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The map label for this gene is pdtaS [H]

Identifier: 154246275

GI number: 154246275

Start: 2606152

End: 2607282

Strand: Reverse

Name: pdtaS [H]

Synonym: Xaut_2333

Alternate gene names: 154246275

Gene position: 2607282-2606152 (Counterclockwise)

Preceding gene: 154246276

Following gene: 154246271

Centisome position: 49.11

GC content: 70.2

Gene sequence:

>1131_bases
ATGGACGGCTCCGCCCCCGAACCGTCCGCCCCGCTCCAGGACGGCACGTCCGCGCCGCCGGCGCCGCTGCGCGTGCTGTA
TGTGGACGATGACCCGGCGCTGGGCCGCCTGGTGCAGCGCCAGCTCGGGCGGCTCGGGTTCGAGGTGGTGCTGGCGGGCT
CGGGGGAGGCGGGCCTTGCCCTCGTCGCCGCGGAGCGTTTCGACGTGGTGGCCCTTGACCACTACATGCCGGGCCAGGAC
GGTATCACCACCCTGCGCGCCATCTGTGCTCTCGATCGTCCCCCACCAGTGGTCTACGTCACCGGCGCCCAGGACGGCCG
GCTCGCGGTGGCGGCGTTGAAGGCGGGGGCGGCCGACTATGTGGTCAAGGAAATCCAGGCCGATTTCATCGAGCTGCTGC
GTGCCGCCTTCGTGGCGGCGGTGGAGCAGGTGCGCATGCGCCGCGCCCATGAGGCGGCGGAAGCGGAGATCCGCGCCGCC
CGCGACCGCTTCGAGGCGCTGGCGGCCGAGCGCGCCCTGCTGCTGCGCGAGATGAACCACCGGGTGGGCAATTCGCTGCA
GATCATCGTGTCGCTGCTAAACGTGCAGGCCAGCGCCACCGAGGACGGACGGGTGAAGGAGGCGCTGAACTCCGCCCGCA
ACCGGGTTTCGGCCGTGGCCCAGGTGCATCGCCGGCTCTACACCTCCGACCAGATCGCCACCGTCGCCCTCGACCAATAT
ATCGGCTCGCTGCTGGACGACCTCCAAGTGTCGGCCCACCGGGACCTTGGCGGCATCACCATCACGCTCGATGCCGATCC
CATCCACATCGATCCCGACCGCGCCGTGGCGGTGGGCATCATCGCCACCGAACTGGTGATCAATGCCATGAAATACGCCT
ATCCCGGCGGCGAGGGAGCCATACGGGTGGCGCTGAAGCGGCAGGGCGAGCGCATCGATTTCGCGGTGGAGGATGACGGG
GCGGGCATGGCGGCCGCGAAAGCCGCGGAGACCGGCTCGACCTCGTCCACCGGTCTCGGCACCCGTATCGTGCGGGCCAT
GTCCACCAAGCTGGGCTGCGAGCCCACCCTGGATGCGCGGGACAAGGGCACCTGCGTGCGGCTCACCTTCCGCCTCGCCG
AACGCTCCTGA

Upstream 100 bases:

>100_bases
ATGTCTATGTGACCAAGCCGGTCAACTACGAGAATTTCGCCAACGCCATCCGCCAGCTCGGGCTGTTCTTCTCCGTCATC
CAGGTTCCGGAGACAGACTG

Downstream 100 bases:

>100_bases
CGGCCCCGCTGGGCGGCGCCGTCAGGCATGATTCAGATGCGCGGAACGATGATCAGCCGTTCCACCGGCTTGCCGCCGAG
GAGGTGGGAGGTGACGATCT

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MDGSAPEPSAPLQDGTSAPPAPLRVLYVDDDPALGRLVQRQLGRLGFEVVLAGSGEAGLALVAAERFDVVALDHYMPGQD
GITTLRAICALDRPPPVVYVTGAQDGRLAVAALKAGAADYVVKEIQADFIELLRAAFVAAVEQVRMRRAHEAAEAEIRAA
RDRFEALAAERALLLREMNHRVGNSLQIIVSLLNVQASATEDGRVKEALNSARNRVSAVAQVHRRLYTSDQIATVALDQY
IGSLLDDLQVSAHRDLGGITITLDADPIHIDPDRAVAVGIIATELVINAMKYAYPGGEGAIRVALKRQGERIDFAVEDDG
AGMAAAKAAETGSTSSTGLGTRIVRAMSTKLGCEPTLDARDKGTCVRLTFRLAERS

Sequences:

>Translated_376_residues
MDGSAPEPSAPLQDGTSAPPAPLRVLYVDDDPALGRLVQRQLGRLGFEVVLAGSGEAGLALVAAERFDVVALDHYMPGQD
GITTLRAICALDRPPPVVYVTGAQDGRLAVAALKAGAADYVVKEIQADFIELLRAAFVAAVEQVRMRRAHEAAEAEIRAA
RDRFEALAAERALLLREMNHRVGNSLQIIVSLLNVQASATEDGRVKEALNSARNRVSAVAQVHRRLYTSDQIATVALDQY
IGSLLDDLQVSAHRDLGGITITLDADPIHIDPDRAVAVGIIATELVINAMKYAYPGGEGAIRVALKRQGERIDFAVEDDG
AGMAAAKAAETGSTSSTGLGTRIVRAMSTKLGCEPTLDARDKGTCVRLTFRLAERS
>Mature_376_residues
MDGSAPEPSAPLQDGTSAPPAPLRVLYVDDDPALGRLVQRQLGRLGFEVVLAGSGEAGLALVAAERFDVVALDHYMPGQD
GITTLRAICALDRPPPVVYVTGAQDGRLAVAALKAGAADYVVKEIQADFIELLRAAFVAAVEQVRMRRAHEAAEAEIRAA
RDRFEALAAERALLLREMNHRVGNSLQIIVSLLNVQASATEDGRVKEALNSARNRVSAVAQVHRRLYTSDQIATVALDQY
IGSLLDDLQVSAHRDLGGITITLDADPIHIDPDRAVAVGIIATELVINAMKYAYPGGEGAIRVALKRQGERIDFAVEDDG
AGMAAAKAAETGSTSSTGLGTRIVRAMSTKLGCEPTLDARDKGTCVRLTFRLAERS

Specific function: Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=107, Percent_Identity=39.2523364485981, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788550, Length=131, Percent_Identity=33.587786259542, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR022066
- InterPro:   IPR011495
- InterPro:   IPR005467 [H]

Pfam domain/function: PF12282 H_kinase_N; PF02518 HATPase_c; PF07568 HisKA_2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39992; Mature: 39992

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGSAPEPSAPLQDGTSAPPAPLRVLYVDDDPALGRLVQRQLGRLGFEVVLAGSGEAGLA
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCEE
LVAAERFDVVALDHYMPGQDGITTLRAICALDRPPPVVYVTGAQDGRLAVAALKAGAADY
EEEECCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEHHCCHHHH
VVKEIQADFIELLRAAFVAAVEQVRMRRAHEAAEAEIRAARDRFEALAAERALLLREMNH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVGNSLQIIVSLLNVQASATEDGRVKEALNSARNRVSAVAQVHRRLYTSDQIATVALDQY
HHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
IGSLLDDLQVSAHRDLGGITITLDADPIHIDPDRAVAVGIIATELVINAMKYAYPGGEGA
HHHHHHHHHHHHCCCCCCEEEEECCCCEEECCCCCEEHHHHHHHHHHHHHHHCCCCCCCE
IRVALKRQGERIDFAVEDDGAGMAAAKAAETGSTSSTGLGTRIVRAMSTKLGCEPTLDAR
EEEEEECCCCEEEEEEECCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
DKGTCVRLTFRLAERS
CCCCEEEEEEEECCCC
>Mature Secondary Structure
MDGSAPEPSAPLQDGTSAPPAPLRVLYVDDDPALGRLVQRQLGRLGFEVVLAGSGEAGLA
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCEE
LVAAERFDVVALDHYMPGQDGITTLRAICALDRPPPVVYVTGAQDGRLAVAALKAGAADY
EEEECCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEHHCCHHHH
VVKEIQADFIELLRAAFVAAVEQVRMRRAHEAAEAEIRAARDRFEALAAERALLLREMNH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVGNSLQIIVSLLNVQASATEDGRVKEALNSARNRVSAVAQVHRRLYTSDQIATVALDQY
HHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
IGSLLDDLQVSAHRDLGGITITLDADPIHIDPDRAVAVGIIATELVINAMKYAYPGGEGA
HHHHHHHHHHHHCCCCCCEEEEECCCCEEECCCCCEEHHHHHHHHHHHHHHHCCCCCCCE
IRVALKRQGERIDFAVEDDGAGMAAAKAAETGSTSSTGLGTRIVRAMSTKLGCEPTLDAR
EEEEEECCCCEEEEEEECCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
DKGTCVRLTFRLAERS
CCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]