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The map label for this gene is katA [H]

Identifier: 154246263

GI number: 154246263

Start: 2593438

End: 2594943

Strand: Reverse

Name: katA [H]

Synonym: Xaut_2321

Alternate gene names: 154246263

Gene position: 2594943-2593438 (Counterclockwise)

Preceding gene: 154246267

Following gene: 154246261

Centisome position: 48.88

GC content: 65.01

Gene sequence:

>1506_bases
ATGACGCGACCCACACTCACCACCACGGCCGGCAACCCCATCGCCGACAATCAGAATTCGCTGACCGCCGGCGAGCGCGG
CCCGGTGCTGATGCAGGACTACCAGCTGCTCGAGAAGCTGGCGCACCAGAACCGCGAGCGCATCCCCGAGCGCGTGGTGC
ATGCCAAGGGCTGGGGCGCTCACGGCACCCTCACCATCACCGGCGACATCTCGAAATACACCAAGGCGGCGGCGCTCCAG
CCCGGCGCGCAGACCCCCATGATCGCCCGCTTCTCCACCGTGGCCGGTGAGCTGGGCGCGGCGGATGCCGAGCGCGACGT
GCGCGGCTTCGCCCTCAAATTCTATACGCCGGAAGGCAACTGGGACCTCGTAGGCAACAACACTCCGGTGTTTTTCGTCC
GCGACCCCTACAAGTTCCCGGACTTCATCCACACCCAGAAGCGCCACCCCAAGACCAACCTGCGCTCGCCCACCGCCATG
TGGGACTTCTGGTCCCTGTCACCGGAGAGCCTGCACCAGGTGACCATCCTGTTCTCCGACCGCGGCCTGCCCGTGGGCGT
GCGGAACATGAACGGCTACGGCTCGCACACCTATTCCTTCGTCAACGCGGCTGGCGAGCGGTTCTGGGTGAAGTTCCACT
TCAAGACGCTTCAGGGCCATGAGCACTGGACCAATGCGGAGGCCACGCAGGTGGTGGGCCGCACCCGCGAATCCACGCAG
GAAGACCTGTTCGGCGCCATCGAAGCCGGCAACTTCCCCAAGTGGAAGGTGCAGGTCCAGATCATGCCGGAACTGGATGC
GGAGAAGACCTCCTACAATCCGTTCGACCTCACCAAGGTGTGGCCCCACGGCGAGTATCCGCCCATCGACATCGGCGTGA
TGGAGCTGAACCGCAATCCGGAGAATTATTTCGCGGAGATCGAGCAGGCGGCGTTCTCACCGTCCAACATCGTGCCCGGC
ATCTCGTTCTCGCCGGACAAGATGCTGCAGGCCCGCATCTTCTCCTATGCGGATGCGCACCGCCACCGCATCGGCACCCA
TTACGAGCACCTGCCGGTGAACGCCCCCAAGTGCCCGGTCCATCACTATCACAAGGACGGCGCCATGCGCTTCTTCCCGC
AGGTGACGGGCAGCACCGATGCCTATTACGAGCCCAACTCGTTCGGCGGTGCGAAGGAAGACGCCAAATATGCCGAGCCT
CCGCTGAAGATCTCGGGCGATGCGGAACGCTACAACCACCGCATCGGCAATGACGACTTCTCCCAGCCGCGGGCGCTGTT
CGAGCTGTTCGATGCCGGCCAGCGGGCGCGCCTTTACTCCAACCTCGCGGCGGGCATGTACGGCATCCCGCAGGAGATCG
CGGACCGGCAGATCGCGCTGTTCACGCAGATCCACCCGGAATACGGGGCGGGGGTGCGCGCGGCGCTGGAGCAGGAAACC
CGCCAGAAGGCGGCGGAAACGGCGCAGCAGCAGAAGAATCCATCGGGTCCCGTCGCCGCCGAGTGA

Upstream 100 bases:

>100_bases
TTATCGAATCTTGAACGCAATCTGATTTGTAGTCAGTCCCGGAGACGCCCATCCTGCGCTCGTGATTTTCGCCCTCCGGG
CCTTTTCAGGGAGCCCATTC

Downstream 100 bases:

>100_bases
ACGGCCGGGAAGATGCGGGGGACGCCGGGCGGCTCACCGCCCGGCGCCCGGAAAGGGGATGGGCTCCGACCCATCCCCTT
TTTGATTCGCGGAGTCCTCG

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MTRPTLTTTAGNPIADNQNSLTAGERGPVLMQDYQLLEKLAHQNRERIPERVVHAKGWGAHGTLTITGDISKYTKAAALQ
PGAQTPMIARFSTVAGELGAADAERDVRGFALKFYTPEGNWDLVGNNTPVFFVRDPYKFPDFIHTQKRHPKTNLRSPTAM
WDFWSLSPESLHQVTILFSDRGLPVGVRNMNGYGSHTYSFVNAAGERFWVKFHFKTLQGHEHWTNAEATQVVGRTRESTQ
EDLFGAIEAGNFPKWKVQVQIMPELDAEKTSYNPFDLTKVWPHGEYPPIDIGVMELNRNPENYFAEIEQAAFSPSNIVPG
ISFSPDKMLQARIFSYADAHRHRIGTHYEHLPVNAPKCPVHHYHKDGAMRFFPQVTGSTDAYYEPNSFGGAKEDAKYAEP
PLKISGDAERYNHRIGNDDFSQPRALFELFDAGQRARLYSNLAAGMYGIPQEIADRQIALFTQIHPEYGAGVRAALEQET
RQKAAETAQQQKNPSGPVAAE

Sequences:

>Translated_501_residues
MTRPTLTTTAGNPIADNQNSLTAGERGPVLMQDYQLLEKLAHQNRERIPERVVHAKGWGAHGTLTITGDISKYTKAAALQ
PGAQTPMIARFSTVAGELGAADAERDVRGFALKFYTPEGNWDLVGNNTPVFFVRDPYKFPDFIHTQKRHPKTNLRSPTAM
WDFWSLSPESLHQVTILFSDRGLPVGVRNMNGYGSHTYSFVNAAGERFWVKFHFKTLQGHEHWTNAEATQVVGRTRESTQ
EDLFGAIEAGNFPKWKVQVQIMPELDAEKTSYNPFDLTKVWPHGEYPPIDIGVMELNRNPENYFAEIEQAAFSPSNIVPG
ISFSPDKMLQARIFSYADAHRHRIGTHYEHLPVNAPKCPVHHYHKDGAMRFFPQVTGSTDAYYEPNSFGGAKEDAKYAEP
PLKISGDAERYNHRIGNDDFSQPRALFELFDAGQRARLYSNLAAGMYGIPQEIADRQIALFTQIHPEYGAGVRAALEQET
RQKAAETAQQQKNPSGPVAAE
>Mature_500_residues
TRPTLTTTAGNPIADNQNSLTAGERGPVLMQDYQLLEKLAHQNRERIPERVVHAKGWGAHGTLTITGDISKYTKAAALQP
GAQTPMIARFSTVAGELGAADAERDVRGFALKFYTPEGNWDLVGNNTPVFFVRDPYKFPDFIHTQKRHPKTNLRSPTAMW
DFWSLSPESLHQVTILFSDRGLPVGVRNMNGYGSHTYSFVNAAGERFWVKFHFKTLQGHEHWTNAEATQVVGRTRESTQE
DLFGAIEAGNFPKWKVQVQIMPELDAEKTSYNPFDLTKVWPHGEYPPIDIGVMELNRNPENYFAEIEQAAFSPSNIVPGI
SFSPDKMLQARIFSYADAHRHRIGTHYEHLPVNAPKCPVHHYHKDGAMRFFPQVTGSTDAYYEPNSFGGAKEDAKYAEPP
LKISGDAERYNHRIGNDDFSQPRALFELFDAGQRARLYSNLAAGMYGIPQEIADRQIALFTQIHPEYGAGVRAALEQETR
QKAAETAQQQKNPSGPVAAE

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=482, Percent_Identity=50.4149377593361, Blast_Score=493, Evalue=1e-139,
Organism=Escherichia coli, GI48994891, Length=416, Percent_Identity=44.9519230769231, Blast_Score=352, Evalue=4e-98,
Organism=Caenorhabditis elegans, GI71998444, Length=481, Percent_Identity=52.1829521829522, Blast_Score=501, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI25151141, Length=478, Percent_Identity=51.8828451882845, Blast_Score=495, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI25147792, Length=479, Percent_Identity=51.5657620041754, Blast_Score=494, Evalue=1e-140,
Organism=Saccharomyces cerevisiae, GI6320462, Length=489, Percent_Identity=43.3537832310838, Blast_Score=375, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6321525, Length=504, Percent_Identity=37.8968253968254, Blast_Score=316, Evalue=5e-87,
Organism=Drosophila melanogaster, GI17981717, Length=469, Percent_Identity=48.1876332622601, Blast_Score=454, Evalue=1e-128,
Organism=Drosophila melanogaster, GI19920968, Length=476, Percent_Identity=43.0672268907563, Blast_Score=416, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 56143; Mature: 56012

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS00437 CATALASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPTLTTTAGNPIADNQNSLTAGERGPVLMQDYQLLEKLAHQNRERIPERVVHAKGWGA
CCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
HGTLTITGDISKYTKAAALQPGAQTPMIARFSTVAGELGAADAERDVRGFALKFYTPEGN
CEEEEEEECHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCC
WDLVGNNTPVFFVRDPYKFPDFIHTQKRHPKTNLRSPTAMWDFWSLSPESLHQVTILFSD
EEEECCCCCEEEEECCCCCCHHHHHHCCCCCCCCCCCCCEEEECCCCHHHCEEEEEEEEC
RGLPVGVRNMNGYGSHTYSFVNAAGERFWVKFHFKTLQGHEHWTNAEATQVVGRTRESTQ
CCCEEEEECCCCCCCHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCHHHHHHHCCHHHHH
EDLFGAIEAGNFPKWKVQVQIMPELDAEKTSYNPFDLTKVWPHGEYPPIDIGVMELNRNP
HHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCEEEEEEECCCH
ENYFAEIEQAAFSPSNIVPGISFSPDKMLQARIFSYADAHRHRIGTHYEHLPVNAPKCPV
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
HHYHKDGAMRFFPQVTGSTDAYYEPNSFGGAKEDAKYAEPPLKISGDAERYNHRIGNDDF
CCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHCCCCEEECCCHHHHHCCCCCCCC
SQPRALFELFDAGQRARLYSNLAAGMYGIPQEIADRQIALFTQIHPEYGAGVRAALEQET
CHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHCCCEEEEEEEECCCCCCCHHHHHHHHH
RQKAAETAQQQKNPSGPVAAE
HHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TRPTLTTTAGNPIADNQNSLTAGERGPVLMQDYQLLEKLAHQNRERIPERVVHAKGWGA
CCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
HGTLTITGDISKYTKAAALQPGAQTPMIARFSTVAGELGAADAERDVRGFALKFYTPEGN
CEEEEEEECHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCC
WDLVGNNTPVFFVRDPYKFPDFIHTQKRHPKTNLRSPTAMWDFWSLSPESLHQVTILFSD
EEEECCCCCEEEEECCCCCCHHHHHHCCCCCCCCCCCCCEEEECCCCHHHCEEEEEEEEC
RGLPVGVRNMNGYGSHTYSFVNAAGERFWVKFHFKTLQGHEHWTNAEATQVVGRTRESTQ
CCCEEEEECCCCCCCHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCHHHHHHHCCHHHHH
EDLFGAIEAGNFPKWKVQVQIMPELDAEKTSYNPFDLTKVWPHGEYPPIDIGVMELNRNP
HHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCEEEEEEECCCH
ENYFAEIEQAAFSPSNIVPGISFSPDKMLQARIFSYADAHRHRIGTHYEHLPVNAPKCPV
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
HHYHKDGAMRFFPQVTGSTDAYYEPNSFGGAKEDAKYAEPPLKISGDAERYNHRIGNDDF
CCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHCCCCEEECCCHHHHHCCCCCCCC
SQPRALFELFDAGQRARLYSNLAAGMYGIPQEIADRQIALFTQIHPEYGAGVRAALEQET
CHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHCCCEEEEEEEECCCCCCCHHHHHHHHH
RQKAAETAQQQKNPSGPVAAE
HHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961511 [H]