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The map label for this gene is visC [C]

Identifier: 154246154

GI number: 154246154

Start: 2473520

End: 2474812

Strand: Direct

Name: visC [C]

Synonym: Xaut_2211

Alternate gene names: 154246154

Gene position: 2473520-2474812 (Clockwise)

Preceding gene: 154246139

Following gene: 154246156

Centisome position: 46.59

GC content: 71.15

Gene sequence:

>1293_bases
ATGACCGGGCTGACCATGTCCGAGCCTCAGGCCGAGATGCCGCACGCCGGAGCCGGCTTTGCCGCCACCGCGGCCGCGCC
GCGTGCGGACGTGGCCATCGTCGGTGGCGGGCTCGCCGGCCTCAGCCTTGCGCTCGCCCTGCGCCAGGGGCTGGGGCCTG
ATGCCGACATCGTGCTGTTCGACCCCTATTTGTCCCACGCCACGGTGGATGACGGCCGCTGCTCGGCCATCGCCGCCGGT
GCGCGGCGCATGCTCACCACCCTCGGTGTGTGGCAGCACGTGGGTGCCAAGGCCCAGCCCATCCAGGCCATGGTGGTCAC
CGACAGCCGCACCAAGGACGTGGCGCGCCCCACCTTCCTGACCTTCGACGGCGATGTGGAGCCGGGCGAGGCCTTCGCCC
ACATGGTGCCCAACGCCGACCTGCAGTACGCCCTCATCGATGCGGCGCGCTCCGCCGGCATCGACCTGCGCGCCCAGTCC
GTGGACGATTTCACCGCCGACCGTTCCGGCGTGAGCCTTTCCGCCGCCGGGGCGCCGACGCTTCGGGCCCAGCTTCTGGT
GGCTTGCGATGGCGCCAAGTCGCGCATCCGCGGCATGGCCGGCATCGCCAATGTGGCCTGGGGCTATGGCCAGAGCGGCA
TCACCTTCGCGGTGGAGCACGAACGGCCCCACGAGGGCCGGGCGGAAGAGCATTTTTTGCCCCCCGGCCCGTTCGCCATC
CTGCCCTTGCCAGGCAACCGCTCCTCCATCGTGTGGACCGAGCGCACGGAGGATGCCGAGCGCATCGTGGGACTGCCGTC
CATCGTCTTCCAGGAAGAGCTGGAGCAGCGATTCGGCCACCGGCTCGGCTGGGTGAAGCCGGTGACCAAGCCGCGTGCCT
ATCCTTTGGGCTTCGCCATGGCGCGCAGCTTCATCGGCGAGCGCCTCGCTTTGGTGGGGGATGCGGCCCATCTCATCCAC
CCCATTGCCGGGCAGGGGCTCAACATGGGCCTGCGCGACGTGGCGGCACTGGCCGAGGCGGTGACGGACGCCGCGCGGGT
GGGCCTCGATTTCGCCGGGCCGGCGGTGCTGGAGCGCTATCAGCGCTGGCGGCGGTTCGACACCTTGGCCATGGGCGTCG
CGACAGACGGGCTCAACCGGCTGTTCTCGAACCGCTCCGACGCCCTGCGCGCGGTGCGCGACCTCGGGCTCGGCCTCGTG
GACCGGATGCCGCGCCTCAAGGGCCTGTTCATCCGCGACGCAGCGGGCCTCACCGGGCAGGTGCCGAAGCTGCTGCGGGG
CGAGGCGCTTTAG

Upstream 100 bases:

>100_bases
GCCGCCTTCCCTTTAGGGTGGGACGAAGCGCGGCGGAACGGATAGAGGATCGGCGCCGGCCGGCGGGCCCGCCGCGAAAC
AGGTTCGAGGGAGTGAAGCG

Downstream 100 bases:

>100_bases
AGATCCGCTCCCCGCTCAGGGGGCAGGGCGCGGATGCCCTGTCCTCAGCGGGAGAGTTCGCTCTCGTCGAGCTTGCGGGC
CTCGTCGGCCAGCATGATCG

Product: 2-octaprenyl-6-methoxyphenyl hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MTGLTMSEPQAEMPHAGAGFAATAAAPRADVAIVGGGLAGLSLALALRQGLGPDADIVLFDPYLSHATVDDGRCSAIAAG
ARRMLTTLGVWQHVGAKAQPIQAMVVTDSRTKDVARPTFLTFDGDVEPGEAFAHMVPNADLQYALIDAARSAGIDLRAQS
VDDFTADRSGVSLSAAGAPTLRAQLLVACDGAKSRIRGMAGIANVAWGYGQSGITFAVEHERPHEGRAEEHFLPPGPFAI
LPLPGNRSSIVWTERTEDAERIVGLPSIVFQEELEQRFGHRLGWVKPVTKPRAYPLGFAMARSFIGERLALVGDAAHLIH
PIAGQGLNMGLRDVAALAEAVTDAARVGLDFAGPAVLERYQRWRRFDTLAMGVATDGLNRLFSNRSDALRAVRDLGLGLV
DRMPRLKGLFIRDAAGLTGQVPKLLRGEAL

Sequences:

>Translated_430_residues
MTGLTMSEPQAEMPHAGAGFAATAAAPRADVAIVGGGLAGLSLALALRQGLGPDADIVLFDPYLSHATVDDGRCSAIAAG
ARRMLTTLGVWQHVGAKAQPIQAMVVTDSRTKDVARPTFLTFDGDVEPGEAFAHMVPNADLQYALIDAARSAGIDLRAQS
VDDFTADRSGVSLSAAGAPTLRAQLLVACDGAKSRIRGMAGIANVAWGYGQSGITFAVEHERPHEGRAEEHFLPPGPFAI
LPLPGNRSSIVWTERTEDAERIVGLPSIVFQEELEQRFGHRLGWVKPVTKPRAYPLGFAMARSFIGERLALVGDAAHLIH
PIAGQGLNMGLRDVAALAEAVTDAARVGLDFAGPAVLERYQRWRRFDTLAMGVATDGLNRLFSNRSDALRAVRDLGLGLV
DRMPRLKGLFIRDAAGLTGQVPKLLRGEAL
>Mature_429_residues
TGLTMSEPQAEMPHAGAGFAATAAAPRADVAIVGGGLAGLSLALALRQGLGPDADIVLFDPYLSHATVDDGRCSAIAAGA
RRMLTTLGVWQHVGAKAQPIQAMVVTDSRTKDVARPTFLTFDGDVEPGEAFAHMVPNADLQYALIDAARSAGIDLRAQSV
DDFTADRSGVSLSAAGAPTLRAQLLVACDGAKSRIRGMAGIANVAWGYGQSGITFAVEHERPHEGRAEEHFLPPGPFAIL
PLPGNRSSIVWTERTEDAERIVGLPSIVFQEELEQRFGHRLGWVKPVTKPRAYPLGFAMARSFIGERLALVGDAAHLIHP
IAGQGLNMGLRDVAALAEAVTDAARVGLDFAGPAVLERYQRWRRFDTLAMGVATDGLNRLFSNRSDALRAVRDLGLGLVD
RMPRLKGLFIRDAAGLTGQVPKLLRGEAL

Specific function: Not Yet Known. [C]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=383, Percent_Identity=28.1984334203655, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI32967307, Length=271, Percent_Identity=31.3653136531365, Blast_Score=132, Evalue=9e-31,
Organism=Escherichia coli, GI1789273, Length=406, Percent_Identity=34.7290640394089, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI1786883, Length=400, Percent_Identity=34.75, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1789274, Length=374, Percent_Identity=36.6310160427808, Blast_Score=177, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI25146631, Length=458, Percent_Identity=27.292576419214, Blast_Score=135, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6321694, Length=465, Percent_Identity=25.8064516129032, Blast_Score=114, Evalue=4e-26,
Organism=Drosophila melanogaster, GI19920760, Length=389, Percent_Identity=28.2776349614396, Blast_Score=140, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 45642; Mature: 45511

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLTMSEPQAEMPHAGAGFAATAAAPRADVAIVGGGLAGLSLALALRQGLGPDADIVLF
CCCCCCCCCCCCCCCCCCCCCHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCEEEE
DPYLSHATVDDGRCSAIAAGARRMLTTLGVWQHVGAKAQPIQAMVVTDSRTKDVARPTFL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEE
TFDGDVEPGEAFAHMVPNADLQYALIDAARSAGIDLRAQSVDDFTADRSGVSLSAAGAPT
EECCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEECCCCCHHCCCCCCEEECCCCCH
LRAQLLVACDGAKSRIRGMAGIANVAWGYGQSGITFAVEHERPHEGRAEEHFLPPGPFAI
HEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEE
LPLPGNRSSIVWTERTEDAERIVGLPSIVFQEELEQRFGHRLGWVKPVTKPRAYPLGFAM
EECCCCCCEEEEECCCCCHHHHHCCHHHHHHHHHHHHHCHHCCCCCCCCCCCCCCHHHHH
ARSFIGERLALVGDAAHLIHPIAGQGLNMGLRDVAALAEAVTDAARVGLDFAGPAVLERY
HHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
QRWRRFDTLAMGVATDGLNRLFSNRSDALRAVRDLGLGLVDRMPRLKGLFIRDAAGLTGQ
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHCCHHHCEEEECCCCCCCC
VPKLLRGEAL
CHHHHCCCCC
>Mature Secondary Structure 
TGLTMSEPQAEMPHAGAGFAATAAAPRADVAIVGGGLAGLSLALALRQGLGPDADIVLF
CCCCCCCCCCCCCCCCCCCCHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCEEEE
DPYLSHATVDDGRCSAIAAGARRMLTTLGVWQHVGAKAQPIQAMVVTDSRTKDVARPTFL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEE
TFDGDVEPGEAFAHMVPNADLQYALIDAARSAGIDLRAQSVDDFTADRSGVSLSAAGAPT
EECCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEECCCCCHHCCCCCCEEECCCCCH
LRAQLLVACDGAKSRIRGMAGIANVAWGYGQSGITFAVEHERPHEGRAEEHFLPPGPFAI
HEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEE
LPLPGNRSSIVWTERTEDAERIVGLPSIVFQEELEQRFGHRLGWVKPVTKPRAYPLGFAM
EECCCCCCEEEEECCCCCHHHHHCCHHHHHHHHHHHHHCHHCCCCCCCCCCCCCCHHHHH
ARSFIGERLALVGDAAHLIHPIAGQGLNMGLRDVAALAEAVTDAARVGLDFAGPAVLERY
HHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
QRWRRFDTLAMGVATDGLNRLFSNRSDALRAVRDLGLGLVDRMPRLKGLFIRDAAGLTGQ
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHCCHHHCEEEECCCCCCCC
VPKLLRGEAL
CHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]