACAAGCCTTCGCAGGTCACGGTCGGCACAGGCGGCAAGCAGGTGCTGTTCAACGC
TTTGGTCGCGACGGTGGATGCCGGCGACGAAGTGCTGATCCCCGCCCCGTACTGGGTGAGCTATCCGGACATCGTGGAAT
TCTGCGGCGGCAAGCCGGTGCCGGTGATGACCACCATCGAGGACAACTTCAAGCTGCGTCCCGACGTGCTGGAAGCCGCC
ATCACCCCCAAGACCAAGTGGCTCATCTTCAATTCGCCGTCCAACCCTTCGGGCGCGGCCTATTCCTTCGACGAGCTGAA
GGCGCTCACCGACGTGCTGGTGAAGTATCCGCAGGTGTGGATCCTCACCGACGACATGTACGAGCACCTCGTCTATGACG
ACTTCAAGTTCGTCACCCCGGCGCAGGTGGAGCCGAAGCTCTATAACCGCACGCTGACCATGAACGGCGTGTCGAAGGCC
TATTGCATGACCGGCTGGCGCATCGGCTACGCCGCCGGCCCCGAGGCCCTCATCAAGGCCATGGGCACGCTGCAGTCCCA
GTCCACCTCCAACCCCTCCTCCATCGCCCAGTGGGCGGCGCTTGAGGCGCTGGACGGACCGCAGGACTTCATCGCCGCCA
ACAACAAGGTGTTCAAGGAACGCCGCGACCTGGTGGTGTCCATGCTGAACCAGGCGAAGGGCCTGCACTGCCCCAAGCCC
GAGGGCGCGTTCTACGTCTTCCCGTCCTGCGCCGGCACCATCGGCAAGACCACGCCCGGCGGTGTCACCATCGCCAGCGA
CGAGGACTTCGCCACCCAGCTGCTGGAGGCGGAAGGCGTTGCCGTGGTGCATGGCTCGGCCTTCGGCCTGGGCCCGGCAT
TCCGGATTTCCTATGCCACCGCCACGTCGGACCTTGAGGAAGCCTGCCGGCGCATCCAGCGCTTCTGTGGCTCCCTGAGC
TGA

Upstream 100 bases:

>100_bases
TCCGCGCCGCGTCGGCAGGAGCCGGCTGCGATCCTGCCAAATGCCCAGCCCGCGCCGCCTTTTGCCTCGTGCGGCCGGGC
GCGTCCGGAGCCTAAAGGCC

Downstream 100 bases:

>100_bases
TCCGGGCACAGGGCCCGGAAAAAAGGAACACATAGCCCTTTGAAGCGTTGGCGCAGCAGTGAAGTCTGGGCTAAGGCTTC
GCTGTCGTCGGGTGCAGGGA

Product: class I and II aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSLISSALKRIKPSQTIAISNKARELKAAGRDIVALSAGEPDFDTPENIKEAAIAAIRRGETKYTAVDGIPELKAAICRK
FKRENDLDYKPSQVTVGTGGKQVLFNALVATVDAGDEVLIPAPYWVSYPDIVEFCGGKPVPVMTTIEDNFKLRPDVLEAA
ITPKTKWLIFNSPSNPSGAAYSFDELKALTDVLVKYPQVWILTDDMYEHLVYDDFKFVTPAQVEPKLYNRTLTMNGVSKA
YCMTGWRIGYAAGPEALIKAMGTLQSQSTSNPSSIAQWAALEALDGPQDFIAANNKVFKERRDLVVSMLNQAKGLHCPKP
EGAFYVFPSCAGTIGKTTPGGVTIASDEDFATQLLEAEGVAVVHGSAFGLGPAFRISYATATSDLEEACRRIQRFCGSLS

Sequences:

>Translated_400_residues
MSLISSALKRIKPSQTIAISNKARELKAAGRDIVALSAGEPDFDTPENIKEAAIAAIRRGETKYTAVDGIPELKAAICRK
FKRENDLDYKPSQVTVGTGGKQVLFNALVATVDAGDEVLIPAPYWVSYPDIVEFCGGKPVPVMTTIEDNFKLRPDVLEAA
ITPKTKWLIFNSPSNPSGAAYSFDELKALTDVLVKYPQVWILTDDMYEHLVYDDFKFVTPAQVEPKLYNRTLTMNGVSKA
YCMTGWRIGYAAGPEALIKAMGTLQSQSTSNPSSIAQWAALEALDGPQDFIAANNKVFKERRDLVVSMLNQAKGLHCPKP
EGAFYVFPSCAGTIGKTTPGGVTIASDEDFATQLLEAEGVAVVHGSAFGLGPAFRISYATATSDLEEACRRIQRFCGSLS
>Mature_399_residues
SLISSALKRIKPSQTIAISNKARELKAAGRDIVALSAGEPDFDTPENIKEAAIAAIRRGETKYTAVDGIPELKAAICRKF
KRENDLDYKPSQVTVGTGGKQVLFNALVATVDAGDEVLIPAPYWVSYPDIVEFCGGKPVPVMTTIEDNFKLRPDVLEAAI
TPKTKWLIFNSPSNPSGAAYSFDELKALTDVLVKYPQVWILTDDMYEHLVYDDFKFVTPAQVEPKLYNRTLTMNGVSKAY
CMTGWRIGYAAGPEALIKAMGTLQSQSTSNPSSIAQWAALEALDGPQDFIAANNKVFKERRDLVVSMLNQAKGLHCPKPE
GAFYVFPSCAGTIGKTTPGGVTIASDEDFATQLLEAEGVAVVHGSAFGLGPAFRISYATATSDLEEACRRIQRFCGSLS

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=320, Percent_Identity=32.1875, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI56713256, Length=320, Percent_Identity=32.1875, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI95147551, Length=364, Percent_Identity=28.8461538461538, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI169881279, Length=364, Percent_Identity=28.8461538461538, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI169881281, Length=270, Percent_Identity=26.6666666666667, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI4507369, Length=312, Percent_Identity=25.9615384615385, Blast_Score=90, Evalue=4e-18,
Organism=Escherichia coli, GI1788627, Length=392, Percent_Identity=27.0408163265306, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1788722, Length=362, Percent_Identity=30.1104972375691, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1786816, Length=375, Percent_Identity=25.6, Blast_Score=137, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI71994472, Length=367, Percent_Identity=26.9754768392371, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71994476, Length=367, Percent_Identity=26.9754768392371, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17567663, Length=382, Percent_Identity=25.6544502617801, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17567369, Length=335, Percent_Identity=25.3731343283582, Blast_Score=111, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6322401, Length=312, Percent_Identity=28.525641025641, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320317, Length=370, Percent_Identity=24.3243243243243, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28573069, Length=395, Percent_Identity=24.5569620253165, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24646114, Length=395, Percent_Identity=24.5569620253165, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI28573067, Length=395, Percent_Identity=24.5569620253165, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI28573065, Length=395, Percent_Identity=24.5569620253165, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI18859735, Length=384, Percent_Identity=23.6979166666667, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24641770, Length=395, Percent_Identity=24.5569620253165, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24641760, Length=395, Percent_Identity=24.5569620253165, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24641768, Length=395, Percent_Identity=24.5569620253165, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24641766, Length=395, Percent_Identity=24.5569620253165, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24641764, Length=395, Percent_Identity=24.5569620253165, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI45551451, Length=395, Percent_Identity=24.5569620253165, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43352; Mature: 43221

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLISSALKRIKPSQTIAISNKARELKAAGRDIVALSAGEPDFDTPENIKEAAIAAIRRG
CHHHHHHHHHCCCCCEEEECCHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCC
ETKYTAVDGIPELKAAICRKFKRENDLDYKPSQVTVGTGGKQVLFNALVATVDAGDEVLI
CCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEE
PAPYWVSYPDIVEFCGGKPVPVMTTIEDNFKLRPDVLEAAITPKTKWLIFNSPSNPSGAA
CCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCC
YSFDELKALTDVLVKYPQVWILTDDMYEHLVYDDFKFVTPAQVEPKLYNRTLTMNGVSKA
CCHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHCCCCCCCCCCCCHHHHCEEEEECCCCHH
YCMTGWRIGYAAGPEALIKAMGTLQSQSTSNPSSIAQWAALEALDGPQDFIAANNKVFKE
HHHCCCEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCHHHHHH
RRDLVVSMLNQAKGLHCPKPEGAFYVFPSCAGTIGKTTPGGVTIASDEDFATQLLEAEGV
HHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHCCE
AVVHGSAFGLGPAFRISYATATSDLEEACRRIQRFCGSLS
EEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLISSALKRIKPSQTIAISNKARELKAAGRDIVALSAGEPDFDTPENIKEAAIAAIRRG
HHHHHHHHHCCCCCEEEECCHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCC
ETKYTAVDGIPELKAAICRKFKRENDLDYKPSQVTVGTGGKQVLFNALVATVDAGDEVLI
CCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEE
PAPYWVSYPDIVEFCGGKPVPVMTTIEDNFKLRPDVLEAAITPKTKWLIFNSPSNPSGAA
CCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCC
YSFDELKALTDVLVKYPQVWILTDDMYEHLVYDDFKFVTPAQVEPKLYNRTLTMNGVSKA
CCHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHCCCCCCCCCCCCHHHHCEEEEECCCCHH
YCMTGWRIGYAAGPEALIKAMGTLQSQSTSNPSSIAQWAALEALDGPQDFIAANNKVFKE
HHHCCCEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCHHHHHH
RRDLVVSMLNQAKGLHCPKPEGAFYVFPSCAGTIGKTTPGGVTIASDEDFATQLLEAEGV
HHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHCCE
AVVHGSAFGLGPAFRISYATATSDLEEACRRIQRFCGSLS
EEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]