Click here to switch to the map view.

The map label for this gene is aroE [H]

Identifier: 154246643

GI number: 154246643

Start: 2993005

End: 2993811

Strand: Reverse

Name: aroE [H]

Synonym: Xaut_2703

Alternate gene names: 154246643

Gene position: 2993811-2993005 (Counterclockwise)

Preceding gene: 154246644

Following gene: 154246642

Centisome position: 56.39

GC content: 68.28

Gene sequence:

>807_bases
ATGAACATCGACCTGTCCGGCGCCACCCGCCTCTACATCATCGTCGGCGATCCGATCGCCCAGGTGAAATCCCCCGCCGG
CATGACGGCAGCTTTTCTCTCCCGCAATCATGACGGCATCCTTGTGCCGGTGCAGGTGGGAACCGGGGATCTCGGCGACC
TGCTTGCCGTCTCGGGCAAGCTGAAAAATCTCGGCGGCGTCGTCGTCACCGTGCCCCACAAGTTCGGCTGCTTCTCCCAC
TGCGCCGAAGCCTCCGACCGCGCCGCCTTCATCGGCTCGGTGAACATCATGCGCCAGCGACCCGAAGGCGGTTGGTATGG
CGACATCGTGGACGGCCTCGGCTTCGTCAGCGCCGCGGTCAATGCGGGCTTCGATCCTGACGGCAAGCGGGCGCTGCTGG
TTGGGGCGGGCGGCGCGGGTTCCGCCATCGCTCTCGCCCTGATCGATGCGGGCGTTGCCGAGCTCGCCATCCATGACGCC
GATGTGGCGCGGCGCGATGCCCTCGTCGCCCGCCTCAACACCCTCGGCAAGGGCCGGGCGGTGGCGGGTTCCACCGATCC
CGCTGGCTTCGACCTCGTCGCCAACGCCACGCCCATGGGCATGAAGGAGGGCGATCCGCTGCCCGTGGATGTGACGAGGC
TCGTGCCCGCGACCCATGTGGGCTGCGTCATCACCCAGCCGGCGGTGTCGCCGCTGATCGCCGCCGCCCGCGCCGCCGGC
TGCCCCACCTCCACCGGCACCGAGATGTACTTCGCCCTGCAGGAGAAGATGGTGGACTTCCTGCTGCACACCGACTCCAA
CGCTTGA

Upstream 100 bases:

>100_bases
AAGCCGATCACGCCCTGCAGGCCCGCCTCCTGGGCGTGGTGCAGGGCGAAGACCTCATCGCCGCGGCCAGCTGACGCGCG
CCATCTCCACGGAGCCCCCC

Downstream 100 bases:

>100_bases
GCCGGCGCCATGATCACCACCCTGGATGCCCTCCCCCCAGACGATGTCCATGACCTCGTCGTCGTCGGCTCCGGAGCCGG
CGGAATGGCGACGGCGCTGT

Product: shikimate dehydrogenase substrate binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MNIDLSGATRLYIIVGDPIAQVKSPAGMTAAFLSRNHDGILVPVQVGTGDLGDLLAVSGKLKNLGGVVVTVPHKFGCFSH
CAEASDRAAFIGSVNIMRQRPEGGWYGDIVDGLGFVSAAVNAGFDPDGKRALLVGAGGAGSAIALALIDAGVAELAIHDA
DVARRDALVARLNTLGKGRAVAGSTDPAGFDLVANATPMGMKEGDPLPVDVTRLVPATHVGCVITQPAVSPLIAAARAAG
CPTSTGTEMYFALQEKMVDFLLHTDSNA

Sequences:

>Translated_268_residues
MNIDLSGATRLYIIVGDPIAQVKSPAGMTAAFLSRNHDGILVPVQVGTGDLGDLLAVSGKLKNLGGVVVTVPHKFGCFSH
CAEASDRAAFIGSVNIMRQRPEGGWYGDIVDGLGFVSAAVNAGFDPDGKRALLVGAGGAGSAIALALIDAGVAELAIHDA
DVARRDALVARLNTLGKGRAVAGSTDPAGFDLVANATPMGMKEGDPLPVDVTRLVPATHVGCVITQPAVSPLIAAARAAG
CPTSTGTEMYFALQEKMVDFLLHTDSNA
>Mature_268_residues
MNIDLSGATRLYIIVGDPIAQVKSPAGMTAAFLSRNHDGILVPVQVGTGDLGDLLAVSGKLKNLGGVVVTVPHKFGCFSH
CAEASDRAAFIGSVNIMRQRPEGGWYGDIVDGLGFVSAAVNAGFDPDGKRALLVGAGGAGSAIALALIDAGVAELAIHDA
DVARRDALVARLNTLGKGRAVAGSTDPAGFDLVANATPMGMKEGDPLPVDVTRLVPATHVGCVITQPAVSPLIAAARAAG
CPTSTGTEMYFALQEKMVDFLLHTDSNA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=234, Percent_Identity=29.9145299145299, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787983, Length=214, Percent_Identity=29.4392523364486, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 27312; Mature: 27312

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIDLSGATRLYIIVGDPIAQVKSPAGMTAAFLSRNHDGILVPVQVGTGDLGDLLAVSGK
CCCCCCCCEEEEEEECCCHHHHCCCCCCCHHHHCCCCCCEEEEEEECCCCHHHHHHHCCC
LKNLGGVVVTVPHKFGCFSHCAEASDRAAFIGSVNIMRQRPEGGWYGDIVDGLGFVSAAV
HHCCCCEEEECCCCCCHHHHHHCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHH
NAGFDPDGKRALLVGAGGAGSAIALALIDAGVAELAIHDADVARRDALVARLNTLGKGRA
HCCCCCCCCEEEEEECCCCCHHHEEHHHHCCHHHEEECCHHHHHHHHHHHHHHHCCCCCE
VAGSTDPAGFDLVANATPMGMKEGDPLPVDVTRLVPATHVGCVITQPAVSPLIAAARAAG
ECCCCCCCCEEEEECCCCCCCCCCCCCCEEHHHHCCCHHCCEEEECHHHHHHHHHHHHCC
CPTSTGTEMYFALQEKMVDFLLHTDSNA
CCCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNIDLSGATRLYIIVGDPIAQVKSPAGMTAAFLSRNHDGILVPVQVGTGDLGDLLAVSGK
CCCCCCCCEEEEEEECCCHHHHCCCCCCCHHHHCCCCCCEEEEEEECCCCHHHHHHHCCC
LKNLGGVVVTVPHKFGCFSHCAEASDRAAFIGSVNIMRQRPEGGWYGDIVDGLGFVSAAV
HHCCCCEEEECCCCCCHHHHHHCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHH
NAGFDPDGKRALLVGAGGAGSAIALALIDAGVAELAIHDADVARRDALVARLNTLGKGRA
HCCCCCCCCEEEEEECCCCCHHHEEHHHHCCHHHEEECCHHHHHHHHHHHHHHHCCCCCE
VAGSTDPAGFDLVANATPMGMKEGDPLPVDVTRLVPATHVGCVITQPAVSPLIAAARAAG
ECCCCCCCCEEEEECCCCCCCCCCCCCCEEHHHHCCCHHCCEEEECHHHHHHHHHHHHCC
CPTSTGTEMYFALQEKMVDFLLHTDSNA
CCCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA