Click here to switch to the map view.

The map label for this gene is corA [H]

Identifier: 154246417

GI number: 154246417

Start: 2767997

End: 2768971

Strand: Direct

Name: corA [H]

Synonym: Xaut_2476

Alternate gene names: 154246417

Gene position: 2767997-2768971 (Clockwise)

Preceding gene: 154246415

Following gene: 154246420

Centisome position: 52.14

GC content: 63.38

Gene sequence:

>975_bases
ATGCTTGTTGCCTATGTGTTCAGCGATGGGGCCCTGAAGGGCAACCCTGTCGCTGGAGGGCCGATACCGCCTGACGCGGT
ATGGCTGGACCTGATCTCGCCCACCGAAGCCGATGATACCGCGGCTGAGGCGTTCGCCGGCATCTCTGTGCCGACCCGCG
AGGAGATGGGCGAAATCGAGCAATCGAGCCGCCTCTATATAGATGGCGAGGCACGATACATGACGGCCTCGCTGCTGTGC
GGGGCCGACACGCCGACACCGGTCATGCTGGCGGTCACCTTCATCTTGAGCCGCGGCCGGCTGATCACGGTGCGCTACGG
CGAGCCCCGCGCCTTTCCCTCCGTTTCCGGGCGCCTGGCCAAGTCCTGCCCCTCTTCAATTACCGGCGAAATCGTCCTCA
TCGACCTTCTCGAGGCGATCGTGGACCGGGCCGCCGACGTGCTGGAGCAGATCGGCGCCGACGTGGAGCGCATCTCCAAG
CGGATCTTCGATCGCGACCAGGGCAACGAGAACGCCAACCAGCGCTATCGCGCCATCCTCTCCCACATCGGTCGCAAGGA
AGGCCTGGTCTCCTACGCCCGCGAGAGCCTGGCCTCGCTGCAGCGACTTCTGTCCTTCCTCGGAACGGAGACCGAAGGGG
CGGCGGTGACCAAGGATTCCAAGTCCTCGGTCAAGTCCATGAGCCGGGACGTGTCGGGCCTGTCGGACTACGCGGCCTTC
ATCGGCGACAAGCTGCAGTTCCTGCTCGACGCCACCATCGGCCTCGTCAGCCTTGAGCAGAACAATATCATCAAGATCTT
CGCGGTGCTCTCGGTGGTGCTGATGCCGCCGACGCTGATCGCATCCATCTACGGCATGAACTTCCACAATATGCCGGAGC
TTGACTTTGCCTACGGCTATCCGCTGGCGCTCTGCGGCATGGTGGTGTCGGGCATCCTTCCCTACGTCTTCTTCAAGTGG
CGCCGTTGGCTCTGA

Upstream 100 bases:

>100_bases
CTGATCGCCAACGGACCCGGCGCGGGGCCGGGGCCACGGCGGCAGTTCCTCTGGCATTCCGCCGGGGCTACAACAGCCGG
GGAATTCGGGGACATGCCGC

Downstream 100 bases:

>100_bases
ACCCAAGCCCGCGCGCCGCCTGAGCGAAGCGCCTCAAGATCCCGCGCCGGCCTCACACATGCTGGCCGCCGTTGATGTGG
ATCTCCGCCCCGTTGAGGTA

Product: Mg2 transporter protein CorA family protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MLVAYVFSDGALKGNPVAGGPIPPDAVWLDLISPTEADDTAAEAFAGISVPTREEMGEIEQSSRLYIDGEARYMTASLLC
GADTPTPVMLAVTFILSRGRLITVRYGEPRAFPSVSGRLAKSCPSSITGEIVLIDLLEAIVDRAADVLEQIGADVERISK
RIFDRDQGNENANQRYRAILSHIGRKEGLVSYARESLASLQRLLSFLGTETEGAAVTKDSKSSVKSMSRDVSGLSDYAAF
IGDKLQFLLDATIGLVSLEQNNIIKIFAVLSVVLMPPTLIASIYGMNFHNMPELDFAYGYPLALCGMVVSGILPYVFFKW
RRWL

Sequences:

>Translated_324_residues
MLVAYVFSDGALKGNPVAGGPIPPDAVWLDLISPTEADDTAAEAFAGISVPTREEMGEIEQSSRLYIDGEARYMTASLLC
GADTPTPVMLAVTFILSRGRLITVRYGEPRAFPSVSGRLAKSCPSSITGEIVLIDLLEAIVDRAADVLEQIGADVERISK
RIFDRDQGNENANQRYRAILSHIGRKEGLVSYARESLASLQRLLSFLGTETEGAAVTKDSKSSVKSMSRDVSGLSDYAAF
IGDKLQFLLDATIGLVSLEQNNIIKIFAVLSVVLMPPTLIASIYGMNFHNMPELDFAYGYPLALCGMVVSGILPYVFFKW
RRWL
>Mature_324_residues
MLVAYVFSDGALKGNPVAGGPIPPDAVWLDLISPTEADDTAAEAFAGISVPTREEMGEIEQSSRLYIDGEARYMTASLLC
GADTPTPVMLAVTFILSRGRLITVRYGEPRAFPSVSGRLAKSCPSSITGEIVLIDLLEAIVDRAADVLEQIGADVERISK
RIFDRDQGNENANQRYRAILSHIGRKEGLVSYARESLASLQRLLSFLGTETEGAAVTKDSKSSVKSMSRDVSGLSDYAAF
IGDKLQFLLDATIGLVSLEQNNIIKIFAVLSVVLMPPTLIASIYGMNFHNMPELDFAYGYPLALCGMVVSGILPYVFFKW
RRWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=326, Percent_Identity=33.1288343558282, Blast_Score=176, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 35269; Mature: 35269

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVAYVFSDGALKGNPVAGGPIPPDAVWLDLISPTEADDTAAEAFAGISVPTREEMGEIE
CEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHH
QSSRLYIDGEARYMTASLLCGADTPTPVMLAVTFILSRGRLITVRYGEPRAFPSVSGRLA
HCCEEEECCCCCEEEHHHEECCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHH
KSCPSSITGEIVLIDLLEAIVDRAADVLEQIGADVERISKRIFDRDQGNENANQRYRAIL
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHH
SHIGRKEGLVSYARESLASLQRLLSFLGTETEGAAVTKDSKSSVKSMSRDVSGLSDYAAF
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHH
IGDKLQFLLDATIGLVSLEQNNIIKIFAVLSVVLMPPTLIASIYGMNFHNMPELDFAYGY
HHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHCCC
PLALCGMVVSGILPYVFFKWRRWL
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLVAYVFSDGALKGNPVAGGPIPPDAVWLDLISPTEADDTAAEAFAGISVPTREEMGEIE
CEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHH
QSSRLYIDGEARYMTASLLCGADTPTPVMLAVTFILSRGRLITVRYGEPRAFPSVSGRLA
HCCEEEECCCCCEEEHHHEECCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHH
KSCPSSITGEIVLIDLLEAIVDRAADVLEQIGADVERISKRIFDRDQGNENANQRYRAIL
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHH
SHIGRKEGLVSYARESLASLQRLLSFLGTETEGAAVTKDSKSSVKSMSRDVSGLSDYAAF
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHH
IGDKLQFLLDATIGLVSLEQNNIIKIFAVLSVVLMPPTLIASIYGMNFHNMPELDFAYGY
HHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHCCC
PLALCGMVVSGILPYVFFKWRRWL
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]