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The map label for this gene is luxO [H]

Identifier: 154246239

GI number: 154246239

Start: 2560951

End: 2562387

Strand: Reverse

Name: luxO [H]

Synonym: Xaut_2297

Alternate gene names: 154246239

Gene position: 2562387-2560951 (Counterclockwise)

Preceding gene: 154246240

Following gene: 154246235

Centisome position: 48.27

GC content: 70.7

Gene sequence:

>1437_bases
ATGGCCATCGGGTCTTCTTGCCATAACATTTTACCACGAACAGATGCCATGATTGTAAATCCTTCGGCCCTCCAGACCGA
CCGGCGCACCTGCGTTCTGGTCTGCGACCCGGAATCGGACGTGCGCACCATGATGCGTGCCGCGTTCGCCCGGCGCGATG
CCTTGCATGTGCTGGAAGCGGAGGATCTCGCTGCGGCCTTGCCCCTGGCGCCGCGCTGCGCGTCCATCCTGCTGGCGGCG
GACCACCCGGAAGAGGCGACCCGGCGGCTGCGGGCTGCGGGCTTTGGCGGAACGCTGGTGGTGGCGCTGGCCCATGGCGC
TTCGGTGGGGGATGCCGTTGGGGCCATGCGCGCCGGCGCCGACGACGTGGTGATCAAGCCCATCGGTCCCGAGGACGTGG
TGGACCGCCTGCTGGCGTCCACCCCGGCCCGTCGTCCGGAGCGGCGGCGGCGCGACCGGCCGCAACTGCCGCGCAATGGC
GACTTCTGCGGCTTCCTCGGCCGCTCGCCGGCCATGCAGGCGGTTTATGAACAGATCGAGCGGCTGGCCGCGTCGCGGGC
GCCGGTGTTCGTGACCGGAGAGAGCGGCACCGGCAAGGGCTTGGCTGCGGCTGCCCTTCATGTGGCATCGACCCGGCAGG
AAGGCCCCTTCAACGCCCTCAACTGCGCCGCCATCCCGGCGAGCTATCTGGAGCAGGCCGTGTTCGGCCTGACCGGCCCC
GGCGCCATCGAGCGCGCCCACGGCGGCACGCTGCTGATCGAGGAGGTGTCGGAGCTGAACAGCGCCACCCAAAGCAAGCT
GCTCCATTTCCTGGAGAAAGGCCGCTTCCGCCGGGCCGGCGAGACGGACGAGCGCACCAGCGACGTGCGTCTGATCTGCG
CCACGGTCCGCGATCCGCTGGAGGACGTGCGTGTCGGCCGCCTGCGCGAAGACCTGTTCTACCGGCTGAACGTCCTCACC
CTGGCCCTGCCGCCGCTGCGCGAGCGCGACGACGACGTGATTCTCCTTGCGGAAGCCTTCCTGGCCCGCTTCGCCGGCGA
GGAAGGCCGGCCCATTTCCCGGCTCGGCCCCGGCGCGGCCGAGGTGCTGCGGGCCCGCAGCTTCCCCGGCAACGTGCGGG
AACTGCAGAACCTGATGCGGCGCGCGGTCATTCTCGGCGACGGCGGATTGCTCGGACCCGAGCTGTTCGAGGAGACCGAG
CCGGCGCAGCCGGAGGAGGCGCCCCGCACCCAGTTGGCCGCCATGCTGATCGACGCCGCGCAAGGCGGCACGTTCGGCCG
GGTCGAGCCCTTCGCCGTCGTGGAGCGGCGGGTGATCGAGGCAGCCATCGCCGCCTTTGACGGCAACATCCCGCTGGCCG
CTGCGGCCCTCGACCTCAGCCCCTCCACCCTCTACCGCAAGAAACTCGCCTGGCAGGACCGGCGCCGGCTCTCGTGA

Upstream 100 bases:

>100_bases
ATGCTCTGAGTTCTTGTTTTCATGCCTTTTCACCCTGCAGTATCCTAACTTAACTCCGTCCTGAAACGCTGCAGAGACCG
GATCGGCAGCTTGGTCTAGT

Downstream 100 bases:

>100_bases
GAGAGAGGCCGACGCCTGCGTGAGACGATCCTGCCAGAGGATCGCTGCCTCGGAGTTGCCCGCCTCAGAGGATGAAGCGG
CTCAGGTCGGCGTTGCGGGC

Product: two component sigma54 specific Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MAIGSSCHNILPRTDAMIVNPSALQTDRRTCVLVCDPESDVRTMMRAAFARRDALHVLEAEDLAAALPLAPRCASILLAA
DHPEEATRRLRAAGFGGTLVVALAHGASVGDAVGAMRAGADDVVIKPIGPEDVVDRLLASTPARRPERRRRDRPQLPRNG
DFCGFLGRSPAMQAVYEQIERLAASRAPVFVTGESGTGKGLAAAALHVASTRQEGPFNALNCAAIPASYLEQAVFGLTGP
GAIERAHGGTLLIEEVSELNSATQSKLLHFLEKGRFRRAGETDERTSDVRLICATVRDPLEDVRVGRLREDLFYRLNVLT
LALPPLRERDDDVILLAEAFLARFAGEEGRPISRLGPGAAEVLRARSFPGNVRELQNLMRRAVILGDGGLLGPELFEETE
PAQPEEAPRTQLAAMLIDAAQGGTFGRVEPFAVVERRVIEAAIAAFDGNIPLAAAALDLSPSTLYRKKLAWQDRRRLS

Sequences:

>Translated_478_residues
MAIGSSCHNILPRTDAMIVNPSALQTDRRTCVLVCDPESDVRTMMRAAFARRDALHVLEAEDLAAALPLAPRCASILLAA
DHPEEATRRLRAAGFGGTLVVALAHGASVGDAVGAMRAGADDVVIKPIGPEDVVDRLLASTPARRPERRRRDRPQLPRNG
DFCGFLGRSPAMQAVYEQIERLAASRAPVFVTGESGTGKGLAAAALHVASTRQEGPFNALNCAAIPASYLEQAVFGLTGP
GAIERAHGGTLLIEEVSELNSATQSKLLHFLEKGRFRRAGETDERTSDVRLICATVRDPLEDVRVGRLREDLFYRLNVLT
LALPPLRERDDDVILLAEAFLARFAGEEGRPISRLGPGAAEVLRARSFPGNVRELQNLMRRAVILGDGGLLGPELFEETE
PAQPEEAPRTQLAAMLIDAAQGGTFGRVEPFAVVERRVIEAAIAAFDGNIPLAAAALDLSPSTLYRKKLAWQDRRRLS
>Mature_477_residues
AIGSSCHNILPRTDAMIVNPSALQTDRRTCVLVCDPESDVRTMMRAAFARRDALHVLEAEDLAAALPLAPRCASILLAAD
HPEEATRRLRAAGFGGTLVVALAHGASVGDAVGAMRAGADDVVIKPIGPEDVVDRLLASTPARRPERRRRDRPQLPRNGD
FCGFLGRSPAMQAVYEQIERLAASRAPVFVTGESGTGKGLAAAALHVASTRQEGPFNALNCAAIPASYLEQAVFGLTGPG
AIERAHGGTLLIEEVSELNSATQSKLLHFLEKGRFRRAGETDERTSDVRLICATVRDPLEDVRVGRLREDLFYRLNVLTL
ALPPLRERDDDVILLAEAFLARFAGEEGRPISRLGPGAAEVLRARSFPGNVRELQNLMRRAVILGDGGLLGPELFEETEP
AQPEEAPRTQLAAMLIDAAQGGTFGRVEPFAVVERRVIEAAIAAFDGNIPLAAAALDLSPSTLYRKKLAWQDRRRLS

Specific function: Involved in the regulation of different processes depending on the cell density. Acts together with sigma-54 to repress, perhaps indirectly, some genes [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=462, Percent_Identity=35.4978354978355, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1787583, Length=236, Percent_Identity=46.6101694915254, Blast_Score=205, Evalue=6e-54,
Organism=Escherichia coli, GI1790437, Length=381, Percent_Identity=35.4330708661417, Blast_Score=195, Evalue=6e-51,
Organism=Escherichia coli, GI87082152, Length=323, Percent_Identity=39.6284829721362, Blast_Score=181, Evalue=9e-47,
Organism=Escherichia coli, GI1790299, Length=477, Percent_Identity=32.9140461215933, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1789087, Length=267, Percent_Identity=39.7003745318352, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI87082117, Length=251, Percent_Identity=40.2390438247012, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1789233, Length=325, Percent_Identity=34.7692307692308, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1788905, Length=318, Percent_Identity=35.8490566037736, Blast_Score=162, Evalue=6e-41,
Organism=Escherichia coli, GI1786524, Length=326, Percent_Identity=36.8098159509202, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI87081872, Length=234, Percent_Identity=40.5982905982906, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1789828, Length=255, Percent_Identity=31.3725490196078, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI87081858, Length=299, Percent_Identity=29.7658862876254, Blast_Score=89, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51539; Mature: 51407

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIGSSCHNILPRTDAMIVNPSALQTDRRTCVLVCDPESDVRTMMRAAFARRDALHVLEA
CCCCCCHHHCCCCCCEEEECCHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
EDLAAALPLAPRCASILLAADHPEEATRRLRAAGFGGTLVVALAHGASVGDAVGAMRAGA
HHHHHHCCCCHHHHHHEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCC
DDVVIKPIGPEDVVDRLLASTPARRPERRRRDRPQLPRNGDFCGFLGRSPAMQAVYEQIE
CCEEEECCCHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHH
RLAASRAPVFVTGESGTGKGLAAAALHVASTRQEGPFNALNCAAIPASYLEQAVFGLTGP
HHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHCCCCC
GAIERAHGGTLLIEEVSELNSATQSKLLHFLEKGRFRRAGETDERTSDVRLICATVRDPL
CHHECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHEEHHHHHCCH
EDVRVGRLREDLFYRLNVLTLALPPLRERDDDVILLAEAFLARFAGEEGRPISRLGPGAA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHCCCCCCCHHHCCCCHH
EVLRARSFPGNVRELQNLMRRAVILGDGGLLGPELFEETEPAQPEEAPRTQLAAMLIDAA
HHHHHCCCCCCHHHHHHHHHHHEEECCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHH
QGGTFGRVEPFAVVERRVIEAAIAAFDGNIPLAAAALDLSPSTLYRKKLAWQDRRRLS
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AIGSSCHNILPRTDAMIVNPSALQTDRRTCVLVCDPESDVRTMMRAAFARRDALHVLEA
CCCCCHHHCCCCCCEEEECCHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
EDLAAALPLAPRCASILLAADHPEEATRRLRAAGFGGTLVVALAHGASVGDAVGAMRAGA
HHHHHHCCCCHHHHHHEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCC
DDVVIKPIGPEDVVDRLLASTPARRPERRRRDRPQLPRNGDFCGFLGRSPAMQAVYEQIE
CCEEEECCCHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHH
RLAASRAPVFVTGESGTGKGLAAAALHVASTRQEGPFNALNCAAIPASYLEQAVFGLTGP
HHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHCCCCC
GAIERAHGGTLLIEEVSELNSATQSKLLHFLEKGRFRRAGETDERTSDVRLICATVRDPL
CHHECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHEEHHHHHCCH
EDVRVGRLREDLFYRLNVLTLALPPLRERDDDVILLAEAFLARFAGEEGRPISRLGPGAA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHCCCCCCCHHHCCCCHH
EVLRARSFPGNVRELQNLMRRAVILGDGGLLGPELFEETEPAQPEEAPRTQLAAMLIDAA
HHHHHCCCCCCHHHHHHHHHHHEEECCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHH
QGGTFGRVEPFAVVERRVIEAAIAAFDGNIPLAAAALDLSPSTLYRKKLAWQDRRRLS
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301; 9748465 [H]