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The map label for this gene is pcaQ [H]

Identifier: 154246626

GI number: 154246626

Start: 2975766

End: 2976677

Strand: Reverse

Name: pcaQ [H]

Synonym: Xaut_2686

Alternate gene names: 154246626

Gene position: 2976677-2975766 (Counterclockwise)

Preceding gene: 154246631

Following gene: 154246625

Centisome position: 56.07

GC content: 71.93

Gene sequence:

>912_bases
ATGATCGACGGACGCATGAAGCTGCGCCACATCGCCTGCTTCCTGGAGGTGGCGGCACGGTCCGGGTTCGGCCGCGCAGC
CGATGCGCTCGGCCTCACCCAGCCGGCGGTGTCGCGGGCCATCGCGGAACTGGAGGACATCCTCGGCGCGCCGCTGTTCG
AGCGCGGCCGCGGCGGCGCCGTGCTGACACCGCAGGGCATCGCCTTCCGCACCCATGCCGGGGCGGCCTTCGCGGAACTG
GGACGCGGCATCGACACGCTGCGACGGCCGGCCGCCGGCGATGTGGTGCTCAAAGTCGGCGCGCTGCCCACGGTGGCGGC
GCGGATCATGCCCGGGGCGATCCGGCGGGCGAAGGAGATGGGCCTCGATGCCACCATCGCCATCGAGGCCGGGTCCAACG
GCTGGCTTCTCGACCTGCTGACCGAGGGCCGCCTCGATCTGGTGGTGGGCCGCCTCGCCGAGCCCAAGGCCATGATGGGC
CTGACCTTCGAGCACCTGTATTCCGAGCCCATCGTCTTCGTGGCGCGGCGCGGCCACCCAGCCGACACCGGCCACCCGGT
GGGGCTCGTGGAGCTTGCCCGCCATCCCTTCATCATGCCGGGACCGGGCTCCATCATTCGTCCCGAGATCGACCGGCTGT
TCCTGATGGAAGGCCTGGCCGGCCCCGCCGAGCGCATCGAGACCACCGATGCGAGCTTCTCGCGGGCCTATGTCGGCGCC
AGTGACGCGGTGTGGGTCATCTCCCACGGGGTGGTGGCTGGCGATCTCGACGCCGGCACACTGGTGCGCCTCCCCCTGTC
CATGTCCATATCCGGCGGCCCGGTGGGCCTCACCACGCGGGCGGGACACGCTCCCCTGCCGCAGGCCGCGATCTTCCTCG
AGGCCCTGCGCGAGGTTGCCCGCGCCCTGTGA

Upstream 100 bases:

>100_bases
CGGCTGGCACCGTTTGGGATCGCCGCGAGAGTTTCATGTAGCGCATGATATGGAAAATGATATTTTTCTATCTATCCATG
CAATTTTGGTATGCATACCC

Downstream 100 bases:

>100_bases
GCCGGACCACACAACAGGCTTGACGCCAGAGCGCGCCGCAGTGGAGCTTGCGGCCCGTTTCGTTCCCGAGGAAGGCCCCA
GATCCATGAGCGTGTCCGTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Pca operon transcriptional activator [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MIDGRMKLRHIACFLEVAARSGFGRAADALGLTQPAVSRAIAELEDILGAPLFERGRGGAVLTPQGIAFRTHAGAAFAEL
GRGIDTLRRPAAGDVVLKVGALPTVAARIMPGAIRRAKEMGLDATIAIEAGSNGWLLDLLTEGRLDLVVGRLAEPKAMMG
LTFEHLYSEPIVFVARRGHPADTGHPVGLVELARHPFIMPGPGSIIRPEIDRLFLMEGLAGPAERIETTDASFSRAYVGA
SDAVWVISHGVVAGDLDAGTLVRLPLSMSISGGPVGLTTRAGHAPLPQAAIFLEALREVARAL

Sequences:

>Translated_303_residues
MIDGRMKLRHIACFLEVAARSGFGRAADALGLTQPAVSRAIAELEDILGAPLFERGRGGAVLTPQGIAFRTHAGAAFAEL
GRGIDTLRRPAAGDVVLKVGALPTVAARIMPGAIRRAKEMGLDATIAIEAGSNGWLLDLLTEGRLDLVVGRLAEPKAMMG
LTFEHLYSEPIVFVARRGHPADTGHPVGLVELARHPFIMPGPGSIIRPEIDRLFLMEGLAGPAERIETTDASFSRAYVGA
SDAVWVISHGVVAGDLDAGTLVRLPLSMSISGGPVGLTTRAGHAPLPQAAIFLEALREVARAL
>Mature_303_residues
MIDGRMKLRHIACFLEVAARSGFGRAADALGLTQPAVSRAIAELEDILGAPLFERGRGGAVLTPQGIAFRTHAGAAFAEL
GRGIDTLRRPAAGDVVLKVGALPTVAARIMPGAIRRAKEMGLDATIAIEAGSNGWLLDLLTEGRLDLVVGRLAEPKAMMG
LTFEHLYSEPIVFVARRGHPADTGHPVGLVELARHPFIMPGPGSIIRPEIDRLFLMEGLAGPAERIETTDASFSRAYVGA
SDAVWVISHGVVAGDLDAGTLVRLPLSMSISGGPVGLTTRAGHAPLPQAAIFLEALREVARAL

Specific function: Activates transcription of the pcaDCHGB operon for the catabolism of the phenolic compound protocatechuate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081904, Length=301, Percent_Identity=35.5481727574751, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1787601, Length=296, Percent_Identity=25.6756756756757, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789506, Length=195, Percent_Identity=28.7179487179487, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI157672245, Length=220, Percent_Identity=30, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788887, Length=175, Percent_Identity=28, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790399, Length=287, Percent_Identity=25.0871080139373, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788748, Length=171, Percent_Identity=26.9005847953216, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR012787
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31815; Mature: 31815

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDGRMKLRHIACFLEVAARSGFGRAADALGLTQPAVSRAIAELEDILGAPLFERGRGGA
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCHHCCCCCE
VLTPQGIAFRTHAGAAFAELGRGIDTLRRPAAGDVVLKVGALPTVAARIMPGAIRRAKEM
EECCCCCEEEECCCHHHHHHCCCHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHC
GLDATIAIEAGSNGWLLDLLTEGRLDLVVGRLAEPKAMMGLTFEHLYSEPIVFVARRGHP
CCCEEEEEEECCCCEEEEEECCCCHHHHHHCCCCCHHHHCCCHHHHHCCCEEEEEECCCC
ADTGHPVGLVELARHPFIMPGPGSIIRPEIDRLFLMEGLAGPAERIETTDASFSRAYVGA
CCCCCCCHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCCCHHEEECCC
SDAVWVISHGVVAGDLDAGTLVRLPLSMSISGGPVGLTTRAGHAPLPQAAIFLEALREVA
CCCEEEEECCEEEECCCCCEEEEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHH
RAL
HHC
>Mature Secondary Structure
MIDGRMKLRHIACFLEVAARSGFGRAADALGLTQPAVSRAIAELEDILGAPLFERGRGGA
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCHHCCCCCE
VLTPQGIAFRTHAGAAFAELGRGIDTLRRPAAGDVVLKVGALPTVAARIMPGAIRRAKEM
EECCCCCEEEECCCHHHHHHCCCHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHC
GLDATIAIEAGSNGWLLDLLTEGRLDLVVGRLAEPKAMMGLTFEHLYSEPIVFVARRGHP
CCCEEEEEEECCCCEEEEEECCCCHHHHHHCCCCCHHHHCCCHHHHHCCCEEEEEECCCC
ADTGHPVGLVELARHPFIMPGPGSIIRPEIDRLFLMEGLAGPAERIETTDASFSRAYVGA
CCCCCCCHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCCCHHEEECCC
SDAVWVISHGVVAGDLDAGTLVRLPLSMSISGGPVGLTTRAGHAPLPQAAIFLEALREVA
CCCEEEEECCEEEECCCCCEEEEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHH
RAL
HHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]