| Definition | Xanthobacter autotrophicus Py2 chromosome, complete genome. |
|---|---|
| Accession | NC_009720 |
| Length | 5,308,934 |
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The map label for this gene is gno [H]
Identifier: 154246378
GI number: 154246378
Start: 2724178
End: 2724945
Strand: Direct
Name: gno [H]
Synonym: Xaut_2437
Alternate gene names: 154246378
Gene position: 2724178-2724945 (Clockwise)
Preceding gene: 154246366
Following gene: 154246379
Centisome position: 51.31
GC content: 66.67
Gene sequence:
>768_bases GTGTCCCTCAAATTGTTCGACCTCAGCGGCAAGCGTGCACTGGTCACCGGATCGGGGCAGGGCATAGGCCTTTCGCTGGC CGAGGGCCTGGGCCGCGCTGGCGCCCGCGTGGTCATCAATGGCCGTGACGAGGCCAAGCTCGCCAGGGCCGCCGAGCAGC TTTCCGCGCAGGGCATCGCCGTGGAGCAGTCCGCCTTTGATGTGACCGATCCCAAGGCGGTGGTCGAGGCCGTGGACGCC ATCGAAAAGGACCATGGCCCCATCGATATTCTCGTCAACAATGCGGGCATCCAGCGCCGCGCGCCGCTGGAGGAGTTCGA GGTCGACACCTGGCGCGAGGTGATGCGCACCAATCTCGACAGCGTGTTCTTCGTGGGCCAGGCGGTGGCCCGCCACATGA TCAAGCGCGGGCGCGGCAAGATCATCAATATCGGCAGCCTCATGAGCGCGGCGGCGCGCTATTCGGTGGCGCCCTATACG GCGGCCAAGGGCGGCGTGCGCAACCTCACCTTCGGCATGTGCACCGACTGGGCCCGCCACGGCCTCCAGATTAATGCGGT GGGGCCGGGCTATTTCGCCACCCCGCTCAATCAGGCGCTGGTGGAAAACCCCGATTTCGACCGCTGGCTGAAGGCCCGCA CCCCCGCCGGCCGCTGGGGCAGGGTGGAGGAATTGCAGGGCGCCGTGATCTTCCTCGCCTCGCCCGGATCCGATTTCGTC AACGGCCAGATTCTCTACGTGGACGGCGGCGTTCTGGCGACGCTTTGA
Upstream 100 bases:
>100_bases GTCCGCTTTGCCTCTTGTCATGTTACCGATATCATGAAATACAGTTCGCGCAAGAGCGGCGCACATTTCTGATGCGCTCC GGCATGGGGAGGAGGACAGC
Downstream 100 bases:
>100_bases GTCTCGCGCGCGGCATCCCTCATCCGGGCGCGAAGACCCGGGGATGCAGCCTTGAAGTAAAAATCGACCAAAATCGGGAG GACCTGACCCATGCGAAAGA
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 5-keto-D-gluconate 5-reductase [H]
Number of amino acids: Translated: 255; Mature: 254
Protein sequence:
>255_residues MSLKLFDLSGKRALVTGSGQGIGLSLAEGLGRAGARVVINGRDEAKLARAAEQLSAQGIAVEQSAFDVTDPKAVVEAVDA IEKDHGPIDILVNNAGIQRRAPLEEFEVDTWREVMRTNLDSVFFVGQAVARHMIKRGRGKIINIGSLMSAAARYSVAPYT AAKGGVRNLTFGMCTDWARHGLQINAVGPGYFATPLNQALVENPDFDRWLKARTPAGRWGRVEELQGAVIFLASPGSDFV NGQILYVDGGVLATL
Sequences:
>Translated_255_residues MSLKLFDLSGKRALVTGSGQGIGLSLAEGLGRAGARVVINGRDEAKLARAAEQLSAQGIAVEQSAFDVTDPKAVVEAVDA IEKDHGPIDILVNNAGIQRRAPLEEFEVDTWREVMRTNLDSVFFVGQAVARHMIKRGRGKIINIGSLMSAAARYSVAPYT AAKGGVRNLTFGMCTDWARHGLQINAVGPGYFATPLNQALVENPDFDRWLKARTPAGRWGRVEELQGAVIFLASPGSDFV NGQILYVDGGVLATL >Mature_254_residues SLKLFDLSGKRALVTGSGQGIGLSLAEGLGRAGARVVINGRDEAKLARAAEQLSAQGIAVEQSAFDVTDPKAVVEAVDAI EKDHGPIDILVNNAGIQRRAPLEEFEVDTWREVMRTNLDSVFFVGQAVARHMIKRGRGKIINIGSLMSAAARYSVAPYTA AKGGVRNLTFGMCTDWARHGLQINAVGPGYFATPLNQALVENPDFDRWLKARTPAGRWGRVEELQGAVIFLASPGSDFVN GQILYVDGGVLATL
Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=33.9920948616601, Blast_Score=127, Evalue=1e-29, Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=33.59375, Blast_Score=124, Evalue=6e-29, Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=30.2904564315353, Blast_Score=108, Evalue=6e-24, Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=27.3092369477912, Blast_Score=104, Evalue=6e-23, Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=32.1285140562249, Blast_Score=104, Evalue=1e-22, Organism=Homo sapiens, GI4503301, Length=224, Percent_Identity=29.9107142857143, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=28.8, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=28.0487804878049, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI59889578, Length=224, Percent_Identity=32.5892857142857, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI66933014, Length=249, Percent_Identity=29.3172690763052, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI7706318, Length=203, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=8e-18, Organism=Homo sapiens, GI20149619, Length=190, Percent_Identity=30, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=26.5873015873016, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI209862901, Length=256, Percent_Identity=28.125, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI19923983, Length=256, Percent_Identity=28.125, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI4758504, Length=268, Percent_Identity=29.1044776119403, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI4503817, Length=200, Percent_Identity=26, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=27.0718232044199, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI4502599, Length=155, Percent_Identity=32.258064516129, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI7705855, Length=209, Percent_Identity=28.2296650717703, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI31542939, Length=215, Percent_Identity=28.3720930232558, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI4504505, Length=192, Percent_Identity=28.6458333333333, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=26.9035532994924, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI4502601, Length=171, Percent_Identity=28.6549707602339, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=51.6129032258064, Blast_Score=268, Evalue=3e-73, Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=41.7322834645669, Blast_Score=180, Evalue=7e-47, Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=35.4330708661417, Blast_Score=160, Evalue=6e-41, Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=36.1788617886179, Blast_Score=153, Evalue=1e-38, Organism=Escherichia coli, GI1788459, Length=242, Percent_Identity=33.0578512396694, Blast_Score=130, Evalue=6e-32, Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=30.6772908366534, Blast_Score=105, Evalue=2e-24, Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=31.3008130081301, Blast_Score=104, Evalue=5e-24, Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=31.9838056680162, Blast_Score=98, Evalue=5e-22, Organism=Escherichia coli, GI1786812, Length=253, Percent_Identity=26.4822134387352, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1789057, Length=251, Percent_Identity=27.0916334661355, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=29.6747967479675, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1787820, Length=178, Percent_Identity=28.6516853932584, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=26.1044176706827, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1787526, Length=213, Percent_Identity=24.8826291079812, Blast_Score=62, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=33.6032388663968, Blast_Score=132, Evalue=1e-31, Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=32.7935222672065, Blast_Score=114, Evalue=6e-26, Organism=Caenorhabditis elegans, GI17560150, Length=257, Percent_Identity=30.7392996108949, Blast_Score=113, Evalue=8e-26, Organism=Caenorhabditis elegans, GI71994604, Length=245, Percent_Identity=31.0204081632653, Blast_Score=107, Evalue=7e-24, Organism=Caenorhabditis elegans, GI17536025, Length=251, Percent_Identity=32.6693227091633, Blast_Score=107, Evalue=8e-24, Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=28.8617886178862, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=31.8725099601594, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=31.4393939393939, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17561272, Length=250, Percent_Identity=33.6, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=29.8804780876494, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17562990, Length=257, Percent_Identity=29.5719844357977, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=30.7984790874525, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=29.2307692307692, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=30.6818181818182, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=25.8064516129032, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=29.6577946768061, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=30.0395256916996, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=29.1828793774319, Blast_Score=97, Evalue=9e-21, Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=28.0769230769231, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=30.0380228136882, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=26.8939393939394, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=27.4436090225564, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=28.1368821292776, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17565030, Length=256, Percent_Identity=30.078125, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17563726, Length=257, Percent_Identity=27.2373540856031, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=28.0769230769231, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=27.4131274131274, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=28.735632183908, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=25.5208333333333, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI193203115, Length=190, Percent_Identity=25.7894736842105, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17538182, Length=255, Percent_Identity=28.6274509803922, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI71997099, Length=236, Percent_Identity=27.5423728813559, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI212646214, Length=191, Percent_Identity=26.7015706806283, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17564282, Length=158, Percent_Identity=26.5822784810127, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI32563809, Length=218, Percent_Identity=24.7706422018349, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17507613, Length=218, Percent_Identity=24.7706422018349, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI71982365, Length=189, Percent_Identity=25.3968253968254, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17555612, Length=218, Percent_Identity=26.1467889908257, Blast_Score=64, Evalue=7e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=252, Percent_Identity=25, Blast_Score=72, Evalue=9e-14, Organism=Drosophila melanogaster, GI24639444, Length=251, Percent_Identity=35.0597609561753, Blast_Score=122, Evalue=2e-28, Organism=Drosophila melanogaster, GI28571526, Length=245, Percent_Identity=33.0612244897959, Blast_Score=115, Evalue=3e-26, Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=32, Blast_Score=115, Evalue=4e-26, Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=33.8709677419355, Blast_Score=110, Evalue=7e-25, Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=29.4117647058824, Blast_Score=104, Evalue=6e-23, Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=26.9076305220884, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=29.3877551020408, Blast_Score=93, Evalue=1e-19, Organism=Drosophila melanogaster, GI24644337, Length=250, Percent_Identity=30.8, Blast_Score=92, Evalue=4e-19, Organism=Drosophila melanogaster, GI21358495, Length=222, Percent_Identity=29.7297297297297, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24640492, Length=202, Percent_Identity=26.2376237623762, Blast_Score=84, Evalue=8e-17, Organism=Drosophila melanogaster, GI24581726, Length=195, Percent_Identity=28.2051282051282, Blast_Score=84, Evalue=8e-17, Organism=Drosophila melanogaster, GI281364892, Length=166, Percent_Identity=33.1325301204819, Blast_Score=82, Evalue=2e-16, Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=29.6875, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=29.6875, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI28574402, Length=198, Percent_Identity=29.2929292929293, Blast_Score=78, Evalue=7e-15, Organism=Drosophila melanogaster, GI24584744, Length=198, Percent_Identity=29.2929292929293, Blast_Score=78, Evalue=7e-15, Organism=Drosophila melanogaster, GI24640442, Length=203, Percent_Identity=30.0492610837438, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24584752, Length=196, Percent_Identity=29.0816326530612, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI21355631, Length=167, Percent_Identity=29.3413173652695, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI21357673, Length=221, Percent_Identity=26.6968325791855, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI21356301, Length=200, Percent_Identity=28, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI18859837, Length=186, Percent_Identity=31.7204301075269, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI17737361, Length=252, Percent_Identity=27.3809523809524, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24580925, Length=208, Percent_Identity=25.9615384615385, Blast_Score=66, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.69 [H]
Molecular weight: Translated: 27289; Mature: 27157
Theoretical pI: Translated: 8.46; Mature: 8.46
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSLKLFDLSGKRALVTGSGQGIGLSLAEGLGRAGARVVINGRDEAKLARAAEQLSAQGIA CCEEEEECCCCEEEEECCCCCCCHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCEE VEQSAFDVTDPKAVVEAVDAIEKDHGPIDILVNNAGIQRRAPLEEFEVDTWREVMRTNLD EECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHCHHHHHHHHHCCCH SVFFVGQAVARHMIKRGRGKIINIGSLMSAAARYSVAPYTAAKGGVRNLTFGMCTDWARH HHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHC GLQINAVGPGYFATPLNQALVENPDFDRWLKARTPAGRWGRVEELQGAVIFLASPGSDFV CEEEEEECCCHHHCCHHHHHHCCCCHHHHHHHCCCCCCCCCHHHCCCEEEEEECCCCCHH NGQILYVDGGVLATL CCEEEEECCCEEECC >Mature Secondary Structure SLKLFDLSGKRALVTGSGQGIGLSLAEGLGRAGARVVINGRDEAKLARAAEQLSAQGIA CEEEEECCCCEEEEECCCCCCCHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCEE VEQSAFDVTDPKAVVEAVDAIEKDHGPIDILVNNAGIQRRAPLEEFEVDTWREVMRTNLD EECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHCHHHHHHHHHCCCH SVFFVGQAVARHMIKRGRGKIINIGSLMSAAARYSVAPYTAAKGGVRNLTFGMCTDWARH HHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHC GLQINAVGPGYFATPLNQALVENPDFDRWLKARTPAGRWGRVEELQGAVIFLASPGSDFV CEEEEEECCCHHHCCHHHHHHCCCCHHHHHHHCCCCCCCCCHHHCCCEEEEEECCCCCHH NGQILYVDGGVLATL CCEEEEECCCEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7751271 [H]