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The map label for this gene is ksdD [H]

Identifier: 154246641

GI number: 154246641

Start: 2989478

End: 2991277

Strand: Reverse

Name: ksdD [H]

Synonym: Xaut_2701

Alternate gene names: 154246641

Gene position: 2991277-2989478 (Counterclockwise)

Preceding gene: 154246642

Following gene: 154246640

Centisome position: 56.34

GC content: 70.44

Gene sequence:

>1800_bases
ATGAACCCGCATCCGGGCCCCATCGCGCCCTCCGGCGCCGCACGCAATCACCCGACGAGAACCTACGACCTCGTGGTGAT
TGGCTCGGGAGCGGGTGGCCTCGCCACCGCCGTCACCGCCGCTCTCCTCGGCCTTGAGGTGGTCGTGGTGGAGAAGGATG
CCAAGATCGGCGGCACCACCGCCTGGTCCGGCGGATGGATGTGGATCCCGCGCAATCCGCTGGCTGTGGAGGCCGGGATC
GTCGAGGACATCAAGGCGCCGCGCACCTATCTGAAGGCCGAGCTGGGCAATGCCTATGACGAGGCCCTGGCCACCATGCT
GCTGGAGCAGGGTCCGCGCATGGTGGACTTCTTCCGCCGCAACACCAGCCTCGCCTTCGTGGACGGCAACGCCGTTCCCG
ATTTTCACGACACCTCGCCCGGTGCGGCCAAGGGCGGGCGCTCGCTGTGCGCGGCGCCGTTCGACGGACGGCTGCTCGGC
GCGCGCATTTGCGACCTGCGCGCGCCCCTTGACCTCATCTCGCCCTTCGGGATGGGCATCGCCTCAGGGCGCGACATGCT
CCATTTCCTGGAGGCCACGCGCAATGCCTCCTCCTTCACCCATGCCGCCGGGCGCATCCTGCGCCATTTCATCGACGTGG
CGCGCCACGGCCGCGGCATGAAGCTGGTCAACGGCAACGCCCTCATCGCCCGCCTGCTGAAATCGGCCGACGATCTGGGC
GTGACCATCCTGACCTCGTGCCCGGCCAGCGAGGTGCTGGTGGAAGAAGGGCGCGTGGCGGGCATCATCGCGGGCTCCGG
AGAAACGCTGCATGAGATCCACGCCCGGCGCGGCGTGGTGCTGGCGAGCGGCGGCTTTCCCCATGACCTCGCTCGCAAGG
CGGCGCTGTTTCCCCACGCACCGACCGGCCGCGAGCACTGGTCGGCGGCGCCGCAGACCAACAGCGGCGACGGCATTCGT
CTGGGGGAGGCCGCTGGCGGCTGCTTGCGTACGGACCTCTCGGACGCCGGCGCCTGGGCACCGGTGTCGCTGGTCCCACA
GGCCAGTGGCACCCCGGCGTCCTATCCCCACCTCGTCGAACGCGCGAAGCCCGGCCTCATCATGGTGCGCGCGGACGGGC
AACGTTTCACCAACGAAGCCGATTCCTACCACGACGTGATGCGCGCGCTACTGGCGGCAACGCCCCCTGGCGCGCCCGTG
GAAGCCTGGATGATCTGCGATCATGCCTTCCAGCGCCACTACGGCCTCGGCCGCACGCGGCCCCGGCCGTTCCCGCTGCG
CCCGTGGCTCGCCAGTGGATATCTGAAGCGCGGCAACAGCTTCGCCGAGCTGGCCCGCGCCTGCGGCATCGATGCCGACG
GGCTGGAACAGACCCTTGCGGATTATAACCGCGCCGCCGCGCGCGGCGAGGACCCCGCCTTCGGCCGCGGCTCCAGCCTC
TACAACCGGGTGCAGGGCGACGCGGCGCACCGGCCCAATCCCTGCGTCGCGCCCATCGCCCGCGGACCGTTTTATGCGGT
GAAGGTGGTGGCCGGCAGCCTCGGCACCTTCGCCGGCCTCGCCACCGACGCCCATGCCCGGGTGCTGGACGCTTCGGGCA
GCCCCATCGCCGGCCTCTATGCGGTGGGCAACGACATGTCGAGCATGATGGGCGGGCGCTATCCGGCGGGCGGCATCACC
CTCGGCCCGGCCATGACCTTCGGCTTCGTCGCCGCGCACCACGCCAGCGGCACCCCCCTTCCTTCCGACACCATCGACCG
CGGACAGCCGCGTCCGCCCGGAGAGTCCCATGCGTTATGA

Upstream 100 bases:

>100_bases
TGGGCGGGACCTATCCCGGCCCGGGCATCACCATCGGCCCGGCCATCACCTTCGCCTATCGCGCCGTGCGCCATGCCTGC
CAAGCCGGGGAGCAGCGGCC

Downstream 100 bases:

>100_bases
ACTTTTGTCCCTCACCATCCGCTTCGGCACGGTGCCTGCGGTGACCGCCGGCATCGAGGCCCATGCGAAGACGCCGGGCG
CCGGCACGCTGCTCGGCTGC

Product: putative FAD-binding dehydrogenase

Products: NA

Alternate protein names: 3-keto-Delta(4)-steroid Delta(1)-dehydrogenase; KSDD; 3-oxo-Delta(4)-steroid 1-dehydrogenase; KSTD [H]

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MNPHPGPIAPSGAARNHPTRTYDLVVIGSGAGGLATAVTAALLGLEVVVVEKDAKIGGTTAWSGGWMWIPRNPLAVEAGI
VEDIKAPRTYLKAELGNAYDEALATMLLEQGPRMVDFFRRNTSLAFVDGNAVPDFHDTSPGAAKGGRSLCAAPFDGRLLG
ARICDLRAPLDLISPFGMGIASGRDMLHFLEATRNASSFTHAAGRILRHFIDVARHGRGMKLVNGNALIARLLKSADDLG
VTILTSCPASEVLVEEGRVAGIIAGSGETLHEIHARRGVVLASGGFPHDLARKAALFPHAPTGREHWSAAPQTNSGDGIR
LGEAAGGCLRTDLSDAGAWAPVSLVPQASGTPASYPHLVERAKPGLIMVRADGQRFTNEADSYHDVMRALLAATPPGAPV
EAWMICDHAFQRHYGLGRTRPRPFPLRPWLASGYLKRGNSFAELARACGIDADGLEQTLADYNRAAARGEDPAFGRGSSL
YNRVQGDAAHRPNPCVAPIARGPFYAVKVVAGSLGTFAGLATDAHARVLDASGSPIAGLYAVGNDMSSMMGGRYPAGGIT
LGPAMTFGFVAAHHASGTPLPSDTIDRGQPRPPGESHAL

Sequences:

>Translated_599_residues
MNPHPGPIAPSGAARNHPTRTYDLVVIGSGAGGLATAVTAALLGLEVVVVEKDAKIGGTTAWSGGWMWIPRNPLAVEAGI
VEDIKAPRTYLKAELGNAYDEALATMLLEQGPRMVDFFRRNTSLAFVDGNAVPDFHDTSPGAAKGGRSLCAAPFDGRLLG
ARICDLRAPLDLISPFGMGIASGRDMLHFLEATRNASSFTHAAGRILRHFIDVARHGRGMKLVNGNALIARLLKSADDLG
VTILTSCPASEVLVEEGRVAGIIAGSGETLHEIHARRGVVLASGGFPHDLARKAALFPHAPTGREHWSAAPQTNSGDGIR
LGEAAGGCLRTDLSDAGAWAPVSLVPQASGTPASYPHLVERAKPGLIMVRADGQRFTNEADSYHDVMRALLAATPPGAPV
EAWMICDHAFQRHYGLGRTRPRPFPLRPWLASGYLKRGNSFAELARACGIDADGLEQTLADYNRAAARGEDPAFGRGSSL
YNRVQGDAAHRPNPCVAPIARGPFYAVKVVAGSLGTFAGLATDAHARVLDASGSPIAGLYAVGNDMSSMMGGRYPAGGIT
LGPAMTFGFVAAHHASGTPLPSDTIDRGQPRPPGESHAL
>Mature_599_residues
MNPHPGPIAPSGAARNHPTRTYDLVVIGSGAGGLATAVTAALLGLEVVVVEKDAKIGGTTAWSGGWMWIPRNPLAVEAGI
VEDIKAPRTYLKAELGNAYDEALATMLLEQGPRMVDFFRRNTSLAFVDGNAVPDFHDTSPGAAKGGRSLCAAPFDGRLLG
ARICDLRAPLDLISPFGMGIASGRDMLHFLEATRNASSFTHAAGRILRHFIDVARHGRGMKLVNGNALIARLLKSADDLG
VTILTSCPASEVLVEEGRVAGIIAGSGETLHEIHARRGVVLASGGFPHDLARKAALFPHAPTGREHWSAAPQTNSGDGIR
LGEAAGGCLRTDLSDAGAWAPVSLVPQASGTPASYPHLVERAKPGLIMVRADGQRFTNEADSYHDVMRALLAATPPGAPV
EAWMICDHAFQRHYGLGRTRPRPFPLRPWLASGYLKRGNSFAELARACGIDADGLEQTLADYNRAAARGEDPAFGRGSSL
YNRVQGDAAHRPNPCVAPIARGPFYAVKVVAGSLGTFAGLATDAHARVLDASGSPIAGLYAVGNDMSSMMGGRYPAGGIT
LGPAMTFGFVAAHHASGTPLPSDTIDRGQPRPPGESHAL

Specific function: Catalyzes the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3- ketosteroids. Is also involved in the formation of 1,4- androstadiene-3,17-dione (ADD) from 4-androstene-3,17-dione (AD) to [H]

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. 3-oxosteroid dehydrogenase subfamily [H]

Homologues:

Organism=Caenorhabditis elegans, GI71986328, Length=368, Percent_Identity=27.7173913043478, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.3.99.4 [H]

Molecular weight: Translated: 62727; Mature: 62727

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPHPGPIAPSGAARNHPTRTYDLVVIGSGAGGLATAVTAALLGLEVVVVEKDAKIGGTT
CCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCEEEEEEECCCCCCCCE
AWSGGWMWIPRNPLAVEAGIVEDIKAPRTYLKAELGNAYDEALATMLLEQGPRMVDFFRR
EECCCEEEECCCCCEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHC
NTSLAFVDGNAVPDFHDTSPGAAKGGRSLCAAPFDGRLLGARICDLRAPLDLISPFGMGI
CCEEEEEECCCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHCCCHHHHHHHCCCH
ASGRDMLHFLEATRNASSFTHAAGRILRHFIDVARHGRGMKLVNGNALIARLLKSADDLG
HCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCCC
VTILTSCPASEVLVEEGRVAGIIAGSGETLHEIHARRGVVLASGGFPHDLARKAALFPHA
EEEEECCCCHHHHHHCCCEEEEEECCCCHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCC
PTGREHWSAAPQTNSGDGIRLGEAAGGCLRTDLSDAGAWAPVSLVPQASGTPASYPHLVE
CCCHHHCCCCCCCCCCCCEEECCCCCCCEECCCCCCCCCCCEEECCCCCCCCCCCHHHHH
RAKPGLIMVRADGQRFTNEADSYHDVMRALLAATPPGAPVEAWMICDHAFQRHYGLGRTR
HCCCCEEEEEECCCHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCC
PRPFPLRPWLASGYLKRGNSFAELARACGIDADGLEQTLADYNRAAARGEDPAFGRGSSL
CCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
YNRVQGDAAHRPNPCVAPIARGPFYAVKVVAGSLGTFAGLATDAHARVLDASGSPIAGLY
HHHHCCCCCCCCCCCCCCCCCCCEEEEEEHHCCHHHHHHHCCCCCCEEEECCCCCCEEEE
AVGNDMSSMMGGRYPAGGITLGPAMTFGFVAAHHASGTPLPSDTIDRGQPRPPGESHAL
EECCCHHHHHCCCCCCCCEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNPHPGPIAPSGAARNHPTRTYDLVVIGSGAGGLATAVTAALLGLEVVVVEKDAKIGGTT
CCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCEEEEEEECCCCCCCCE
AWSGGWMWIPRNPLAVEAGIVEDIKAPRTYLKAELGNAYDEALATMLLEQGPRMVDFFRR
EECCCEEEECCCCCEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHC
NTSLAFVDGNAVPDFHDTSPGAAKGGRSLCAAPFDGRLLGARICDLRAPLDLISPFGMGI
CCEEEEEECCCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHCCCHHHHHHHCCCH
ASGRDMLHFLEATRNASSFTHAAGRILRHFIDVARHGRGMKLVNGNALIARLLKSADDLG
HCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCCC
VTILTSCPASEVLVEEGRVAGIIAGSGETLHEIHARRGVVLASGGFPHDLARKAALFPHA
EEEEECCCCHHHHHHCCCEEEEEECCCCHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCC
PTGREHWSAAPQTNSGDGIRLGEAAGGCLRTDLSDAGAWAPVSLVPQASGTPASYPHLVE
CCCHHHCCCCCCCCCCCCEEECCCCCCCEECCCCCCCCCCCEEECCCCCCCCCCCHHHHH
RAKPGLIMVRADGQRFTNEADSYHDVMRALLAATPPGAPVEAWMICDHAFQRHYGLGRTR
HCCCCEEEEEECCCHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCC
PRPFPLRPWLASGYLKRGNSFAELARACGIDADGLEQTLADYNRAAARGEDPAFGRGSSL
CCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
YNRVQGDAAHRPNPCVAPIARGPFYAVKVVAGSLGTFAGLATDAHARVLDASGSPIAGLY
HHHHCCCCCCCCCCCCCCCCCCCEEEEEEHHCCHHHHHHHCCCCCCEEEECCCCCCEEEE
AVGNDMSSMMGGRYPAGGITLGPAMTFGFVAAHHASGTPLPSDTIDRGQPRPPGESHAL
EECCCHHHHHCCCCCCCCEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA