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The map label for this gene is dapA [H]

Identifier: 154246458

GI number: 154246458

Start: 2811463

End: 2812392

Strand: Direct

Name: dapA [H]

Synonym: Xaut_2517

Alternate gene names: 154246458

Gene position: 2811463-2812392 (Clockwise)

Preceding gene: 154246457

Following gene: 154246459

Centisome position: 52.96

GC content: 66.02

Gene sequence:

>930_bases
ATGAAGCCGGCAATCAGCTGGGAAGGCGTCTTCCCGGCCGTGACCACCCAGTTCCGCGACGACTATTCGCTCGATATCGA
CGCCACCGCCAAGGTGATGGAAGGCCTGATCCGCGACGGCGTGTCCGGCATGATCGTGTGCGGCACCGTGGGTGAGAACT
GCTCGCTCACCACCGCCGAGAAGATCCAGGTGATGGAAGCCGGCAAGGCGGTGGCCGCCGGCCGGGTGCCGGTGATCTGT
GGCATCGCCGAGTTCACCAGCGAATTCGCCATCGCCACCGCCAAGGAAGCCGCCAAGGTGGGCGTGGACGGCATCATGCT
CATGCCGGCGCTGGTGTATTCCTCCAAGCCCCATGAGACGGCGGCGCATTTCCGCACCGTCTCCAAGGCCACCGACCTGC
CGGTGATGATCTACAACAACCCGCCGGTCTACAAGAACGACGTGACCCCGGACGTGGTTGCTTCGCTCGTGGATTGCGAG
ACCATCGTCTGCTTCAAGGAAAGCTCGGGCGACACCCGCCGTTTCATCGACCTGCGCAACAAGGTGGGTGACCGCTTCAT
CATGTTCGCCGGCCTCGACGACGTGGTGGTGGAGAGCATCGCCATGGGCGCGCAGGGCTGGGTGTCGGGCATGTCCAACG
CCTTCCCGCGCGAGGGCGAGACCCTGTTCCGCCTCGCCCGCGCCGGCCGCTATGCGGAAGCCATGAAGCTCTATGAGTGG
TTCATGCCGCTGCTGCACCTCGATGCGCGCCCCGACCTCGTCCAGTGCATCAAGCTGTGCGAGCACATCATGGGCCGCGG
CACCTTCCTTACCCGCCCGCCGCGCCTGGCGCTGCTGGACCACGAGCGAGCCGAGGTGGAAGCGCTGATGGCGGCCGCTC
TCAAGACCCGTCCGGAACTGCCCGACGTGGGGCTGAAGGCCGCCGCCTGA

Upstream 100 bases:

>100_bases
GACCTGCGCAAGGCCGGCGCCGCCCTCTGATCCCTGAAACCCGCACGCGGACAGGGCAGGGCCTTGTCCGCACCCCTTAT
CGACACAAGGATGACATGAG

Downstream 100 bases:

>100_bases
GGAGGTCGAGGGCGAGGGTCTGCCCCTCGCCCTTACTCCCGCCATTCATGCCCCAGCCGACTGGAGCGATGGCGCAAGGA
GAGCCGGGGCCCAGCGCACG

Product: dihydrodipicolinate synthetase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MKPAISWEGVFPAVTTQFRDDYSLDIDATAKVMEGLIRDGVSGMIVCGTVGENCSLTTAEKIQVMEAGKAVAAGRVPVIC
GIAEFTSEFAIATAKEAAKVGVDGIMLMPALVYSSKPHETAAHFRTVSKATDLPVMIYNNPPVYKNDVTPDVVASLVDCE
TIVCFKESSGDTRRFIDLRNKVGDRFIMFAGLDDVVVESIAMGAQGWVSGMSNAFPREGETLFRLARAGRYAEAMKLYEW
FMPLLHLDARPDLVQCIKLCEHIMGRGTFLTRPPRLALLDHERAEVEALMAAALKTRPELPDVGLKAAA

Sequences:

>Translated_309_residues
MKPAISWEGVFPAVTTQFRDDYSLDIDATAKVMEGLIRDGVSGMIVCGTVGENCSLTTAEKIQVMEAGKAVAAGRVPVIC
GIAEFTSEFAIATAKEAAKVGVDGIMLMPALVYSSKPHETAAHFRTVSKATDLPVMIYNNPPVYKNDVTPDVVASLVDCE
TIVCFKESSGDTRRFIDLRNKVGDRFIMFAGLDDVVVESIAMGAQGWVSGMSNAFPREGETLFRLARAGRYAEAMKLYEW
FMPLLHLDARPDLVQCIKLCEHIMGRGTFLTRPPRLALLDHERAEVEALMAAALKTRPELPDVGLKAAA
>Mature_309_residues
MKPAISWEGVFPAVTTQFRDDYSLDIDATAKVMEGLIRDGVSGMIVCGTVGENCSLTTAEKIQVMEAGKAVAAGRVPVIC
GIAEFTSEFAIATAKEAAKVGVDGIMLMPALVYSSKPHETAAHFRTVSKATDLPVMIYNNPPVYKNDVTPDVVASLVDCE
TIVCFKESSGDTRRFIDLRNKVGDRFIMFAGLDDVVVESIAMGAQGWVSGMSNAFPREGETLFRLARAGRYAEAMKLYEW
FMPLLHLDARPDLVQCIKLCEHIMGRGTFLTRPPRLALLDHERAEVEALMAAALKTRPELPDVGLKAAA

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=232, Percent_Identity=25.8620689655172, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI87082415, Length=292, Percent_Identity=28.0821917808219, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1788823, Length=290, Percent_Identity=25.5172413793103, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1786463, Length=240, Percent_Identity=27.0833333333333, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789620, Length=262, Percent_Identity=22.9007633587786, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 33606; Mature: 33606

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPAISWEGVFPAVTTQFRDDYSLDIDATAKVMEGLIRDGVSGMIVCGTVGENCSLTTAE
CCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHH
KIQVMEAGKAVAAGRVPVICGIAEFTSEFAIATAKEAAKVGVDGIMLMPALVYSSKPHET
HHHHHHHCCHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHH
AAHFRTVSKATDLPVMIYNNPPVYKNDVTPDVVASLVDCETIVCFKESSGDTRRFIDLRN
HHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHH
KVGDRFIMFAGLDDVVVESIAMGAQGWVSGMSNAFPREGETLFRLARAGRYAEAMKLYEW
HCCCEEEEEECCHHHHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHH
FMPLLHLDARPDLVQCIKLCEHIMGRGTFLTRPPRLALLDHERAEVEALMAAALKTRPEL
HHHHHHCCCCCCHHHHHHHHHHHHCCCCEECCCCCEEEECCHHHHHHHHHHHHHHCCCCC
PDVGLKAAA
CCCCCCCCC
>Mature Secondary Structure
MKPAISWEGVFPAVTTQFRDDYSLDIDATAKVMEGLIRDGVSGMIVCGTVGENCSLTTAE
CCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHH
KIQVMEAGKAVAAGRVPVICGIAEFTSEFAIATAKEAAKVGVDGIMLMPALVYSSKPHET
HHHHHHHCCHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHH
AAHFRTVSKATDLPVMIYNNPPVYKNDVTPDVVASLVDCETIVCFKESSGDTRRFIDLRN
HHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHH
KVGDRFIMFAGLDDVVVESIAMGAQGWVSGMSNAFPREGETLFRLARAGRYAEAMKLYEW
HCCCEEEEEECCHHHHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHH
FMPLLHLDARPDLVQCIKLCEHIMGRGTFLTRPPRLALLDHERAEVEALMAAALKTRPEL
HHHHHHCCCCCCHHHHHHHHHHHHCCCCEECCCCCEEEECCHHHHHHHHHHHHHHCCCCC
PDVGLKAAA
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]