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The map label for this gene is moaE [H]

Identifier: 154246289

GI number: 154246289

Start: 2621577

End: 2622050

Strand: Direct

Name: moaE [H]

Synonym: Xaut_2347

Alternate gene names: 154246289

Gene position: 2621577-2622050 (Clockwise)

Preceding gene: 154246288

Following gene: 154246290

Centisome position: 49.38

GC content: 73.0

Gene sequence:

>474_bases
GTGTTTTCCGTCCGCATCCAGGAGGCGCCGTTTGATGCGGCCGCCGAAGCGGCGCGCCTCGCGCAGGGGCGCACCGATGT
CGGTGGCATCGTCACCTTCACCGGCCTGTGCCGGGCCGATGCGGGAGCGGACGGGACGGGGCTCGCGGCGCTCACGCTGG
AGCATTATCCCGGCATGGCGGAAGAGGAGATCGAGCGCCATGTGGCCGAGGCCCGCGCGCGCTGGCCGTTGCTGGGCGCC
ATCGTGGTGCACCGGCACGGGCGTCTGGTGCCGGGCGACCCCATCGTGTTCGTCGCCACCGCCTCGGCGCACCGGGCGGC
GGCTTTTGCCGCGGCCGAATTCCTCATGGACTGGCTGAAGACCAGCGCCCCCTTCTGGAAGAAGGAGGAGCGGGCGGACG
GTCCCGACGCCGGCGGATGGGTCGAGGCCAAGGCCAGCGACGACGCGGCGGCGGACCGCTGGGCGCGGGACTGA

Upstream 100 bases:

>100_bases
GGTGCGCGCCGCCCTCGATCGGCGCCACGTGAAGCCGGATGCATCCCTCGCCGGGGTGCGGGAAGTGGCCTTCTTCCCGC
CCATGACCGGAGGCTGAGCC

Downstream 100 bases:

>100_bases
CCGAGCCCATTCCTCGATCCGGCTCCGCCCTCAGGCGAGGAAGGCACCGTGTACCCAGCCCGATTTCTGCGCATCCGAAT
GCGACGCGGCCGGTGCTGGC

Product: molybdopterin biosynthesis MoaE protein

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MFSVRIQEAPFDAAAEAARLAQGRTDVGGIVTFTGLCRADAGADGTGLAALTLEHYPGMAEEEIERHVAEARARWPLLGA
IVVHRHGRLVPGDPIVFVATASAHRAAAFAAAEFLMDWLKTSAPFWKKEERADGPDAGGWVEAKASDDAAADRWARD

Sequences:

>Translated_157_residues
MFSVRIQEAPFDAAAEAARLAQGRTDVGGIVTFTGLCRADAGADGTGLAALTLEHYPGMAEEEIERHVAEARARWPLLGA
IVVHRHGRLVPGDPIVFVATASAHRAAAFAAAEFLMDWLKTSAPFWKKEERADGPDAGGWVEAKASDDAAADRWARD
>Mature_157_residues
MFSVRIQEAPFDAAAEAARLAQGRTDVGGIVTFTGLCRADAGADGTGLAALTLEHYPGMAEEEIERHVAEARARWPLLGA
IVVHRHGRLVPGDPIVFVATASAHRAAAFAAAEFLMDWLKTSAPFWKKEERADGPDAGGWVEAKASDDAAADRWARD

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=102, Percent_Identity=35.2941176470588, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1787003, Length=145, Percent_Identity=51.7241379310345, Blast_Score=136, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17509279, Length=114, Percent_Identity=35.0877192982456, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 16766; Mature: 16766

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSVRIQEAPFDAAAEAARLAQGRTDVGGIVTFTGLCRADAGADGTGLAALTLEHYPGMA
CCEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCC
EEEIERHVAEARARWPLLGAIVVHRHGRLVPGDPIVFVATASAHRAAAFAAAEFLMDWLK
HHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
TSAPFWKKEERADGPDAGGWVEAKASDDAAADRWARD
HCCCCCCCHHCCCCCCCCCEEEECCCCCHHHHHCCCC
>Mature Secondary Structure
MFSVRIQEAPFDAAAEAARLAQGRTDVGGIVTFTGLCRADAGADGTGLAALTLEHYPGMA
CCEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCC
EEEIERHVAEARARWPLLGAIVVHRHGRLVPGDPIVFVATASAHRAAAFAAAEFLMDWLK
HHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
TSAPFWKKEERADGPDAGGWVEAKASDDAAADRWARD
HCCCCCCCHHCCCCCCCCCEEEECCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]