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The map label for this gene is intA [H]

Identifier: 154246176

GI number: 154246176

Start: 2494740

End: 2495933

Strand: Direct

Name: intA [H]

Synonym: Xaut_2233

Alternate gene names: 154246176

Gene position: 2494740-2495933 (Clockwise)

Preceding gene: 154246171

Following gene: 154246177

Centisome position: 46.99

GC content: 63.07

Gene sequence:

>1194_bases
ATGGCCCTTACCGACCTCGCTTTGCGCAACGCGAAGCCCAGGGACAAAGCCTATAAATTGTTCGATGGCGGCGGCCTCCA
CCTGCTCGTCAATCCCAACGGAAGCCGAATCTGGCGCCTCGCCTATCGCTTCGCCGGCAAGCCGAAGCAGATTTCCTTCG
GCCCCTATCCCACCGTTTCGTTGGCCGAGGCGCGCGAAAAGCGGGAAGACGCCAAAAAGCAGTTGCTCGACAACAAGGAC
CCCACCACCGTCCGCAAGGTCGAGAAGGTGACGGCCGCCATTTCCGAAGGCAACACCTTCTCCCGTCTGGTCGGCGAGTA
CATCGAACGGCTCGAGATGCGGAACTCGGCCCCCGCGACGGTTACAAAAAACAGGTGGCTGCTGGAAAATTTGGCGGGTC
CCGCACTGGGTCGCCGGCCGATCAGCGAAATCACTCCCTTCGAGGTTCTGGCCGTGTTGCAGCAGGTGGAACGCAGCGGC
CGGCGCGAATCAGCCCGTCGCCTGCGCTCGGCCATCGGCAGCGTGTTCCGTTTCGCTATTGCCACGCTTCGCGCCCAGCA
TGATCCGACATCTGCGCTGAAGGACGCGCTTGAGCGCCCGAAAGTGAAGCATCGCTCCGCCCTCACCGATCCGAAGCAGC
TCGGCGGCCTCATGCGCTCCATCGATGAGTATGACGGCTGGCCGACGCTGCGATCGGCGATGCTCTTTACGGCGCTGACC
TTTGCTCGGCCGGGCGAGGTCCGTGGCGCACGATGGAGAGAGATCGACCTCGACAAGGCCGTGTGGAGTATCCCTGCGGA
ACGCATGAAGATGCGACGGGCTCACGTCGTGCCTCTTTCCCGCCAGGCGCTGGAGGTGCTCAGCGAAATCAGGCCGCTGA
GCGGAAGCAGTGAGCTGATCTTCCCTTCCATCCGCTCGAACAAGAAGATCCTGAGCGAGAACGCCATGAACTCGGCGCTG
CGCCGCATGGGGTTCACGCAAGAGGAGATGACTGCCCACGGCTTCCGGGCGGCGGCCAGTTCGATCTTGAACGAGAAGGG
CCATTCGCCCGACGTGATCGAGGCTGCCTTGGGCCATCTCGACCAGAACGAGGTGCGTCGGGCCTATAACCGGGCCACCT
ACTGGCCGGAGCGCGTCGTCCTAATGCAGGCATGGGCGGACATGCTGGACGCGTTTCGCGCTCTCAAGGGCTGA

Upstream 100 bases:

>100_bases
AATGGTCCATCGGGGTCCATTGAGATCCGGTTGTATCTCGCGCGCGTGTAGGCATTCTTGTAGGCATCGCGGCCATGCCT
ACAAGGGGAGATGCCTACAG

Downstream 100 bases:

>100_bases
TGCAGTCCCGAACGAGAGCCAGAGCGGCTCCCTATTTGAGTTTCGTAAAAAAGTTTTCGCCAAAAGACTATTAAATTCAA
TCTATTATCGACATGATATC

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MALTDLALRNAKPRDKAYKLFDGGGLHLLVNPNGSRIWRLAYRFAGKPKQISFGPYPTVSLAEAREKREDAKKQLLDNKD
PTTVRKVEKVTAAISEGNTFSRLVGEYIERLEMRNSAPATVTKNRWLLENLAGPALGRRPISEITPFEVLAVLQQVERSG
RRESARRLRSAIGSVFRFAIATLRAQHDPTSALKDALERPKVKHRSALTDPKQLGGLMRSIDEYDGWPTLRSAMLFTALT
FARPGEVRGARWREIDLDKAVWSIPAERMKMRRAHVVPLSRQALEVLSEIRPLSGSSELIFPSIRSNKKILSENAMNSAL
RRMGFTQEEMTAHGFRAAASSILNEKGHSPDVIEAALGHLDQNEVRRAYNRATYWPERVVLMQAWADMLDAFRALKG

Sequences:

>Translated_397_residues
MALTDLALRNAKPRDKAYKLFDGGGLHLLVNPNGSRIWRLAYRFAGKPKQISFGPYPTVSLAEAREKREDAKKQLLDNKD
PTTVRKVEKVTAAISEGNTFSRLVGEYIERLEMRNSAPATVTKNRWLLENLAGPALGRRPISEITPFEVLAVLQQVERSG
RRESARRLRSAIGSVFRFAIATLRAQHDPTSALKDALERPKVKHRSALTDPKQLGGLMRSIDEYDGWPTLRSAMLFTALT
FARPGEVRGARWREIDLDKAVWSIPAERMKMRRAHVVPLSRQALEVLSEIRPLSGSSELIFPSIRSNKKILSENAMNSAL
RRMGFTQEEMTAHGFRAAASSILNEKGHSPDVIEAALGHLDQNEVRRAYNRATYWPERVVLMQAWADMLDAFRALKG
>Mature_396_residues
ALTDLALRNAKPRDKAYKLFDGGGLHLLVNPNGSRIWRLAYRFAGKPKQISFGPYPTVSLAEAREKREDAKKQLLDNKDP
TTVRKVEKVTAAISEGNTFSRLVGEYIERLEMRNSAPATVTKNRWLLENLAGPALGRRPISEITPFEVLAVLQQVERSGR
RESARRLRSAIGSVFRFAIATLRAQHDPTSALKDALERPKVKHRSALTDPKQLGGLMRSIDEYDGWPTLRSAMLFTALTF
ARPGEVRGARWREIDLDKAVWSIPAERMKMRRAHVVPLSRQALEVLSEIRPLSGSSELIFPSIRSNKKILSENAMNSALR
RMGFTQEEMTAHGFRAAASSILNEKGHSPDVIEAALGHLDQNEVRRAYNRATYWPERVVLMQAWADMLDAFRALKG

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=393, Percent_Identity=39.1857506361323, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI145693166, Length=398, Percent_Identity=35.929648241206, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1788690, Length=389, Percent_Identity=33.1619537275064, Blast_Score=206, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 44674; Mature: 44543

Theoretical pI: Translated: 10.94; Mature: 10.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTDLALRNAKPRDKAYKLFDGGGLHLLVNPNGSRIWRLAYRFAGKPKQISFGPYPTVS
CCCHHHHHHCCCCCHHHEEEECCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCHH
LAEAREKREDAKKQLLDNKDPTTVRKVEKVTAAISEGNTFSRLVGEYIERLEMRNSAPAT
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCC
VTKNRWLLENLAGPALGRRPISEITPFEVLAVLQQVERSGRRESARRLRSAIGSVFRFAI
CCCCHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ATLRAQHDPTSALKDALERPKVKHRSALTDPKQLGGLMRSIDEYDGWPTLRSAMLFTALT
HHHHHCCCCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
FARPGEVRGARWREIDLDKAVWSIPAERMKMRRAHVVPLSRQALEVLSEIRPLSGSSELI
HCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEE
FPSIRSNKKILSENAMNSALRRMGFTQEEMTAHGFRAAASSILNEKGHSPDVIEAALGHL
ECCHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
DQNEVRRAYNRATYWPERVVLMQAWADMLDAFRALKG
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALTDLALRNAKPRDKAYKLFDGGGLHLLVNPNGSRIWRLAYRFAGKPKQISFGPYPTVS
CCHHHHHHCCCCCHHHEEEECCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCHH
LAEAREKREDAKKQLLDNKDPTTVRKVEKVTAAISEGNTFSRLVGEYIERLEMRNSAPAT
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCC
VTKNRWLLENLAGPALGRRPISEITPFEVLAVLQQVERSGRRESARRLRSAIGSVFRFAI
CCCCHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ATLRAQHDPTSALKDALERPKVKHRSALTDPKQLGGLMRSIDEYDGWPTLRSAMLFTALT
HHHHHCCCCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
FARPGEVRGARWREIDLDKAVWSIPAERMKMRRAHVVPLSRQALEVLSEIRPLSGSSELI
HCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEE
FPSIRSNKKILSENAMNSALRRMGFTQEEMTAHGFRAAASSILNEKGHSPDVIEAALGHL
ECCHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
DQNEVRRAYNRATYWPERVVLMQAWADMLDAFRALKG
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]